Clinical trials: Flushing
Healthy Adult, Flushing
ALDH2 Genetic Testing in East Asian Community
The goal of this clinical trial is to learn whether education plus genetic testing for ALDH2*2 and ADH1B*2 is feasible and acceptable and whether it influences modifiable health behaviors in East Asian American adults who…
- Trial name
- NCT07392775
- Testing
- Genetic Test Results Return, Alcohol Flushing Education
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Postmenopausal Flushing, Postmenopausal Symptoms
Self-Management Box on Hot Flash in Postmenopausal Women
Aim of the study This study aims to evaluate the effect of a nurse-led menopause self-management box on hot flash frequency and menopause-specific quality of life among postmenopausal women.
- Trial name
- Self-Managemen (NCT07874893)
- Testing
- Components of Nurse-Led Menopause Self- Management Box
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Rosacea, Rosacea, Erythematotelangiectatic
Transcutaneous Auricular Vagus Nerve Stimulation Treatment for Rosacea
A single arm, pilot study among individuals with rosacea and at least moderate flushing or rednesss will be enrolled in a 4-week trial of taVNS.
- Conditions
- Rosacea, Rosacea, Erythematotelangiectatic, Flushing
- Trial name
- NCT07600424
- Testing
- Transaricular vagus nerve stimulation (taVNS)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Brigham and Women's Hospital
Type B Acute Aortic Syndrome, Thoracic and Thoracoabdominal Aneurysms With Crawford Extent I, II, III, or IV
A Standard Carbon Dioxide Flushing Protocol to Reduce Air Embolization During Thoracic Endovascular Aortic Repair
FlushTEVAR is a non-profit, interventional, randomized, controlled, single-blind, national multicenter study promoted by the University of Bologna and coordinated by the Vascular Surgery Unit of IRCCS Azienda…
- Trial name
- FlushTEVAR (NCT07734584)
- Testing
- Carbon dioxide pre-implant endograft flushing followed by saline flushing, Saline endograft flushing
- Where
- 4 sites in Italy
- Volunteers
- 90 people
- Sponsor
- University of Bologna
Facial Flushing
Treatment of Facial Flushing With Botulinum Toxin A Injections
The purpose of this study is to find out if botulinum toxin A (botox®) can be used to treat facial flushing. This study is a pilot study designed to determine feasibility of these procedures.
- Trial name
- NCT02216838
- Testing
- botulinum toxin A, Saline Control
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Haemodialysis Patients, Blockage of Tunnelled Central Venous Access Device
Pulsatile Flushing Technique in Reducing Blockage of T-CVAD for Haemodialysis Patients
This study investigates the effectiveness of pulsatile flushing techniques in reducing blockage in Tunnelled Central Venous Access Device (T-CVAD) among patients undergoing haemodialysis (HD) treatment at multiple renal centres…
- Conditions
- Haemodialysis Patients, Blockage of Tunnelled Central Venous Access Device, Pulsatile Flushing Technique
- Trial name
- Non-RCT HD (NCT07567456)
- Testing
- Pulsatile Flushing Technique (0.4s pause interval), Pulsatile Flushing Technique (1s pause interval), Bolus Flushing Technique
- Where
- Hong Kong
- Volunteers
- 591 people
- Sponsor
- Queen Elizabeth Hospital, Hong Kong
Rosacea, Redness
Evaluation of the Efficacy and Tolerance of Two Cosmetic Products in Subjects With Rosacea
Multicentric and double-blind randomised comparative clinical study in Argentina and Brazil. Under dermatological and ophthalmological control 4 visits: inclusion [Day(D)0], D28, D56, D84 Ethical committee required.
- Conditions
- Rosacea, Redness, Telangiectasia, Flushing
- Trial name
- NCT06582043
- Testing
- SCARCr tester 1
- Where
- 2 sites in Argentina, Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- NAOS Argentina S.A.
Postmenopausal, Postmenopausal Flushing
Influence of Iyengar Yoga on the Bio-functional Age of Postmenopausal Women
The purpose of this Study is to find out if Iyengar-Yoga has a rejuvenating effect on women after menopause. The biofunctional status of the study participants will be assessed before and after a 12-week yoga program.
- Trial name
- IIYBFAPW (NCT04705623)
- Testing
- Iyengar Yoga
- Where
- Switzerland
- Volunteers
- 72 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Postmenopausal Flushing, Hot Flashes
Reflexology Versus Acupressure on Sleep Disturbance and Hot Flashes
World health Organization (WHO) estimates that by 2030, 1.2 billion women will be over 50 years old. With a prevalence of 70%, a hot flash is the most distressing symptoms associated with menopause.
- Trial name
- NCT06499311
- Testing
- Foot Reflexology, Acupressure
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Cairo University
Erythema and Flushing Associated With Rosacea
Mirvaso® Gel and Dysport® for Erythema and Flushing of Rosacea
To evaluate the safety and efficacy of Mirvaso® Gel and Dysport® for erythema and flushing of Rosacea.
