Clinical trials: Foot/Ankle
Arthritis Foot, Trauma Injury
Artoss Foot and Ankle Surgery Registry
This prospective registry was designed as an observational study to ascertain how commercially available NanoBone products are being used by surgeons performing foot and ankle surgery which involves bone grafting, as well as…
- Conditions
- Arthritis Foot, Trauma Injury, Deformity; Bone
- Trial name
- ARK (NCT04503759)
- Testing
- NanoBone Bone Graft Substitute
- Where
- 8 sites in United States
- Volunteers
- 200 people
- Sponsor
- Artoss Inc.
Injuries, Ankle, Sprain of Foot
Multisegmented Foot Motion in Patients With Lateral Ankle Sprains and Chronic Ankle Instability
Lateral ankle sprains (LAS) and chronic ankle instability (CAI) are common musculoskeletal injuries that are a result of inversion injury during sport.
- Trial name
- NCT02697461
- Testing
- Intrinsic Foot Strengthening, Joint Mobilization
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Peripheral Artery Disease (PAD), Diabetes Mellitus Type 2
Effect of Diabetic Foot Exercises on Peripheral Vascular Status in Type 2 Diabetes Mellitus Patients
This randomized controlled trial aims to evaluate the effectiveness of diabetic foot exercises on peripheral vascular status among patients with type 2 diabetes mellitus.
- Conditions
- Peripheral Artery Disease (PAD), Diabetes Mellitus Type 2, Diabetic Foot Circulation Impairment
- Trial name
- NCT07262203
- Testing
- Diabetic Foot Exercise Program
- Where
- Indonesia
- Volunteers
- 44 people
- Sponsor
- Universitas Muhammadiyah Surakarta
Pronation; Ankle
Kinematic Parameters of Running in Individuals With Pronated Foot
The aim of the study is to examine the kinematic parameters of individuals with pronated foot compared with individuals with normal foot
- Trial name
- NCT03557866
- Testing
- running
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Geriatric, Foot Ankle Injuries
Foot And Ankle Proprıoceptıve Exercıse Program
This study will be conducted to evaluate whether the foot and ankle proprioceptive exercise program contributes to foot posture, physical performance and fall incidence in geriatric individuals.
- Conditions
- Geriatric, Foot Ankle Injuries, Exercise, Fall in Nursing Home
- Trial name
- NCT07522827
- Testing
- home exercise, Foot and ankle proprioceptive exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ankara University
Knee Arthroplasty
Continuous Monitoring of Physiology and Self-reported Pain Score Amongst Post-surgical Knee Patients
The aim of this observational study is to assess whether patient reported pain levels correlate with a Pain Index derived from deviations in multivariate physiology biomarkers captured in real-world setting.
- Trial name
- ObservePAIN (NCT03789630)
- Testing
- Continuous physiology monitoring in ambulatory setting pre and post surgery
- Where
- Singapore
- Volunteers
- 55 people
- Sponsor
- Biofourmis Singapore Pte Ltd.
Foot Injuries and Disorders, Ankle Injuries and Disorders
Dexamethasone vs. Dexmedetomidine for Popliteal Nerve Block in Pain Management After Pediatric Ankle and Foot Surgery
Effect of perineurial dexamethasone and dexmedetomidine on popliteal nerve block duration for pediatric, ankle or foot surgery
- Trial name
- NCT06233565
- Testing
- 0.9%sodium chloride, Dexamethasone, Dexmedetomidine
- Where
- 2 sites in Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Ankle Sprain
Validation of the Foot and Ankle Ability Measure Tool in Finnish
The purpose of this study is to validate the Foot and Ankle Ability Measure in Finnish.
- Trial name
- FAAM-Fi (NCT02330198)
- Where
- Finland
- Volunteers
- 84 people
- Sponsor
- Turku University Hospital
CHRONIC POST-TRAUMATIC NEUROPATHIC PAIN IN ANKLE AND FOOT
Pilot RCT of Efficacy of Perineural Local Anesthetics and Steroids for Chronic Post-traumatic Ankle and Foot Pain
Injections of local anesthetics (freezing) and steroids are often performed around injured nerves in individuals with nerve injury-related pain.
