Clinical trials: Fluid Restriction
Fluid Overload
Intradıalytıc Weıght Control In Hemodıalysıs Patıents
The aim of this observational study is to determine the effect of a dialysis gown designed according to the empowerment model on changes in weight control behaviors among gown group patients during the intradialytic period.
- Trial name
- DialysisSuit (NCT07030361)
- Testing
- suit group, training group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Balikesir University
Acute Heart Failure (AHF)
Restrictive Versus Liberal Fluid Intake in Acute Decompensated Heart Failure
The aim of this clinical trial is to learn whether a thirst-driven, liberal fluid-intake strategy is comparable to a fluid-restriction strategy in patients hospitalized for acute decompensated heart failure (ADHF).
- Trial name
- RELIEF-AHF (NCT07400991)
- Testing
- Fluid restriction strategy, Thirst-driven, liberal fluid intake
- Where
- Denmark
- Volunteers
- 420 people
- Sponsor
- Gødstrup Hospital
Pancreaticoduodenectomy
The Use of a Restrictive Fluid Regimen With Hypertonic Saline for Patients Undergoing Pancreaticoduodenectomy
The Whipple operation is a complex surgical procedure involving the removal of the head of the pancreas, bile duct, and a portion of the intestine (duodenum) that is performed for patients who have cancer or some other condition…
- Trial name
- NCT01428050
- Testing
- 3% NaCl Solution, Lactated Ringers Solution
- Where
- United States
- Volunteers
- 264 people
- Sponsor
- Thomas Jefferson University
Colorectal Surgery, Postoperative Complications
Restricted Fluid Therapy in Colorectal Surgery
This is a protocol for a trial carried out from 1999 to 2002. At that time, surgical patients received a large volume of intravenous saline during operations on the colon or the rectum, often so much fluid that their bodyweight…
- Trial name
- NCT03537989
- Testing
- Saline
- Volunteers
- 172 people
- Sponsor
- Holbaek Sygehus
Surgery, Perioperative Care
Restricted Intravenous Fluid Regime Effects on Immunological Indicators of Elderly Patients Operated for Abdominal Cancer
The purpose of this study is to find out whether perioperative fluid restriction influence on postoperative immunological function. And discuss the probable mechanism that fluid restriction regime effect on clinical data.
- Conditions
- Surgery, Perioperative Care, Immunization, Abdominal Neoplasms
- Trial name
- NCT01399814
- Testing
- perioperative fluid management, perioperative fluid treatment
- Volunteers
- 179 people
- Sponsor
- Nanjing PLA General Hospital
Dehydration, Menstruation
Hydration & Female Life Stages
Female life stages including premenopausal, perimenopausal, postmenopausal, are characterized by changing concentrations and patterns of hormones.
- Conditions
- Dehydration, Menstruation, Pre-menopause, Peri-menopausal Women
- Trial name
- NCT07653620
- Testing
- electrolyte beverage
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Sepsis
A Randomized Controlled Trial of a Conservative Fluid Balance Strategy for Patients With Sepsis and Cardiopulmonary Dysfunction (BALANCE Study)
Sepsis is a common inflammatory response to infection characterized by hypovolemia and vasodilation for which early administration of intravenous fluids has been suggested to improve outcomes.
- Trial name
- BALANCE (NCT02159079)
- Testing
- Conservative Fluid Management Strategy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University
Fluid Overload
Restrictive or Doppler-guided Fluid Treatment in Colorectal Surgery
This is a clinical randomised double blinded multicentre trial of two different fluid treatments during colorectal surgery in an enhanced recovery programme A restricted fluid regimen aiming at zero fluid balance and less than…
- Trial name
- NCT03677622
- Testing
- Voluven to near maximal stroke volume of the heart
- Volunteers
- 150 people
- Sponsor
- Holbaek Sygehus
Acute Kidney Injury, Critical Illness
REVERSE-AKI Randomized Controlled Pilot Trial
Observational studies among patients with acute kidney injury (AKI) have shown an association with fluid accumulation and increased mortality.
- Trial name
- REVERSE-AKI (NCT03251131)
- Testing
- Restrictive fluid management
- Where
- 7 sites in Australia, Belgium and 3 more
- Volunteers
- 100 people
- Sponsor
- Helsinki University Central Hospital
Hydrops Fetalis, Fetal Growth Retardation
Amniotic Fluid Tandem Mass Spectrometry for Pregnancies Complicated by NIH and Severe Symmetrical IUGR
The objective of this pilot study is to prospectively evaluate amniotic fluid of pregnancies complicated by non-immune hydrops and severe symmetrical intrauterine growth restriction by tandem mass spectrometry for inborn errors…
- Trial name
- TandemMS (NCT00143039)
- Testing
- Tandem MS test for inborn errors of metabolism
- Where
- 11 sites in United States
- Volunteers
- 48 people
- Sponsor
- Obstetrix Medical Group
Bronchopulmonary Dysplasia
Restricted Versus Liberal Fluid Intake for Prevention of Bronchopulmonary Dysplasia
The aim of this study is to determine whether restricted fluid intake (135 ±5 mL/kg/day) compared to liberal fluid intake (165 ±5 mL/kg/day) from day 8 of life reduces the incidence of bronchopulmonary dysplasia (BPD) at 36 weeks…
- Trial name
- RELIEF (NCT06954142)
- Testing
- Fluid restriction, Liberal fluid intake
- Where
- 9 sites in Switzerland
- Volunteers
- 750 people
- Sponsor
- University Children's Hospital Basel
Prostate Cancer, Surgery
Electric Cardiometry-Guided Standard Versus Restricted Fluid Therapy In Robotic Prostaectomy
Fluid therapy during surgery is an important factor that is related to long term mortality and morbidity and it's directly related to tissue perfusion as well.
