Clinical trials: For Intervention
Adolescent, Bullying
Online Bullying Bystander Intervention for Middle Schools Phase II
School interventions to reduce bullying can be effective but also require substantial time and resources. Online technologies have the potential to deliver effective bullying interventions to a large number of middle school…
- Conditions
- Adolescent, Bullying, Technology, Mental Health
- Trial name
- STACII (NCT05572398)
- Testing
- STAC-T
- Where
- 2 sites in United States
- Volunteers
- 613 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Smoking Cessation, Marijuana Use
Project CheckUP: A Brief Behavioral Intervention for Quitline Callers Who Use Marijuana (MJ) and Tobacco
Smoking cigarettes remains the number one preventable cause of death and disease in the US. Smokers who call tobacco quitlines and use marijuana struggle to quit tobacco due to the interactive effects of nicotine and marijuana.
- Trial name
- NCT04737772
- Testing
- Behavioral: Quitline treatment as usual, QL Marijuana Check-Up intervention (QL-MJCU)
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Consumer Wellness Solutions
Insomnia, Depression
Adjunctive Brief Behavioral Treatment of Insomnia (BBTI) for Sleep Intervention (SI)
There is a strong association between sleep disturbance and suicidal thoughts and behaviors. Sleep disturbance is also highly comorbid with other common conditions associated with suicide such as depression and posttraumatic…
- Conditions
- Insomnia, Depression, Posttraumatic Stress Disorder, Suicidal Ideation
- Trial name
- NCT02248675
- Testing
- CBT-I, TAU
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- VA Office of Research and Development
Prostate Cancer
Prostate Cancer Intervention Versus Observation Trial (PIVOT)
Radical prostatectomy provides potentially curative removal of the cancer. However, it subjects patients to the morbidity and mortality of the surgery and may be neither necessary nor effective.
- Trial name
- PIVOT (NCT00007644)
- Testing
- Radical prostatectomy
- Where
- 31 sites in United States
- Volunteers
- 731 people
- Sponsor
- VA Office of Research and Development
Unemployment, Hazardous Drinking
Interventions for Unemployed Hazardous Drinkers
Despite recent improvements in the US economy, unemployment remains a significant concern, and estimates indicate that one-third of unemployed persons drink at hazardous levels, adversely impacting their health and abilities to…
- Trial name
- NCT02559609
- Testing
- Contingency management for alcohol abstinence, Contingency management for completing job related activities, Job relelated activity contracting
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- UConn Health
Conscious Sedation, Simple Lacerations Less Than 4 cm
A Comparison of Intranasal Midazolam and Nitrous Oxide (N2O) Minimal Sedation for Minor Procedures in a Pediatric Emergency Department
The objective of this project is to compare the sedative effects of intranasal midazolam versus inhaled nitrous oxide (N2O) for minor procedures in the pediatric emergency department.
- Conditions
- Conscious Sedation, Simple Lacerations Less Than 4 cm, Lumbar Punctures, Minor Incision Drainage of Abscesses Not Requiring Extensive Debridement
- Trial name
- NCT03085563
- Testing
- Nitrous Oxide, Midazolam
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Colorado, Denver
Alcohol Use Disorder
Brief Online Interventions for Alcohol Use
The purpose of this study is to test the feasibility and acceptability of delivering cognitive training over mTurk. Subjects will be randomized to a 1) inhibitory control training condition, 2) working memory training condition…
- Trial name
- NCT03438539
- Testing
- Normative Feedback, Inhibitory Control Training, Working Memory Training
- Where
- United States
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- Craig Rush
Neck Pain
Benefit of Adding Stretching to Standard Intervention For Patients With Nonspecific Mechanical Neck Pain
The purpose of this study is to assess the benefit of adding stretching exercises to cervical mobilization and cervical range of motion exercises on cervical range of motion, pain, pain threshold, level of disability and patient…
- Trial name
- NCT03194490
- Testing
- combined intervention group, The standard intervention
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Insufficient Physical Activity
A BCT Intervention for Physical Activity Among Individuals on Statins
The purpose of this project is to identify the minimum effective dose (MED) of a multi-component behavioral change intervention required to increase levels of physical activity (PA) among participants on primary prevention statin…
- Trial name
- NCT05273723
- Testing
- 5 Behavioral Change Techniques
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Stress Disorders, Post-Traumatic, Alcohol-Related Disorders
Primary Care Treatment Integrating Motivation and Exposure
This project aims to develop and test an integrated brief intervention to reduce heavy alcohol use and PTSD severity in veterans receiving Veterans Affairs Primary Care.
