Clinical trials: For Intervention
Pain, Pain Management
Immersive Virtual Reality Intervention for Non-Opioid Pain Management: A Randomized Controlled Trial
The study is a randomized controlled trial (RCT) of VR non-opioid management vs. a control "sham" intervention for a broad and representative group of medical and surgical patients with pain.
- Trial name
- NCT02887989
- Testing
- Virtual Reality, Health and Wellness Channel
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Cedars-Sinai Medical Center
Lymph Node Resection
Use of Tachosil® for Lymph Sealing During Surgery
The purpose of this study is to describe effectiveness and reliability of TachoSil® in lymph sealing after lymphadenectomy.
- Trial name
- SEAL (NCT01920958)
- Testing
- TachoSil®
- Where
- Germany
- Volunteers
- 233 people
- Sponsor
- Takeda
Crisis Intervention, Suicide and Depression
Brief Online Help-seeking Barrier Reduction Intervention
Objective: Mental illness is a leading cause of disease burden; however, many barriers prevent people from seeking mental health services.
- Trial name
- NCT03633825
- Testing
- Brief help-seeking barrier reduction intervention
- Where
- United States
- Volunteers
- 39,450 people, healthy volunteers welcome
- Sponsor
- Harvard University
Atopic Dermatitis, Atopic Hand Eczema
A 32-week Trial to Evaluate the Efficacy and Safety of Tralokinumab in Subjects With Moderate-to-severe Atopic Hand Eczema Who Are Candidates for Systemic Therapy
The purpose of this study is to test if treatment with tralokinumab is safe and efficacious in treating moderate-to-severe atopic hand eczema.
- Trial name
- ADHAND (NCT05958407)
- Testing
- Tralokinumab
- Where
- 69 sites in United States, Belgium and 8 more
- Volunteers
- 235 people
- Sponsor
- LEO Pharma
Post Surgical Neuropathic Pain
Comparison of Qutenza (8% Capsaicin) With a Low-dose Capsaicin for Treatment of Nerve Pain After Surgery
This is an interventional, Phase III, double-blind, randomized, controlled, parallel-group, multi-site, clinical trial to confirm the efficacy and safety of repeated topical application of Qutenza (capsaicin 8% topical system)…
- Trial name
- RISE (NCT04967664)
- Testing
- Qutenza (capsaicin) 8% topical system, capsaicin 0.04% topical system
- Where
- 64 sites in United States, France and 4 more
- Volunteers
- 412 people
- Sponsor
- Averitas Pharma, Inc.
Food Insecurity
CommunityRx-Hunger
CommunityRx-Hunger (CRx-H) is a hospital-based intervention that addresses food insecurity and other health-related social needs such as transportation, housing, utilities, and safety.
- Trial name
- CRx-H (NCT04171999)
- Testing
- Community Rx-Hunger (CRx-H)
- Where
- United States
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Advanced Solid Tumor Diseases
Trial of Individual Psychosocial Interventions for Cancer Patients
The aim of the study is to compare the benefits of three types of individual treatment programs for cancer patients: Meaning-Centered counseling, Supportive counseling, and Enhanced Usual Care.
- Trial name
- NCT01323309
- Testing
- Individual Meaning-Centered Psychotherapy (IMCP), standard Individual Supportive Psychotherapy (ISP), enhanced usual care (EUC)
- Where
- United States
- Volunteers
- 346 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Chronic Liver Disease, Thrombocytopenia
Safety and Efficacy Study of Lusutrombopag for Thrombocytopenia in Patients With Chronic Liver Disease Undergoing Elective Invasive Procedures
The primary purpose of this study is to compare the efficacy of lusutrombopag with placebo for the treatment of thrombocytopenia in patients with chronic liver disease who are undergoing elective invasive procedures.
- Trial name
- L-PLUS 2 (NCT02389621)
- Testing
- Lusutrombopag
- Volunteers
- 215 people
- Sponsor
- Shionogi
Lower Extremity Occlusive Disease
Safety and Efficacy of Computer Assisted Surgery for Use in Vascular Surgery Procedures
The purpose of this study is to evaluate the preliminary safety and efficacy of the daVinci surgical system (computer-assisted surgery) for use in vascular surgery procedures.
- Trial name
- NCT01136811
- Testing
- Computer assisted surgery
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- University of Chicago
Thrombosis
Pharmacokinetic, Pharmacodynamic, Safety, and Efficacy Study of Rivaroxaban for Thromboprophylaxis in Pediatric Participants 2 to 8 Years of Age After the Fontan Procedure
The Purpose of this study is to characterize the single and multiple-dose pharmacokinetic (PK) and pharmacokinetic/pharmacodynamic (PK/ PD) profiles after oral rivaroxaban therapy administered to pediatric participants 2 to 8…
- Trial name
- UNIVERSE (NCT02846532)
- Testing
- Rivaroxaban, Acetylsalicylic Acid
- Where
- 42 sites in United States, Argentina and 8 more
- Volunteers
- 112 people
- Sponsor
- Janssen Research & Development, LLC
Any Ear Nose or Throat Conditions, With Identified Need for a Diagnostic Procedure or Surgery on or Through the Mucous Membranes of the Nasal Cavities
Topical Application of Cocaine HCl 4%, or 10%, or Placebo Solution in Local (Topical) Anesthesia
Randomized, prospective, multi-center, double blind placebo-controlled parallel group study of a Placebo Topical Solution versus Cocaine HCl 4% Topical Solution for safety and efficacy, and Cocaine HCl 4% and 10% Topical Solution…
- Trial name
- NCT02500836
- Testing
- Cocaine HCl 4% Topical Solution, Cocaine HCl 10% Topical Solution
- Where
- United States
- Volunteers
- 646 people, healthy volunteers welcome
- Sponsor
- Lannett Company, Inc.
