Clinical trials: For Intervention
Mild Cognitive Impairment
Biodistribution of [11C]Acetoacetate/[18F]Fluorodeoxyglucose in Subjects With Risk Factors for Alzheimer's Disease
This is a single center imaging study that will recruit 60 participants who are enrolled in the Effect of a Ketogenic Diet on Alzheimer's Disease Biomarkers and Symptoms: Brain Energy for Amyloid Transformation in AD (BEAT-AD)…
- Trial name
- AcAc PET (NCT03130036)
- Testing
- [11C]Acetoacetate[18F]Fluorodeoxyglucose positron emission tomography scan
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Anxiety
Music-based Mindfulness Intervention for Elevated Race-based Anxiety in the Black Community
This study uses a multiple-baseline design and aims to replicate findings that a digital music-based mindfulness intervention can reduce elevated race-based state anxiety in Black Americans.
- Trial name
- NCT05746312
- Testing
- healing attempt
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Harvard University
Respiratory Distress Syndrome, Adult
Evaluating a Web-Based Ventilator Management Educational Program for Clinicians (The Lung Injury Knowledge Network [LINK] Study)
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a severe lung condition that causes respiratory failure. Individuals with ALI/ARDS often require the use of a respirator or artificial breathing machine, known…
- Trial name
- LINK (NCT00542737)
- Testing
- Web-Based Educational Program
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
MCI-AD, Early Stage Alzheimer's Disease
Development of a Novel Multidimensional Therapeutic Intervention Protocol for MCI
As populations age, Alzheimer's disease (AD) is increasing while disease-modifying drugs remain elusive, making early diagnosis and intervention essential.
- Trial name
- NCT07196592
- Testing
- Olfactory stimulation, Temporal Interference,TI, Olfactory-TI Stimulation
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Yuan Shen
Anxiety
Early Intervention AND NURSING Support for an " Involuntary Commitment Procedure " for a Close Relative
In a context of first hospitalization under the constraint of a relative in psychiatric emergencies: effect of an early intervention and a 6-month nursing follow-up on the anxious experience of third party persons effect of…
- Trial name
- Vécu/Tiers/Psy (NCT03510039)
- Testing
- Early device / Follow up, Usual care
- Where
- France
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Intervention Adoption, Implementation
Beliefs and Attitudes for Successful Implementation in Schools (BASIS)
The goal of this study is to adapt and test the feasibility and potential efficacy of a theory-driven pre-implementation intervention to address individual-level barriers to EBP implementation - Beliefs and Attitudes for…
- Trial name
- NCT03791281
- Testing
- BASIS, Attention Control
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pain Control in Heel Prick Procedure
Comparing 0.2 ml and 0.5 ml Oral 24% Sucrose Solution for Pain Relief During Heel Prick in Neonates With Historical Controls
The goal of this clinical trial is to determine whether a lower dose of oral 24% sucrose solution provides pain relief that is non-inferior to a higher dose during routine heel-prick procedures in term neonates.
- Trial name
- Sucrose (NCT07784322)
- Testing
- 24% oral sucrose
- Where
- Hong Kong
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kwong Wah Hospital
Knee Osteoarthristis
Study of Wearable Interventions for Improving Mobility of Individuals With Knee Osteoarthritis
Knee osteoarthritis (OA) affects an estimated 654 million people over age 40 world-wide. In the United States, approximately 16% of adults over the age of 40 have knee OA.
- Trial name
- NCT07652437
- Testing
- Dephy Exoboot
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Complication of Surgical Procedure, Infections
Pathogenesis of Postoperative Infections and Biomarkers for Early Diagnosis of it
Infections remain a prevalent complication after major abdominal surgery. The common belief that most surgical site infections (SSIs) following elective surgery with modern antiseptic techniques are due to intraoperative…
- Trial name
- NCT06513598
- Testing
- Major visceral surgery for gastrointestinal cancer
- Where
- 2 sites in Lithuania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos
Pain, Chronic, Fatigue Syndrome, Chronic
Activate For Life: mHealth Intervention To Address Pain And Fatigue In Low-income Older Adults Aging In Place
The Overall Aim of the present proposal is to evaluate the feasibility of an integrated mind-body intervention, Activate for Life, to improve overall physical activity and mental health and reduce pain and fatigue, resulting in…
- Conditions
- Pain, Chronic, Fatigue Syndrome, Chronic, Aging
- Trial name
- Activate (NCT03853148)
- Testing
- Otago, Gentle yogic breathing, Behavioral Activation
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Professional Fulfillment, Professional Identity Formation
A Professional Development Programme (ProDeveloP) for Newly Graduated Nurses
This clinical study aims to implement and evaluate a professional development programme (ProDeveloP) designed to facilitate the transition of newly graduated nurses (NGNs) into their new roles.
