Clinical trials: Food Allergies
Food Allergy
Basophile Activation Testing (BAT) in Hazelnut Allergy (Hazelnut BAT Study)
The proposed study intends to compare the outcome of food challenge in hazelnut allergic patients with the outcome of basophile activation tests using hazelnut extract and components.
- Trial name
- NCT03079206
- Testing
- Food challenge, skin testing, blood sampling
- Where
- Switzerland
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Atopic Dermatitis, Eczema
Daily Use of Lipikar Balm AP From Birth in Infants at High Risk of Developing Atopic Dermatitis
There is a lack of prospective scientific data on the regular use of moisturizers in patients at risk of developing atopic dermatitis.
- Conditions
- Atopic Dermatitis, Eczema, Asthma, Food Allergies
- Trial name
- NCT01577628
- Testing
- Lipikar Balm AP
- Where
- 4 sites in United States, Canada
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Peanut Allergy
High and Low Dose Oral Peanut Immunotherapy - Comparison of Efficacy and Safety
In this trial the investigators aim to assess the effectiveness and safety of oral immunotherapy with peanut protein in high and low dose (300mg versus 150mg) in children with peanuts allergy.
- Trial name
- NCT04415593
- Testing
- High dose of peanuts, Low dose of peanuts
- Where
- Poland
- Volunteers
- 44 people
- Sponsor
- Medical University of Warsaw
Esophagitis, Eosinophilic
The Potential Role of Compounds Derived From Ultra-processed Foods in Pathogenesis of Eosinophilic Esophagitis
Eosinophilic esophagitis (EoE) is a chronic antigen-mediated inflammatory disease of the esophagus that affects both children and adults.
- Trial name
- NCT06093204
- Testing
- Dietary evaluation
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Federico II University
Digestive Health, Gastrointestinal Health
The Effects of Oral Fructanase Administration on Gastrointestinal Symptoms After Inulin Challenge in Healthy Adults
The carbohydrate inulin (from chicory root) is a healthy prebiotic ingredient found in dietary supplements and fortified foods (Nagy et al).
- Conditions
- Digestive Health, Gastrointestinal Health, FODMAP Intolerance, Food Sensitivity
- Trial name
- NCT06628869
- Testing
- Fructanase
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- BIO-CAT, Inc.
Shellfish Allergy
Safety of Chitosan as Wine Fining Agent in Shrimp Allergic Patients
Chitosan, the main component of the exoskeletons of crustaceans, mollusks and cephalopods, has been used as a fining agent in wines. However, its safety among patients allergic to shellfish has never been evaluated.
- Trial name
- SWAP (NCT02151279)
- Testing
- Chitosan as wine fining agent, Control
- Where
- 2 sites in Portugal
- Volunteers
- 15 people
- Sponsor
- Universidade do Porto
Food Allergy, Wheat Allergy
Evaluation of Potential Allergenicity of New Wheat Varieties
The goal of the study is to determine accurate blood test levels that can predict whether or not subjects are truly allergic to certain foods.
- Trial name
- NCT02341040
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Food Allergy in Children
Sustained Unresponsiveness (SU) to Cashew Nut Protein Following Oral Allergen-Specific Immunotherapy
This study is a long-term follow-up of participants from the randomized controlled trial (RCT) "Efficacy of Cashew Nut Protein Immunotherapy: A Protocol of a Single-Center Randomized Controlled Trial in the Pediatric Population"…
- Trial name
- NCT07158619
- Testing
- OIT with cashew nut protein
- Where
- Poland
- Volunteers
- 39 people
- Sponsor
- Medical University of Warsaw
Allergy
Cetirizine Chewable Bioequivalence and Food Effect Study
The purpose of this study is to determine and compare the amount of study drug that gets into your blood after the administration of each of the three formulations of cetirizine under different conditions.
- Trial name
- NCT03772158
- Testing
- Cetirizine 10mg, Cetirizine 10 mg
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division
Food Hypersensitivity, Shellfish Allergy
Recombinant Tropomyosin- and Hemocyanin-Specific IgE in Children With Suspected Shrimp Allergy
This study will evaluate whether blood tests that measure IgE antibodies to two shrimp proteins, tropomyosin and hemocyanin, can help diagnose shrimp allergy in children.
- Trial name
- NCT07501325
- Testing
- Oral Food Challenge (OFC), Skin Prick Test, Recombinant Tropomyosin- and Hemocyanin-Specific IgE Measurement
- Where
- Vietnam
- Volunteers
- 129 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Rhinitis, Food Allergy
Oral Allergy Syndrome (OAS): a Pilot Study to Evaluate a Clinical Questionnaire as a Diagnostic Tool
An increasing number of people have an allergy to birch pollen, which manifests itself as Springtime hayfever. Some will also have cross-reactions to fruits, vegetables and nuts, a condition known as Oral Allergy Syndrome (OAS).
