Clinical trials: Fluid Responsiveness
Central Venous Pressure and Inferior Vena Cava Distensibility Index in Assessing Fluid Responsiveness in Septic Shocked Patients
Central Venous Pressure Versus Inferior Vena Cava Distensibility Index in Assessing Fluid Responsiveness in Septic Shocked Patients
This study aims to compare ultrasound-guided inferior vena cava distensibility index(IVC_DI) assessment with central venous pressure (CVP) monitoring for the detection of hypovolemia in septic shocked patients in the emergency…
- Trial name
- NCT07279064
- Testing
- Ultrasound guided inferior vena cava distensibility index
- Volunteers
- 70 people
- Sponsor
- Assiut University
Stroke Volume Variation
Effect of Wide Pulse Pressure on the Predictability of Stroke Volume Variation for Fluid Responsiveness in Patients Undergoing Off-pump Coronary Artery Bypass Graft
The investigators examined the predictability of stroke volume variation for fluid responsiveness in patients with wide pulse pressure undergoing off-pump coronary artery bypass graft
- Trial name
- NCT01404455
- Testing
- HES 130/0.4 (VoluvenⓇ, Fresenius Kabi, Graz, Austria) 500mL loading
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Severance Hospital
Sepsis
Non-invasive Measurement of CO in Patients With Uncomplicated Sepsis
Little is known about the optimal fluid therapy of patients with uncomplicated sepsis. Most recommendations are extrapolated from studies performed in patients with septic shock.
- Trial name
- NCT03728998
- Testing
- Passive leg raise (PLR), Clearsight non-invasive hemodynamic monitoring system
- Where
- Netherlands
- Volunteers
- 31 people
- Sponsor
- Frisius Medisch Centrum
Hemodynamic Instability, General Anesthesia
End-eXpiratory Occlusion Test to Predict fluId REsponsiveness in the Operating Room (EXPIRE)
The purpose of the study is to evaluate the influence of different durations of the end-expiratory occlusion test to predict fluid responsiveness in mechanically ventilated patients in the operating room.
- Conditions
- Hemodynamic Instability, General Anesthesia, Surgery, Protective Mechanical Ventilation
- Trial name
- EXPIRE (NCT04399278)
- Testing
- Diagnostic Test: end-expiratory occlusion (EEO) test
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hypovolemia
Fluid Responsiveness Using Forehead Sensor in Children
Forehead sensor can predict the more accurate fluid responsiveness than finger sensor in children
- Trial name
- forehead (NCT03132480)
- Testing
- fluid resuscitation
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Prevention of Hypotension
Point Of Care Ultrasound For Prediction Of Fluid Responsiveness in Off Pump Coronary Artery Bypass Grafting Surgery
To exclude hypovolemia before starting off pump coronary artery grafting surgeries by an efficient and good predictive test. We will assess the sensitivity and specificity of dynamic IVC-derived parameters (dispensability index)…
- Trial name
- NCT05968040
- Testing
- Inferior vena cava diameter measurement by ultrasonography, difference between peak velocities of carotid artery by ultrasound, cardiac output be transthoracic echocardiography
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Body Fluid Retention, Impedance
Effect of Passive Leg Raising for Fluid Responsiveness
Changes in volumetric hemodynamic parameters and fluid overload (Cardiac Index,Stroke Volume, Thoracic Fluid Content, Systemic Vascular Resistance) were measured using a impedance cardiography (ICG) (CardioScreen 1000 …
- Conditions
- Body Fluid Retention, Impedance, Cardiac Output, Low
- Trial name
- NCT02702544
- Testing
- CardioScreen 1000 - Haemodynamic Measurement System, Medis, SCHILLER, BR-102 plus - Ambulatory Blood Pressure Monitoring System
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Fluid Therapy, Cardiac Surgical Procedures
Internal Jugular Vein Ultrasound Measures and Fluid Responsiveness in Post-Operative Cardiac Surgical Patients
The goal of this study is to evaluate whether measures of the size of the internal jugular vein have clinical utility in predicting whether patients may benefit from treatment with intravenous fluid.
- Trial name
- NCT00500981
- Testing
- Volume challenge, Ultrasound evaluation of internal jugular vein
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Fluid Responsiveness Predictability
Hemodynamic Response to the End-expiratory Occlusion Test to Titrate Fluid Challenge in Operating Room.
Personalzing intraoperative anesthetic fluid management may help in preventing fluid accumulation and related complications. Fluids are gine as boluses in operating room (the so-called FC).
