Clinical trials: Flexibility
Asthma
Flexibility and Strength Training in Asthma
The aim of the study is proof of concept and to establish the feasibility of performing a study of resistive flexibility and strength training (RFST) in patients with asthma, with the future goal of designing a larger randomized…
- Trial name
- FASTA (NCT02370004)
- Testing
- Resistive Flexibility and Strength Training
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Brigham and Women's Hospital
Languages
Impact of Theta Burst Stimulation Over the Left DLPFC on Language Switching
The purpose of this study is to investigate whether theta burst stimulation (TBS) over the left dorsolateral prefrontal cortex (DLPFC) influences language switching and cognitive flexibility.
- Trial name
- NCT03148470
- Testing
- intermittent theta burst stimulation (iTBS), continuous theta burst stimulation (cTBS)
- Where
- Switzerland
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Jean-Marie Annoni
Diabetes Mellitus, Type 2
Novel Approach to Assess Metabolic Flexibility in a Respiratory Chamber
The overarching aim of this study: To determine the effect of different meal compositions (high- vs. low-fat) on metabolic flexibility as it relates to meal-stimulated change in respiratory quotient (ΔRQ1) and sleep (ΔRQ2)…
- Trial name
- METFLEX (NCT03839641)
- Testing
- High fat meal, Low fat meal
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Parkinson's Disease With Dementia
The Impact of Pharmacological and Electric Modulation of NMDA Pathway on the Cognitive Flexibility and Volitional Movement Preparation in Patients With Parkinson's Disease
The project will investigate the effect of pharmacological and electric modulation of N-methyl-D-aspartate (NMDA) pathway on the cognitive flexibility and volitional movement preparation in patients with Parkinson's disease (PD).
- Trial name
- NCT01785628
- Testing
- Sarcosine Capsule
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- China Medical University Hospital
Hamstring Injury, Muscle Tone Increased
Cranial Laser Reflex Technique for Hamstring Function
Purpose: To conduct a pilot study of the effect of Cranial Laser Reflex Technique (CLRT) compared with sham laser on hamstring muscle flexibility, strength, and pain pressure threshold.
- Conditions
- Hamstring Injury, Muscle Tone Increased, Muscle Pain, Muscle Weakness
- Trial name
- CLRTHam (NCT03044106)
- Testing
- CLRT
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Healthy Cognition
Exercise for Brain Health in the Fight Against Alzheimer's Disease
The investigators aim to compare the effects of a 6-month moderate intensity exercise training (ET) intervention to a low intensity flexibility exercise control condition (FC) on brain function, cognition, and physical function…
- Trial name
- NCT03727360
- Testing
- Exercise Training, Flexibility Control
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Atopic Dermatitis
A Study to Assess Treat-to-Target and Dosing Flexibility of Oral Upadacitinib Tablets in Adult Participants With Moderate to Severe Atopic Dermatitis
Atopic dermatitis (AD) is a skin condition that may cause a rash and itching due to inflammation of the skin. Therapies spread over the skin may not be enough to control the AD in trial participants who require systemic…
- Trial name
- Flex-Up (NCT05507580)
- Testing
- Upadacitinib
- Where
- 106 sites in Australia, Belgium and 16 more
- Volunteers
- 461 people
- Sponsor
- AbbVie
Alcohol Abuse, Cognitive Deficit in Attention
Pilot Study on Training Emerging Adults Skills in Navigating College
Lifetime risk for developing an alcohol use disorder increases with earlier onset of alcohol consumption. This risk may reflect a tendency for escalated alcohol intake among youth due to immature executive control, leading to…
- Trial name
- SINC (NCT05560425)
- Testing
- Koru Mindfulness (KM) Training, Navigating College (NC) Training
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Stroke
Strength, Flexibility, And Balance Therapy After Stroke
Approximately 780,000 people suffer a stroke annually in the United States; 200,000 are recurrent strokes. The 17,000 veterans who suffer a stroke yearly are at great risk for a second stroke and therefore should be targeted for…
- Trial name
- HEALTHY (NCT01109602)
- Testing
- Yoga focused on strength, flexibility, and balance
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- VA Office of Research and Development
Type 1 Diabetes
The Influence of Glycemic Control and Obesity on Energy Balance and Metabolic Flexibility in Type 1 Diabetes
The purpose of this study is to measure the metabolic phenotype of a range of body weights in individuals with and without type 1 diabetes.
- Trial name
- ACME (NCT03379792)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Rheumatoid Arthritis
Open Label Extension for Patients Coming From the Dosing Flexibility Study in Patients With Rheumatoid Arthritis (RA)
The purpose of this study is to continue to assess the safety of certolizumab pegol in combination with methotrexate (MTX).
