Clinical trials: Foot & Ankle
Wound Heal, Diabetic Foot Ulcer
Effect of New High Ankle Block on Wound Healing After the Operation of Debridement of Diabetes Foot
The goal of this clinical trial is to compare high ankle block and general anesthesia on wound recovery and ankle blood flow perfusion after diabetes foot surgery in diabetics.
- Trial name
- NCT06395961
- Testing
- high ankle block, general anesthesia
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Xuzhou Central Hospital
Medication Disposal, Behavior
Excess Opioid Disposal Following Orthopedic Foot and Ankle Surgery
This study aims to survey the drug disposal methods of orthopedic foot and ankle patients with excess pain medication following and operation.
- Trial name
- NCT03285061
- Testing
- Deterra Drug Deactivation System
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Surgery, Edema
Foot and Ankle Post-operative Oedema Management Using Geko™
The multicentre randomised geko™ Foot and Ankle Trial will prospectively and systematically collect clinical data on patients randomised, on a 1:1 basis, to either standard care or standard care plus geko™ therapy to assess…
- Trial name
- NCT04927234
- Testing
- geko™ therapy
- Where
- 5 sites in United States, Spain and 1 more
- Volunteers
- 123 people
- Sponsor
- Firstkind Ltd
Hypertension, Ankle Edema
Assessment of Aliskiren/Amlodipine and Amlodipine on Ankle Foot Volume (AFV) in Patients With Hypertension
The purpose of the present study was to evaluate the addition of aliskiren, to amlodipine can attenuate ankle edema formation in hypertensive patients.
- Trial name
- NCT01080768
- Testing
- Aliskiren/amlodipine, Amlodipine
- Where
- 9 sites in Netherlands
- Volunteers
- 31 people
- Sponsor
- Novartis Pharmaceuticals
Multiple Sclerosis
Effectiveness of Ankle Foot Orthoses on Gait in Multiple Sclerosis
The purpose of this study is to investigate the impact of a specifically designed ankle foot orthosis (AFO, hinged, with tamarack joint and adjustable check strap) on the spatial and temporal gait parameters, electromyography…
- Trial name
- NCT01796860
- Testing
- AFO
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Texas Southwestern Medical Center
Transtibial Amputation - Unilateral
Comparison of Various Prosthetic Foot-Ankle Mechanisms
In summary, subjects will be asked to wear a number of sensors and use different ankle-foot prostheses in place of their customary prosthesis.
- Trial name
- NCT05964855
- Testing
- MIT Variable Stiffness Prosthesis v1, MIT Variable Equilibrium Angle Prosthesis v1, MIT Sliding Beam Passive Prosthesis
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts Institute of Technology
Ankle Fractures, Trauma Injury
Effect of Toradol on Post-operative Foot and Ankle Healing
The use of Toradol for pain control in surgical orthopedic cases is currently a topic of interest within the field. The proposed study is a prospective randomized study evaluating postoperative pain, opioid requirement…
- Trial name
- NCT03727048
- Testing
- Ketorolac, No ketorolac
- Volunteers
- 128 people
- Sponsor
- Rothman Institute Orthopaedics
Open Reduction Internal Fixation(ORIF) of Lateral Malleolus
Sciatic Nerve Block for Ankle/Foot Surgeries. A Comparison Between a Premixed Solution of Lidocaine Plus Bupivacaine and Consecutive Infiltration of Lidocaine and Bupivacaine
Regional anaesthesia has become the cornerstone of multimodal analgesia. With the advent of ultrasound guided nerve blocks regional anaesthesia has achieved both greater efficacy and a better safety profile as the injection of…
- Trial name
- NCT01756443
- Testing
- 2% lidocaine/adrenaline and 0.5% bupivacaine
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- Cork University Hospital
Adult ALL, Healthy
Iterative Design of Custom Dynamic Orthoses
The proposed study evaluates the effect of carbon fiber brace design on forces across the ankle joint. It is expected that carbon fiber braces can be designed to reduce forces in the ankle.