- Trial name
- NCT00427479
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Atopic Dermatitis (Eczema)
The Effects of an Oral Prebiotic and an Oral Synbiotic Supplement in Combination With a Topical Lotion and Soap On Eczema
The purpose of this study is to examine the effects of 2 dietary supplements (an oral prebiotic and an oral synbiotic) in combination with a topical lotion, and an unscented soap on eczema severity, various skin measures (such as…
- Trial name
- NCT07041892
- Testing
- Prebiotic Supplement + Synbiotic Supplement + Topical Lotion + Unscented Soap
- Where
- Poland
- Volunteers
- 34 people
- Sponsor
- Codex Labs Corporation
Peanut Allergy
Safety of MOON101 for the Treatment of Peanut Allergy
The goal of this open-label, single escalating dose study in 3 sequential groups: adults, adolescents, and children with peanut allergy is to assess the safety of MOON101. The main question it aims to answer is: 1.
- Trial name
- SURVEYOR (NCT07580898)
- Testing
- Dose A, Dose B, Dose C
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Moonlight Therapeutics, Inc.
Non-celiac Gluten Sensitivity; Adolescents
Non Celiac Gluten Sensitivity, DBPCFC in Adolescents
In a population based on healthy adolescents we will conduct a double blind placebo controlled food challenge (DBPCFC) with cross-over to identify patients with NCGS as recommended by the socalled Salerno criteria.
- Trial name
- NCT04639921
- Testing
- positive test followed by gluten-free diet
- Where
- Denmark
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Peanut Hypersensitivity, Food Hypersensitivity
Peanut Epicutaneous Phase II Immunotherapy Clinical Trial
Food allergy occurs when the immune system reacts against foods. The immune system is the part of the body that protects us from illness and germs, but it can also cause allergies.
- Conditions
- Peanut Hypersensitivity, Food Hypersensitivity, Hypersensitivity, Hypersensitivity, Immediate
- Trial name
- NCT01904604
- Testing
- Low-dose DBV712 Viaskin® Patch, High-dose DBV712 Viaskin® Patch
- Where
- 5 sites in United States
- Volunteers
- 75 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Food Allergy
Intranasal Diagnostics in Food Allergy: a Feasibility Study
The investigators will conduct low-dose intranasal allergen challenges on children/adolescents with a diagnosis of food allergy to egg/cow's milk/soya/wheat/peanut.
- Trial name
- INDY (NCT02159833)
- Testing
- Intranasal challenge with active substance (food protein)
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- Imperial College London
Peanut Allergy
Oral Desensitization to Peanut in Peanut Allergic Children and Adults Using CPNA Peanut OIT Safety Follow-On Study
This is a multi-center, open-label, follow-on study to gather additional information on the safety and tolerability of oral desensitization with CPNA in the subjects who participated in ARC001.
- Trial name
- NCT02198664
- Testing
- AR101 - Peanut protein capsule
- Where
- 8 sites in United States
- Volunteers
- 47 people
- Sponsor
- Aimmune Therapeutics, Inc.
Peanut Allergy
Pinpoint Trial: Prebiotics IN Peanut Oral ImmunoTherapy
The purpose of this research is to gather information on the safety and efficacy of using a prebiotic as an adjunctive therapy to peanut oral immunotherapy.
- Trial name
- NCT05138757
- Testing
- Prebiotic
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Chicago
Irritable Bowel Syndrome
Irritable Bowel Syndrome and Food Sensitivity
The primary objective of the clinical trial portion of this study is to assess whether an individualized dietary plan based on a commercial food sensitivity assay provides specific benefit in a randomized controlled trial in…
- Trial name
- NCT02186743
- Testing
- Personalized Dietary Advice
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Yale University
Cow's Milk Protein Allergy (CMPA)
TeriFort 1+ Study: Efficacy and Safety of an Extensively Hydrolyzed Formula in the Management of Cow's Milk Protein Allergy in Young Children: A Prospective, Single-Arm Interventional Study (TeriFort 1+)
This study aims to evaluate the clinical effect, as reported by physicians, of an extensively hydrolyzed formula in young children aged 1~3 years with diagnosed with or highly suspected CMPA in a real-world clinical practice…
- Trial name
- NCT07855796
- Testing
- Diagnosed with or highly suspected CMPA: Extensively Hydrolyzed Formula intervention
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Teyi Yinuo Health Technology Co., Ltd.