Clinical trials: Foot Injuries
DIABETES
Efficacy of Hyaluronic Acid Cream in Preventing Foot Ulceration Risk in Patients With Type 2 Diabetes and Moderate-to-Severe Peripheral Neuropathy: A Randomized Clinical Trial.
A triple-blind randomized clinical trial aimed at evaluating the efficacy of a hyaluronic acid cream in preventing foot ulcers in patients with type 2 diabetes and moderate-to-severe peripheral neuropathy.
- Trial name
- HIALU_PREV_FOO (NCT07131410)
- Testing
- Group hialuronyc
- Where
- Spain
- Volunteers
- 83 people
- Sponsor
- University of Malaga
Ulcer Foot, Ulcer Healing
Aquacel With Strengthening Fiber (WSF) Ribbon Dressings
Retrospective, multi-site, non-comparative, post-market study
- Conditions
- Ulcer Foot, Ulcer Healing, Wound Infection
- Trial name
- NCT07308665
- Testing
- Aquacel Ribbon
- Volunteers
- 214 people
- Sponsor
- ConvaTec Inc.
Wound Healing
Wound Treatment With 3% Sodium Pentaborate Pentahydrate
Chronic foot wounds which is very difficult to treat are common especially in diabetic and peripheral arterial or venous insufficiency patients.
- Trial name
- NCT02241811
- Testing
- 3% Sodium Pentaborate Pentahydrate
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- SB Istanbul Education and Research Hospital
Diabetic Foot Infection, Surgical Wound
Optimal Antibiotics for Operated Diabetic Foot Infections
Diabetic foot problems, especially infections (DFI), require multiple resources including iterative surgeries and amputations, long-lasting antibiotic therapies, education, off-loading and eventually revascularization and…
- Conditions
- Diabetic Foot Infection, Surgical Wound, Antibiotic Side Effect, Infection
- Trial name
- NCT04081792
- Testing
- Antibiotic therapy
- Where
- Switzerland
- Volunteers
- 643 people
- Sponsor
- Balgrist University Hospital
Chronic Skin Ulcer, Diabetic Foot Ulcer
Comparison of Platelet-Rich Plasma Dressing Versus Normal Saline Dressing for Chronic Non-Healing Ulcers
This randomized controlled trial will compare platelet rich plasma dressing with normal saline dressing for the treatment of chronic non healing cutaneous ulcers, including diabetic foot ulcers, venous leg ulcers, pressure…
- Trial name
- NCT07420868
- Testing
- Platelet Rich Plasma Dressing, Normal Saline Dressing
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Multan Medical And Dental College
Diabetes Mellitus, Ulcer Foot
Examining the Effectiveness of DermGEN™ in the Treatment of Diabetic Foot Ulcers in First Nations People
The study will examine the effectiveness of a decellularized dermal matrix (i.e., DermGEN™) in improving wound healing, quality of life and associated costs of treatment of DFUs in First Nations people living in the Northwestern…
- Conditions
- Diabetes Mellitus, Ulcer Foot, Ulcer Healing, Diabetic Foot Ulcer
- Trial name
- NCT05251480
- Testing
- Standard of Care, DermGEN™
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- DeCell Technologies Inc.
Foot Ulcer, Diabetic, Bacteria
Evaluation of Fluorescence-image Guided Wound Assessment vs. Standard Practice
The current trial aims to compare the assessment of diabetic foot ulcers by fluorescence image guidance to standard practice. The device will be used to acquire fluorescence images of diabetic foot ulcers: when wounds are…
- Trial name
- NCT02315092
- Testing
- Fluorescence Imaging
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University Health Network, Toronto
Wounds, Diabetic Foot Ulcers
Evaluation of a 'Hand-held' Fluorescence Digital Imaging Device for Real-Time Advanced Wound Care Monitoring (JDRTC/UHN)
We have developed an innovative optical molecular imaging platform (called PRODIGI) based on high-resolution fluorescence and white-light technologies in a hand-held, real-time, high-resolution, non-invasive format.
- Trial name
- JDRTC/UHN (NCT01651845)
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University Health Network, Toronto
Ischemia Limb, Diabete Mellitus
Comparative Study of Negative-Pressure Wound Therapy Integrated With Silver Nanoparticle Spray Versus Negative-Pressure Wound Therapy in Post-Revascularization Diabetic Foot Wound Management
This was a prospective, parallel-group, randomized controlled trial conducted at the Vascular Surgery Department of Kafrelsheikh University Hospital, Egypt.
- Trial name
- SNIPS-FOOT (NCT07147790)
- Testing
- After successful revacularization, We will categorize patients into two groups : groups A (The patient's wound will be cleaned and irrigated with silver nanoparticle spray, then we will cover the woun, Silver Nanoparticles Irrigant
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kafrelsheikh University
Ankle Fractures, Intermittent Pneumatic Compression
Preoperative Treatment of Malleolar Fractures
This study investigates, in a randomized setting, the use of intermittent in-cast pneumatic foot-compression (IPC) in the preoperative treatment of malleolar fractures.
