Clinical trials: Foot Pain
Morton's Neuroma, Pain Management
Cryoanalgesia for the Treatment of Pain in Subjects With Morton's Neuroma
This is a Proof-of-Concept Trial to define the safety, efficacy and feasibility of a cryoanalgesic device (iovera°®) for the treatment of pain in subjects diagnosed with Morton's Neuroma, who have failed conservative therapies.
- Trial name
- NCT05604144
- Testing
- Cryoanalgesia (iovera°®)
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Northern California Research Trials, Inc.
Patellofemoral Pain Syndrome
Foot Orthoses in Patellofemoral Pain Syndrome: a Prospective Randomized Study of Morpho-specific Versus Placebo Orthoses
Patellofemoral pain syndrome is one of the most common musculoskeletal disorders. It is defined as an anterior knee pain. Its origin is a conflict during patellar tracking, due to patellofemoral malalignment and soft tissue…
- Trial name
- NCT02250144
- Testing
- Foot orthoses
- Where
- 3 sites in France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Strasbourg, France
Liposomal Bupivacaine, Postoperative Pain
Liposomal Bupivacaine Versus Bupivacaine Plain for Operative Pain Management of Forefoot Surgery
Prospective, randomized, controlled single-blinded trial comparing liposomal bupivacaine with bupivacaine HCl for postoperative management.
- Conditions
- Liposomal Bupivacaine, Postoperative Pain, Forefoot Surgery, Opioid Use
- Trial name
- NCT04751344
- Testing
- Liposomal bupivacaine, Bupivacaine HCl
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alexandra Black
Hallux Valgus
Continuous Wound Infiltration After Hallux Valgus Surgery
The aim of this study is to investigate the effect of continuous wound infiltration with ropivacaine in comparison to standard pain management after elective distal metatarsal osteotomy for postoperative pain control.
- Trial name
- CWI-HVS (NCT02182999)
- Testing
- Wound infiltration catheter, NaCl 0.9%, Ropivacaine 0.2%
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University Innsbruck
Peripheral Arterial Disease
Foot Reflexology and Pain and Ankle Brachial Index and Walking Impairement
This randomized controlled study aimed to determine the effect of foot reflexology on pain, walking impairement and ankle brachial index level in patients with peripheral artery disease
- Trial name
- NCT06001203
- Testing
- Reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Baskent University
Plantar Fascitis
Percutaneous Needle Tenotomy Associated With Platelet-rich Plasma Injection Platelet-rich Plasma in the Treatment of Refractory Plantar Fasciitis: a Pilot Study of the Effect on Pain and Tolerance
There are various treatments for plantar fasciitis, including physical therapy, orthopedic inserts or steroid infiltrations. However, it is estimated that about 20% of patients do not respond to first-line treatment [Rompe…
- Trial name
- ANTILOPE (NCT05622279)
- Testing
- Percutaneous tenotomy + PRP
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Nantes University Hospital
Primary Body Region (Arranged Most Common to Least), Lumbar/SI
ATI Evidence-based Guide Investigating Clinical Services
The goal of this study is to evaluate how standard-of-care outpatient rehabilitation is delivered and how variation in care delivery mechanisms relates to clinical outcomes, service utilization, and value in patients receiving…
- Conditions
- Primary Body Region (Arranged Most Common to Least), Lumbar/SI, Knee, Shoulder
- Trial name
- AEGIS (NCT02285868)
- Where
- United States
- Volunteers
- 4,000,000 people, healthy volunteers welcome
- Sponsor
- ATI Holdings, LLC
Chronic Ankle Instability
Relationship of Dynamic Knee Valgus With Foot Posture, Pain, and Balance in Chronic Ankle Instability.
The purpose of the study is to identify if there is a relationship between the frontal plane projection angle as a measure of dynamic knee valgus with foot posture, pain, and dynamic balance in chronic ankle instability patients.
- Trial name
- DKV/CAI (NCT07121725)
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Cairo University
Hallux Valgus and Bunion (Disorder), Morton Neuroma
Feasibility of Specific Anesthesia of the Forefoot Preserving the Sensitivity of the Heel for Foot Surgery
Foot surgery is a painful surgery that is usually scheduled in outpatients. A good management of analgesia is the crucial point.
- Conditions
- Hallux Valgus and Bunion (Disorder), Morton Neuroma, Metatarsal Fracture, Ingrown Nail
- Trial name
- DISTIB (NCT03504462)
- Testing
- Specific block of medial and lateral plantar nerves
- Where
- France
- Volunteers
- 27 people
- Sponsor
- CMC Ambroise Paré
Morton's Neuroma
Comparison of Alcohol and Steroid Injection for Treating Morton's Neuroma
Interdigital neuroma is a painful forefoot disorder characterized by plantar pain and toe paresthesias thought to result from entrapment of the interdigital nerve by the overlying transverse metatarsal ligament.
