Clinical trials: For Intervention
Psychotic Disorders, Schizophrenia Spectrum Disorders
Feasibility, Acceptability, and Preliminary Efficacy of Yoga-based Group Intervention for Outpatients With Schizophrenia Spectrum Disorders
A three-arm pilot rater-blinded randomized controlled trial is conducted, comprising Yoga-based Group Intervention (YoGI + TAU) as the experimental condition, a strength and flexibility training (SFT + TAU) group, and treatment…
- Trial name
- YOGIA (NCT07455929)
- Testing
- Yoga-based Group Intervention (YoGI) and treatment as usual (TAU), Strength and Flexibility Training (SFT) and TAU
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
Obstructive Sleep Apnea
Lifestyle Intervention Treatment for Patients With Mild Obstructive Sleep Apnea
The main objective of the study is to determine whether a supervised lifestyle intervention including individualized dietary counseling could be a curative treatment for patients with mild OSA.
- Trial name
- NCT00486746
- Testing
- Lifestyle intervention (physical activity and dietary counseling), General information on healthy lifestyle habits
- Where
- Finland
- Volunteers
- 81 people
- Sponsor
- Kuopio University Hospital
Problem Behaviors, Attention Deficit Hyperactivity Disorder
Mental Health Services for Foster and Adopted Children
This study will determine the effectiveness of a relationship-based intervention in improving the interaction between caregivers and young children placed in their care.
- Conditions
- Problem Behaviors, Attention Deficit Hyperactivity Disorder, Depression
- Trial name
- NCT00056303
- Testing
- Attachment and Biobehavioral Catch-up, Developmental Education for Families
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Delaware
Developmental Language Disorder
Syntactic Intervention for Cantonese-speaking Children With DLD
The goal of this clinical trial is to compare the efficacy of explicit vs. implicit intervention on subject relative clause production in Cantonese-speaking children with Developmental Language Disorder (DLD).
- Trial name
- NCT06954194
- Testing
- Explicit intervention (Shape Coding+syntactic priming), Implicit intervention (syntactic priming only)
- Where
- Hong Kong
- Volunteers
- 32 people
- Sponsor
- The Hong Kong Polytechnic University
Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Female
Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes
The goal of this clinical trial is to determine the effectiveness of using a freeze-dried wild blueberry powder on cardiometabolic health, cognitive function, and gut microbiota composition in adult women with prediabetes.
- Conditions
- Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Female, Adult, Endothelial Function (Reactive Hyperemia)
- Trial name
- NCT06735651
- Testing
- Wild Blueberry
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Georgia State University
Blood Pressure, Sleep
Multidimensional Sleep Health Intervention for Couples
The goal of this pilot dyadic study is to adapt a multidimensional sleep health (MDSH) intervention, previously disseminated at the individual level, for relationship partners, determine whether it improves sleep health and…
- Conditions
- Blood Pressure, Sleep, Cardiovascular Health
- Trial name
- DREAM-COUPLES (NCT07603245)
- Testing
- Multidimensional Sleep Health Promotion Intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Columbia University
Surgical Release of Ai Pulley Trigger Finger
Ultrasound Guided A1 Pulley Release For The Treatment of Trigger Finger
In this randomized, prospective clinical trial, patients with trigger finger or trigger thumb, will be treated with two different methods; ultrasound-guided release of the first annular pulley or open surgical release of A1…
- Trial name
- NCT02830672
- Testing
- Surgical release A1 pulley for Trigger finger of the hand
- Volunteers
- 60 people
- Sponsor
- National and Kapodistrian University of Athens
Chronic Pain
Singing for Chronic Pain, a New Intervention for the Management of Chronic Pain
The aim of the project is to determine the feasibility of delivering a Singing for Chronic Pain (SCP) programme to patients with chronic pain attending a pain clinic.
- Trial name
- NCT04111861
- Testing
- Singing
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Royal Cornwall Hospitals Trust
Depression, Anxiety, Mental Health Issue
Clinical Outcomes of a Digital Mental Health Intervention for Moderate/Severe Depression and Anxiety
A digital mental health intervention (BetterHelp, Mountain View, CA) provides users with access to online therapy care for treatment of depression and anxiety.
- Conditions
- Depression, Anxiety, Mental Health Issue, Mental Health Wellness 2
- Trial name
- NCT07081061
- Testing
- BetterHelp
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Teladoc Health
Anesthesia, Spinal, Prilocaine
Prilocaine for Spinal Anesthesia in Ambulatory Setting
The purpose of this study is to retrospectively analyze data from more than 3000 procedures, to better define the safety profile of spinal prilocaine and the incidence of complications and side effects.