- Trial name
- FC_EEOT (NCT06627907)
- Testing
- fluid challenge, end-expiratory occlusion test
- Volunteers
- 300 people
- Sponsor
- Humanitas Clinical and Research Center
Shock, Sepsis
Hemodynamic Evaluation of Preload Responsiveness in Children by Using PiCCO
The purpose of this study is To assess the value of dynamics (SVV, PPV) and static indices (GEDVI, ITBVI, CVP) of preload and its combination with contractility (CI,SV, ventricular power, dP/dtmax, CFI, GEF) and lung water…
- Conditions
- Shock, Sepsis, Systemic Inflammatory Response Syndrome, Low Cardiac Output
- Trial name
- PreloaDren (NCT01157299)
- Where
- 7 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitario La Paz
Fluid Responsiveness
Pressure Gradient for Venous Return in Predicting Fluid Responsiveness in Patients Undergoing Laparoscopic Surgery
Surgical patients, especially those with insufficient blood volume and hypotension, often need fluid therapy. However, there is still a lack of simple and reliable indicators for judging transfusion responsiveness in some types…
- Trial name
- NCT04030221
- Testing
- fluid infusion
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Liver Transplantation
Validity of Mini Fluid Challenge Post Liver Transplantation
our study aim to assess the validity of using mini fluid challenge to assess the volaemic status of patients after liver transplantation
- Trial name
- NCT03396159
- Testing
- mini fluid challenge
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kasr El Aini Hospital
Hypovolemia, Fluid Overload
Prediction of the Effect of Fluid Administration Using Arterial Pressure and Ventilator Data During Abdominal Surgery
It is well known, that patients with circulatory impairment sometimes, but not always, benefit from intravenous fluids. Predicting if a fluid administration will improve circulation is therefore of substantial clinical interest.
- Trial name
- NCT04298931
- Testing
- Series of ventilator settings
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- University of Aarhus
Septic Shock, Hypovolemia
Assessment of Fluid Responsiveness in Septic Shock Patients, Can End-tidal co2 Measurement Help?
Fluid therapy is important in patients with sepsis and septic shock. There are many invasive and non-invasive methods to assess fluid responsiveness in patients.
- Conditions
- Septic Shock, Hypovolemia, Sepsis
- Trial name
- NCT05557461
- Testing
- End-tifdal co2, systolic, diastolic blood pressure, ppv values and vci distensibility
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bozyaka Training and Research Hospital
Septic Shock
Carotid Doppler and EEOT for Fluid Responsiveness Prediction
Fluid responsiveness prediction prior to fluid challenge administration is a topic of interest, which has been extensively investigated, but remains challenging.
- Trial name
- NCT04470856
- Testing
- End-expiratory occlusion test (EEOT)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Pediatric ALL, Fluid Overload
The Ratio of Femoral Vein Diameter to Femoral Artery Diameter to Predict Fluid Responsiveness in Children
The hypothesis of the study will be that the ratio of femoral vein diameter to femoral artery diameter will have correlation with fluid status in pediatrics.
- Trial name
- NCT05992246
- Testing
- Ratio of Femoral Vein Diameter to Femoral Artery Diameter
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Tanta University
Shock
Distensibility Index of Inferior Vena Cava in Assessing Fluid Responsiveness: The Impact of Spontaneous Respiratory Effort
This study explored how inspiratory effort affects the accuracy of the distensibility index of inferior vena cava (dIVC) in assessing fluid responsiveness (FR).This prospective observational study was conducted in an intensive…
- Trial name
- NCT07644494
- Testing
- explored how inspiratory effort affects the accuracy of the distensibility index of inferior vena cava in assessing fluid responsiveness
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Jingyuan,Xu
Hypotension
Use of Ultrasonography to Determine Fluid-responsiveness for Shock in a Population of Intensive Care Unit Patients
The objective of our study is to determine the correlation of transthoracic ultrasonographic indices of fluid responsiveness to changes in direct measures of cardiac output and to compare them to other established predictors of…
- Trial name
- NCT01680770
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- University of Chicago
Septic Shock, Fluid Reponsiveness
This Study Compares Two Noninvasive Dynamic Tools: Lung Ultrasound and Transthoracic Echocardiography Using LVOT VTI. It Aims to Measure the Sensitivity and Specificity of LUS in Guiding Fluid Resuscitation and Early Detection of Fluid Responsiveness and to Prevent Volume Overload
Reliability of the LVOT-VTI versus lung ultrasonography for early detection of fluid intolerance during fluid resuscitation of septic patients.
- Trial name
- lvotvti (NCT07797751)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hypovolemia, Hypervolemia
Perioperative Fluid Therapy Optimization in Spinal Surgery
The decision to give fluids perioperatively could be based on methods used to identify preload responsiveness, either invasive or noninvasive estimates of stroke volume variation during mechanical ventilation.
- Trial name
- NCT03644654
- Testing
- Standard care group, Noninvasive monitoring group
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Hradec Kralove