Clinical trials: Food Systems
Diabetes Mellitus
A Study to Evaluate the Effect of Food on the Pharmacokinetics of Sotagliflozin and to Explore the Relative Bioavailability in Healthy Subjects
Primary Objective: To evaluate the effect of food on the single-dose pharmacokinetics of sotagliflozin relative to a fasted state in healthy adult male and female subjects.
- Trial name
- NCT03174548
- Testing
- Sotagliflozin (SAR439954)
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Sanofi
Low Weight Eating Disorders, Anorexia Nervosa
Reward Systems and Food Avoidance in Eating Disorders
The researchers plan to explore brain networks involved in emotion processing and learning using a brain scan and test meals. One core feature of Anorexia Nervosa (AN) is eating a small number of high-calorie or high-fat foods.
- Trial name
- NCT02795455
- Testing
- Interoceptive Exposure (IE), Family Based Therapy-Weight Gain Control (FBT-WG), meal replacement shake
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Vitamin B-12 Deficiency, Achlorhydria
Cobalamin Absorption From Fortified Food
To determine B12 bioavailability from 14C-B12 fortified bread in healthy subjects and in subjects with proton pump inhibitor induced achlorhydria.
- Trial name
- FL-72 (NCT01399164)
- Testing
- 14C-B12 fortified bread
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Healthy Adults, Copeptin
Copeptin Changes After Food Intake
The purpose of this study is to determine whether copeptin levels are affected by food intake.
- Trial name
- CoMeal (NCT01772914)
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Healthy Volunteers
Pharmacokinetics of a Fixed Dose Combination of Canagliflozin/Metformin Coadministered With Food
The purpose of this study is to assess the effect of coadministration of a high-fat meal on the oral bioavailability of a fixed dose combination of Canagliflozin/extended release Metformin (CANA/MET XR) tablet, containing 150 mg…
- Trial name
- NCT02039258
- Testing
- CANA/MET XR FDC
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Infection, Human Immunodeficiency Virus
Food Effect Study With BMS-955176
The purpose of this study is to assess the impact of a light meal, a standard meal, and a high fat meal on the PK of BMS-955176 MC tablet at a dose of 180 mg, relative to fasted conditions.
- Trial name
- NCT02273947
- Testing
- BMS-955176
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Hepatitis C
A Open-label Study to Evaluate the Relative Bioavailability of Samatasvir (IDX184) and Food Effect in Healthy Male Participants (MK-2355-006)
The purpose of this study is to: Assess the relative bioavailability of 2 oral formulations of samatasvir (capsule and tablet prototype test formulation) Compare the amount of study drug that is in the blood after taking either…
- Trial name
- NCT01335607
- Testing
- Samatasvir tablet, Samatasvir capsule
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes, Healthy
Soluble Fibre Enriched CHO Food Study
The proposed study will examine the effects of incorporating a soluble fibre blend into commonly consumed refined carbohydrate foods on sensory parameters and postprandial blood glucose.
- Trial name
- NCT01898026
- Testing
- Bread, Mashed Potatoes, Muffins
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
IgA Nephropathy, Paroxysmal Nocturnal Hemoglobinuria
A Clinical Study to Evaluate the Effect of Food on the Pharmacokinetic Profiles of HRS-5965 Capsules in Healthy Subjects
The study is being conducted to evaluate the effect of food on pharmacokinetics of HRS-5965 capsules after oral administration.
- Trial name
- NCT07035665
- Testing
- HRS-5965 Capsules
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Chengdu Suncadia Medicine Co., Ltd.
Parkinson's Disease
Safety, Tolerability, Pharmacokinetics (Including Food Interaction), and Pharmacodynamics of BIA 3-202
The purpose of this study is to investigate the safety and tolerability of single oral rising doses of BIA 3-202 up to 800 mg (proposed doses 10 mg, 30 mg, 50 mg, 100 mg, 200 mg, 400 mg and 800 mg) in groups of 9 healthy male…
- Trial name
- NCT02763787
- Testing
- BIA 3-202
- Where
- United Kingdom
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Bial - Portela C S.A.