- Conditions
- Anesthesia, Spinal, Prilocaine, Ambulatory Surgical Procedures
- Trial name
- NCT04161586
- Testing
- Prilocaine Hydrochloride
- Where
- Italy
- Volunteers
- 3,291 people
- Sponsor
- Ospedale di Circolo - Fondazione Macchi
Geographic Atrophy
A Study to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
The purpose of this study is to evaluate change in geographic atrophy (GA) lesion growth of eyes treated with JNJ-81201887 compared to sham control.
- Trial name
- NCT05811351
- Testing
- JNJ-81201887, Prednisone, Triamcinolone
- Where
- 162 sites in United States, Australia and 15 more
- Volunteers
- 305 people
- Sponsor
- Janssen Research & Development, LLC
Non-Small Cell Lung Cancer (NSCLC)
Digital Lifestyle Intervention for Lung Cancer Survivors
The aim of this study is to assess the efficacy of a digital lifestyle intervention in non-small cell lung cancer (NSCLC) survivors on health-related quality of life (HRQoL) over three months.
- Trial name
- QUALUCA (NCT05819346)
- Testing
- Lifestyle
- Where
- 4 sites in Switzerland
- Volunteers
- 21 people
- Sponsor
- Kai-Uwe Schmitt, PhD, MEng, ICID
Rumination, Stress, Psychological
Testing a Digital Intervention for Adolescents
Teen participants (ages 13-17) will be randomly assigned to either an experimental (the Happify Teens digital platform), or a waitlist control group. The study includes an 8-week intervention period and a 1-month follow up period.
- Trial name
- NCT04567888
- Testing
- Happify Teens
- Where
- United States
- Volunteers
- 353 people
- Sponsor
- Happify Inc.
Suicide Prevention
Brief Suicide Intervention for Youth in Juvenile Detention Settings
This is an intervention development study and therefore is not designed or powered to test hypotheses. Following initial development and refinement of intervention and protocol, an open trial will be conducted at one juvenile…
- Trial name
- NCT05225103
- Testing
- SAFETY-Acute intervention
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Duke University
Gastroparesis Postoperative, Delayed Gastric Emptying Following Procedure
Acupuncture for Postoperative Gastric Emptying Delay
This multicenter clinical trial, conducted at Qilu Hospital of Shandong University and collaborating institutions, prospectively assesses the efficacy and safety of acupuncture for postoperative delayed gastric emptying.
- Trial name
- APOGEE (NCT07505927)
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Qilu Hospital of Shandong University
Osteoarthritis
Yoga as an Intervention for Women With Knee Osteoarthritis
Keeping individuals with knee osteoarthritis physically active is critically important. Exercise is effective at reducing pain while improving physical function.
- Trial name
- NCT02146105
- Testing
- Yoga For Knee Osteoarthritis
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- McMaster University
Acquired Immunodeficiency Syndrome, HIV Infections
Computer-Assisted Adherence Program for Patients Taking Anti-HIV Drugs
The purpose of this study is to evaluate the effectiveness of a computer-assisted, self-administered adherence program for patients on complicated anti-HIV drug regimens.
- Trial name
- NCT00051766
- Testing
- Computer-based Intervention
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Traumatic Brain Injury, Depression
A Trial of Two On-Line Interventions for Child Brain Injury
The primary aims of this project are to examine the feasibility and relative efficacy of two models of on-line intervention for families of children with traumatic brain injury: one, a model emphasizing cognitive appraisals and…
- Conditions
- Traumatic Brain Injury, Depression, Anxiety Disorders
- Trial name
- NCT00178022
- Testing
- Case management and problem solving therapy
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Smoking Cessation, Tobacco Smoking
App for Pregnancy Smoking Cessation With Peer Support
The objectives of this project are to develop, implement, and test the feasibility and effectiveness of an artificial intelligence adaptive mobile pregnancy tobacco cessation app-based intervention using deep tailoring and a…
- Trial name
- SFT (NCT05337722)
- Testing
- SFT 2.0, Active control
- Where
- Romania
- Volunteers
- 786 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Stroke, Hypertension
BRIDGE: Blood Pressure Reduction and Intervention Delivery Via Group Engagement
The investigators want to improve care for people who have had a stroke. High blood pressure is the leading cause for having a second stroke and can lead to poor brain health.
- Conditions
- Stroke, Hypertension, Home Blood Pressure Monitoring, Implementation Research
- Trial name
- BRIDGE (NCT07091851)
- Testing
- Group medical visits and home blood pressure monitoring
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
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