Clinical trials: Food Intolerance
Functional Bowel Disorder, Irritable Bowel Syndrome
The 5Ad Diet for Functional Bowel Disorders
The goal of this randomised controlled trial (RCT) is to compare the efficacy of the newly developed 5Ad diet against the widely researched low fermentable oligo-, di-, monosaccharide and polyols (FODMAP) diet in reducing…
- Conditions
- Functional Bowel Disorder, Irritable Bowel Syndrome, Food Intolerance, Food Intolerance Syndromes
- Trial name
- NCT06338189
- Testing
- The 5Ad Diet, The Low FODMAP Diet
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Suffolk
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Gluten Intolerance
Development of a Celiac Safe Food Additive
The goal of this clinical trial was to investigate if intestinal deamidation of gliadin from wheat bread could be hindered by adding a E304i/zinc additive.
- Trial name
- NCT06005376
- Testing
- Breakfast rolls consisting of wheat flour with and without a E304i/zinc additive
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chalmers University of Technology
Non-coeliac Gluten Sensitivity
Effect of AN-PEP Enzyme on Gluten Digestion in Gluten Sensitive Individuals
In this trial, the effect of a low and a high dose AN-PEP will be investigated in gluten sensitive individuals. Volunteers receive a breakfast with background (0.5 g) gluten.
- Trial name
- AN-PEP-03 (NCT02060864)
- Testing
- AN-PEP
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- DSM Food Specialties
Pre-diabetes
Effects of a Dietary Supplement Containing L-Arabinose and Trivalent Patented Food-source of Chromium on Blood Glucose and Insulin
This study was designed to examine changes in capillary blood glucose and venous insulin levels after a 70 gram oral sucrose challenge with and without simultaneous consumption of a dietary supplement containing L-Arabinose and a…
- Trial name
- L-Arabinose (NCT01107431)
- Testing
- L-Arabinose and Chromium, Sucrose without dietary Supplement
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Integrative Health Technologies, Inc.
Postprandial Glycemia, Postprandial Insulinemia
A Human Clinical Trial Evaluating the Effect of MealShape™ on Blood Glucose Level Following Consumption of Standard Meal
The purpose of the study is to evaluate the effect of MealShape, a Ceylon cinnamon extract (Cinnamomum zeylanicum) on blood glucose and insulin response after consumption of a standard meal composed of white bread, in healthy…
- Trial name
- NCT02074423
- Testing
- MealShape cinnamon extract
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Dialpha
Intervention, Food Allergy
Healthy Meals: A Restaurant-based Study to Promote Healthy and Allergy Adapted Diet
This study evaluates the effect of a multicomponent intervention applied to restaurant staff about training and nutritional quality of menu improvement, in order to promote a healthy diet and a better management of allergies and…
- Conditions
- Intervention, Food Allergy, Food Preferences, Food Intolerance
- Trial name
- HealthyMeals (NCT03826576)
- Testing
- Multicomponent intervention
- Where
- Spain
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Glucose Intolerance, Aortic Stiffness
Healthy Aging Through Functional Food
The purpose of this study is to determine whether dietary inducers of glyoxalase 1 are effective in improving metabolic and vascular health.
- Conditions
- Glucose Intolerance, Aortic Stiffness, Vasodilation
- Trial name
- HATFF (NCT02095873)
- Testing
- Glyoxalase 1 (Glo1) inducer
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Warwick
COW'S MILK ALLERGY
Polymerized Beta-lactoglobulin Comparative Immunoreactivity
Bovine β-lactoglobulin (Bos d 5) is an allergen from cow's milk with relevance to human health. We employed β-lactoglobulin polymerized using microbial transglutaminase as a model of study to identify whether protein…
- Trial name
- ImmuneBLG (NCT01589731)
- Where
- Brazil
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Allergy, IBS
24 Hrs Histamine Profile in Healthy Persons and Patients With Food Intolerance
Over 24 hrs serum and plasma samples were collected every 3 hrs. With this a day histamine profile was created. 15 healthy persons with 20 patients with a high level of IgE in serum and 20 patients with afflictions but no high…
- Trial name
- NCT02293343
- Testing
- blood profile
- Where
- Germany
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Food Sensitivity
Effects of Different Polyphenol-containing Beverages on the Immune System and on Muscular Growth Factors
In this research project, the effect of different polyphenol-containing beverages with varying alcohol content of < 0.4 vol% on immune function as well as muscular growth factors will be investigated
- Trial name
- NCT04983420
- Testing
- non-alcoholic Pilsner, non-alcoholic wheat beer, apple spritzer
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Food Intolerance, Celiac Disease
"Gluten Friendly" Treatment in Celiac Disease
A PROSPECTIVE, double blind, placebo-controlled trial
- Trial name
- GLUFR (NCT03137862)
- Testing
- Gluten free bread, Gluten friendly bread 3g/day, Gluten friendly bread 6g/day
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Casa Sollievo della Sofferenza IRCCS
Irritable Bowel Disease
Effects of Fasting and Hydro Colon Therapy Plus Probiotics on GI Microbiota in Intolerances and Irritable Bowel Syndrome
Consequences of Colon Hydrotherapy plus probiotic intervention on composition of GI microbiota and well being are analysed in subjects claiming GI inconveniences due to Irritable Bowel Syndrome or food intolerances.
