Clinical trials: Focus
Postpartum Depression, Small for Gestational Age at Delivery
Happy Mother-Healthy Baby: An Anxiety-focused Early Prenatal Intervention
In the proposed study the investigators will develop an early prenatal preventive intervention targeting anxiety and conduct a randomized controlled trial in Pakistan to test its efficacy in reducing generalized anxiety disorder…
- Conditions
- Postpartum Depression, Small for Gestational Age at Delivery, Preterm Birth, Anxiety
- Trial name
- HMHB (NCT03880032)
- Testing
- Cognitive Behavioral Therapy Intervention for Anxiety
- Where
- Pakistan
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Brain Injuries, Focal
The Impact of Self-processing on Mental Time Travel
Mental time travel (MTT) refers to the ability to project oneself backward into the past or forward into the future to envision past and future events.
- Trial name
- NCT06823193
- Testing
- Mental Time Travel task, Age Estimation control task, Lifeline task
- Where
- Italy
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention, Heart Disease
Social Work Intervention Focused on Transitions
In response to Program Announcement (PA)-09-164, "NIH Exploratory/Developmental Research Grant Program (R21) a randomized pilot study testing the efficacy of SWIFT: Social Work Intervention Focused on Transitions among at-risk…
- Conditions
- Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention, Heart Disease, Diabetes, Hypertension
- Trial name
- SWIFT (NCT02232126)
- Testing
- SWIFT home intervention
- Where
- 2 sites in United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Cataract, Cataract Senile
Impact of a Novel Extended Depth of Focus Intraocular Lens on Visual and Lifestyle Enhancement
The introduction of presbyopia-correcting intraocular lenses (PC-IOLs) has provided cataract and refractive surgeons the ability to provide patients with a wider range of visual success and spectacle independence post-cataract…
- Conditions
- Cataract, Cataract Senile, Presbyopia
- Trial name
- NCT04570579
- Testing
- Vivity Extended Depth of Focus Intraocular Lens
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Alanna Nattis, DO
Quality of Life, Aging
Upper Versus Lower Body Resistance Exercise in Older Adults
TITLE: Relation between focused resistance training and its effect on cognitive performance and functional Independence of institutionalized elderly.
- Trial name
- NCT03831373
- Testing
- Physical exercise
- Where
- Spain
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Vigo
Gingival Recession, Localized
Cyanoacrylate Use in Free Gingival Graft
Present study aims to reveal the effects of cyanoacrylate application at the recipient bed and the donor site in free gingival graft surgery on the healing parameters and patient-based outcomes.
- Trial name
- NCT04854902
- Testing
- Free gingival graft, Cyanoacrylate, Suture
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Biruni University
Posttraumatic Stress Disorder
The Effectiveness of CFT for Reducing Self-criticism in Patients With Complex PTSD: a Single-case Experimental Study
PTSD is a mental disorder including psychological symptoms related to severe traumatic event(s). PTSD can negatively affect people's functioning in several life domains.
- Trial name
- NCT05791760
- Testing
- Compassion-focused therapy (CFT) for complex PTSD
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Twente
Focal Segmental Glomerulosclerosis (FSGS)
Evaluation of the Pharmacokinetics and Safety of Inaxaplin in Participants With Mild or Moderate Hepatic Impairment
The purpose of this study is to evaluate the pharmacokinetics, safety and tolerability of Inaxaplin (IXP) in participants with mild or moderate hepatic impairment and in matched healthy participants.
- Trial name
- NCT06529796
- Testing
- IXP
- Where
- 3 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Vertex Pharmaceuticals Incorporated
Conditions: None. Focus: Understanding the Obesogenic Potential of Fructose Containing Sugars
A Comparison of the Neurocognitive and Metabolic Effects of Fructose, Glucose, High Fructose Corn Syrup and Sucrose at Normal Population Consumed Levels in Adults Ages 20-60 Years Old
The purpose of this study is to investigate the acute and chronic effects of consumption fructose containing sugars and glucose in a real word setting when consumed in a manner and amount typical in the American diet.