- Trial name
- NCT03508869
- Testing
- Mirvaso® (brimonidine) topical gel, 0.33%, Dysport®, Dysport® in conjunction with Mirvaso (brimonidine) topical gel, 0.33%
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Skin Laser & Surgery Specialists
Carcinoid Syndrome
An Efficacy and Safety Study of Somatuline Depot (Lanreotide) Injection to Treat Carcinoid Syndrome
The purpose of this study was to determine whether monthly deep subcutaneous (s.c.) injections of lanreotide Autogel (Somatuline Depot) were effective and safe in controlling diarrhoea and flushing by reducing the usage of s.c.
- Trial name
- ELECT (NCT00774930)
- Testing
- Lanreotide
- Where
- 54 sites in United States, Brazil and 9 more
- Volunteers
- 115 people
- Sponsor
- Ipsen
Menopausal Flushing
Neuropeptide Treatment for Hot Flushes During the Menopause
Placebo-controlled, double-blinded, cross-over clinical trial of a new investigational product
- Trial name
- NK3R (NCT02668185)
- Testing
- NK3R antagonist - AZD4901
- Where
- United Kingdom
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Peritoneal Carcinomatosis
Clinical Pharmacology of Platinum-based Hyperthermic Intraperitoneal Chemotherapy
Currently, there is a lack of knowledge on the effect of additional flushing after HIPEC on tumour platinum exposure, systemic platinum exposure and platinum concentration in drain exudate and thereby personal exposure.
- Trial name
- GUTOX (NCT03364907)
- Testing
- HIPEC with flushing afterwards, HIPEC without flushing afterwards
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Radboud University Medical Center
To Evaluate the Efficacy of Flushing the Uterine Cavity With Lidocaine Before Hysterosalpingo-Foam Sonography to Reduce Procedure-related Pain
Efficacy of Uterine Lidocaine Flushing in HyFoSy
To evaluate the efficacy of flushing the uterine cavity with lidocaine before Hysterosalpingo-Foam Sonography (HyFoSy) to reduce procedure-related pain.
- Trial name
- NCT04433611
- Testing
- 2% lidocaine, 0.9 % normal saline
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Assaf-Harofeh Medical Center
Flushing, Alcohol-Related Disorders
Treatment of Asian Flushing Syndrome With Topical Alpha Agonists
Asian Flushing Syndrome (AFS) is a genetic disease affecting approximately 70% of patients of East Asian descent characterized by severe flushing with minimal ethanol consumption.
- Conditions
- Flushing, Alcohol-Related Disorders, Aldehyde Dehydrogenase Deficiency
- Trial name
- NCT03497442
- Testing
- Brimonidine Tartrate
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Postmenopausal Flushing, Cardiovascular Risk Factor
Hot Flash as a Marker of Cardiovascular Risk in Recent Postmenopause: Effects of Non-hormonal Treatments
Hot flashes, vasomotor symptoms that affect many postmenopausal women, are associated with cardiovascular disease and endothelial dysfunction.
- Conditions
- Postmenopausal Flushing, Cardiovascular Risk Factor, Endothelial Dysfunction
- Trial name
- NCT03149419
- Testing
- Paroxetine
- Where
- Brazil
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Flushing, Hyperlipidemias
Effects of Psyllium on Niacin Tolerability
The purpose of this study is to determine whether psyllium is effective in reducing flushing due to niacin and also to measure the effect of niacin on cholesterol levels.
- Conditions
- Flushing, Hyperlipidemias, Dyslipidemias
- Trial name
- NCT03370848
- Testing
- Psyllium, Aspirin
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- VA Greater Los Angeles Healthcare System
Flushing
Effect of MK0524A on Flushing Caused by Niacin (0524A-056)
The primary objective of the study is to assess the effects of MK0524A in reducing flushing associated with niacin.
- Trial name
- NCT00533611
- Testing
- MK0524A, /Duration of Treatment : 4 Weeks, Comparator : niacin /Duration of Treatment : 1 Weeks
- Volunteers
- 330 people
- Sponsor
- Merck Sharp & Dohme LLC
Flushing
Endpoint Validation Study (0524A-015)
To determine the most effective daily dose of MK0524A when compared with placebo after the 8-week treatment period for Niacin Induce Flushing (NIF).
- Trial name
- NCT00533676
- Testing
- MK0524A, /Duration of Treatment : 8 Weeks
- Volunteers
- 165 people
- Sponsor
- Merck Sharp & Dohme LLC
Relapsing-Remitting Multiple Sclerosis
Phase 4 Study of Effect of Aspirin on Flushing in Dimethyl Fumarate-Treated Participants With Relapsing-Remitting Multiple Sclerosis
The primary objective of the study is to evaluate whether 150 mg enteric-coated aspirin (acetylsalicylic acid [ASA]) taken twice a day (BID) with dimethyl fumarate (DMF) administration or 75 mg enteric-coated ASA taken once daily…
- Trial name
- ASSURE (NCT02090413)
- Testing
- dimethyl fumarate, acetylsalicylic acid
- Where
- 21 sites in Ireland, United Kingdom
- Volunteers
- 241 people
- Sponsor
- Biogen