Clinical trials: For Intervention
Suicidal Ideation, Suicide, Attempted
The Group Risk Reduction Intervention Therapy (GRRIT) Project
Investigators will evaluate a group format adaptation of Brief Cognitive-Behavioral Therapy for Suicide (i.e., G-BCBT) on suicide ideation (Aim 1), ability to use coping strategies (Aim 2), and overall mental health (exploratory…
- Conditions
- Suicidal Ideation, Suicide, Attempted, Coping Skills, Depression
- Trial name
- ProjectGRRIT (NCT05401838)
- Testing
- Group Brief Cognitive-Behavioral Therapy (G-BCBT), Dialectical Behavior Therapy (DBT) Skills Group
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- University of North Carolina, Charlotte
Congenital Heart Disease, Congenital Heart Defect
Peer Coaching Intervention in Young Adults With Congenital Heart Disease
The purpose of the study is to evaluate a peer coaching intervention in young adults with congenital heart disease.
- Trial name
- CHASM in ACHD (NCT04271358)
- Testing
- Peer Health Coaching
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Duke University
CT-guided Minimally Invasive Procedures e.g. Biopsies
Evaluation of the XACT Robotic System for Image-guided Percutaneous Lung Procedures
This is a prospective, single arm study, to evaluate the safety, effectiveness and usability of the XACT device. Subjects undergoing CT-guided, minimally invasive percutaneous lung procedures in the interventional radiology…
- Trial name
- NCT04612985
- Testing
- XACT Robotic System
- Where
- 2 sites in United States, Israel
- Sponsor
- Xact Robotics Ltd.
Pain, Acute
Music for Pain in the Waiting Room
This is a single-site, three-arm, parallel-group randomized clinical trial (RCT). The clinical effects of two, 4-minute, audio-recorded, music interventions (one with lyrics and the other without) for orthopedic patients will be…
- Trial name
- NCT06511843
- Testing
- Pain Coping Information, Lyrical Music, Instrumental Music
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Florida State University
Diabetes Mellitus, Type 1
Impact of Dietary Intervention Within an Interprofessional Cooperative Protocol for Prandial Insulin Dose Adjustment in People Living With Type 1 Diabetes
This retrospective multicenter cohort study aims to evaluate the effectiveness of an interprofessional cooperative protocol allowing dietitians to adjust prandial insulin-to-carbohydrate ratios in adults living with type 1…
- Trial name
- INSUDIETCOOP (NCT07846852)
- Testing
- Routine care data collection
- Where
- 2 sites in France
- Volunteers
- 163 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Endometriosis
Nutritional Intervention for Endometriosis
In a 12-week parallel study, women with a verified diagnosis of endometriosis will be randomly assigned to follow a low-fat plant-based diet or to stay on their usual diets for 12 weeks.
- Trial name
- NCT05175248
- Testing
- Plant-based Intervention Group
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Physicians Committee for Responsible Medicine
Pain, Anxiety
Nonpharmacologic Analgesia for Invasive Procedures
Analgesics and sedatives administered to control distress from minimally invasive surgical procedures have limited effectiveness and serious side effects.
- Trial name
- NCT00010855
- Testing
- Self-hypnotic relaxation
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Head and Neck Squamous Cell Carcinoma
Online Sharing for Head & Neck Cancer Support
Head and neck cancer patients often experience significant anxiety and depression during radiation therapy, which can affect their quality of life and treatment adherence.
- Trial name
- NCT07766226
- Testing
- Social Sharing-Based Mobile Application, Usual Care with Psycho-educational Manual
- Where
- China
- Volunteers
- 120 people
- Sponsor
- West China Hospital
Speech Disorders
Table to Tablet (T2T): A Novel Intervention Framework for Children With Speech Sound Disorders
The primary aim of this study is to develop software as a tool in speech and language therapy for the treatment of children (Portuguese and English) with phonologically based Speech Sound Disorders (SSD).
- Trial name
- NCT02490826
- Testing
- Table-based T2T intervention, Tablet-based T2T intervention
- Where
- Portugal
- Volunteers
- 22 people
- Sponsor
- Aveiro University
Phenylketonurias
Development of Novel Psychological Assessment Tools and Anxiety Intervention for Phenylketonuria
While previous PKU intervention research has largely focused on pharmacological treatment of elevated Phe levels, the adaptation of evidence-based psychosocial therapy holds promise for addressing cognitive and psychological…
- Trial name
- NCT06560736
- Testing
- Show Me FIRST coping skills intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Missouri-Columbia
Oppositional Defiant Disorder, Behaviour Disorder
Strongest Families Ontario (Formerly the Family Help Program)
Strongest Families (formerly Family Help)is an evidence-based, distance health education model for families who have children with behavioural difficulties.
