Clinical trials: Food Effect
Healthy Participants, IBD (Inflammatory Bowel Disease)
A Phase I Study of HW201877 in Healthy Subjects
This is a Phase I, randomized, double-blind, placebo-controlled study to assess the safety, tolerability, pharmacokinetic (PK), pharmacodynamic (PD), and food effect (FE) of HW201877 in healthy subjects following (1) a single…
- Trial name
- NCT07373457
- Testing
- HW201877 capsules
- Where
- China
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Wuhan Humanwell Innovative Drug Research and Development Center Limited Company
Healthy Participants
A Study to Assess the Bioavailability of a New Tablet Formulation of Minzasolmin and the Effect of Food in Healthy Participants
The purpose of the study is to estimate the relative bioavailability of a new minzasolmin tablet formulation versus reference 'granules in capsule' formulation in healthy participants and to evaluate the effect of food with the…
- Trial name
- NCT06533475
- Testing
- Minzasolmin tablet formulation under fasting condition, Minzasolmin Granules in capsule under fasting condition, Minzasolmin tablet formulation under fed condition
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- UCB Biopharma SRL
Biomarkers of B-vitamin Status and Gut Microbiome Composition
Effect of a Food Intervention With a Prebiotic Alone or Combined With B-vitamins on Gut Microbiota Diversity, Inflammation and Mental Health Outcomes in Older Adults (GutFood)
Ageing is associated with changes in gut microbiota composition, increased inflammation, and a greater risk of poor mental health outcomes.
- Trial name
- NCT07592975
- Testing
- Inulin and B-vitamins, Inulin
- Where
- United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Food
Effect of Bran Fiber Type on Subjective and Objective Measures of Appetite
The objective of this study is to determine the satiety value of different bran fibers on appetite \& subsequent food intake with acute consumption. Satiety will be measured subjectively by visual analogue scales (VAS).
- Trial name
- NCT01560000
- Testing
- Dietary fiber
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Healthy Participants
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Food Effect of JZP047 in Healthy Participants
This is a Phase 1, double-blind, sponsor-unblinded, randomized, placebo-controlled study designed to characterize the safety, tolerability, and PK of JZP047 in healthy participants following single-ascending doses of study…
- Trial name
- NCT07377539
- Testing
- JZP047
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Jazz Pharmaceuticals
Healthy Participants
Food-effect Study of Ammoxetine Hydrochloride Enteric-coated Tablets
This study is a single-center, randomized, open-label, two-period crossover design to evaluate the effect of food on the pharmacokinetic profile of ammoxetine hydrochloride enteric-coated tablets.
- Trial name
- NCT07508501
- Testing
- Ammoxetine hydrochloride enteric-coated tablets
- Where
- China
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Metabolic Syndrome
High Resistant Starch (RS) Cookies and Appetite Control
Evaluation of the effect of ingestion of high RS-cookies prepared from high amylose corn starch on food intake and appetite control of a cohort of healthy students.
- Trial name
- RS (NCT02323828)
- Testing
- High RS cookies
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Asthma
A Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of AZD9898
In this integrated, multi-part, Phase I study, the safety, tolerability, food effect, pharmacokinetic (PK) and pharmacodynamic (PD) properties of single and repeated doses of AZD9898 will be investigated.
- Trial name
- NCT03140072
- Testing
- AZD9898
- Where
- 2 sites in United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Depressive Disorder and Anxiety Disorders
Relative Bioavailability and Food Effect Study for GSK163090 in Healthy Male and Female Volunteers
The study will consist of a screening period, 3 treatment periods and a post-treatment follow-up. In each of the 3 treatment periods, subjects will receive a single oral dose of GSK163090 in the fed or fasted state, followed by a…
- Trial name
- NCT00536679
- Testing
- GSK163090 capsule, fasted, GSK163090 Tablet, fasted, GSK163090 Tablet, fed
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy
Pharmacokinetics and Food Effect of Sarpogrelate HCl CR Formulation in Comparison to Immediate-release Formulation
The purpose of this study is to evaluate the pharmacokinetics of sarpogrelate controlled-release formulation (CR) in comparison to immediate-release formulation (IR) and Food effect on the pharmacokinetics of sarpogrelate CR.
- Trial name
- NCT01841086
- Testing
- Anplag, UI03SPG300CT
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Korea United Pharm. Inc.
