Clinical trials: Fluid Responsiveness
Hemodynamic Instability
Accuracy of the Pleth Variability Index to Predict Fluid Responsiveness in Liver Transplantation
The aim of this study is to compare the accuracy of PVI (pleth variability index)
- Trial name
- NCT01792011
- Testing
- PVI-guided fluid management
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Inonu University
Hemodynamic Instability
Pulse Pressure Variation Helps to Predict Fluid Responsiveness in Patients Ventilated With Low Tidal Volumes
Objective: To determine the value of pulse pressure variation (ΔRESPPP) to predict fluid responsiveness in patients ventilated with low tidal volumes (VT), and to investigate whether a lower ΔRESPPP cut-off point should be used…
- Trial name
- NCT01569308
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Cardiovascular System
Respiratory Variability in Aortic Blood Velocity Measured by Suprasternal View as an Indicator of Fluid Responsiveness
Respiratory changes in aortic blood velocity have been described as an indicator of fluid responsiveness when measured in the left ventricular outflow tract by trans esophageal echography.
- Trial name
- SUPRA-PAM (NCT02791984)
- Testing
- Fluid challenge with 250 ml of Ringer Lactate
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Hospices Civils de Lyon
Hypovolemic
Corrected Flow Time in the Carotid Artery as a Predictor of Fluid Responsiveness in Mechanically Ventilated Patients With Low Tidal Volume in the Intensive Care Unit
The purpose of this study is to evaluate predictability of carotid corrected flow time for fluid responsiveness in mechanically ventilated patients with low tidal volume in the intensive care unit.
- Trial name
- NCT04139031
- Testing
- Ultrasonographic measurement of corrected flow time in carotid artery
- Where
- South Korea
- Volunteers
- 37 people
- Sponsor
- Yonsei University
Circulatory Failure
the Impact of Manual or Mechanical Ways to Perform PLR on the Accuracy of Evaluation of Fluid Responsiveness
Our goal was to study the impact of different ways to perform passive leg raising (PLR) on the accuracy of evaluation of fluid responsiveness.
- Trial name
- PLR (NCT06285331)
- Testing
- Automatic Bed, Manual
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Southeast University, China
Circulatory Failure, Critical Illness
Role of End-Tidal CO2 During Passive Leg Raising to Predict Fluid Responsiveness in ICU
This prospective observational study evaluates whether monitoring changes in exhaled carbon dioxide (End-Tidal CO2 or EtCO2) during a "Passive Leg Raising" (PLR) test can reliably predict fluid responsiveness in critically ill…
- Conditions
- Circulatory Failure, Critical Illness, Hypovolemia
- Trial name
- NCT07304648
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Izmir Katip Celebi University
Lung Cancer, Lung Diseases
Positive End-expiratory Pressure (PEEP) in Predicting Fluid Responsiveness in Patients Undergoing One-lung Ventilation
The present study is to evaluate the effect of positive end-expiratory pressure (PEEP) in predicting fluid responsiveness in patients undergoing one-lung ventilation.
- Trial name
- NCT03794414
- Testing
- PEEP challenge
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Surgery, Anesthesia
Validation of RPVi as a Parameter to Predict Fluid Responsiveness
This is a prospective, nonrandomized, sequential data collection study to evaluate the ability of RPVi to predict fluid responsiveness in comparison with other dynamic parameters including stroke volume variation (SVV) and/or…
- Trial name
- NCT03706430
- Testing
- Pulse CO-Oximeter sensor
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Masimo Corporation
Cardiac Surgical Procedures, Thoracic Surgical Procedures
Pulse Pressure Variation Measured During Valsalva Maneuver to Predict Fluid Responsiveness Under Open-chest Condition
Pulse pressure variation (PPV) is a well-known dynamic preload indicator to predict fluid responsiveness. However, its usefulness in open-chest conditions has been equivocal.
- Conditions
- Cardiac Surgical Procedures, Thoracic Surgical Procedures, Sternotomy
- Trial name
- NCT02457572
- Testing
- Valsalva maneuver, Fluid loading
- Where
- South Korea
- Volunteers
- 55 people
- Sponsor
- Samsung Medical Center
Hemodynamics
Prediction of Volume Responsiveness in Presence of Left Ventricular Diastolic Dysfunction
The ability of the global end-diastolic volume index (GEDVI), stroke volume variation (SVV) and pulse pressure variation (PPV) for prediction of fluid responsiveness in presence of left ventricular diastolic dysfunction is still…
- Trial name
- NCT02441621
- Testing
- passive leg raising, premedication, intubation and mechanical ventilation
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Hospital Schleswig-Holstein
Sepsis, Circulatory Failure
Respiratory Variations For Predicting Fluid Responsiveness 2
Objectives: To investigate whether respiratory variations of inferior vena cava diameters (cIVC) predict fluid responsiveness in spontaneously breathing patients with septic acute circulatory failure and irregular heartbeats.