- Trial name
- PREPLANS (NCT02680548)
- Testing
- 0.9% saline, 0.25% bupivacaine hydrochloride injectable suspension USP, 4mg/cc methylprednisolone acetate injectable suspension USP
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University Health Network, Toronto
X-linked Hypophosphatemia
Foot Disorders in X-linked Hypophosphatemia
This study aimed to characterize foot pathologies using X-rays and clinical examination and assess related outcome scores in adolescents and adults with X-linked Hypophophatemia
- Trial name
- NCT06067932
- Testing
- Foot X rays, Clinical examination + scores
- Where
- Austria
- Volunteers
- 28 people
- Sponsor
- Orthopedic Hospital Vienna Speising
Osteoarthritis (OA), Osteoarthritis (OA) of the Knee
Platelet Rich Plasma for Musculoskeletal Conditions
The primary purpose of this study is to follow patients with various musculoskeletal (MSK) conditions over a one-year follow-up period after receiving a platelet rich plasma (PRP) injection, assessing changes in their pain…
- Conditions
- Osteoarthritis (OA), Osteoarthritis (OA) of the Knee, Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Shoulder
- Trial name
- PRP for MSK (NCT07231471)
- Testing
- Platelet Rich Plasma Injection, Platelet Rich Plasma Preparation
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Utah
Rotator Cuff Tears, Shoulder Injuries
Randomized Study of an Analgesic Device Enabling Local Anesthetic Delivery and Neuromodulation After Shoulder/Foot Surgery
Postoperative pain remains undertreated with inadequate analgesic options. Opioids have well-known limitations for both individuals and society; single-injection and continuous peripheral nerve blocks provide intense analgesia…
- Conditions
- Rotator Cuff Tears, Shoulder Injuries, Hallux Valgus, Ankle Arthropathy
- Trial name
- NCT07052721
- Testing
- Experimental Treatment
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of California, San Diego
Ankle Trauma, Education
Mnemonic for the Ottawa Ankle Rule
The purpose of this study is to evaluate wether the use of a mnemonic strategy could improve the recall of the Ottawa Ankle and foot Rules' guidelines among medical students and residents
- Trial name
- NCT00652353
- Testing
- 44-55-66-PM, control
- Where
- Canada
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Foot Ankle Injuries, Anticoagulants and Bleeding Disorders
A Prospective Study in Chinese Patients With Lower Extremity Ankle Fracture of Oral Anticoagulants to Prevent Venous Thromboembolism (VTE)
Deep vein Thrombosis (Deep Venous Thrombosis, DVT) and Pulmonary Embolism, Pulmonary Embolism, PE) both collectively known as Venous thromboembolism (VTE) (Venous Thrombus Embolism, VTE), is a common clinical disease, and…
- Conditions
- Foot Ankle Injuries, Anticoagulants and Bleeding Disorders, Venous Thromboembolism
- Trial name
- NCT04128254
- Testing
- Apixaban Oral Tablet
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Injuries, Injury Arm
Virtual Reality for Pain in Acute Orthopedic Injuries
The goal of this study is to pilot test a skills-based virtual reality (VR) for acute orthopedic injury. It will measure the feasibility, signals of improvement, exploratory pain mechanisms, and user experience of an established…
- Conditions
- Injuries, Injury Arm, Injury;Sports, Injury, Knee
- Trial name
- NCT05552430
- Testing
- RelieveVRx
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts General Hospital
Hallux Valgus
Medial Forefoot Block for Analgesia After Foot Surgery
Forefoot surgery includes bunion surgery and similar reconstructive bone cutting surgery and is very painful. Local anaesthetic nerve blocks are used to provide pain relief after this work.
- Trial name
- NCT01445249
- Testing
- Landmark guided ankle block., PNS guided block.
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Diabetes, Peripheral Arterial Occlusive Disease
Evaluate the Correlation of NIRS, ABI, Exercise, baPWV and Albuminuria With Peripheral Artery Occlusion Disease (PAD) and Other Atherosclerosis Outcomes
By utilizing Near infrared spectroscopy (NIRS), the local blood flow, tissue oxygenation (StO2), and recovery time of ischemic leg; can be determined.
- Trial name
- NCT03378024
- Testing
- oscillometric (Omron Colin co)
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Equinus Contracture
The Effect of Botulinum Toxin A Injections on Ankle Dorsiflexion Following Internal Fixation of Tibial Pilon Fractures
The purpose of this study is to determine if botulinum toxin type A (Botox) injections, at the time of surgery for pilon fractures, will improve ankle range-of-motion and functionality.
- Trial name
- Botox (NCT02051933)
- Testing
- Botulinum toxin type A, sodium chloride
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Plantar Fascitis
Comparative Effects of Gun Massager and Transverse Friction Massage in Patients With Plantar Fasciitis
to compare the effects of massage gun and transverse friction massage on management of pain and disability in patients with plantar fasciitis.
- Trial name
- NCT05347264
- Testing
- gun massager, transverse friction massage
- Where
- Pakistan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Pain, Postoperative, Pain, Acute Postoperative
Exparel Use in Peripheral Nerve Blocks and Local Infiltration for Foot and Ankle Surgery
Liposomal Bupivacaine (Exparel) has been recently studied as the active agent utilized in various nerve block. Due to its liposomal form allowing for extended delivery, Exparel has been used in various peri-operative nerve blocks…
- Conditions
- Pain, Postoperative, Pain, Acute Postoperative, Ankle Fractures, Ankle Injuries and Disorders
- Trial name
- NCT05494645
- Testing
- Exparel, Peripheral Nerve Block
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- St. Luke's Hospital, Pennsylvania