Clinical trials: Food Labeling
Effect of Food
Phase I, Open Label,Crossover Food-Effect and Absolute Bioavailability Study of WCK2349 and WCK771 in Healthy Adult Human Volunteers
This study is aimed to ascertain the effect of food on pharmacokinetics of WCK 2349 and determine the absolute bioavailability of WCK 2349 1000 mg (oral, QD dose) with respect to WCK 771 800 mg (intravenous, QD dose).
- Trial name
- NCT01875939
- Testing
- Oral WCK2349, IV WCK771
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Wockhardt
Healthy
M7583 Relative Bioavailability of Tablet Compared to Powder-in-capsule
This is a Phase I study consisting of 2 parts: Part 1 aims to investigate the relative bioavailability of tablet formulation (test treatment) and Powder in capsule (PiC) formulation (reference treatment) of M7583 under fasted…
- Trial name
- NCT03297983
- Testing
- M7583
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Merck KGaA, Darmstadt, Germany
Healthy Adult Subject
A Relative Bioavailability and Food Effect Study of HDM1002 in Healthy Subjects
The main purpose of this study is to evaluate the effect of formulation on relative bioavailability of HDM1002, and the food effect on pharmacokinetics of HDM1002.
- Trial name
- NCT06608329
- Testing
- HDM1002
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
Healthy
Drug Interaction Study of MGL-3196 With Pioglitazone
The purpose of this study is to determine whether the single-dose pharmacokinetics (AUC) of pioglitazone are affected by chronic dosing with MGL-3196 100 mg/day in healthy subjects.
- Trial name
- NCT04671056
- Testing
- MGL-3196, Pioglitazone 15mg
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Madrigal Pharmaceuticals, Inc.
Nutrition Labeling, Tax Policy
Supermarket Labelling and Taxation Study
Participants will be assigned to one of four conditions: (i) nutrient warning labelling and no taxation, (ii) nutrient warning labelling and taxation, (iii) current traffic light labelling and taxation or (iv) a control condition…
- Trial name
- NCT07339982
- Testing
- Labelling, Taxation
- Where
- United Kingdom
- Volunteers
- 829 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Obesity, Overweight
A Cafeteria Based Study of Weight Gain Prevention
The dramatic rise in overweight and obesity during the past several decades can be explained by environmental changes that foster increased energy intake and decreased energy expenditure.
- Trial name
- Cafeteria (NCT00573482)
- Testing
- REDE, control
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Infection, Human Immunodeficiency Virus
Bioequivalence Study of Fixed Dose Versus Single Entities of Dolutegravir and Lamivudine
This study aims to compare the bioequivalence of two experimental fixed dose combination (FDC) tablets versus single entity products of dolutegravir (DTG) and lamivudine (3TC) in healthy adult subjects.
- Trial name
- NCT03078556
- Testing
- Dolutegravir, Lamivudine, Dolutegravir + Lamivudine FDC Formulation 1
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Healthy Volunteers
A Study of the Safety, Tolerability, and Bioavailability of Orally Administered Venglustat in Healthy Adult Participants
The purpose of this study is to assess the effect of food on the bioavailability of venglustat and to assess the relative bioavailability of venglustat tablet swallowed whole with water versus a tablet chewed and then swallowed…
- Trial name
- NCT06418620
- Testing
- Venglustat
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Sanofi
Complement-mediated Hemolytic Diseases
Effect of Food of NTQ5082 in Healthy Subjects
NTQ5082 capsule is a small molecule CFB factor inhibitor. The study is a randomized, open label, two sequence, two period, double crossover-design phase 1 clinical trial to evaluate the food effect on PK after a single oral…
- Trial name
- NCT06558656
- Testing
- NTQ5082 capsule
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nanjing Chia-tai Tianqing Pharmaceutical
Type II Diabetes Mellitus
Study to Evaluate the Food Effect on Pharmacokinetics Profile and Safety of CKD-393
Study to evaluate the food effect on pharmacokinetic profiles and safety of CKD-393 in healthy volunteers
- Trial name
- NCT05274880
- Testing
- CKD-393
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Healthy Volunteers
A Study Comparing the Pharmacokinetics and Palatability of Two Candidate Pediatric Powder-for-Oral-Suspension Formulations of Maribavir to the Current Maribavir Tablet Formulation Administered in Healthy Adult Participants
The Purpose of this study is to assess the relative bioavailability, dose proportionality, the impact of food on the rate and extent of absorption, palatability of the selected pediatric formulation of maribavir and the safety…
- Trial name
- NCT04131556
- Testing
- Maribavir
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shire
Biological Availability
Relative Bioavailability of Sorafenib Tablet for Oral Suspension
The primary objective of the study is to Investigate the relative bioavailability of sorafenib as 400 mg (4 x 100 mg) tablet for oral suspension formulation in comparison to 400 mg (2 x 200 mg) marketed tablet formulation.
