Clinical trials: Flap Disorder
Tympanic Membrane Perforation
Composite Cartilage Perichondrium Graft for Air Bone Gap Closure in Chronic Suppurative Otitis Media (CSOM) Without Posterior Meatal Flap
Composite Cartilage Perichondrium Graft for tympanoplasty in chronic suppurative otitis media (CSOM) Air Bone Gap (AB Gap) Closure will be taken as successful outcome Endoscopic technique without posterior meatal flap elevation
- Trial name
- NCT05086718
- Testing
- Endoscopic ear surgery
- Where
- Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Combined Military Hospital Quetta
Refractive Errors
Corneal Flap Thickness Planed vs Measured After LASIK by Using Tree Different Systems Cut
Determine the flap thickness created by femtosecond laser or a mechanical microkeratome using in vivo confocal microscopy and compare measured versus intended flap thickness.
- Trial name
- NCT00558324
- Testing
- LASIK
- Where
- Mexico
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Asociación para Evitar la Ceguera en México
Chronic Periodontitis
Osteoprotegerin Before and After Periodontal Surgery
The study hypothesis: Is Osteoprotegerin a diagnostic and/or prognostic marker of periodontal disease?
- Trial name
- NCT02160613
- Testing
- Open flap debridement
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Macula Hole
Macular Hole Surgery With Temporal Inverted Internal Limiting Membrane Flap (MARTIAL)
Since 1991, idiopathic macular holes (MH) can benefit from an effective treatment initially involving pars plana vitrectomy, stripping of epiretinal membranes and intraocular gas tamponade followed by facedown positioning.
- Trial name
- MARTIAL (NCT03287102)
- Testing
- Macular hole surgery
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Cleft Palate
Fistiulation Rate Following Primary Cleft Repair≤
Aim : The aim of present study was to evaluate the buccinator flap utilization in primary cleft palatoplasty on fistulation rate.
- Trial name
- NCT05166408
- Testing
- Buccinator myomucosal flap, Bardach two flap palatoplasty
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession, Localized
Tuberosity Versus Palatal Connective Tissue Graft on the Treatment of Single Maxillary Recession-type Defects
The goal of this randomized clinical study is to assess the root coverage outcomes and patient morbidity following the treatment of single maxillary recession-type defects using a coronally advanced flap (CAF) combined with a…
- Trial name
- NCT06404762
- Testing
- tSCTG+ CAF, pSCTG+ CAF
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Chronic Periodontitis
Influence of Gingival Biotype on the Outcome of Open Flap Debridement
The influence of periodontal thickness has been documented in outcome of various periodontal interventions like non surgical periodontal therapy, mucogingival therapy, guided tissue regeneration (GTR), crown lengthening and…
- Trial name
- NCT03882138
- Testing
- open flap debridement
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Myopic LASIK Candidates With Spherical Equivalent up to - 10 Diopters
Thin-Flap Laser in Situ Keratomileusis Associated Dry Eye
Laser in situ keratomileusis (LASIK) eye surgery continues to be the most common refractive procedure used to correct different forms of ametropia.
- Trial name
- NCT04831177
- Testing
- Laser in situ keratomileusis
- Where
- Egypt
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gingival Recession, Localized
L-PRF Versus Connective Tissue Graft Associated to Coronally Advanced Flap in Gingival Recession Treatment
Background: Nowadays, the use of connective tissue graft associated to the coronally advanced flap is considered the "gold standard" for localized gingival recession treatment.
- Trial name
- NCT04165044
- Testing
- Leukocyte and Platelet Rich Fibrin plus Coronally Advanced Flap, Connective tissue graft plus Coronally Advanced Flap
- Where
- Chile
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Atrophy of Gingiva
Volumetric Evaluation of Gingival Augmentation Around Dental Implants
The goal of this observational prospective study is to objectively assess the dimensional (volume \& linear variance) and clinical changes of vestibular gingival soft tissues upon treatment with laser-aided pouch roll…
- Trial name
- NCT06057363
- Testing
- volumetric evaluation of gingival augmentation around dental implants
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Odontostomatologic Laser Therapy Center, Florence, Italy
Dental Implant, Tooth Loss
Flap Vs Flapless Technique for Delayed Implant Placement in the Maxillary Esthetic Zone
This randomized comparative clinical trial aims to evaluate the clinical, radiographic, and esthetic outcomes of flap versus flapless techniques for delayed dental implant placement in the maxillary esthetic zone.
