Clinical trials: Flap Disorder
Fistula of Soft Palate (Disorder)
Evaluation of the Incidence of Palatal Fistula in Furlow Double-opposing Z-plasty vs. Two-flap Palatoplasty for Cleft Palate Repair
Evaluation of the incidence of palatal fistula in Furlow double-opposing z-plasty versus two-flap palatoplasty for cleft palate repair.
- Trial name
- NCT03055637
- Testing
- Furlow double opposing z-plasty, Two flap palatoplasty
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sarah Moustafa Mahmoud Fahmy El-Youtti
Implant Tissue Failure, Dental Implant Failed
Laterally Rotated Flap for Soft Tissue Augmentation Around Maxillary Loaded Osseointegrated Dental Implant
Peri-implant mucositis is one of the most common peri-implant diseases. It was reported in more than 20% of the subjects rehabilitated with dental implants (Lee et al. 2017; Rodrigo et al. 2018; Wada et al. 2019).
- Conditions
- Implant Tissue Failure, Dental Implant Failed, Peri-Implantitis
- Trial name
- NCT06206499
- Testing
- soft tissue augmentation
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Gingival Recession
Treatment of Multiple Gingival Recessions With a MCAF or a MCAT and a Collagen Matrix
In a recent meta-analysis, Graziani et al. reported that despite the "ideal" treatment for multiple gingival recession defects is not yet identified, there are some indirect suggestions from the analyzed data that, in comparison…
- Trial name
- NCT04225351
- Testing
- MCAF+CM, MCAT+CM
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Periodontal Pocket
Comparing Photodisinfection of Chitosan NP Enriched ICG Over ICG as Adjunct to OFD: RCT
The current study is a prospective randomised study-Comparison of photodisinfection with chitosan nanoparticles enriched indocyanine green over indocyanine green as an adjunct to open flap debridement in the management of stage…
- Trial name
- NCT06523244
- Testing
- PHOTODYNAMIC THERAPY
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
PRF, Hypospadias
A Multicenter Randomized Controlled Trial Comparing Platelet-Rich Fibrin and Ventral Dartos Flap as Intermediate Layers in Tabularized Incised Plate (TIP) Urethroplasty for Distal Hypospadias With Mild Penile Curvature
Distal hypospadias is the most common form of hypospadias. The Tubularized Incised Plate (TIP) repair is the standard surgical technique for this condition; however, complications such as fistula formation and meatal stenosis…
- Conditions
- PRF, Hypospadias, Distal Hypospadias, Hypospadias Repair
- Trial name
- PRF (NCT07045545)
- Testing
- - Group A: Platelet-rich fibrin membrane prepared intraoperatively and applied over neourethra, Group B: Ventral dartos flap rotated over neourethra
- Where
- Uzbekistan
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- National Children's Medical Center, Uzbekistan
Gingival Recession
Evaluation of Root Coverage After the Use of Coronally Advanced Flap Either With Advanced Paltelet Rich Fibrin or Subepithilial Connective Tissue Graft in Treatment of Miller Class I and II Gingival Recession.
patients with Miller class I , II gingival recession will be divided into 2 groups (control, intervention).the control one will receive coronally advanced flap with subepithililal connective tissue graft harvested from the palate…
- Trial name
- NCT03695549
- Testing
- CAF + (A-PRF), CAF+SCTG
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession, Localized
Tuberosity Versus Palatal Connective Tissue Graft on the Treatment of Single Maxillary Recession-type Defects
The goal of this randomized clinical study is to assess the root coverage outcomes and patient morbidity following the treatment of single maxillary recession-type defects using a coronally advanced flap (CAF) combined with a…
- Trial name
- NCT06404762
- Testing
- tSCTG+ CAF, pSCTG+ CAF
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Periodontal Diseases
Treatment of Periodontal Intrabony Defects With A-PRF or OFD
The aim of this randomized clinical trial was to clinically evaluate and compare the healing of intrabony defects after treatment with advanced platelet-rich fibrin (A-PRF+) toped flap debridement (OFD) in periodontitis patients.
- Trial name
- NCT04823572
- Testing
- A-PRF/OFD
- Where
- Hungary
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Gingival Recession
Clinical Evaluation of Single-stage Advanced Versus Rotated Flaps in the Treatment of Gingival Recessions
BACKGROUND: Several procedures have been reported for the surgical correction of gingival recession (GR), including the laterally positioned flap (LPF) and the coronally advanced flap (CAF), performed as single or two-stage…
- Trial name
- NCT02433912
- Testing
- Test - Laterally positioned flap, Control-Coronally positioned flap, 750 mg paracetamol
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Gingival Recession
Xenogeneic Collagen Matrix or Palatal Connective Tissue Graft With a Coronally Advanced Flap in Class III Recessions
The purpose of this multi-center study is to compare the effectiveness of Mucograft versus connective tissue graft in combination with coronal advanced flap for the treatment of Miller class III recessions The connective tissue…
- Trial name
- NCT03344315
- Testing
- experimental: collagen matrix, Active Comparator: autologous connective tissue graft
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Gingival Recession
Effect of Suturing Protocols on Coronally Advanced Flap for Root Coverage Outcomes
The purpose of this retrospective study is to investigate whether suturing protocols (suture removal timing) influence root coverage outcomes in recession defects treated with a coronally advanced flap (CAF) procedure.