- Trial name
- SF-ON (NCT01473511)
- Testing
- Strongest Families Intervention (formerly Family Help)
- Where
- Canada
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
IPV, Perinatal
Strength for U in Relationship Empowerment
The objective of this study is to test whether the innovative intervention, "Strength for U in Relationship Empowerment" (SURE), reduces the frequency of IPV more than an attention, time, and information matched control condition…
- Conditions
- IPV, Perinatal, Mental Health
- Trial name
- SURE (NCT04218864)
- Testing
- Strength for U in Relationship Empowerment (SURE), Attention, time, and information matched control
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Multiple Sclerosis, Pain
Effectiveness of a Mindfulness-Based Intervention for Pain Management in Patients With Multiple Sclerosis (MPIMS).
The goal of this clinical trial is to evaluate whether a mindfulness-based intervention is effective for reducing pain in adults with multiple sclerosis.
- Conditions
- Multiple Sclerosis, Pain, Pain Management
- Trial name
- MPIMS (NCT07741864)
- Testing
- Mindfulness-based intervention, Educational intervention
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Hospital Universitario Virgen Macarena
Chronic Shoulder Pain, Rotator Cuff Related Shoulder Pain
HIIT for Inflammatory-driven Shoulder Pain.
This feasibility study investigates whether high-intensity interval training (HIIT) is feasible and acceptable for individuals with long-term shoulder pain where low-grade inflammation is suspected.
- Conditions
- Chronic Shoulder Pain, Rotator Cuff Related Shoulder Pain, Frozen Shoulder, Shoulder Adhesive Capsulitis
- Trial name
- NCT07275164
- Testing
- High intensity interval training (HIIT)
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Malnutrition
Trial to Test the Growth-Promoting Effect of Fortified Spreads When Used as Complementary Food for Infants
This study tests the hypothesis that infants receiving fortified spread as a complementary food for one year grow better and do not become malnourished as often as infants who are provided with maize-soy flour for complementary…
- Trial name
- NCT00131209
- Testing
- fortified spread (RUTF), maize and soy flour
- Where
- Malawi
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Tampere University
Cognitive Decline, Aging
Effects of Comprehensive Community Support Programs on Cognitive Function and Quality of Life in Older Adults
This prospective observational study aims to investigate the effects of a multidomain community-based support program on cognitive function and quality of life in older adults attending the Vefahane Life Center in Istanbul…
- Conditions
- Cognitive Decline, Aging, Quality of Life
- Trial name
- NCT07610109
- Testing
- Multidomain Community Support Program
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul Medipol University Hospital
Benzodiazepine Dependence, Anxiety Disorders
Anxiety Lowering and Deprescribing Through Emotion Regulation
The goal of this clinical trial is to test ALDER (Anxiety Lowering and Deprescribing through Emotion Regulation), an online self-guided positive emotion intervention, in patients over the age of 65 who are candidates for…
- Conditions
- Benzodiazepine Dependence, Anxiety Disorders, Sleep Disturbance
- Trial name
- ALDER (NCT06359314)
- Testing
- ALDER
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Obesity
Digital Intervention for Behaviour Change and Chronic Disease Prevention
Body weight, diet quality, physical activity, stress, sleep and alcohol use will be evaluated in a sample of 180 Albertans with excess body weight.
- Trial name
- DIRECTION (NCT05579704)
- Testing
- Web-based wellness platform, Healthcare professional-facilitated online support group
- Where
- Canada
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University of Alberta
HIV
Using MOST to Optimize an HIV Care Continuum Intervention for Vulnerable Populations
The present study targets the large population of persons living with HIV/AIDS (PLHA) in the U.S. who are both insufficiently engaged in HIV primary care and not taking antiretroviral therapy (ART), who are mainly African…
- Trial name
- HTH2-MOST (NCT02801747)
- Testing
- Heart to Heart2 (HTH2)
- Where
- United States
- Volunteers
- 512 people
- Sponsor
- New York University
Gambling Problem
Developing and Testing a Brief Intervention for Problem Gambling in Credit Counseling
This study will implement a brief intervention with text messaging and will test its effectiveness in reducing gambling behavior and improving financial well-being among credit counseling clients who seek services.
- Trial name
- NCT04064749
- Testing
- Text messages
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
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