- Conditions
- Dental Implant, Tooth Loss, Partial Edentulism, Maxillary Tooth Loss
- Trial name
- NCT07654452
- Testing
- Flap Implant Placement, Flapless Implant Placement
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Jaw, Edentulous, Partially
Ridge Preservation Comparing the Clinical and Histologic Healing of Flap vs. Flapless Approach to Grafting
Ridge Preservation Comparing the Clinical and Histologic Healing of Flap vs. Flapless Approach to Grafting
- Trial name
- NCT02487758
- Testing
- Ridge Preservation
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Growth Factors, Combined Defect of, Gingival Recession
Growth Factors in the Treatment of the Multiple Gingival Recessions
The purpose of this study was to compare and evaluate the clinical effects of Concentrated Growth Factor (CGF) and Advanced Platelet-Rich Fibrin (A-PRF) applied together with Coronally Advanced Flap (CAF) technique using a…
- Trial name
- NCT05319938
- Testing
- CAF only, CAF+CGF, CAF+A-PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Myopia, Hyperopia
Creating LASIK Flaps With the LenSx Femtosecond Laser
This will be a prospective, single-center clinical trial of up to 50 eyes of subjects scheduled to undergo LASIK surgery requiring an initial corneal flap. Subjects will be screened for eligibility.
- Trial name
- NCT01556893
- Testing
- LenSx Laser
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alcon LenSx, Inc.
Impacted Third Molar Tooth
Comparison of Two Different Flap Designs for Bilateral Impacted Mandibular Third Molar Surgery
The aim of this study was to compare the effects of lingually-based triangle flap design and buccally based triangular flap design on postoperative swelling, trismus pain after mandibular third molar surgery.
- Trial name
- NCT03784638
- Testing
- lingually-based triangle flap design, buccally based triangular flap design
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Furcation Defects, Open Flap Debridement
Evaluation of Outcomes of Minimally Invasive Non- Surgical Versus Surgical Therapy in Furcation Involvement.
The reduced rate of success experienced in the treatment of Furcation involvement (FI) seems to result from the incomplete removal of subgingival plaque and calculus in the interradicular area owing to the peculiar anatomy of the…
- Conditions
- Furcation Defects, Open Flap Debridement, Periodontal Diseases
- Trial name
- NCT06025955
- Testing
- minimally invasive non- surgical therapy, open flap debridement
- Where
- India
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Asthma
GSK2190915A - Bioavailability Study
GSK2190915 is a high affinity 5-lipoxygenase-activating protein (FLAP) inhibitor that reduces inflammation in cells. This study will evaluate three capsule and two tablet formulations to select the optimal formulation for further…
- Trial name
- NCT02224521
- Testing
- GSK2190915 Solution., GSK2190915 Granule Capsule (A), GSK2190915 Semi-solid Lipid Capsule (B)
- Where
- United Kingdom
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Gingival Recession
Evaluation of Root Coverage After the Use of Coronally Advanced Flap Either With Advanced Paltelet Rich Fibrin or Subepithilial Connective Tissue Graft in Treatment of Miller Class I and II Gingival Recession.
patients with Miller class I , II gingival recession will be divided into 2 groups (control, intervention).the control one will receive coronally advanced flap with subepithililal connective tissue graft harvested from the palate…
- Trial name
- NCT03695549
- Testing
- CAF + (A-PRF), CAF+SCTG
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Nasoalveolar Fistula (Defect)
Clinical Assessment of Usage of Cleft Margin Flap With Anterior Palatal Closure in Closure of Naso-alveolar Defect.
During primary cleft lip repair in patients who were born with cleft lip and palate, usage of cleft margin flap with anterior palatal closure will be done in an attempt to close the Naso-alveolar fistula (defect) that usually…
- Trial name
- NCT03922438
- Testing
- usage of cleft margin flap with anterior palatal closure during primary cleft lip repair.
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession, Recession, Gingival
Coronally Advanced Flap With Alloderm Versus Coronally Advanced Flap With Micro-needling on RT1 Gingival Recession
This study aims to assess the effect of micro-needling together with coronally advanced flap procedure on the gain of gingival thickness (GT) and keratinized tissue width (KTW) and compare it to Alloderm with coronally advanced…
- Conditions
- Gingival Recession, Recession, Gingival, Thin-gingiva
- Trial name
- NCT05470660
- Testing
- Root coverage using coronally advanced flap combined with micro-needling, coronally advanced flap combined with Alloderm
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University