Clinical trials: Foot/Ankle
Diabetic Foot
Cutoff Value of Ankle Brachial Pressure Index for Vacuum Assisted Closure Application in Diabetic Foot Ulcers
Abstract Objective To verify cutoff value of ankle brachial pressure index at which diabetic foot ulcers get benefit from vacuum assisted closure application and to assess impact of its application on ankle brachial pressure…
- Trial name
- NCT06000371
- Testing
- Vacuum assisted Closure application
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Mansoura University
Vitamin D Deficiency
Does Supplementing Vitamin D Deficiency Affect Fusion Healing Rates in Elective Foot and Ankle Surgery?
To assess if vitamin D status in the elective foot and ankle fusion population affects fusion healing categorically (fused vs. un-fused).
- Trial name
- NCT04450199
- Testing
- Vitamin D2
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Foot Drop, Peripheral Nervous System Diseases
Walking Ankle Robot for Foot Drop in Aging and Disabled Populations: A Demonstration Project
The purpose of this research study is to test the utility of an ankle robot, when used during treadmill walking, in people with ankle weakness and foot drop from a peripheral nervous system injury due to neuromuscular or…
- Conditions
- Foot Drop, Peripheral Nervous System Diseases, Gait Disorders, Neurologic, Mobility Limitation
- Trial name
- NCT03556709
- Testing
- Treadmill Ankle Robot Training
- Volunteers
- 100 people
- Sponsor
- Baltimore VA Medical Center
Foot Fusion
Augment® Bone Graft (Formerly GEM OS™1 Bone Graft) Compared to Autologous Bone Graft in Foot and Ankle Fusions
STUDY OBJECTIVES: Demonstrate equivalent clinical and radiologic outcomes to the "gold standard" (ABG) in a representative clinical model (hindfoot and ankle fusions) STUDY HYPOTHESIS: Augment® Bone Graft is an equivalent bone…
- Trial name
- NCT00583375
- Testing
- Augment® Bone Graft, Standard of Care
- Where
- 37 sites in United States, Canada
- Volunteers
- 414 people
- Sponsor
- BioMimetic Therapeutics
Lower-Limb Amputation
Evaluation of a New Articulated Prosthetic Foot: Comfort, Safety and Biomechanics in Individuals With a Lower-Limb Amputation
This clinical investigation aims to evaluate a new articulated prosthetic foot during daily-life activities.
- Trial name
- MAP-CSB (NCT07530601)
- Testing
- New Articulated Prosthetic Foot, Current Prosthetic foot
- Where
- 2 sites in Belgium
- Volunteers
- 120 people
- Sponsor
- Vrije Universiteit Brussel
Peripheral Artery Disease
Improving Mobility in Peripheral Artery Disease Using an Ankle Foot Orthosis
This study will determine whether an ankle foot orthosis (AFO) improves walking performance in participants with PAD from its first use.
- Trial name
- NCT02902211
- Testing
- Ankle foot orthosis, Control/standard of care
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Other Instability, Ankle and Foot
The Effect of Strain-counterstrain on Ankle Instability
This study seeks to determine the effectiveness of Strain Counterstrain in the treatment of chronic ankle instability.
- Trial name
- NCT02025569
- Testing
- Strain Counterstrain
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Long Island University
Ankle Arthrodesis, Hindfoot Arthrodesis
Foot and Ankle Clinic Application for Liposomal Related Anesthetic
The purpose of this study is to review the use of surgeon applied liposomal release anesthetic (Exparel) for post operative analgesia.
- Conditions
- Ankle Arthrodesis, Hindfoot Arthrodesis, Tibitalocalceal Arthrodesis
- Trial name
- NCT02586077
- Testing
- Exparel
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Cerebral Palsy
Compliance in Children With Cerebral Palsy Supplied With AFOs
Children with cerebral palsy are frequently supplied with Ankle Foot Orthoses (AFOs) to aid their walking. There are huge benefits to patients in staying physically active into adulthood but this becomes more challenging as…
- Trial name
- NCT04081675
- Testing
- Ankle Foot Orthosis (AFO)
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Ankle Disorders Injuries
Urdu Translation And Cross-Cultural Validation of the Foot And Ankle Disability Index
The goal of this Cross-cultural validation study is to Urdu translate and cross-cultural validation of Foot and Ankle Disability Index for the Patients with Chronic Ankle Instability.
- Trial name
- NCT05732636
- Testing
- Validation study
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Sehat Medical Complex
Cerebral Palsy
Muscle Activity With the Use of Ankle Foot Orthoses in Cerebral Palsy
The purpose of this study is to investigate the change in muscle activity during gait with the use of ankle foot orthoses in children diagnosed with hemiplegic cerebral palsy.
