Clinical trials: Fluoride Poisoning
Dental Fluorosis
Presence of Enamel Fluorosis in Libyan Children
Fluorosis is caused by hypomineralization in the enamel due to increased fluoride ingestion during early childhood (Cawson.1, Wong et al. 2, and Sudhir 3).
- Trial name
- NCT03746990
- Volunteers
- 1,935 people, healthy volunteers welcome
- Sponsor
- Ajman University
Dental Fluorosis
Clinical Evaluation of Dental Fluororsis Treatment Modalities
Background: Various treatment modalities are available to improve esthetics of fluorosed teeth based on its severity. Aim: evaluate the clinical performance of different minimal invasive treatment protocols on mild to moderate…
- Trial name
- NCT05204277
- Testing
- Opalescence™ boost™ PF 40%, Opalustre™, MI-Paste Plus®
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Fluorosis, Dental, Non-Fluoride Enamel Opacities
Treatment of Hypersensitivity Using Diode Laser and Desensitising Agent on Fluorosed and Non-fluorosed Teeth
The present study was designed as a randomised controlled clinical trial which was unicenter, double-blinded, parallel designed study, according to the Consolidated Standards of Reporting Trials (CONSORT) criteria, 2010.
- Conditions
- Fluorosis, Dental, Non-Fluoride Enamel Opacities, Dentin Sensitivity
- Trial name
- NCT03237793
- Testing
- Fluorosed Group, Non Flourosed Group
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Dental Caries, Dental Fluorosis
Anticaries Potential and Fluorosis Risk From Different Fluoride Toothpastes
Fluoride toothpaste has been associated not only with declining dental caries prevalence but also with an increase in dental fluorosis.
- Trial name
- NCT01589991
- Testing
- Toothpaste
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Dental Fluorosis
Clinical Severity of Dental Fluorosis and Associated Risk Factors Among a Group of Children in Rural Region, Dendera Center in Egypt
The goal of our observational study is evaluation of the clinical severity of dental fluorosis and associated risk factors among a group of children (8-12 years old) in a rural region, Dendera center, Egypt.
- Trial name
- NCT07138456
- Where
- Egypt
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Dental Fluoroses
Iowa Fluoride Study/Iowa Bone Development Study
A cohort of newborns was recruited for the Iowa Fluoride Study from 1992-95 to assess the complex relationships among fluoride intakes, fluoride exposures, dental fluorosis, and dental caries.
- Conditions
- Dental Caries, Dental Fluoroses, Bone Density
- Trial name
- (IFS/IBDS) (NCT03547128)
- Volunteers
- 1,882 people, healthy volunteers welcome
- Sponsor
- Steven M Levy
Dental Caries in Children, Tooth Erosion
3D Scanning as an Advanced Tool for Identifying Tooth Lesions in Children
This study focuses on assessing dental caries, erosive tooth wear, and fluorosis in primary teeth using a 3D intraoral digital scanner.
- Conditions
- Dental Caries in Children, Tooth Erosion, Fluorosis, Dental, Dental Caries
- Trial name
- NCT06829550
- Testing
- indirect- 3D digital scanning
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Indiana University
Dental Caries, Dental Fluorosis
Fluoride Bioavailability After Ingestion of Water or Foods Prepared With Fluoridated Water
The importance of fluoridated water to control caries is well recognized. Although the mode of action of fluoridated water is known (related to a slight increase in fluoride concentration in saliva/dental biofilm in individuals…
- Trial name
- NCT01978041
- Testing
- Meal prepared with non fluoridated water, Meal prepared with fluoridated water, Non fluoridated water
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Dental Fluoroses
This is the Comparison of Clinical Effectiveness of Hydrochloric Acid-pumice Compound and Sodium Hypochlorite-pumice Compound Used in Microabrasion Technique for the Treatment of Dental Fluorosis. Change in Tooth Shade Was Checked Before and After the Procedure.