- Trial name
- Dose Flex II (NCT00753454)
- Testing
- Certolizumab pegol
- Where
- 40 sites in United States, Canada
- Volunteers
- 168 people
- Sponsor
- UCB Pharma
Chronic Pain
Mindful Action for Pain
An emerging scientific model that has been applied to chronic pain is the psychological flexibility (PF) model. PF refers to the ability to behave consistently with one's values even in the face of unwanted thoughts, feelings…
- Trial name
- MAP (NCT03800654)
- Testing
- Mindful Action for Pain, Cognitive Behavioral Therapy for Chronic Pain
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- VA Office of Research and Development
Executive Function
The Effect of Acute Concurrent Exercise on Executive Function: An Event-Related Potential Study
Executive function is a high-level cognition which plays an important role in our life. Meta-analysis study has demonstrated that acute exercise could improve executive function.
- Trial name
- NCT05314634
- Testing
- concurrent exercise, aerobic exercise
- Where
- Taiwan
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Substance Use Disorders
Guanfacine to Improve Substance Use Outcomes in Women
Hypothesis: Guanfacine (GUA) (3mg/day) will reduce drug craving, improve cognitive flexibility and result in associated lower drug use in women with substance use disorder (SUD) in an outpatient clinical setting.
- Trial name
- NCT03980184
- Testing
- Guanfacine, Behavioral Counseling
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Yale University
Diabetes, Diabetes Mellitus, Type 1
Comparison of NN1250 With Insulin Glargine in Type 1 Diabetes
This trial is conducted in Europe and in the United States of America (USA). The aim of this trial is to investigate the efficacy and safety of NN1250 (insulin degludec) in subjects with type 1 diabetes.
- Trial name
- BEGIN™ (NCT01079234)
- Testing
- insulin degludec, insulin glargine, insulin aspart
- Where
- 82 sites in United States, Belgium and 5 more
- Volunteers
- 493 people
- Sponsor
- Novo Nordisk A/S
Cerebral Palsy, Developmental Delay
Endermotherapy for Children With Developmental Disabilities
Children with developmental disabilities often sustain decreased range of motion in their extremities. The decrease in flexibility may be due to neuromuscular disorders such as spasticity or dystonia.
- Trial name
- NCT01207570
- Testing
- Endermotherapy, Passive manual stretching
- Where
- Hong Kong
- Volunteers
- 54 people
- Sponsor
- The Hong Kong Polytechnic University
Rheumatoid Arthritis
Dosing Flexibility Study in Patients With Rheumatoid Arthritis
During the run-in period, CZP will be administered at 400 mg (2 injections) at Wks 0, 2, and 4 and 200 mg with placebo (1 injection placebo, 1 injection CZP) at Wks 6, 8, 10, 12, 14 and 16.
- Trial name
- DoseFlex (NCT00580840)
- Testing
- Certolizumab pegol
- Where
- 66 sites in United States, Canada and 1 more
- Volunteers
- 333 people
- Sponsor
- UCB Pharma
PTSD, Depression
Impact of Modifiable Psychosocial Factors on Veterans' Long-term Trajectories of Functioning and Quality of Life
This study is Phase 3 of Project SERVE (Study Evaluating Returning Veterans' Experiences). Through two prior phases, SERVE has followed a cohort of post-9/11 Veterans since 2010 and has identified numerous risk and protective…
- Conditions
- PTSD, Depression, Chronic Pain, Alcohol Use Disorder
- Trial name
- SERVE:IMPACT (NCT03615222)
- Where
- 2 sites in United States
- Volunteers
- 377 people
- Sponsor
- VA Office of Research and Development
Eating Disorders, Body Image
FlexED: A Digital, Gamified Early Intervention for Eating Disorders
The goal of this clinical trial is to test a new intervention for body-image distress to reduce eating disorder symptoms in young women and girls between the ages of 15-25 years old.
- Trial name
- NCT05609409
- Testing
- FlexED
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Duke University
Low Back Pain
A Prospective Pilot Study Investigating the Impact of ThermaCare on Flexibility, Muscle Relaxation & Low Back Pain
The objective of this Investigator Initiated study is to evaluate the effectiveness of ThermaCare HeatWraps in improving flexibility and low back muscle relaxation, and in participants experiencing pain, reducing pain during…
- Trial name
- NCT03151265
- Testing
- ThermaCare Low Back Heat Wrap
- Where
- 3 sites in Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- dorsaVi Ltd