- Trial name
- NCT02278042
- Testing
- Beverage Consumption
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Rippe Lifestyle Institute
Other Conditions That May Be A Focus of Clinical Attention
Genetic Basis for Variation in the Renal Elimination of Metformin
The current study is part of a large multi-investigator grant to look at the pharmacogenetics of a number of membrane transporters.
- Trial name
- NCT00187720
- Testing
- Metformin
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Erectile Dysfunction
Autologous PRP and Focal Shock Waves for Erectile Dysfunction
The goal of this clinical trial is to learn if Platelet-rich plasma (PRP) combined with Shock-wave therapy (SWT) works to treat moderate or mild to moderate erectile dysfunction.
- Trial name
- NCT06433596
- Testing
- Platelet-rich plasma, Shock waves therapy
- Where
- Spain
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Elexial Research Limited
Psychosis, Psychosis-Related PTSD
Attachment-focused iMAgery Therapy for PSychosis (A-iMAPS)
The relationships we have in childhood affect how we relate to others across our life, including how safe or secure we feel. If our caregivers do not meet our needs well enough in childhood, this can lead to an 'insecure…
- Trial name
- NCT05042050
- Testing
- A-iMAPS
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Social Climate, Compassion
Improving Social Climate in Secure Settings With a Compassion Focused Staff Intervention
This study evaluates the effectiveness of a Compassion Focused Staff Support (CFSS) intervention in improving the social climate of correctional and forensic psychiatric institutions.
- Conditions
- Social Climate, Compassion, Critical Incident, Staff Support
- Trial name
- NCT07135518
- Testing
- Compassion Focused Staff Support, CFT Workshop
- Where
- Switzerland
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University Psychiatric Clinics Basel
Healthy Volunteers
Sensor Off Study Using a Nellcor USB Pulse Oximetry Monitor Interface Cable
The purpose of this study is to validate that the device posts a Sensor-Off message within the time frame stated in the proposed claims.
- Trial name
- NCT02265783
- Testing
- Nellcor USB Pulse Oximeter Monitor Interface Cable
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Exercise Motivation
Motivation for Exercise: A Mood-Based Focus
The goal of this study is to assess the effects of an exercise-related video on exercise motivation and adherence. Specifically, the researchers are studying whether an exercise-for-mood video increase levels of exercise…
- Trial name
- NCT06706180
- Testing
- Exercise for Mood video, Exercise for Fitness video
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Daytime Sleepiness
Community-Level Daytime Sleepiness: Social-Environmental Determinants, Consequences, and Impact of Sleep Apnea
The purpose of this study is to examine daytime sleepiness in a community context. This includes examining sleepiness in a large sample in terms of social/behavioral/environmental predictors and health-related outcomes, as well…
- Trial name
- NCT04176042
- Testing
- Track 1, Track 2
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Morbid Obesity, Type2 Diabetes
Elucidating the Mechanism of Remission of Type 2 Diabetes in Morbid Obese Patients After Bariatric Surgery
The main aim of this study is to elucidate the mechanism of the remission of type 2 diabetes in the morbid obese patients after laparoscopic sleeve gastrectomy.
- Trial name
- NCT03038373
- Testing
- Laparoscopic Sleeve Gastrectomy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Dasman Diabetes Institute
Food Insecurity, Pregnancy Related
Infant Feeding in French Guiana
This is a comparative, observal study among the population of pregant women who participated to the study "Nutri Pou Ti Moun" on food insecurity during pregnancy in French Guiana
- Trial name
- ANJE Nutri (NCT06528275)
- Testing
- Health promotion intervention
- Where
- French Guiana
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
Dystonia, Healthy
Brain Anatomy in Dystonia
This study will use high-resolution magnetic resonance imaging (MRI) to look for subtle differences in brain anatomy between patients with focal hand dystonia (also called writer s cramp) and healthy normal volunteers.
- Trial name
- NCT00031369
- Where
- United States
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
redOx Metabolism
Analyses of Bone Marrow and Blood Samples From Healthy Volunteers: Focus on the redOx Metabolism
Oxidative stress is defined by an excess of reactive oxygen species (reactive oxygen species or ROS) in cells. ROS are essential to cell life (proliferation, differentiation), including kinase activity via inhibition of…
- Trial name
- HEALTHOX (NCT02789839)
- Testing
- Blood test, Medullar test
- Where
- France
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
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