Clinical trials: Fluid Output
Anesthesia
Automated Administration of Fluids Guided by Dynamic Parameters and Cardiac Output During General Anesthesia
The main objective of this study is to demonstrate that the LIR (Learning Intravenous Resuscitator) Closed-Loop Fluid Administration System (hereafter the "LIR system"), a new device for the automated administration of…
- Trial name
- Closed Loop (NCT02138942)
- Testing
- Learning Intravenous Resuscitator (LIR) system
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
AKI - Acute Kidney Injury, Cardiac Surgery
Urine Output Response to Fluid and Diuretic Therapy in Cardiac ICU Patients Monitored With FIZE kUO®
This prospective observational study evaluates the real-time urine output response to fluid therapy and diuretics in cardiothoracic intensive care unit (CTICU) patients monitored with the FIZE kUO® device.
- Conditions
- AKI - Acute Kidney Injury, Cardiac Surgery, Fluid Therapy, Hemodynamic Instability
- Trial name
- NCT07022314
- Testing
- FIZE kUO®
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- FIZE Medical ltd
Cardiogenic Shock
Passive Leg Raising for Predicting Fluid Responsiveness in VA-ECMO Assisted Patients
Peripheral Veno-Arterial Extra Corporeal Membrane Oxygenation (VA ECMO) is a temporary assistance that provides a mechanical circulatory support in patients victim of cardiogenic shock (CS) or refractory cardiac arrest.
- Trial name
- PARANOVA (NCT04984603)
- Testing
- PLR in patients under VA-ECMO
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
VCO2 Variation in Intensive Care as a Marker of Fluid Responsiveness, Cardiac Index Variation Transpulmonary Thermodilution in Patients on Controlled Ventilation With Shock
Cardiac Responsiveness Assessment by CO2
The increase of cardiac output resulting from increased blood volume (systolic ejection volume) during intravenous fluid administration defines a state of fluid responsiveness.
- Trial name
- CRAC (NCT05430880)
- Testing
- impact of fluid challenge on the cardiac index and CO2 respiratory parameters analysis (VCO2, EtCO2)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Hip Fractures
Non Invasive Cardiac Output Monitoring to Guide Goal Directed Fluid Therapy in High Risk Patients Undergoing Urgent Surgical Repair of Proximal Femoral Fractures
Improving or maximising cardiac output in the perioperative setting through the use of goal directed fluid therapy has been shown to reduce complications and length of hospital stay in patients undergoing major abdominal surgery.
- Trial name
- ClearNOF (NCT02382185)
- Testing
- Fluid optimisation, Optimisation of blood pressure, Application of clearsight monitor
- Where
- 2 sites in United Kingdom
- Volunteers
- 240 people
- Sponsor
- York Teaching Hospitals NHS Foundation Trust
Shock
Evaluation of the Argos System to Estimate Cardiac Output
The goal of this observational study is to evaluate the reliability of the Argos system to track changes in cardiac output in critically ill patients.
- Trial name
- NCT07724262
- Testing
- Fluid bolus, Norepinephrine
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Bicetre Hospital
Cardiac Output, High
Mean Systemic Filling Pressure and Heart Performance Predicting Fluid Responsiveness in Sepsis
The purpose of this study is to determine fluid responsiveness in critically ill patients by measuring mean systemic filling pressure on the intensive care unit.
- Trial name
- NCT02778633
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Hypotension, Shock
Brachial Artery Peak Velocity Variation to Predict Fluid Responsiveness
The investigators designed this study to determine the predictive value for predicting fluid responsiveness of noninvasive evaluation of respiratory variation of peak velocity in brachial artery, in mechanically ventilated…
- Trial name
- NCT00890071
- Testing
- Fluid administration
- Where
- Spain
- Volunteers
- 38 people
- Sponsor
- Hospital del SAS de Jerez
Arterial Hypotension
Effect of Phenylephrine Versus Norepinephrine on Venous Return
Induction of general anesthesia often induces a decrease in the mean arterial blood pressure (MAP) caused by arterial and venous dilatation.
- Trial name
- NCT03872570
- Testing
- Phenylephrine, Norepinephrine
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Hypovolemic Shock
Hemodynamic Measurements at Different Inclinations of the Head
The purpose of this study is to determine whether hemodynamic measures vary in angles bedside before and after volume challenge.