- Conditions
- Ankle Fractures, Intermittent Pneumatic Compression, Comparative Study, Preoperative Care
- Trial name
- NCT02444468
- Testing
- Flowtron ACS800, Bandage
- Where
- Denmark
- Volunteers
- 96 people
- Sponsor
- Hospital of Southern Jutland
Chronic Wound, Burn Wound
Wound Healing Endpoint and Recurrence
This study is a continuation of a previously approved protocol conducted at Ohio State University and Indiana University. The first two aims of the original protocol have been completed, and this protocol will finish enrollment…
- Conditions
- Chronic Wound, Burn Wound, Diabetic Foot Ulcers, Pressure Ulcers
- Trial name
- NCT02577120
- Testing
- Epiceram Skin Barrier Function, Vaseline Petroleum Jelly
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Sashwati Roy
Ankle; Injury, Superficial, Multiple (With Foot)
The Foot and Ankle Ability Measure (FAAM) is Translated From English to Turkish and Assess the Validity and Reliability in Athletic Population Who Have Foot and Ankle Disorders.
Sport activity induces a relevant risk for lower extremities especially ankle and foot structures. Athletes who participate in basketball, volleyball and soccer are predisposed.
- Trial name
- NCT03259750
- Testing
- Foot and Ankle Ability Measure Turkish version (FAAM-T) questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Serkan Usgu
Diabetic Foot Ulcers
A Trial Examining Cellular Energetics Related to Various Wound Treatment Therapies
A randomized, controlled pilot study examining how cellular energetics related to various wound treatment therapies in patients with diabetic foot ulcers.
- Trial name
- NCT00605189
- Testing
- Powered Suction Pump (VAC Freedom), Powered Suction Pump, MWT
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- KCI USA, Inc
Diabetic Foot Ulcer, Foot Ulcer
A Study to Evaluate ENERGI-F703 GEL in Diabetic Foot Ulcer
This Phase 3 study is a randomized, double-blind, vehicle-controlled, multiple-center, parallel study to evaluate efficacy and safety of ENERGI-F703 GEL compared with vehicle control in subjects with Wagner Grade 1 to Grade 2…
- Conditions
- Diabetic Foot Ulcer, Foot Ulcer, Diabetes Mellitus, Wound
- Trial name
- NCT05930210
- Testing
- ENERGI-F703 GEL, ENERGI-F703 matched vehicle
- Where
- 24 sites in United States, Taiwan
- Volunteers
- 230 people
- Sponsor
- Energenesis Biomedical Co., Ltd.
VR Simulation in Diabetic Foot Wound Care Training, Moulage Simulation in Diabetic Foot Wound Care Training
Virtual Reality and Moulage Simulation in Diabetic Foot Wound Care Training
The goal of this randomized controlled clinical trial is to compare the effectiveness of virtual reality (VR) simulation, moulage simulation, and conventional training for diabetic foot wound care among nurses.
- Trial name
- VR (NCT07771062)
- Testing
- Training
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Foot Injuries, Posterior Tibial Tendon Dysfunction
The CurePPaC Study - Analysing Non-surgical Treatment Strategies to Cure Pes Planovalgus Associated Complaints
Pes planovalgus, also called flat foot, is a common foot deformity characterized by a flattening of the foot's longitudinal arch and is accompanied by a dysfunction of the posterior tibial tendon ("posterior tibial tendon…
- Trial name
- NCT01839669
- Testing
- Foot Orthoses Only, Foot Orthoses and Eccentric Exercise
- Where
- 6 sites in Switzerland
- Volunteers
- 7 people
- Sponsor
- Bern University of Applied Sciences
Musculoskeletal Pain, Musculoskeletal Injury
The Diagnostic Accuracy of the Clinical Examination
This study examines the diagnostic accuracy of the clinical examination as compared to MRI findings
- Trial name
- NCT03850470
- Testing
- clinical examination, MRI
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- High Point University
Diabetic Foot Ulcer, Pressure Ulcer
A Prospective, Open Label, Multicenter Trial for Evaluating the Efficacy of Treating and Managing Wounds in Elderly Population in Specialized Nursing Facilities Using RD1
The study is a prospective, single arm, multicenter efficacy study, consisting of 60 subjects who will complete the study (note: if any patients are lost to follow-up or withdrawn, enrollment will increase to compensate for loss…
- Conditions
- Diabetic Foot Ulcer, Pressure Ulcer, Venous Leg Ulcer, Trauma Injury
- Trial name
- NCT04577183
- Testing
- RD1 System
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- RedDress Ltd.
Soft Tissue Injuries
Effect of Negative Pressure Wound Therapy for Soft Tissue Injuries of Foot and Ankle in Patients at a Tertiary Care Hospital
Effect of Negative Pressure Wound Therapy for Soft Tissue Iinjuries of Foot and Ankle in Patients at a Tertiary care Hospital. To evaluate the effect of negative pressure wound therapy for soft tissue injuries of foot and…
- Trial name
- NCT04569305
- Testing
- Negative Pressure Wound Therapy, Conventional treatment
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Dow University of Health Sciences
Femoral Neck Fractures, Intertrochanteric Fractures
Opioid-Free Pain Treatment in Trauma Patients
Analgesic drug study that will compare pain outcomes of opioid analgesia and opioid-free analgesia in post-operative orthopedic patients.
- Conditions
- Femoral Neck Fractures, Intertrochanteric Fractures, Femoral Shaft Fracture, Distal Femur Fracture
- Trial name
- NCT06078371
- Testing
- Opioid-free pain treatment
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Kansas Medical Center