- Trial name
- NCT00462085
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital Basel
Post-surgical Pain, Total Knee Arthroplasty
Effects of Catheter Location on Postoperative Analgesia for Continuous Adductor Canal and Popliteal-Sciatic Nerve Blocks
Currently, continuous adductor canal and popliteal-sciatic nerve blocks are used commonly for lower extremity post-operative pain control, specifically for total knee arthroplasty and foot/ankle surgery, respectively.
- Conditions
- Post-surgical Pain, Total Knee Arthroplasty, Foot/Ankle Surgery, Catheterization for Postop Analgesia
- Trial name
- NCT02523235
- Testing
- ropivacaine 0.2%
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- University of California, San Diego
Hypertension, Ankle Edema
Assessment of Aliskiren/Amlodipine and Amlodipine on Ankle Foot Volume (AFV) in Patients With Hypertension
The purpose of the present study was to evaluate the addition of aliskiren, to amlodipine can attenuate ankle edema formation in hypertensive patients.
- Trial name
- NCT01080768
- Testing
- Aliskiren/amlodipine, Amlodipine
- Where
- 9 sites in Netherlands
- Volunteers
- 31 people
- Sponsor
- Novartis Pharmaceuticals
Ankle Pathology, Foot Pathology
PROMIS and Patient Satisfaction
The primary aim for this study is to determine if patient satisfaction and experience is improved with the active discussion/inclusion of PROMIS scores during new foot and ankle clinic patient visits.
- Trial name
- NCT04654910
- Testing
- PROMIS Score Explanation
- Where
- United States
- Volunteers
- 275 people
- Sponsor
- University of Rochester
Rheumatoid Arthritis
Can Musculoskeletal Ultrasound Predict Fall Risk in Rheumatoid Arthritis Patients?
Rheumatoid patients have higher fall risk than normal population. Several fall risk factors were studied. No previous study investigated the role of musculoskeletal ultrasound as a predictor of fall risk in rheumatoid arthritis.
- Trial name
- NCT04464096
- Testing
- non
- Where
- Egypt
- Volunteers
- 101 people
- Sponsor
- Assiut University
Multiple Sclerosis
The Effects of Ankle Foot Orthoses (AFOs) on Mobility in Persons With Multiple Sclerosis (MS)
The purpose of this study is to investigate the impact of ankle foot orthoses (AFOs) on the spatial and temporal gait parameters, electromyography (EMG), walking endurance, and quality of life in select individuals living with…
- Trial name
- NCT01947582
- Testing
- Ankle foot orthosis
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Texas Southwestern Medical Center
Foot Drop
Validation of an Ankle Foot Orthosis With Anterior Support for Foot Drop
The objective of this research is to compare the new ankle foot orthosis (AFO) with prior support developed by Turbomed, with the AFO with posterior support from Turbomed as well as two competing AFOs currently on the market.
- Trial name
- NCT05163782
- Testing
- New ankle foot orthosis with anterior support, Ankle foot orthosis with anterior support, Ankle foot orthosis from competitor 1
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- TOPMED
Spinal Cord Injuries, Spastic Gait
Neuromodulation of Ankle Muscles in Persons With SCI
The ability to voluntarily move the ankles is important for walking. After spinal cord injury (SCI), this ability is impaired because of changes in the communication between the brain, spinal cord, and body.
- Conditions
- Spinal Cord Injuries, Spastic Gait, Foot Drop
- Trial name
- NCT04238013
- Testing
- Whole Body Vibration (WBV), Electrical Stimulation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Shepherd Center, Atlanta GA
Pain in Leg, Unspecified, Knee Sprain
Efficacy of Instrumental Chiropractic Treatment Using Activator Methods for Pain and Dysfunction in Juvenile Athletes
The goal of the study is to prove efficacy of instrumental chiropractic treatment for leg pain in juvenile athletes. A randomized placebo controlled clinical trial including juvenile athletes with functional impairment and pain…
- Trial name
- NCT01449994
- Testing
- Activator IV (Activator Methods Int. Phoenix, Arizona)
- Where
- Austria
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Ankle Injuries, Foot Injuries and Disorders
Weight Change With Controlled Ankle Movement (CAM) Boot Use
The purpose of the study is to determine if patients wearing a CAM boot have a change in weight compared to patients who wear a CAM boot and are provided nutritional guidelines and perform upper body exercises.
- Conditions
- Ankle Injuries, Foot Injuries and Disorders, Body Weight Changes
- Trial name
- CAM (NCT05692401)
- Testing
- Nutrition and Exercise Instruction
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Nell Blake, DPM