Clinical trials: Foot Injuries
Chronic Wounds, Burns
THERAVEX Tissue Care Spray Plus for the Management of Cutaneous Wounds, Burns, and Chronic Ulcers
Pilot observational clinical evaluation assessing the safety and potential effectiveness of THERAVEX Tissue Care Spray Plus as an adjunctive topical therapy for the management of cutaneous wounds, burns, traumatic lesions…
- Conditions
- Chronic Wounds, Burns, Pressure Ulcer, Traumatic Wounds
- Trial name
- NCT07617961
- Testing
- THERAVEX TISSUE CARE SPRAY PLUS
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Biointelligent Technology Systems SL
Osteoarthritis (OA), Osteoarthritis (OA) of the Knee
Platelet Rich Plasma for Musculoskeletal Conditions
The primary purpose of this study is to follow patients with various musculoskeletal (MSK) conditions over a one-year follow-up period after receiving a platelet rich plasma (PRP) injection, assessing changes in their pain…
- Conditions
- Osteoarthritis (OA), Osteoarthritis (OA) of the Knee, Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Shoulder
- Trial name
- PRP for MSK (NCT07231471)
- Testing
- Platelet Rich Plasma Injection, Platelet Rich Plasma Preparation
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Utah
Hallux Valgus
The Effect of Hallux Valgus Angle on Dynamic Knee Movement Pattern
Abstract Background/aim: Little is known about the relationship between hallux valgus and the alignment of proximal joints. Dynamic knee valgus is a movement pattern characterized by excessive knee abduction along with femoral…
- Trial name
- NCT06563037
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Achilles Tendinopathy, Flatfoot
Orthotics and Achilles Load in Runners
Compare Customized arch support orthoses (CASO) and orthotic heel lift (HL) on the effect of ATL in recreational runners with pronated feet.
- Conditions
- Achilles Tendinopathy, Flatfoot, Sports Injury
- Trial name
- NCT04003870
- Testing
- CASO, HL
- Where
- Hong Kong
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- North District Hospital
Wound Healing
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Single and Repeated Doses of Topical GSK1278863
This is a randomized, placebo-controlled, single-blind (subjects and investigators will be blinded, GSK internal personnel will not be blinded), parallel-group, two part (Part A, Part B) trial in healthy volunteers and subjects…
- Trial name
- NCT01831804
- Testing
- GSK1278863
- Where
- 7 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Diabetic Foot
Outpatient Treatment of Gram Positive Wound Infections in the Diabetic Foot: A Pharmaco-economic Comparison of Daptomycin vs. Vancomycin Based Regimens
The purpose of the study is to evaluate the overall burden to the participant (economic, quality of life, patients satisfaction and freedom from side effects) when treating Gram positive infections of the foot in diabetic adults…
- Trial name
- NCT01133600
- Testing
- Cubicin, Vancomycin
- Where
- 2 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Clinical Alliance for Research & Education - Infectious Diseases, LLC.
Diabetic Foot, Resistance Exercise
Breathing-based Leg Resistance Exercise Improves Wound Healing, Blood Sugar and Quality of Life for Diabetic Foot Ulcers
The purpose of the study was designed leg resistance training combined with breathing approach, and evaluated its effect on wound healing, blood sugar control and quality of life in type 2 diabetic patients with foot ulcers.
- Conditions
- Diabetic Foot, Resistance Exercise, Wound Healing, Hyperglycemia
- Trial name
- NCT05110092
- Testing
- leg resistance combined with breathing exercise training
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Diabetic Foot Ulcer Healing Trajectories
Efficacy of Negative Pressure Wound Therapy Versus Conventional Moist Dressings on Diabetic Foot Ulcer Healing Trajectories
Background: Diabetic foot ulcers (DFUs) are severe, chronic complications of diabetes carrying a high risk of amputation. While Negative Pressure Wound Therapy (NPWT) is an active biophysical treatment, clinical evidence using…
- Trial name
- DF-WOUND-RCT (NCT07745075)
- Testing
- Vacuum-Assisted Closure (VAC / NPWT)
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jerash Private University
Chronic Tendinopathy
Percutaneous Needle Tenotomy (PNT) Versus Platelet Rich Plasma (PRP) With PNT in the Treatment of Chronic Tendinosis
Tendinopathy is a clinical syndrome of chronic pain and tendon degeneration that impairs a person's ability to perform daily activities and recreation.