- Trial name
- NCT05472233
- Testing
- Suture removal after Coronally Positioned Flap
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Gingival Recession
Evaluating Coronally Advanced Flap With Platelet-rich Fibrin Membrane and Chorion Membrane for Gingival Recession
The present study was a double-blind, randomised, controlled clinical trial with a parallel design, comparing the coronally advanced flap (CAF) with platelet-rich fibrin (PRF) and chorion membrane (CM) for the treatment of…
- Trial name
- NCT07308405
- Testing
- Coronally advanced flap (CAF) with platelet-rich fibrin (PRF), A similar surgical procedure was followed for the recipient bed preparation similar to that for the PRF membrane. A chorion membrane (Tissue bank, Tata Memorial Hospital, Mumbai, Maharashtra, India) o
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institute of Dental Sciences, Bareilly, Uttar Pradesh, India
Mesial Movement of Teeth
Full Thickness Mucoperiosteal Flap Versus Low Level Laser in Orthodontic Tooth Movement Acceleration
This study aimed to evaluate the effect of using full thickness mucoperiosteal flap (FTMPF) elevation only versus low level laser therapy (LLLT) on acceleration of orthodontic tooth movement.
- Trial name
- NCT04055935
- Testing
- elevation of full thickness mucoperiosteal flap, low level laser therapy
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Asthma
GSK2190915A - Bioavailability Study
GSK2190915 is a high affinity 5-lipoxygenase-activating protein (FLAP) inhibitor that reduces inflammation in cells. This study will evaluate three capsule and two tablet formulations to select the optimal formulation for further…
- Trial name
- NCT02224521
- Testing
- GSK2190915 Solution., GSK2190915 Granule Capsule (A), GSK2190915 Semi-solid Lipid Capsule (B)
- Where
- United Kingdom
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Myopic LASIK Candidates With Spherical Equivalent up to - 10 Diopters
Thin-Flap Laser in Situ Keratomileusis Associated Dry Eye
Laser in situ keratomileusis (LASIK) eye surgery continues to be the most common refractive procedure used to correct different forms of ametropia.
- Trial name
- NCT04831177
- Testing
- Laser in situ keratomileusis
- Where
- Egypt
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gingival Recession, Generalized
Cor Adv Flap Plus Ac Derm Matrix in Thin Phenotype Multiple Recessions
Clinical evaluation of conventional and modified coronally advanced flaps combined with acellular dermal matrix graft
- Trial name
- NCT03883438
- Testing
- Modified coronally advanced flap and acellular dermal matrix graft
- Where
- 4 sites in Azerbaijan, Brazil and 2 more
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Aziz Aliyev Azerbaijan State Advanced Training Institute for Doctors
Gingival Recession
Mucoderm or Connective Tissue Graft for Treatment of Gingival Recessions
Coronally advanced flap plus connective tissue graft (CTG) is the gold standard therapy for root coverage. The bioabsorbable porcine collagen matrix (CM) has been widely used in periodontal and mucogingival surgery as a…
- Trial name
- NCT03675334
- Testing
- Root coverage with collagen matrix graft, Root coverage with subepithelial connective tissue graft, Basic periodontal treatment
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Gingival Recession
Single Stage Root Coverage for Gingival Recession With or Without Free Gingival Graft
Background and Objective: Gingival recession accounts for apical migration of the gingival margin resulting in exposure of the cementoenamel junction (CEJ) and root surface.
- Trial name
- NCT03370042
- Testing
- semilunar coronally positioned flap with free gingival graft, semilunar coronally positioned flap alone
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kamineni Institute of Dental Sciences
Ophthalmopathy
Single Superior ILM/ERM Flap for the FTMH.
In this study, the investigators will make the only upper flap either from the internal limiting membrane or from the epiretinal membrane to cover the full thickness macular hole.
- Trial name
- NCT05494242
- Testing
- Surgical intervention
- Where
- Iraq
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Omer Othman Abdullah
Bone Involvement in Diseases Classified Elsewhere
Influence of Two Different Flap Designs for Sinus Floor Elevation
It is assumed that the reduction of the flap dimension could provide a reduction of surgical time, post surgical complications and patient's discomfort when compared with the traditional surgical approach.
- Trial name
- NCT03272100
- Testing
- flap
- Where
- 2 sites in Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Firenze and Siena, Napoli, Italy