Eosinophilic Gastrointestinal Disease Eosinophilic Inflammatory Disease, Food Allergy
Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders
The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration, and function and to investigate and further characterize the pathophysiology of, clinical manifestations of, and spectrum…
- Trial name
- NCT00267501
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Obesity, Overweight
Food Rheology and Feeding in Lean and Obese Humans
The 2010 National Health Objectives call for a reduction in the prevalence of obesity. The marked recent increase in overweight and obesity prevalence implicates behavioral factors in the etiology of the epidemic.
- Conditions
- Obesity, Overweight, Diabetes
- Trial name
- NCT00260130
- Testing
- food in fluid form, food in solid form
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Purdue University
Food Allergy
Allergenicity Assessment of Green Marine Macroalga Ulva sp.
To determine the allergenic potential in humans, we will conduct a three-stage clinical trial. In the first group, 20 healthy volunteers will be involved.
- Trial name
- NCT06452381
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Twin Pregnancy, Antepartum Condition or Complication, Gestational Diabetes
Diet in Twin Pregnancy: the Wellness of Mother and Babies.
The aim of this study is to evaluate how variations in maternal nutrition may affect twin pregnancy and in particular: incidence of maternal obstetric complications: gestational diabetes gestational hypertension or preeclampsia…
- Conditions
- Twin Pregnancy, Antepartum Condition or Complication, Gestational Diabetes, Gestational Hypertension, Intrahepatic Cholestasis of Pregnancy
- Trial name
- FIT (NCT05773677)
- Testing
- Specific Diet
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Chronic Hepatitis B
A Study of Orally Administered JNJ-440 to Evaluate the Safety, Tolerability, and Pharmacokinetics After Single Ascending Doses Including Food Effect Evaluation; After Multi-Day Dosing in Healthy Participants; and After Multiple (Ascending) Doses in Participants With Chronic Hepatitis B
The purpose of this study is to evaluate the safety and tolerability of JNJ-440 in healthy and Chronic Hepatitis B (CHB) participants after single and multiple doses; and to evaluate the pharmacokinetic (PK) of JNJ-440 in healthy…
- Trial name
- NCT03439488
- Testing
- JNJ-440
- Where
- 7 sites in Moldova, New Zealand and 3 more
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Alios Biopharma Inc.
Cow Milk Allergy
Growth and Plasma Amino Acids in Infants With CMPA and Treated With a Newly Innovated Amino Acid Formula
The purpose of this study is to determine growth and protein status of infants with cow's milk protein allergy and treated with a newly innovated amino acid formula compared to those with a commercial amino acid formula.
- Trial name
- CMPA (NCT01637688)
- Testing
- Comparison of treatment with different amino acid formulas
- Where
- Thailand
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Diabetes Mellitus, Type II
Investigate the Effect of Food on the Pharmacokinetic Characteristics of CKD-395 in Healthy Male Volunteers
This study is A randomized, open-label, single dose, 2-way crossover study to investigate the effect of food on the pharmacokinetic characteristics of CKD-395 in healthy male volunteers.
- Trial name
- NCT02648854
- Testing
- CKD-395 0.5(Lobeglitazone)/1000(Metformin)mg 1T
- Where
- South Korea
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Migraine
Study on the Pharmacokinetics (PK) of DFN-15 vs Comparator and Food-effect on DFN-15 PK in Healthy Adult Subjects
An Open-Label, Three-Way Randomized, Single Dose Crossover Study Comparing Bioavailability of DFN-15 under fasting conditions versus Comparator under fed conditions and to determine food-effect of DFN-15 in Healthy Adult Subjects
- Trial name
- NCT03282838
- Testing
- DFN-15 (fasted), DFN-15 (fed), Comparator Celebrex® (fed)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Chronic Spontaneous Urticaria
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Food Effect of Single and Multiple Doses of HRS-3095 Oral Administration in Healthy Subjects, as Well as the Effect of HRS-3095 on CYP3A4 Metabolic Enzymes
The study is being conducted to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple doses of HRS-3095 oral administration in healthy subjects.
- Trial name
- NCT07230418
- Testing
- HRS-3095 Tablet
- Where
- China
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Chengdu Suncadia Medicine Co., Ltd.