Physical Activity, Blood Pressure
Multilevel Intervention for Physical Activity in Retirement Communities
The purpose of this study was to assess whether a 6-month multilevel physical activity intervention can significantly increase physical activity levels in sedentary adults, 65 and older, living in Continuing Care Retirement…
- Conditions
- Physical Activity, Blood Pressure, Physical Functioning, Quality of Life
- Trial name
- MIPARC (NCT01155011)
- Testing
- Physical Activity, Group educational sessions, Phone counseling call
- Where
- United States
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Sleep Apnea
Telemedicine Interventions for Obstructive Sleep Apnea (OSA)
This project is investigating whether both moderate-intensity physical activity and dietary weight loss will independently reduce sleep apnea symptoms and improve quality of life.
- Trial name
- NCT01108081
- Testing
- Physical activity, Diet, Health education
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- VA Office of Research and Development
Alcohol Use Disorder
EMA/EMI for Psychiatrically Hospitalized Emerging Adults Who Drink to Cope
The goal of this proposed study is to evaluate an ecological momentary assessment plus an ecological momentary intervention (EMA+EMI) for emerging adults in a psychiatric partial hospitalization program who drink to cope with…
- Trial name
- NCT05074030
- Testing
- Personalized Normative Feedback, Coping-Motive Specific Personalized Feedback Intervention plus an Ecological Momentary Intervention (PFIcope+EMI)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Butler Hospital
Cardiac Surgery, Older Adults
Behavioral Activation and Medication Optimization In Older Adults Undergoing Cardiac Procedures
This Hybrid 1 Study will test the effectiveness of a bundled intervention comprised of behavioral activation and medication optimization in reducing symptoms of depression and anxiety in older adults undergoing cardiac surgery…
- Conditions
- Cardiac Surgery, Older Adults, Depression, Anxiety
- Trial name
- NCT05575128
- Testing
- Behavioral activation, Medication optimzation, Care as usual
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Washington University School of Medicine
Gulf War, Fatigue
Groups for Regaining Our Wellbeing
This study is a randomized clinical trial measuring outcomes up to 6-months post-intervention. The objective of this study is to evaluate outcomes of two different group interventions for Veterans with Chronic Multisymptom…
- Conditions
- Gulf War, Fatigue, Pain, Depression
- Trial name
- GROW (NCT03058952)
- Testing
- Mindfulness-Based Stress Reduction, Chronic Disease Self-Management Program
- Where
- United States
- Volunteers
- 245 people
- Sponsor
- VA Office of Research and Development
Asthma
Investigation of the Role of Pictorial Asthma Action Plans to Promote Self-management in Rural Youth With Asthma
The aim of this study is to investigate the potential benefit of Pictorial versus Written Asthma Action Plans (AAPs) to support asthma management among young people with persistent asthma.
- Trial name
- TAAC (NCT03187119)
- Testing
- Pictorial Asthma Action Plan, Written Asthma Action Plan
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- West Virginia University
Acute Coronary Syndromes
A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart
The purpose of this study is to determine if Apixaban is safer than a Vitamin K Antagonist given for 6 months in terms of bleeding in patients with an irregular heart beat (atrial fibrillation) and a recent heart attack or a…
- Trial name
- NCT02415400
- Testing
- Apixaban, vitamin K antagonist, Acetylsalicylic acid
- Where
- 626 sites in United States, Argentina and 35 more
- Volunteers
- 4,614 people
- Sponsor
- Bristol-Myers Squibb
Hemophilia A
A Study of TAK-660 in Surgical Procedures for People With Hemophilia A.
This study is about a factor VIII medicine called Adynovate (TAK-660) used during surgery for people with hemophilia A who have low blood levels of factor VIII.
- Trial name
- NCT04941898
- Testing
- PEGylated Recombinant Factor VIII
- Where
- Japan
- Volunteers
- 16 people
- Sponsor
- Takeda
Suicide, Attempted, Suicide and Self-harm
Real-time Intervention for Suicide Risk Reduction: Primary Open Pilot
The goal of this study is to provide an initial pilot test of an Ecological Momentary Intervention (EMI) designed the reduce the distress associated with negative emotion among individuals at risk for suicide that pairs content…
- Trial name
- NCT03950765
- Testing
- Ecological momentary intervention
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Rutgers, The State University of New Jersey
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