To compare the clinical effectiveness of hydrochloric acid-pumice compound and sodium hypochlorite-pumice compound in treating dental fluorosis using microabrasion technique.
- Trial name
- NCT05339503
- Testing
- enamel microabrasion
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fatima Jinnah Dental College
Fluorosis, Dental, Fluorosis
Design of a Multicomponent Intervention to Reduce the Risk of Exposure Fluorine
Introduction Systemic exposure to fluoride is a significant challenge for global public health; this is because although fluoride prevents dental caries, prolonged exposure to high concentrations can cause adverse effects on…
- Trial name
- NCT07232888
- Testing
- multicomponent intervention, Conventional intervention
- Where
- Colombia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad Antonio Nariño
Dental Fluorosis, Dental Caries
Effect of pH and Fluoride Concentration of Dentifrices on Caries Control
This study aims to assess the overall effect of pH and fluoride concentration of liquid dentifrices in the control of children dental caries of a fluoridated area, through visual inspection and the quantitative light-induced…
- Trial name
- EPHFCDCC (NCT01049503)
- Testing
- Low fluoride and conventional dentifrices with different pH
- Where
- Brazil
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Fluorosis
Clinical Evaluation of Different Minimal Invasive Treatment Modalities of Mild to Moderate Dental Fluorosis Using A Visual Analog Scale
This study was conducted for clinical evaluation of the quality of different minimal-invasive treatment modalities and combination treatments in esthetics improvement of mild to moderate fluorosed teeth using two different…
- Trial name
- NCT05051748
- Testing
- Opalescence™ boost™ PF 40%, Opalustre™, MI-Paste Plus®
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Dental Fluorosis
Systemic Fluoride Bioavailability From Toothpastes Containing Calcium Carbonate or Silica as Abrasives
The risk of dental fluorosis development is related to the systemic exposure to fluoride during enamel formation. Currently, diet and fluoride toothpastes are the main sources of fluoride to children at the age-risk for fluorosis…
- Trial name
- NCT01571050
- Testing
- Purified water, Fresh MFP/CaCO3 toothpaste, Fresh NaF/SiO2 toothpaste
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Fluorosis, Dental, Fluorosis
Design of a Multicomponent Intervention to Reduce the Risk of Exposure Fluorine
Introduction Systemic exposure to fluoride is a significant challenge for global public health; this is because although fluoride prevents dental caries, prolonged exposure to high concentrations can cause adverse effects on…
- Trial name
- NCT07359937
- Testing
- multicomponent intervention, Conventional intervention
- Where
- Colombia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad Antonio Nariño
Healthy Individuals
Fluoride Intake From Toothbrushig With Children's or Regular Toothpastes
There are controversial data about fluoride intake by children when tooth brushing with children's or regular toothpastes. However, a study have showed that children were exposed to a dose of 0.051 mg F/Kg/day and 0.046 mg…
- Trial name
- F (NCT01568541)
- Testing
- Regular toothpastes, Children's toothpastes
- Where
- 3 sites in Brazil
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Caries, Dental, Gingivitis
Dental Health Epidemiology Among Israel Defense Forces (IDF) Recruits
An epidemiological survey for prevalence description of dental morbidity (caries, gingivitis, dental trauma and fluorosis) among Israel Defense Forces (IDF) general recruits.
- Conditions
- Caries, Dental, Gingivitis, Fluorosis, Dental Trauma
- Trial name
- NCT02958891
- Testing
- Data collection
- Where
- Israel
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Caries, Dental, Fluorosis, Dental
Dental Fluorosis Risk by the Use of Acidulated Fluoride Dentifrice
This research aimed to evaluate the risk of dental fluorosis by using an experimental fluoridated acidulated dentifrice compared to conventional dentifrices in two-to-four-year-old children residing in a non fluoridated area by…
- Trial name
- NCT03761485
- Testing
- Use of Dentifrice Fluoride
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba