Clinical trials: Fluid Retention
Hydration, Fluid Retention
Hydration Dynamics and Influence of Beverage Composition
The study examines interactions between fluid availability in the gut and fluid retention in the body. The relative rate of fluid uptake, the expansion of the plasma volume, and percent of fluid retained by the body will be…
- Conditions
- Hydration, Fluid Retention, Dehydration
- Trial name
- NCT05111392
- Testing
- Oral Rehydration Solution 1, Oral Rehydration Solution 2
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Dental Caries
Evaluation of Plaque Fluid Fluoride Retention From Fluoride Toothpastes
The purpose of this study is to investigate the efficacy of different sodium fluoride (NaF) containing toothpastes in prevention of dental caries.
- Trial name
- NCT00708305
- Testing
- Sodium Fluoride (NaF)
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Fluid Retention, Sodium Retention
The Effect of AMP Human Sodium Bicarbonate Lotion on Dehydrated Heat Stress
The primary purpose of the proposed study is to evaluate the effects of a topical sodium bicarbonate lotion (PR Lotion, AMP Human, Park City, UT) on measures of hydration status and fluid balance in humans when exposed to the…
- Conditions
- Fluid Retention, Sodium Retention, Heat Stress, Dehydration (Physiology)
- Trial name
- AMP2 (NCT05092854)
- Testing
- PR Lotion - AMP Human Performance, AminoVital - Rapid Recovery
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Fluid Retention Due to Heart Failure
A Mass Balance Study of [14C]HRS-9057 for Injection in Healthy Participants
This study is a single-center, open-label, single-dose phase I clinical trial. The trial is divided into four periods: screening, baseline, treatment, and follow-up
- Trial name
- NCT07681479
- Testing
- [14C]HRS-9057
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
Other Acute Illnesses Presenting to the Hospital, Heart Failure
Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program
This VA QUERI Partnered Evaluation Initiative will evaluate the impact of an immersive Point-of-care Ultrasound (POCUS) Training Course on provider skill acquisition and retention; the frequency of POCUS use by trained providers…
- Conditions
- Other Acute Illnesses Presenting to the Hospital, Heart Failure, Pneumonia, Deep Venous Thrombosis
- Trial name
- NCT03296280
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Urinary Retention
Post Hysterectomy Benefits of Retained Cystoscopy Fluid
The purpose of this research study is to compare outcomes for women in two study arms that include retaining the cystoscopy distending fluid after minimally invasive hysterectomy verses completely emptying the cystoscopy…
- Trial name
- NCT03646136
- Testing
- Retained fluid, Emptied fluid
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Fluid Retention, Fluid Loss
The Effect of AMP Human Sodium Bicarbonate Lotion on Hydration
The purpose of this research study is to evaluate the effects of a topical sodium bicarbonate lotion on physiological and psychological responses associated with hydration status and fluid balance in humans during passive heat…
- Conditions
- Fluid Retention, Fluid Loss, Sodium Retention, Cognitive Change
- Trial name
- AMPlify (NCT04598386)
- Testing
- PR Lotion - AMP Human Performance
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Fluid Retention, Beverage Hydration Index
Efficacy of Different Oral Rehydration Solutions on the Hydration Status of Healthy Males
Dehydration lowers both physical and mental performance if it is severe enough. Performance declines are more pronounced in hot conditions or after prolonged strenuous activity such as exercise.
- Conditions
- Fluid Retention, Beverage Hydration Index, Hydration Status
- Trial name
- NCT05428774
- Testing
- Test product 1, Test product 2
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Liquid I.V.
Fluid Restriction
Fluid Restriction After Stapled Hemorrhoidopexy
BACKGROUND: Conventional hemorrhoidectomy leads to a high urinary retention rate and fluid restriction is commonly recommended to minimize complications.
- Trial name
- NCT04459039
- Testing
- 1000 mL 0.9% sterile saline, 250 mL 0.9% sterile saline
- Where
- Taiwan
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Dental Caries
Long-term Release of Fluoride Formed on Enamel by Fluoride Gel or Varnish to Biofilm Fluid
The anticaries effect of professional fluoride application has been associated with the formation of calcium fluoride-like products ("CaF2") on dental surface, which may function as a slow release fluoride reservoir.
- Trial name
- NCT02486458
- Testing
- 5% sodium fluoride varnish, 1.23% sodium fluoride acidic gel
- Where
- Brazil
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Healthy Adult Volunteers
Metabolism of Isotonic Versus Hypotonic Maintenance Solutions in Fasting Healthy Adults
The prescription of intravenous maintenance solutions - although widespread - lacks important data on the optimal sodium and potassium content, which has given rise to an important debate in the scientific literature.