- Conditions
- Professional Fulfillment, Professional Identity Formation, Professional Quality of Life, Support Program
- Trial name
- NCT06742047
- Testing
- Professional development programme
- Where
- Sweden
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Mälardalen University
Tissue and Organ Procurement
Online Intervention for ANHPI College Students
Taking advantage of college students' frequent use of online technology, including social networking sites (e.g., Instagram a social media site /Facebook a social networking site) and social media sites (e.g., YouTube), the…
- Trial name
- iDecide (NCT02318849)
- Testing
- Web intervention
- Where
- United States
- Volunteers
- 4,827 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Tobacco Use Cessation, Cigarette Smoking
Innovative Web-Based Intervention for Smoking Cessation Among College Students
Tobacco use is the leading cause of cancer death in the U.S. Because smokers who quit by age 30 have cancer death risk similar to non-smokers, promoting cessation early in life is critical. U.S.
- Trial name
- NCT01982825
- Testing
- Online intervention arm, Online control arm
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Emory University
Sexual Health, Education, Health
Health Education and Relationships Through Theater: An RCT of Promoting Awareness Through Live Movement and Sound for Youth With Autism Spectrum Disorder (PALMS-ASD)
Teens with ASD ages 14-19 will be screened for eligibility, complete a baseline interviewer/ACASI-administered survey, and randomly assigned to either intervention or control group. The enrollment goal is 500 teens.
- Trial name
- HEART (NCT04005547)
- Testing
- Promoting Awareness through Live Movement and Sound for youth with Autism Spectrum Disorder
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Public Health Management Corporation
Stroke, Ischemic, Hemianopia, Homonymous
Statistical Learning as a Novel Intervention for Cortical Blindness
This project aims to develop a novel visual training paradigm for use in visually-intact participants and those sufferings from stroke-induced visual impairments.
- Conditions
- Stroke, Ischemic, Hemianopia, Homonymous, Hemianopsia, Occipital Lobe Infarct
- Trial name
- NCT06578117
- Testing
- Vision Training and Learning Task
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Suicide Prevention
Efficacy-Implementation Study for PC CARES in Rural Alaska
This participatory, pragmatic efficacy-implementation trial evaluates the impact of Promoting Community Conversations About Research to End Suicide (PC CARES) to evaluate Learning Circle (LC) participant outcomes (AIM#1)…
- Trial name
- NCT06658808
- Testing
- Promoting Community Conversations About Research to End Suicide
- Where
- 2 sites in United States
- Volunteers
- 1,075 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Physical Activity, Patient Engagement
Active KC: a Text Message Based Intervention for Physical Activity
Active KC will involve delivering PA support tools to individuals interested in increasing their physical activity. The tools involve provision of a Garmin wearable activity monitor and participant-tailored behavior change…
- Trial name
- NCT05110508
- Testing
- Text Based Behavioral Intervention for Physical Activity
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Grief Disorder, Prolonged
Feasibility and Efficacy of Individual SH+ Intervention
The central aim of this research is to execute a randomized controlled trial (RCT) to assess the impact and effectiveness of the individually-delivered SH+ intervention among earthquake survivors in Türkiye.
- Trial name
- NCT06091540
- Testing
- Feasibility and Efficacy of Individual SH+ Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Koç University
Healthy
The ILLUMINATE Study
The research study will be conducted to obtain baseline, or "normative" information to compare an air charged HRAM catheter to traditional solid catheter measures using the IAPWG standardized testing protocol and London…
- Trial name
- ILLUMINATE (NCT06805240)
- Testing
- Air Charged Catheter ARM Procedure, Solid State Catheter ARM Procedure
- Where
- 3 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Laborie Medical Technologies Inc.
Mood Change, Depressive Symptoms
Mind-Body Skills Group for Graduate Students
Integrative-Mind-Body Skills Group (I-MBS-G) is an 8-week group that teaches skills to build inner resources for effective mood management.
- Conditions
- Mood Change, Depressive Symptoms, Anxiety Generalized
- Trial name
- NCT05447689
- Testing
- Integrative-Mind-Body Skills Group
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
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