- Trial name
- NCT00284583
- Testing
- Injection of Steroid into Foot, Injection of Alcohol into Foot, Injection of Lidocaine into Foot
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Brown University
Pain, Postoperative, Bunion
Safety and Efficacy Study of COV155 for Post-operative Bunionectomy Pain
The purpose of this study is to show the effectiveness of COV155 compared to placebo in subjects with acute moderate to severe pain following bunionectomy surgery.
- Trial name
- NCT01743625
- Testing
- COV155
- Where
- 5 sites in United States
- Volunteers
- 406 people
- Sponsor
- Mallinckrodt
Hallux Valgus
Acute Effects of Prolonged Walking on Hallux Valgus
Hallux valgus is a progressive foot deformity characterized by lateral deviation of the great toe and medial displacement of the first metatarsal head.
- Trial name
- NCT07177768
- Testing
- Prolonged walking
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Painful Diabetic Neuropathy, Diabetes
A Safety Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Painful Diabetic Neuropathy
Study CLO-311 is a multicenter, open-label, single-arm study to assess the long-term use of Clonidine Gel in the treatment of pain associated with PDN.
- Trial name
- NCT02355158
- Testing
- clonidine hydrochloride topical gel, 0.1%
- Where
- 20 sites in United States
- Volunteers
- 197 people
- Sponsor
- BioDelivery Sciences International
Hallux Valgus, Pain
Effects of Plantar Sensory Training in Individuals With Hallux Valgus.
Hallux valgus is a forefoot deformity with a high prevalence, which can progress to lateral deviation of the big toe, medial deviation of the first metatarsal, and subluxation of the first metatarsophalangeal joint in the future.
- Conditions
- Hallux Valgus, Pain, Balance; Distorted
- Trial name
- NCT05344755
- Testing
- Plantar Sensorial Training, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Renal Failure, Pain
Effect of Foot Bath on the Severity of Pain, Fatigue and Insomnia in Patients With Acute Renal Failure
One of the non-pharmacological methods that is easily applied, tolerated by the patient, and has no significant side effects is the foot bath.
- Trial name
- Foot Bath (NCT06613087)
- Testing
- Foot bath
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Amasya University
Palmar and Plantar Erythema, Numbness of the Four Limbs
Traditional Chinese Medicine Treatment for Capecitabine-Related Hand-Foot Syndrome
This study is a prospective, single-center, randomized, parallel-group, open-label clinical trial titled "Intervention with the 'Xu Xue Tong Luo Traditional Chinese Medicine Compound for Capecitabine-Related Hand-Foot Syndrome."…
- Conditions
- Palmar and Plantar Erythema, Numbness of the Four Limbs, Pain in the Distal Extremities, Peeling of the Soles and Palms
- Trial name
- NCT07883642
- Testing
- Twelve-Ingredient Prepared Sichuan Aconite Hand and Foot Bath, Standard Basic Nursing Interventions
- Volunteers
- 7 people
- Sponsor
- Emeishan Hospital of Traditional Chinese Medicine
Plantar Fasciopathy, Achilles Tendinopathy
QUANTIFY: Quantitative Understanding of Advanced Novel Techniques for Imaging Fasciitis and Yielding Biomarkers
This study is to create a test that can accurately find and measure the problem areas in muscle and fascia tissue, also known as myofascial pain.
- Conditions
- Plantar Fasciopathy, Achilles Tendinopathy, Controls
- Trial name
- QUANTIFY (NCT06803056)
- Testing
- Clinical exam, Ultrasound imaging, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Ruth Chimenti
Dystonia Disorder, Parkinson Disease
Botulinum Toxin Type A for Foot Dystonia-associated Pain in Parkinson's Disease
To study the effects of Botulinum toxin type A (BTXA) in the treatment of foot dystonia-associated pain in Parkinson's disease
- Trial name
- NCT04277247
- Testing
- Botulinum toxin type A
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Surgery
The Effect of Foot Reflexology on Patient Satisfaction, Pain, and Vital Signs After Abdominal Surgery
Reflexology practice is an effective method in pain control by stimulating the release of endorphins. The study was conducted to determine the effect of foot reflexology applied to patients undergoing abdominal surgery on pain…
- Trial name
- NCT05103163
- Testing
- Foot Reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Gurkan Kapikiran
Nursing Caries, Pain, Postoperative
Effect of Foot Bath on Postoperative Sleep Quality and Pain
One of the most common problems in patients in the postoperative period is pain and the associated deterioration in sleep quality. Deterioration in sleep quality can cause pain to be perceived more severely.
- Conditions
- Nursing Caries, Pain, Postoperative, Sleep Deprivation
- Trial name
- NCT05705908
- Testing
- Hot Foot Bath 1, Hot Foot Bath 2
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Acibadem University