- Conditions
- Prostate Cancer, Surgery, Fluid Overload, Lactate Blood Increase
- Trial name
- NCT07626151
- Testing
- Liberal Fluid Therapy, Restricted Fluid Therapy
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Nazmy Edward Seif
ENT Surgery
Pneumatic Compression of the Legs to Reduce Fluid Demand in Minor Surgery
Fluid restriction has become of great interest in perioperative care. There is, however, a conflict of interest between fluid restriction and hemodynamic stability.
- Trial name
- NCT01072305
- Testing
- Intermittent pneumatic compression (IPC)
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- University Hospital, Bonn
Critical Illness, Pediatrics
Effect of Giving Reduced Fluid in Children After Trauma
This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid…
- Conditions
- Critical Illness, Pediatrics, General Surgery, Fluid Therapy
- Trial name
- NCT04201704
- Testing
- Balanced crystalloid solution volume administration, Packed Erythrocytes Units, Blood Product Unit volume, Plasma volume
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- Columbia University
Chorioamnionitis, Chorioamnionitis Affecting Fetus or Newborn
Amniotic Fluid & the Preterm Gut
Background: Necrotizing enterocolitis (NEC) and sepsis in preterm infants have been linked to intestinal immaturity and preclinical gut microbiota alterations.
- Conditions
- Chorioamnionitis, Chorioamnionitis Affecting Fetus or Newborn, Necrotizing Enterocolitis of Newborn, Neonatal Sepsis, Early-Onset
- Trial name
- AMFIBIE (NCT07152106)
- Where
- 2 sites in Netherlands
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
Heart Failure, Systolic, Heart Failure; With Decompensation
Fluid Restriction in Patients With Heart Failure
There is a concept increasingly consolidated by clinical evidence that at each hospitalization due to HF decompensation there is a substantial loss of quality of life, which is associated with an initial period of great clinical…
- Conditions
- Heart Failure, Systolic, Heart Failure; With Decompensation, Pulmonary Congestion
- Trial name
- NCT04611594
- Testing
- Fluid restriction
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Hyponatremia, Dilutional Hyponatremia
Effects of Tolvaptan vs Fluid Restriction in Hospitalized Subjects With Dilutional Hyponatremia
The purpose of this study is to determine if hospitalized patients with symptomatic hyponatremia treated with tolvaptan are in the hospital for less time than patients treated with fluid restriction.
- Conditions
- Hyponatremia, Dilutional Hyponatremia, Inappropriate ADH Syndrome
- Trial name
- SALACIA (NCT01227512)
- Testing
- tolvaptan, Fluid Restriction
- Where
- 56 sites in United States
- Volunteers
- 124 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Abdominal Aortic Aneurysm > 5.5 cm Effect of a Restricted Intravenous Fluid Regime on Complications and Hospital Stay After the Minilaparotomy AAA Repair.
Restrictive Versus Standard Fluid Regime in Elective Minilaparotomy Abdominal Aortic Aneurysm Repair
Elective minilaparatomy abdominal aortic aneurysm (AAA) repair is associated with a significant number of complications involving respiratory, cardiovascular, gastrointestinal and central nervous system, and mortality ranging up…
- Trial name
- NCT01939652
- Testing
- Restrictive VS Standard Fluid Regime, Drag: Crystalloids and Colloids
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Clinical Center Tuzla
Surgery
Fluid Administration Limited by Lung Ultrasonography in the Operating Room: Correlation to Stroke Volume Variation.
The possibility of exploring the lungs by lung ultrasound, a non-invasive tool, is becoming increasingly popular for anesthesiologists.
- Trial name
- ORFALU (NCT03502460)
- Testing
- Operating Room Fluid Administration Lung Ultrasound
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Bowel Surgery
Restricted Fluid Regimen in Open Abdominal Bowel Surgery
Liberal intravenous fluid resuscitation during open abdominal surgery may predispose the patients to multiorgan dysfunction, prolong hospital stay and increase postoperative morbidity.
- Trial name
- NCT00456703
- Testing
- intraoperative fluid management, fluid restriction
- Where
- United States
- Sponsor
- Beth Israel Deaconess Medical Center