- Trial name
- PRMRP-Norms (NCT04800510)
- Testing
- Carbon Fiber Custom Dynamic Orthosis (CDO)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Iowa
Flatfoot
Foot Positions Affect Knee and Ankle Proprioception, Balance, Vertical Jump, and Muscle Activity in Individuals With Flexible and Rigid Flatfoot and Chronic Ankle Instability
To investigate the effect of various foot positions affect knee and ankle proprioception, balance, vertical jump, and muscle activity in individuals with flexible and rigid flatfoot and chronic ankle instability
- Trial name
- NCT05899855
- Testing
- No intervention
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Ankle Injuries, Ankle Sprains
Ankle Instability Using Foot Intensive Rehabilitation
The overall objective of this study is to examine the effects of a 6-week foot-intensive rehabilitation (FIRE) program on lateral ankle sprain (LAS) re-injury rates, CAI symptoms, sensorimotor function, and self-reported…
- Trial name
- FIRE (NCT04493645)
- Testing
- Standard of Care Rehabilitation (SOC), Foot Intensive Rehabilitation (FIRE)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Matthew Hoch
Ankle Sprains, Chronic Ankle Instability
Effects of the Elastic Taping on the Chronic Ankle Instability
This study will analyze the effects of an elastic taping application protocol in individuals with chronic ankle instability. One group will perform a protocol with increased tape tension for five weeks while the other group will…
- Conditions
- Ankle Sprains, Chronic Ankle Instability, Athletes Foot
- Trial name
- NCT04568577
- Testing
- Tape with tension, Tape without tension
- Where
- Brazil
- Volunteers
- 27 people
- Sponsor
- Universidade Norte do Paraná
Ankle Surgery, Foot Surgery
MIDCAB (Mid-Calf Block) for Foot Surgery
MIDCAB is defined as a group of ultrasound guided distal nerve blocks at the level of the individual branches. It is similar to an Ultrasound Guided (USG) Ankle block but the probe is placed higher on the calf covering all and…
- Trial name
- MIDCAB (NCT05368012)
- Testing
- MIDCAB
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hospital for Special Surgery, New York
Foot and Ankle Edema
Foot and Ankle Edema Post-Cesarean Delivery
Some women develop swollen feet and ankles after a cesarean delivery. These women will often complain that their shoes are too tight and their feet may become numb or they may have some tingling in their feet.
- Trial name
- NCT00488956
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- University of British Columbia
Foot Injuries and Disorders
SCANREP: Reliability of 3D Lower Limb Scanning
3D limb scanning systems have recently been implemented for the clinical fitting of prosthetic and orthotic devices due to substantial decreases in costs.
- Trial name
- NCT04032041
- Testing
- Structure Sensor, Caliper
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Stroke
Identifying the Optimal Dynamic Ankle-Foot Orthosis Bending Stiffness for Individuals Post-Stroke
Ankle braces are commonly prescribed to individuals who have suffered a stroke to help their ankle joints work properly, which allows these individuals to walk better.
- Trial name
- NCT06304519
- Testing
- Dynamic ankle-foot orthosis
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Delaware
Cerebrovascular Accident, Post-polio Syndrome
Nomad P-KAFO Study
The goal of this clinical trial is to evaluate the impact of using the Nomad powered KAFO in people who have had a musculoskeletal or neurological injury that has affected their ability to walk.
- Conditions
- Cerebrovascular Accident, Post-polio Syndrome, Spinal Cord Injuries, Multiple Sclerosis
- Trial name
- NCT05644522
- Testing
- Indego Nomad® Powered Knee-Ankle-Foot Orthosis (P-KAFO) (Parker Hannifin Corp., Cleveland, OH)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Shirley Ryan AbilityLab
Ankle Fractures, Foot Fracture
Waterproof Casting Versus Standard Casting for Short Leg Walking Casts
The purpose of the study is to determine whether the use of waterproof padding in short leg walking casts will lead to an increase in cast-related complications, as compared to the standard non-waterproof casting in children.
- Conditions
- Ankle Fractures, Foot Fracture, Ankle Sprains, Foot Sprain
- Trial name
- NCT04961957
- Testing
- Waterproof padding, Non-waterproof padding
- Where
- United States
- Sponsor
- West Virginia University
Lower Limb Surgery
Retrospective Foot and Ankle Data Collection
A retrospective post-market data collection study of the following implant devices : DARCO™ Headed Cannulated Screw ORTHOLOC™ 3Di Recon-Midfoot/Flatfoot System ORTHOLOCTM 3Di 2 Foot Reconstruction System: CROSSCHECK™ Module
- Trial name
- NCT05234801
- Testing
- DARCO™ Headed Cannulated Screw, ORTHOLOC™ 3Di Recon-Midfoot/Flatfoot System, ORTHOLOCTM 3Di 2 Foot Reconstruction System: CROSSCHECK™ Module
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Knee Arthroplasty
Continuous Monitoring of Physiology and Self-reported Pain Score Amongst Post-surgical Knee Patients
The aim of this observational study is to assess whether patient reported pain levels correlate with a Pain Index derived from deviations in multivariate physiology biomarkers captured in real-world setting.
- Trial name
- ObservePAIN (NCT03789630)
- Testing
- Continuous physiology monitoring in ambulatory setting pre and post surgery
- Where
- Singapore
- Volunteers
- 55 people
- Sponsor
- Biofourmis Singapore Pte Ltd.