- Trial name
- PC-TIME (NCT03812146)
- Testing
- PC-TIME, PC-TAU
- Where
- 2 sites in United States
- Volunteers
- 63 people
- Sponsor
- Syracuse VA Medical Center
Dementia
Palliative Care at Home for Dementia
The proposed project is a randomized controlled trial of a new home-based palliative care program for adults with advanced dementia and their caregivers within the Mount Sinai Health System.
- Trial name
- NCT03798327
- Testing
- Home Palliative Care
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Stroke, Acute
Solitaire FR Thrombectomy for Acute Revascularisation
The objective of this study was to obtain prospective clinical data on the safety and efficacy of the Solitaire™ FR device for patients diagnosed with acute ischemic stroke.
- Trial name
- STAR (NCT01327989)
- Testing
- Solitaire™ FR device
- Where
- 2 sites in Switzerland
- Volunteers
- 202 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Alzheimer Disease
Caregiver Speaks: A Technologically Mediated Storytelling Intervention
Caregiver speaks is a randomized trial of a Photo elicitation intervention for caregivers of Alzheimers patients.
- Trial name
- NCT04103580
- Testing
- Photo elicitation
- Where
- United States
- Volunteers
- 457 people
- Sponsor
- Washington University School of Medicine
Pancreatitis, Diabetes
Sitagliptin Therapy to Improve Outcomes After Islet Autotransplant
The purpose of the study is to test the effects of sitagliptin on the need for insulin (the hormone that lowers blood sugars) by patients who receive a pancreatectomy and islet autotransplant for chronic pancreatitis.
- Trial name
- NCT01186562
- Testing
- Sitagliptin
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- University of Minnesota
Pain
Evaluation of Risk Minimization, Assessment and Outcomes in Patients With Chronic Pain Taking Avinza
The purpose of this study is to provide information in a broad, "real world" population of chronic pain patients assessing both pain control with AVINZA as well as the potential risk for misuse and abuse.
- Trial name
- ACCESS 2008 (NCT00640042)
- Testing
- morphine sulfate extended release capsules
- Where
- 384 sites in United States, Puerto Rico
- Volunteers
- 1,570 people
- Sponsor
- Pfizer
Neck Pain, Pain in Arm, Unspecified
Manual Cervical Distraction: Measuring Chiropractic Delivery for Neck Pain Clinical Trial
The purpose of the Manual Cervical Distraction: Measuring Chiropractic Delivery for Neck Pain Clinical Trial is to examine the patient-centered clinical and biomechanical outcomes, doctor treatment delivery, and believability…
- Trial name
- MCD (NCT01765751)
- Testing
- Manual Cervical Distraction
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Palmer College of Chiropractic
Smoking, Smoking Cessation
Tobacco Intervention in Primary Care Treatment Opportunities for Providers
The purpose of this study is to evaluate the use of "sampling" of smoking cessation medications (nicotine patches and lozenges) among smokers seen in primary care settings.
- Trial name
- TipTop (NCT02096029)
- Testing
- Nicotine Replacement Therapy (NRT) Sampling, Ask, Advise, Refer (physician brief advice)
- Where
- United States
- Volunteers
- 1,278 people
- Sponsor
- Medical University of South Carolina
COPD, Self-management Behaviors
Comprehensive Self-management Support for COPD Patients
The study team will adapt and expand an effective model of asthma self-management support for patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- SAMBA COPD (NCT04533412)
- Testing
- Self-management barrier support, Basic COPD Education
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
HIV
Integrated Care Delivery of HIV Prevention and Treatment in AGYW in Zambia
The study team will test a multilevel package of interventions to connect adolescent girls and young women (AGYW) with a source of regular care to provide a sustainable platform for successful implementation of regular human…
- Trial name
- NCT03995953
- Testing
- SHIELD intervention (Support for HIV Integrated Education, Linkages to care, and Destigmatization), Integrated wellness care (IWC) clinics
- Where
- Zambia
- Volunteers
- 2,150 people
- Sponsor
- RTI International
Respiratory Distress Syndrome (RDS)
A Study in Preterm Neonates With Respiratory Distress Syndrome (RDS) Comparing CUROSURF® Administration Through Less Invasive Surfactant Administration (LISA) and Conventional Administration
This study compared the administration of porcine surfactant (poractant alfa, Curosurf®) through a less invasive method (LISA), using a thin catheter, CHF 6440 (LISACATH®), during non-invasive ventilation (CPAP, NIPPV, BiPAP)…
- Trial name
- LISPAP (NCT02772081)
- Testing
- LISA combination product (Curosurf+catheter CHF6440), Curosurf through conventional administration (endotracheal tube)
- Where
- 26 sites in United States
- Volunteers
- 33 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
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