- Trial name
- NCT02538393
- Testing
- Sorafenib (BAY43-9006) Film-coated tablet, Sorafenib (BAY43-9006) Oral suspension
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy
Study of the Effect of Food Intake on the Bioavailability of XC221 100 mg Tablets
Primary objective of the study: evaluation of the effect of food intake on the bioavailability of XC221 100 mg tablets after a single oral administration in fed or fasted condition.
- Trial name
- NCT05295121
- Testing
- XC221 100 mg tablets
- Where
- Russia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Valenta Pharm JSC
Food Labeling, Choice Behavior
Impact of Nutrition Labels on Consumer Purchasing Intentions
The purpose of this interventional study is to compare the impact of four different Front-Of-Pack (FOP) nutrition labels on purchasing intentions.
- Trial name
- NCT02385838
- Testing
- 5-CNL, MTL, GDA
- Where
- France
- Volunteers
- 11,981 people, healthy volunteers welcome
- Sponsor
- University of Paris 13
Healthy
Safety and Tolerability, Pharmacokinetic and Pharmacodynamic Study With Inzomelid
This is a first in human (FIH), single-centre, double blind, randomised, cross-over, SAD followed by a MAD study of Inzomelid. The study is designed to evaluate the safety, tolerability, PK, PD, and food effect of Inzomelid in…
- Trial name
- NCT04015076
- Testing
- Inzomelid
- Where
- Australia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Inflazome UK Ltd
Healthy Volunteer
Food Effect Study in Healthy Volunteers
A phase 1 open-label, randomized, crossover food effect and formulation assessment for icovamenib capsule in healthy volunteers.
- Trial name
- NCT07254286
- Testing
- Icovamenib, Icovamenib HPMC
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Biomea Fusion Inc.
Healthy
A Study of Bedaquiline 100 Milligram (mg) Tablets Administered as Different Test Formulations Compared to the Commercial Tablet Formulation (F001) in Healthy Adult Participants
The purpose of this study is to assess the rate and extent of absorption of bedaquiline following administration of a single oral dose of 100 milligram (mg) equivalent (1*100 mg) given as different test tablet formulations…
- Trial name
- NCT04087759
- Testing
- Bedaquiline (Test formulation), Bedaquiline (Reference formulation)
- Where
- Belgium
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Food Effect in Healthy Participants
A Food Effect Study of JAB-21822 in Healthy Subjects
The primary objective of this study is to determine the effect of food in healthy participants on the bioavailability of JAB-21822 following single dose administration with and without a meal
- Trial name
- NCT05875493
- Testing
- JAB-21822
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Allist Pharmaceuticals, Inc.
Healthy Volunteers
A Food-Effect Study of AND017 in Healthy Participants
The purpose of this phase I study is to evaluate the food effect on the PKs of AND017 following oral single-dose administration in healthy non-elderly Chinese subjects.
- Trial name
- NCT04712500
- Testing
- AND017
- Where
- China
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Kind Pharmaceuticals LLC
Health Behavior
The Effectiveness of PACE Label on Reducing Food Consumption and Increasing Physical Activity Levels
Background: More people are at the risk of chronic disease as the prevalence of obesity increases. It is therefore essential to find ways of helping consumers to make a lower calorie food choice.
- Trial name
- NCT05143515
- Testing
- PACE label
- Where
- United Kingdom
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Loughborough University