Safety
Single Dose and Multiple Dose Escalation Trial of an Oral Formulation of MRX-4
A phase one study of the safety, tolerability, and pharmacokinetics of a new oxazolidinone antibiotic. Cohorts of healthy adults (female and male) will participate in: single dose escalation study of increasing doses of MRX-4…
- Trial name
- NCT03033342
- Testing
- Oral single doses of MRX-4, Oral multiple doses of MRX-4, MRX-4 co-administered with omeprazole
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- MicuRx
Healthy
A Comparative Bioavailability and Pharmacokinetic Study of TNX-102 2.4 mg and Cyclobenzaprine 5 mg Tablets in Healthy Adults.
The trial is designed to assess the safety and tolerability of TNX-102 2.4 mg and to compare the bio-availability of TNX-102 2.4 mg and cyclobenzaprine 5 mg tablets under fasting or fed conditions.
- Trial name
- NCT01490788
- Testing
- Treatment A, Treatment B, Treatment C
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tonix Pharmaceuticals, Inc.
Obesity, Hyperlipidemia
Effects of Dietary Antioxidants on Cardiovascular Risk Factors
The aim of the Antioxidant Study was to compare the efficacy of foods naturally rich in antioxidants with that of antioxidants in a pill form on markers of inflammation and plasma cholesterol in healthy adults at risk of…
- Conditions
- Obesity, Hyperlipidemia, Hypertension
- Trial name
- NCT00756405
- Testing
- Antioxidant diet, Antioxidant supplement
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Christopher Gardner
Eating Behavior, Obesity
Caffein Consumption and Response Inhibition
With the abundance of energy-dense foods that are designed for ease of consumption in the current environment, it is of importance to better understand the factors that may undermine the control of energy intake at healthy…
- Trial name
- NCT01815203
- Testing
- Caffeine
- Where
- Sweden
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Healthy Volunteer
A Study on the Effect of Food on the Pharmacokinetics of RO5428029 in Healthy Volunteers
This open label, two period, crossover study will evaluate the safety and the effect of food on the pharmacokinetics of RO5428029 in healthy volunteers.
- Trial name
- NCT01345942
- Testing
- RO5428029
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Idiopathic Pulmonary Fibrosis
Single and Multiple Dose Safety, Tolerability, PK and Food Effect Study of HEC585 in Healthy Male and Female Subjects
The Safety, Tolerability Pharmacokinetic and Food Effect Study of HEC585 in Healthy Male and Female Subjects
- Trial name
- NCT04512170
- Testing
- HEC585
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Sunshine Lake Pharma Co., Ltd.
Deficiencies Micronutrient, Nutrition Disorders
Effect of Consuming Vitamin A-fortified Sugar on Serum Retinol Levels in Children
The increase in vitamin A deficiency (<20 mcg/dL) among children under five in Colombia (2010-2015) is a public health problem (27.3%).
- Trial name
- NCT07860060
- Testing
- white sugar fortified with retinol, refined white sugar for culinary use
- Where
- Colombia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Universidad del Valle, Colombia
Nutrition, Healthy
Effect of Transtheoretical Model Based Nutrition Education on Sustainable Nutrition Behavior in Adolescents
The aim of this intervention study is to evaluate the effect of sustainable nutrition education based on the Transtheoretical Model (TTM) on adolescent behavior.
- Trial name
- NCT06583499
- Testing
- Sustainable nutrition education based on the transtheoretical model
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Intrahepatic Cholangiocarcinoma
HMPL-453 Food Effect and PPI Study in Healthy Volunteer Study
A Phase 1, Open-label, 4-Period, Randomized 6-Sequence Study to Evaluate the Effect of Food and Rabeprazole, a Proton Pump Inhibitor, on the Pharmacokinetics of HMPL-453 in Healthy Volunteers
- Trial name
- NCT05930119
- Testing
- HMPL-453, Rabeprazole
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hutchmed
Dermis Density, Wrinkles
The Effect of 16-week Dietary Intake of Food Supplements Containing Collagen and MSM on Skin
The aim of the study is to compare the effects of multiple-dose 16 weeks daily dietary supplementation with 5 g or 3 g of collagen in combination with 1 g or 1.5 g of MSM and 80 mg vitamin C (see 1.2.
- Conditions
- Dermis Density, Wrinkles, Dermis Thickness, Skin Texture
- Trial name
- TO-COSKIN3 (NCT06755892)
- Testing
- ColMSM-HL, ColMSM-LH, ColMSM-LL
- Where
- Slovenia
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- VIST - Faculty of Applied Sciences
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