- Trial name
- NCT01833598
- Testing
- PNT + PRP, PNT alone
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Ingrown Toe Nail, Flat Foot
Association of Ingrown Toenails With Flat Foot, Hallux Abducto Valgus and Hallux Limitus
This study will have implications for any healthcare professionals who routinely manage ingrown toenails. Although different conservative and surgical treatment have been suggested, the recurrent rate is still high ranging from…
- Conditions
- Ingrown Toe Nail, Flat Foot, Hallux Abductovalgus, Hallux Limitus
- Trial name
- NCT03843177
- Testing
- No intervention
- Where
- Hong Kong
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Diabetic Foot Ulcer, Wound Healing
Systemic Biochemical Signature and Functional Quality Index of Calcaneal Bone Marrow Aspirate in Adults Undergoing Foot or Ankle Surgery
This observational prospective cohort study will evaluate whether routine blood tests are associated with the functional quality of calcaneal bone marrow aspirate mesenchymal stem cells in adults undergoing clinically indicated…
- Conditions
- Diabetic Foot Ulcer, Wound Healing, Foot Ulcer Due to Type 2 Diabetes Mellitus, Diabetes Mellitus Type 2
- Trial name
- IQF-BMA (NCT07802106)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Sao Francisco
Foot and Ankle Surgeries, Bunion
Efficacy of Tranexamic Acid in Foot and Ankle Surgeries
Epidemiology of foot and ankle surgeries that present to the hospitals in the US are often underestimated. However there has been growing emphasis on identification of these injuries and practice patterns.
- Trial name
- NCT03653429
- Testing
- Tranexamic Acid, Normal saline
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Healthy, Lower Limb Injury
Comparative Effect of Carbon Fiber Orthosis Cuff Design on Preference, Comfort, and Mechanics
Carbon fiber custom dynamic orthoses (CDOs) consist of a proximal cuff that wraps around the leg just below the knee, a posterior carbon fiber strut that stores and returns energy during gait, and a carbon fiber foot plate that…
- Conditions
- Healthy, Lower Limb Injury, Post-Traumatic Osteoarthritis
- Trial name
- AFOCUFF (NCT05456295)
- Testing
- Carbon Fiber Custom Dynamic Orthosis (CDO)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Wound Heal, Peripheral Artery Disease
Safety and Efficacy of the Noxsano Wound Care Bandage
This study is a prospective, interventional, non-randomized study designed to assess the safety and efficacy of the Noxsano Bandage (study device) in healthy subjects and wound care subjects with a diabetic lower extremity…
- Conditions
- Wound Heal, Peripheral Artery Disease, Ulcer, Leg, Ulcer Foot
- Trial name
- NCT04123093
- Testing
- Noxsano Bandage (Healthy Volunteers), Noxsano Bandage (Wound Care)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- OhioHealth
Diabetic Foot Ulcers, Wound Care
A Randomized Comparison of AmnioClear™ Human Allograft Amniotic Membrane vs. Moist Wound Dressing in the Treatment of Diabetic Wounds
This research project is testing a product called AmnioClear™ which is an amniotic membrane graft processed for Liventa Bioscience formerly AFCell Medical.
- Trial name
- NCT02120755
- Testing
- AmnioClear™ Human Allograft Amniotic Membrane
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Liventa Bioscience
Diabetes Mellitus, Healthy Volunteers
Impaired Wound Healing in Diabetic Foot Ulceration
An observational study to gather information about people who may have certain abnormalities in skin microcirculation and muscle metabolism and to determine whether these abnormalities affect wound healing.
- Trial name
- EPC (NCT00739323)
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Postural Balance, Foot Posture
Determination of the Degree of Dynamic Stability of the Foot in Single-leg Support in Relation to the Foot Posture Index in Judokas
The goal of this observational study is to examine the relationship between foot type and dynamic stability (balance while standing on one leg) in judo athletes.
- Conditions
- Postural Balance, Foot Posture, Sports Injuries, Athletic Performance
- Trial name
- NCT07417332
- Testing
- Postural and Balance Assessment
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Burns
Comparison of Mepitel Ag vs Antibiotic Ointment Used With Soft Cast Technique for Treatment of Pediatric Burns
The aim of this study is to compare Mepitel Ag to Triple antibiotic ointment impregnated Adaptic gauze when used with the soft cast technique to assess overall time to healing, yeast infection rate and parents perception of pain…
- Trial name
- NCT02681757
- Testing
- triple antibiotic ointment dressing, Mepitel Ag
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
VR Simulation in Diabetic Foot Wound Care Training, Moulage Simulation in Diabetic Foot Wound Care Training
Virtual Reality and Moulage Simulation in Diabetic Foot Wound Care Training
The goal of this randomized controlled clinical trial is to compare the effectiveness of virtual reality (VR) simulation, moulage simulation, and conventional training for diabetic foot wound care among nurses.
- Trial name
- VR (NCT07771062)
- Testing
- Training
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Other Instability, Ankle and Foot
Predicting Ankle Injury Through Clinical Functional Measures in Adolescent Athletes
The objective of this study is to determine if a clinical measure can be used effectively to predict ankle injury in high school and collegiate athletes across a variety of sports.
- Trial name
- NCT01658709
- Where
- United States
- Volunteers
- 377 people, healthy volunteers welcome
- Sponsor
- University of Toledo Health Science Campus