Clinical trials: Focal Liver Lesion
Contrast Media, Liver, Biopsy, Fusion
Added Value in Combined Use of Fusion Imaging and Contrast-enhanced Ultrasonography
So far, there have been studies showing that the CEUS-grafted technique has added value in biopsy and RFA, but no studies have compared the group using only fusion and the group using CEUS+fusion.
- Trial name
- NCT04487288
- Testing
- SONAZOID
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Hospital
Postoperative Bile Leak, Focal Liver Lesions
Prevention of Bile Leakage After Liver Resection in Children
Bile leakage is a clinically important complication after liver resection in children and may require prolonged drainage, additional radiological or endoscopic procedures, or repeat surgery.
- Trial name
- NCT07867522
- Testing
- prophylactic extrahepatic biliary drainage during liver resection
- Where
- Russia
- Volunteers
- 12 people
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Focal Liver Lesions
Phase 4 Paediatric Study to Evaluate Sonazoid Safety and Efficacy for Contrast-Enhanced Ultrasound Liver Imaging
Liver tumours, 40% of which are benign, account for 1% to 4% of all solid tumours in children. The benign tumours are mainly haemangiomas, liver hamartomas, and liver cell adenomas.
- Trial name
- NCT06639828
- Testing
- Contrast-Enhanced Ultrasound
- Where
- 6 sites in Germany, Italy and 1 more
- Volunteers
- 50 people
- Sponsor
- GE Healthcare
Liver Neoplasms
SonoVue®-Enhanced Ultrasound (US) Versus Unenhanced US for Focal Liver Lesion Characterization
The purpose of this study is to demonstrate the Sensitivity and Specificity of SonoVue®-enhanced ultrasound is superior to that of unenhanced ultrasound for the characterization of benign versus malignant FLLs using final…
- Trial name
- NCT00829413
- Testing
- SonoVue®
- Where
- United States
- Volunteers
- 353 people
- Sponsor
- Bracco Diagnostics, Inc
Focal Liver Lesions
Auxiliary Diagnosis of Liver Nodules Using cfDNA Whole-genome Signatures
As a prospective, multi-center study, GUIDER will recruit 400 liver nodules participants from different provinces and regions across China.
- Trial name
- GUIDER (NCT05393102)
- Testing
- No interventions
- Where
- 3 sites in China
- Volunteers
- 400 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Liver Neoplasms
A Trial on Contrast-enhanced Ultrasound Versus Conventional Ultrasound Guided Biopsy of Liver Neoplasms
The purpose of this study is to estimate the clinical value of contrast-enhanced ultrasound in percutaneous biopsy for liver occupied lesion.
- Trial name
- NCT02413437
- Testing
- CEUS guided biopsy, US guided biopsy, Ultrasound
- Where
- China
- Volunteers
- 2,088 people
- Sponsor
- Peking University Cancer Hospital & Institute
Known or Suspected Focal Liver Lesions
Efficacy and Safety of Primovist in Chinese Patients
Participants who had been diagnosed or suspected by doctors to have focal liver lesions that need further evaluation in order to make an accurate diagnosis.
- Trial name
- NCT00526188
- Testing
- Gadoxetic Acid Disodium (Primovist, BAY86-4873)
- Where
- 6 sites in China
- Volunteers
- 234 people
- Sponsor
- Bayer
Hepatocellular Carcinoma
Fusion Imaging Contrast-enhanced Ultrasound LI-RADS
CEUS LI-RASD apply to lesion visible at precontrast ultrasound but not the lesion invisible. Fusion imaging can use to invisible lesions at precontrast ultrasound in clinical practice.
- Trial name
- NCT04955119
- Testing
- Fusion imaging contrast-enhanced ultrasound
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Tianjin Third Central Hospital
Liver Neoplasms, Adenoma
Liver MRI With Primovist/Eovist in Pediatric Subjects Who Are Suspected or Have Focal Liver Lesions.
Medical records are reviewed to obtain information about the use of a MRI diagnostic imaging agent (contrast agent) called Primovist/Eovist in children older than 2 months and less than 18 years.
- Conditions
- Liver Neoplasms, Adenoma, Carcinoma, Liver Abscess
- Trial name
- NCT01043523
- Testing
- Gadoxetic Acid Disodium (Eovist, BAY86-4873)
- Where
- 9 sites in United States, Italy and 3 more
- Volunteers
- 52 people
- Sponsor
- Bayer
Hepatic Neoplasms
Identification of Hepatic Lesions
Patients with suspicion of primary or secondary hepatic malignancy in whom a radiological examination is needed in order to decide on the most appropriate treatment.