- Trial name
- HMDIH (NCT02046785)
- Testing
- 0.9% saline solution
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of Uberlandia
Hypovolemia, Impaired Oxygen Delivery
Observational Study of Oxygen Delivery During a Fractional Fluid Expansion
Fluid expansion during cardiocirculatory insufficiency was helped by cardiac output monitoring. However, the goal of fluid expansion was to increase the oxygen delivery, which consider cardiac output, but also Haemoglobin which…
- Conditions
- Hypovolemia, Impaired Oxygen Delivery, Cardiac Output, Low
- Trial name
- OR (NCT01826253)
- Testing
- hydroxyethylstarch 130/0.4
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Caen
Intravenous Fluids, Pharmacodynamics
Effect of Oral Water in Healthy Volunteers on Cardiac Output, Regional Flow and Microcirculation in Healthy Volunteers
Human digestive system physiologically ensures the absorption of oral water and hydration of the human body. Water is quickly absorbed by the digestive tract with a peak between 15 and 20 minutes.
- Conditions
- Intravenous Fluids, Pharmacodynamics, Fluid Therapy, Fluid Responsiveness
- Trial name
- WATERNAL (NCT05153837)
- Testing
- saline intravenous administration, oral water
- Where
- France
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Hypotension
Hemodynamic Optimization By Non-Invasive Determination Of Cardiac Output In Critically Ill Patients
Inadequate identification of and subsequent delayed therapy for patients with hypoperfusion (including hypovolemia, congestive heart failure and sepsis) is a common problem faced by physicians and intensivists caring for…
- Trial name
- NCT01309724
- Testing
- USCOM-guided fluid administration
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Washington University School of Medicine
Acute Kidney Injury, Critical Illness
Definition of Acute Kidney Injury by Urine Output in Critically Ill Patients
The goal of this observational study is to explore the association between urine output and acute kidney injury in severely ill patients admitted to intensive care units.
- Conditions
- Acute Kidney Injury, Critical Illness, Critical Care, Intensive Care, Critical Care, Fluid Resuscitation
- Trial name
- NCT06722924
- Volunteers
- 15,000 people
- Sponsor
- Uppsala University
Cardiac Output, Low, Cardiac Output, High
Use of a Mini-fluid Bolus to Identify Fluid Responsiveness
On the Intensive Care Unit doctors give a lot of fluid to patients in order to improve their blood pressure, amount of urine made or to let doctors stop drugs that are needed to keep blood pressure up.
- Trial name
- NCT03058653
- Testing
- Small fluid boluses of 50 ml, LIDCORapid Monitor
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Septic Shock, Hemodynamic Instability
Whether a Minimal Volume Could Predict Fluid Responsiveness Using Thermodilution by PAC in Septic Shock Patients
Assessment of fluid responsiveness (FR) is to detect whether patient could benefit from fluid therapy. Mini fluid challenge has been widely used in clinical practice to prevent patients from volume overload.
- Conditions
- Septic Shock, Hemodynamic Instability, Fluid Therapy
- Trial name
- NCT04515511
- Testing
- 4% gelatin
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking Union Medical College Hospital
Cardiac Output, High
Mean Systemic Filling Pressure and Heart Performance Predicting Fluid Responsiveness in Aortic Valve Replacement
The purpose of this study is to determine fluid responsiveness in critically ill patients by measuring mean systemic filling pressure on the intensive care unit.
- Trial name
- NCT02778620
- Where
- Netherlands
- Volunteers
- 27 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Sepsis
Non-invasive Measurement of CO in Patients With Uncomplicated Sepsis
Little is known about the optimal fluid therapy of patients with uncomplicated sepsis. Most recommendations are extrapolated from studies performed in patients with septic shock.
- Trial name
- NCT03728998
- Testing
- Passive leg raise (PLR), Clearsight non-invasive hemodynamic monitoring system
- Where
- Netherlands
- Volunteers
- 31 people
- Sponsor
- Frisius Medisch Centrum
Artificial Heart Device User
Impact of Fluid and Passive Leg Raising on Cardiac Output in Patients Undergoing Cardiac Surgery
Left Ventricular Assist Device (LVAD) implantation is a common surgical procedure in patients with end-stage heart failure. Optimal fluid management is essential for adequate postoperative treatment.
- Trial name
- NCT03179033
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Obstetric Anesthesia, Spinal Anesthesia
ED50 Determination of Hydroxyethylstarch for Treatment of Hypotension During Cesarean Section Under Spinal Anesthesia
The purpose of this trial is to determine the effective volume of hydroxyethylstarch 130/0.4 which would prevent the occurence of maternal hypotension in 50% of healthy pregnant women undergoing a cesarean section under spinal…
- Conditions
- Obstetric Anesthesia, Spinal Anesthesia, Hypotension, Fluid Therapy
- Trial name
- NCT01415284
- Testing
- Hydroxyethylstarch 130/0.4
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Maisonneuve-Rosemont Hospital