- Conditions
- Sepsis, Circulatory Failure, Respiratory Physiological Phenomena
- Trial name
- ReVaPreF2 (NCT03066375)
- Testing
- Echocardiography-Doppler
- Where
- France
- Volunteers
- 55 people
- Sponsor
- University Hospital, Lille
General Anesthesia
The Utility of Pulse Pressure Variation to Predict the Fluid Responsiveness During Pneumoperitoneum and Reverse-Trendelenburg Position
The purpose of this study is to investigate the validity of pulse pressure variation to predict fluid responsiveness in patients undergoing robotic or laparoscopic gastrectomy.
- Trial name
- NCT02771067
- Testing
- Fluid infusion
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Cardiac Surgery
Internal Jugular Vein Distensibility to Predict Fluid Responsiveness in Patients After Cardiac Surgery
The purpose of the study was to verify the efficacy of using internal jugular vein (IJV) size and distensibility as an index of fluid responsiveness in mechanically ventilated patients after cardiac surgery.
- Trial name
- NCT02852889
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Zhongshan Hospital
Shock, Circulatory Failure
Echocardiographic Prediction of Fluid Responsiveness After a Mini-fluid Challenge in Non-ventilated Patients With Shock
The main objective of this study is to show that the variation of the subaortic velocity time integral after a mini test by filling 100 cc of normal saline over 1 minute (ΔITV100) is predictive of response to filling (defined as…
- Trial name
- IVT NonVent (NCT01590511)
- Where
- France
- Volunteers
- 71 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
To Assess the Ability of PI to Detect Preload Responsiveness
Changes in Pulse-Oximetry Perfusion Index Induced by Tidal Volume Challenge Versus Fluid Volume Challenge to Detect Preload Responsiveness in Mechanically Ventilated Patients With Low Tidal Volume
The primary goal of this study was to assess the ability of PI changes induced by a Vt challenge or fluid challenge test to detect preload responsiveness in critically ill adult patients on mechanical ventilation with low-tidal…
- Trial name
- NCT06673862
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Benha University
End Tidal Carbon Dioxide, Cardiometry
Correlation Between Changes in End-Tidal Carbon Dioxide and Stroke Volume Variation Detected by Electrical Cardiometry as A Predictor of Fluid Volume Responsiveness in Hemodynamically Unstable Patients in the Intensive Care
This study will be conducted to assess the role of end-tidal carbon dioxide (PETCO2) monitoring to predict the fluid volume responsiveness in correlation with stroke volume variation detected by electrical cardiometry in patients…
- Conditions
- End Tidal Carbon Dioxide, Cardiometry, Fluid Responsiveness, Shock
- Trial name
- NCT03932617
- Testing
- end tidal carbon dioxide by capnography
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Sepsis, Fluid Overload
Comparison of Non-Invasive Methods of Assessing Fluid Responsiveness in ED and ICU Patients
Accurate assessment of fluid responsiveness (FRes) is central to guiding fluid management in septic and critically ill patients.
- Conditions
- Sepsis, Fluid Overload, Hypovolemia
- Trial name
- FRESEDICU (NCT02679625)
- Testing
- Ultrasound and NICOM
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Olive View-UCLA Education & Research Institute
Coronary Artery Bypass Graft
FLuid Responsiveness Prediction Using EXtra Systoles
In this study, the investigators propose to investigate a novel technique for fluid responsiveness prediction. It is based on the occurrence of an extra systole, which induces a preload variation: Extra systoles are comprised by…
- Trial name
- NCT03002129
- Testing
- fluid challenge
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- University Medical Center Groningen
Cardiac Surgical Procedures, Hemodynamics
Structured Hemodynamic Assessment to Guide Care After Cardiac Surgery
This multicenter pilot randomized controlled trial will evaluate whether providing treating physicians with a structured hemodynamic assessment influences care after cardiac surgery.
- Conditions
- Cardiac Surgical Procedures, Hemodynamics, Fluid Therapy, Acute Kidney Injury
- Trial name
- UTF-in-CVICU (NCT07792707)
- Testing
- Expert Report of a Structured Hemodynamic Assessment, Standard Care (in control arm)
- Where
- 2 sites in Canada
- Volunteers
- 75 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Monitoring During Anesthesia
Internal Jugular Vein Distensibility in Assessment of Fluid Responsiveness in Donors of Living Donor Liver Transplantation
Egypt has a very high prevalence of HCV and a high morbidity and mortality from chronic liver disease, cirrhosis, and hepatocellular carcinoma. Approximately 20% of Egyptian blood donors are anti-HCV positive.
- Trial name
- NCT03391037
- Testing
- Internal Jugular Vein Distensibility
- Volunteers
- 40 people
- Sponsor
- Ain Shams University