- Trial name
- NCT00307866
- Testing
- Resovist (BAY86-4884, SH U 555 A)
- Where
- 19 sites in Italy
- Volunteers
- 218 people
- Sponsor
- Bayer
Focal Nodular Hyperplasia of Liver, Toxic Liver Disease With Focal Nodular Hyperplasia
Contrast Enhanced Ultrasound For The Evaluation Of Focal Liver Lesions
The aim of the study is to assess the value of contrast enhanced ultrasound in the evaluation of de novo focal liver lesions in clinical practice, in a prospective multi-center design.
- Conditions
- Focal Nodular Hyperplasia of Liver, Toxic Liver Disease With Focal Nodular Hyperplasia, Liver Metastases
- Trial name
- HepFocUS (NCT01329458)
- Where
- 5 sites in Romania
- Volunteers
- 1,500 people
- Sponsor
- Societatea Romana de Ultrasonografie in Medicina si Biologie
Focal Liver Lesions, Focal Lesions in the Abdomen
Interventional Sonography Guided by Image Fusion
The purpose of this study is to register the precision of image fusion between live sonography and CT, MRI or PET/CT of liver lesions and other focal lesions in the abdomen.
- Trial name
- NCT00781924
- Testing
- biopsy
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hepatocellular Cancer
Effect of Pregabalin on the Postoperative Analgesia in RFA of Focal Lesions in the Liver
The study aimed to investigate the preemptive analgesia efficacy of of preemptive pregabalin for the postoperative pain management after radiofrequency ablation (RFA) of liver cancer.
- Trial name
- pregabalin (NCT03151213)
- Testing
- Pregabalin 150mg
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Sherief Abd-Elsalam
Liver Diseases
Contrast Enhanced Ultrasound Guidance Biopsy for the Diagnosis of Liver Tumors
The main purpose of this study is to compare contrast-enhanced ultrasound guided liver biopsy (CEUS-LB) with conventional ultrasound guided liver biopsy (US-LB) in the diagnosis of liver tumors developed on a background of…
- Trial name
- ConCLUDe (NCT03811431)
- Testing
- Contrast enhanced ultrasound guided liver biopsy
- Where
- Romania
- Volunteers
- 138 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Hepatocellular Carcinoma, Cholangiocarcinoma, Intrahepatic
Standardized CEUS Algorithms for Diagnosis of HCC - Prospective German Multicenter Study
Aim of this prospective national multicenter study is to improve standardization of contrast-enhanced ultrasound (CEUS) in the non-invasive diagnosis of hepatocellular carcinoma (HCC) in high-risk patients.
- Conditions
- Hepatocellular Carcinoma, Cholangiocarcinoma, Intrahepatic, Liver Cirrhosis, Liver Cancer
- Trial name
- ESCULAP (NCT03405909)
- Testing
- contrast enhanced ultrasound (CEUS), MRI, Histology
- Where
- Germany
- Volunteers
- 517 people
- Sponsor
- University Hospital Erlangen
Liver Cancer
[18F]FAPI PET/CT in Suspicious Focal Liver Lesions Without FDG Avidity
Fibroblast activation protein (FAP) is a serine protease that belongs to the dipeptidyl peptidase-IV (DPP-IV) family located in fbroblast membranes.
- Trial name
- NCT05806333
- Testing
- FAPI PET
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jilin University
Focal Liver Lesion
CT Image-assisted Detection Software for Focal Liver Lesions
To evaluate the safety and effectiveness of the developed and produced CT image-assisted detection software for focal liver lesions before being put into the market.
- Trial name
- MRMC (NCT06068413)
- Testing
- CT image-assisted detection software
- Where
- China
- Volunteers
- 376 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Liver Cirrhoses
Non-Invasive Characterization of Focal Liver Lesions in Liver Cirrhosis
This study aims to analyze non-invasive characterization focal liver lesions in patients with liver cirrhosis. The diagnostic accuracy and predictive value of non-invasive methods is studied.
- Trial name
- NICETIES (NCT03746210)
- Testing
- Standard diagnostic procedures
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital, Bonn
Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc)
Interventional AI-Human Collaboration for Liver Tumor Diagnosis
Recent advances in artificial intelligence (AI), particularly deep learning technology, have transformed medical imaging analysis.
- Conditions
- Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc), Hepatic Metastasis, Hepatic Hemangioma
- Trial name
- NCT07153783
- Testing
- AI-human collaboration for CE-CTs diagnosis
- Where
- China
- Volunteers
- 10,333 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Ultrasound
Prospective Multicenter Study on Clinical Application of Sonazoid in Liver Tumor
Sonazoid as a new generation of ultrasound contrast agent.This study based on the features of Sonazoid specific angiography and his mechanical index, the role of Sonazoidin in the differential diagnosis of benign and malignant…
- Trial name
- NCT04563897
- Volunteers
- 1,300 people
- Sponsor
- Chinese PLA General Hospital