Clinical trials: Flexion Deformity, Knee
Knee Deformity
Correction of Fixed Knee Flexion Deformity in Children Using Eight-plate Hemiepiphysiodesis
The study aims to assess the effectiveness of hemiephysiodesis using eight plates in correction of fixed knee flexion deformities in children.
- Trial name
- NCT03689959
- Testing
- Eight plate hemiepiphysiodesis
- Where
- Egypt
- Volunteers
- 23 people
- Sponsor
- Assiut University
Flexion Deformity of Knee
Correction of Fixed Knee Flexion Deformity in Children Distraction by Cast Wedge and Rod Lengthening
The aim of our study is to produce gradual correction of FKFD in younger children.
- Trial name
- NCT04911686
- Testing
- rod distraction
- Volunteers
- 20 people
- Sponsor
- Assiut University
Osteo Arthritis Knee
Utilization of a Knee Brace With Extension Swing
The purpose of this research is to help determine if use of the Guardian brace during prehab and post-op rehab after TKA can help improve functional outcomes and reduce the incidence of post-operative flexion contractures which…
- Trial name
- NCT05179044
- Testing
- Guardian Sport Rehabilitator knee brace
- Where
- United States
- Sponsor
- NYU Langone Health
Osteoarthritis, Traumatic Arthritis
Prospective Multicenter Post Approval Study of the LPS-Flex Mobile Bearing Knee
The purpose of the study is to assess the long-term performance of the NexGen LPS-Flex Mobile Bearing Knee in the treatment of patients with severe knee pain or degenerative knee disease.
- Conditions
- Osteoarthritis, Traumatic Arthritis, Avascular Necrosis of the Femoral Condyle, Moderate Varus
- Trial name
- NCT00854295
- Testing
- NexGen LPS-Flex Mobile Bearing Knee
- Where
- 3 sites in United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Knee Osteoarthritis
Short-term and Intermediate-term Effects of Self-applied Joint Mobilization Versus Clinician-applied Joint Mobilization in Addition to Exercise in Patients With Knee Osteoarthritis: A Randomized Clinical Trial
The goal of this clinical trial is to learn if a combination of patient self-administered joint mobilization and exercise works to treat knee osteoarthritis in adults.
- Trial name
- NCT07020897
- Testing
- Clinician-administered joint mobilization, Self-administered joint mobilization, Exercise-based physical therapy
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Texas Woman's University
Knee Pain Chronic, Osteoarthritis, Knee
Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)
The main objective of the study is to evaluate the safety, performance and clinical benefits of the Persona implant and its instrumentation in primary total knee arthroplasty
- Conditions
- Knee Pain Chronic, Osteoarthritis, Knee, Rheumatoid Arthritis, Traumatic Arthritis
- Trial name
- NCT05787821
- Testing
- Total Knee Arthroplasty
- Where
- 16 sites in United States
- Volunteers
- 760 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee, Rheumatoid Arthritis
A Comparison of Two Surgical Techniques Using the Unity Knee™ Total Knee System
A comparison of two Unity Knee™ tissue-balancing techniques by analysing the results from X-rays and patient questionnaires.
- Conditions
- Osteoarthritis, Knee, Rheumatoid Arthritis, Post-Traumatic Osteoarthritis of Knee, Varus Deformity, Not Elsewhere Classified, Knee
- Trial name
- NCT03511144
- Testing
- Unity Knee™ TKR using measured resection, Unity Knee™ TKR using ligament balancing
- Sponsor
- Corin
Knee Pain, Chronic Osteoarthritis
ROSA Robot Used in Total Knee Replacement Post Market Study
This is a prospective, multicenter clinical study designed to facilitate the collection and evaluation of workflow efficiency, patient pain and function, and adverse event data.
- Conditions
- Knee Pain, Chronic Osteoarthritis, Avascular Necrosis of the Femoral Condyle, Moderate Varus, Valgus or Flexion Deformities
- Trial name
- NCT03969654
- Testing
- PERSONA Total Knee, Vanguard Total Knee, NexGen Total Knee
- Where
- 5 sites in United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Acquired Fixed Flexion Deformity of the Knee (Disorder)
Effects of Dynamic Splinting on Knee Flexion Angle After Total Knee Arthroplasty: A Randomized Controlled Trial
To evaluate the effects of a knee flexion Dynasplint orthosis on knee flexion angle after a total knee arthroplasty. Sixty participants, who underwent a total knee arthroplasty, were randomly assigned in two groups: control group…
- Trial name
- NCT02928835
- Testing
- Knee flexion Dynasplint orthosis
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Universidade Norte do Paraná
Knee Pain, Chronic Osteoarthritis
ROSA Total Knee Investigational Testing Authorization Study
This is a prospective, single-center clinical study designed to facilitate the collection and evaluation of workflow efficiency, patient pain and function, and adverse event data.
- Conditions
- Knee Pain, Chronic Osteoarthritis, Avascular Necrosis of Femoral Condyle, Moderate Varus, Valgus or Flexion Deformities
- Trial name
- NCT03970629
- Testing
- PERSONA Total Knee
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Flexion Contracture Following Total Knee Replacement
Botulinum Toxin A to Treat Flexion Contracture After Total Knee Arthroplasty
The goal of this research project is to evaluate injections of botulinum toxin A (Botox) as the treatment for knee flexion contracture after total knee arthroplasty (TKA).