- Trial name
- MicFFGAH2013 (NCT02372201)
- Testing
- Hydro Colon Therapy plus probiotic
- Where
- Austria
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Appetitive Behavior, Individual Difference
The Influence of Fat Perception on Satiety From Consumption of Reduced Fat Snacks
The present study aims to investigate the effect of fat level and fat type of a snack on self-reported satiety and associated biomarkers. The relevant individual differences will also be investigated.
- Conditions
- Appetitive Behavior, Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT03585920
- Testing
- Expanded Corn Snack
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Reading
Pre-diabetes
ELFI Health (e-Health for Empowerment by Lifestyle, Food Advice and Interaction)
In the present study the investigators will examine whether people living with prediabetes benefit from an e-health lifestyle intervention of three months.
- Trial name
- ELFI (NCT06236334)
- Testing
- ELFI lifestyle intervention
- Where
- Netherlands
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- TNO
Irritable Bowel Syndrome, Food Sensitivity
Confocal Laser Endomicroscopy to Determine Influence of Food Antigens on Mucosal Integrity
Irritable bowel syndrome (IBS) is mainly associated with food intolerance and presents a particular challenge in gastrointestinal practice.
- Conditions
- Irritable Bowel Syndrome, Food Sensitivity, Healthy Controls
- Trial name
- RDS_CLE (NCT05056610)
- Testing
- food antigens on duodenal mucosa
- Where
- Germany
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Food Allergy, Food Hypersensitivity
Mucosal IgE to Improve Diagnosis of Food Allergy and Food Hypersensitivity
Aim of the study is to improve the diagnosis of food allergy and hypersensitivity. Intestinal homogenates will be used to determine total IgE, specific IgE, tryptase, histamine and inflammation parameters (IFNgamma, TNFalpha).
- Trial name
- NCT05259826
- Testing
- biopsy sampling
- Where
- Germany
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Individual Difference, Food Sensitivity
Investigation of the Perception of Protein Fortified Foods and Beverages
This study aims to investigate whether protein fortification of foods and beverages causes mouthdrying and mucoadhesion and whether this is influenced by age and saliva flow.
- Conditions
- Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT03798730
- Testing
- Solid Model, Liquid Model
- Where
- United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Reading
Inflammatory Bowel Diseases, Quality of Life
Effect of Probiotic Administration on Patients With Inflammatory Bowel Disease
The study is a single-center, randomized, single-blinded, controlled trial conducted at ZHUMC's endoscopy unit. It aims to assess the short-term effects of probiotic administration on disease course, quality of life, and…
- Conditions
- Inflammatory Bowel Diseases, Quality of Life, Food Intolerance, Flare Up
- Trial name
- NCT06392061
- Testing
- Trilac
- Where
- Lebanon
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lebanese University
Gastric Emptying, Diabetes Mellitus
The Effect of Natural Food Flavourings on Gastrointestinal and Cardiovascular Physiological Responses.
The purpose of this study is to determine whether 3 g cinnamon was sufficient to delay the gastric emptying rate of a high-fat solid meal and subsequently reduce postprandial blood glucose and lipid responses, oxidative stress…
- Trial name
- CinnGastEmpt (NCT01350284)
- Testing
- Cinnamon
- Where
- Ireland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Limerick