- Trial name
- MIHMoSA (NCT02822898)
- Testing
- NaCl 0.9% in Glucose 5% with 40mEq Potassium, Glucion 5%
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Acromegaly
Cardiac (CMRI) Assessment of Acromegaly
In this study, the investigators will evaluate the cardiac structure and function, focusing on the myocardial water content and interstitial fibrosis, in patients with active acromegaly in comparison with 1) healthy volunteers…
- Trial name
- ACROCOEUR (NCT02948322)
- Testing
- CMRI, Gadolinium, OGTT
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hydration Status, Substrate Metabolism During Exercise
The Effect of Hydration Status on Substrate Oxidation at Rest and During Light and Moderate Exercise
Metabolic flexibility is the ability to properly switch between fat and carbohydrate stores to use for energy under different conditions (rest, feeding, exercise).
- Trial name
- NCT07298863
- Testing
- Part 1 - Exercise Trial, Part 1 - Experimental Trial, Part 2 - Oral Glucose Tolerance Test
- Where
- 2 sites in United States, Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Hydration
Effect of Glycerol-Electrolyte Beverages on Fluid Balance in Healthy Euhydrated Men and Women at Rest
The objective of this study is to determine the effect of consumption of drinks with varying amounts of glycerol and electrolytes on fluid balance at rest.
- Trial name
- NCT06185595
- Testing
- Beverage. Incomplete block where each participant will complete 3 of the 6 possible glycerol-sodium blends in random order.
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Fluid Retention Tissue, Perfusion; Complications
Weightlessness Associated Cephalad Fluid Shifts; The Potential to Evaluate Venous and Lymphatic Dysfunction
In the weightlessness of space and significant alterations of terrestrial 1 g (1 gravity equivalent) head-to-foot hydrostatic pressure gradients, astronauts experience a dramatic fluid redistribution of ~ 2 liters from the legs…
- Trial name
- NIID (NCT06405282)
- Testing
- Manual Lymphatic Drainage, Near infrared spectroscopy, Temperature
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Dehydration
Effects of Amino Acid/Electrolyte-based Beverages on Hydration Status
Older adults typically do not drink later in the day to avoid the necessity of interrupting sleep to urinate. Sometimes they also limit ingestion of fluids to avoid the need to urinate when engaged in certain activities such as…
- Trial name
- NCT03559101
- Testing
- Distilled water, Medical Food 1, Medical Food 2
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- W. Larry Kenney
Body Fluid Retention, Impedance
Effect of Passive Leg Raising for Fluid Responsiveness
Changes in volumetric hemodynamic parameters and fluid overload (Cardiac Index,Stroke Volume, Thoracic Fluid Content, Systemic Vascular Resistance) were measured using a impedance cardiography (ICG) (CardioScreen 1000 …
- Conditions
- Body Fluid Retention, Impedance, Cardiac Output, Low
- Trial name
- NCT02702544
- Testing
- CardioScreen 1000 - Haemodynamic Measurement System, Medis, SCHILLER, BR-102 plus - Ambulatory Blood Pressure Monitoring System
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Dehydration (Physiology)
Rehydration With a Trace Mineral Supplement
It is well established that post-exercise rehydration with electrolyte solutions is more effective than plain water. However, most commercially available drinks are high in electrolytes but lack some essential trace minerals.
- Trial name
- TRACE (NCT06858904)
- Testing
- ConcenTrace, ZeroLyte
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Side Effects of Creatine Monohydrate Dosing
Gastrointestinal and Fluid Retention Symptoms Associated With Creatine Monohydrate With and Without Loading Dose Over 28 Days of Supplementation
This study aimed to investigate the incidence and severity of GI symptoms associated with daily CM supplementation, with and without a loading phase, in healthy male and female adults.
- Trial name
- NCT07176325
- Testing
- Creatine Monohydrate
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vireo Systems, Inc.
Beverage Hydration Index
Manipulation of Whey Permeate Formulation for Better Fluid Retention.
The main aim of this clinical trial is to compare the beverage hydration index of three different beverages in primary school-aged children.The Beverage Hydration Index (BHI), compares the hydration value of beverages against…
- Trial name
- NCT06967454
- Testing
- Water, Semi-skimmed milk, Whey permeate
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Northumbria University