- Trial name
- NCT01829087
- Testing
- Botox
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- Rothman Institute Orthopaedics
Knee Osteoarthritis, Flexion Contracture of Knees
IPICK Blocking for TKA With Moderate Flexion Contracture
Clinical effect of intermittent multiple IPICK blocking on TKA for knee osteoarthritis with flexion contracture between 5 ° and 10 °
- Conditions
- Knee Osteoarthritis, Flexion Contracture of Knees, Anesthesia, Local
- Trial name
- NCT04603950
- Testing
- CACB+IPACK, CACB
- Where
- China
- Volunteers
- 42 people
- Sponsor
- The First Hospital of Jilin University
Knee Pain, Chronic Osteoarthritis
ROSA Total Knee Post Market Study EMEA
This is a prospective, multicenter clinical study designed to facilitate the collection and evaluation of surgical workflow efficiency, patient pain and function outcome and adverse events data.
- Conditions
- Knee Pain, Chronic Osteoarthritis, Avascular Necrosis of the Femoral Condyle, Moderate Varus, Valgus or Flexion Deformities
- Trial name
- NCT04338893
- Testing
- Device: Persona Total Knee, Device: NexGen Total Knee, Device: Vanguard Total Knee
- Where
- 6 sites in Belgium, Germany and 3 more
- Volunteers
- 252 people
- Sponsor
- Zimmer Biomet
Flexion Contracture
Effectiveness of KneeMD on Flexion Contracture in Total Knee Arthroplasty Patients
The purpose of this study is to evaluate the effect of the KneeMD subject-controlled knee rehabilitation device on the incidence of postoperative flexion contracture.
- Trial name
- KneeMD (NCT02638480)
- Testing
- KneeMD
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Anne Arundel Health System Research Institute
Knee Pain Chronic, Osteoarthritis
Persona Total Knee Arthroplasty Outcomes Study
The primary objective of this study is to obtain implant survivorship and clinical outcomes data for commercially available Persona fixed bearing knee implants used in total knee arthroplasty.
- Conditions
- Knee Pain Chronic, Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis
- Trial name
- NCT02255383
- Testing
- Zimmer Persona Total Knee System
- Where
- 14 sites in United States
- Volunteers
- 737 people
- Sponsor
- Zimmer Biomet
Knee Pain Chronic, Rheumatoid Arthritis
Cemented vs Cementless Persona Keel RCT
The main objective of this study is to evaluate the safety, performance, and clinical benefits of the Persona Keel cementless and cemented knee.
- Conditions
- Knee Pain Chronic, Rheumatoid Arthritis, Osteoarthritis, Traumatic Arthritis
- Trial name
- NCT05630053
- Testing
- Cementless Persona Knee System, Cemented Persona Knee System
- Where
- 7 sites in United States
- Volunteers
- 300 people
- Sponsor
- Zimmer Biomet
Knee Flexion Contracture, Total Knee Arthroplasty (TKA)
Anterior Heel Wedge to Treat Flexion Contracture After Total Knee Arthroplasty
Total knee arthroplasty (TKA) remains the only treatment for end-stage knee osteoarthritis, whereby the diseased ends of the bones comprising the knee joint are removed and replaced with prosthetic joint components.
- Trial name
- NCT07620145
- Testing
- Anterior heel wedge
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of North Carolina, Charlotte
Osteoarthritis, Contracture
Reducing Recurrent Knee Flexion Contracture by Correcting Leg Length Discrepancy After Total Knee Arthroplasty for OA
Moving one's joints through their full range of motion (ROM) is crucial for health and wellbeing. Those who are unable to do so have difficulty carrying out simple activities like walking or feeding themselves.
- Trial name
- NCT02861521
- Testing
- Shoe lift
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- Ottawa Hospital Research Institute
Transient Tachypnea of the Newborn
Reducing Respiratory Distress After Elective Caesarean Birth Through Knee-chest-flexion: a Randomized Controlled Trial
Planned caesarean birth is a risk factor for the development of neonatal respiratory distress commonly known as transient tachypnoea of the newborn.
- Trial name
- NCT06270823
- Testing
- Knee-to-chest-flexion manoeuvre
- Where
- Tanzania
- Volunteers
- 562 people
- Sponsor
- Kilimanjaro Clinical Research Institute
Rhematoid Arthritis, Osteo Arthritis of the Knee
Persona SoluTion PPS Femur PMCF
The goal of this study is to generate clinical evidence and evaluate the safety and performance of the Persona® SoluTion® PPS Femurs in the US market, with data supporting global regulatory submissions, including CE marking under…
- Conditions
- Rhematoid Arthritis, Osteo Arthritis of the Knee, Traumatic Arthritis of Knee (Diagnosis), Polyarthritis
- Trial name
- NCT07286513
- Testing
- Total knee arthroplasty
- Where
- 5 sites in United States
- Volunteers
- 200 people
- Sponsor
- Zimmer Biomet