Clinical trials: For Intervention
Intraocular Pressure, Anesthesia
An Observational Study of the Use of Chloral Hydrate for Ophthalmic Procedures in Children
The study involves a prospective evaluation of chloral hydrate sedation for the measurement of intraocular pressure in children ages one month to five years of age.
- Trial name
- NCT02985567
- Testing
- Intraocular pressure evaluation
- Where
- Saudi Arabia
- Volunteers
- 324 people
- Sponsor
- Johns Hopkins University
Temperature Change, Body, Emergency Department Visit
Performance Study of the Thermodiag Solution for Body Temperature Measurement
The goal of this prospective, comparative, multi-centre interventional clinical investigation, is to evaluate the performance of the Thermodiag® medical device, compared with reference methods, for continuous measurement of core…
- Trial name
- ThermodiagPERF (NCT06703931)
- Testing
- Measures performed on all subjects
- Where
- 4 sites in France
- Volunteers
- 60 people
- Sponsor
- F2D Medical
Depression
Psycho-behavioral Intervention for Depression in Chronic Heart Failure
The study aims to explore the effectiveness of psycho-behavioral intervention on depressive symptoms among older adults with chronic heart failure.
- Trial name
- NCT03233451
- Testing
- Psycho-behavioral intervention
- Where
- 6 sites in China
- Volunteers
- 236 people
- Sponsor
- Peking University
Atrial Fibrillation (AF), Ablation Techniques
Electroporation vs. Radiofrequency Ablation Guided by 3D Imaging in Repeat Procedures for Atrial Fibrillation
This is a prospective, randomized clinical trial evaluating the efficacy and safety of two techniques for repeat catheter ablation in patients with recurrent atrial fibrillation (AF): thermal energy ablation (radiofrequency) and…
- Conditions
- Atrial Fibrillation (AF), Ablation Techniques, Radiofrequency Catheter Ablation, Pulsed Field Ablation
- Trial name
- ERA-rePVI (NCT07141745)
- Testing
- Pulsed field ablation of reccurent atrial arrythmia, Radiofrequency ablation of reccurent atrial arrythmia (standard of care)
- Where
- Poland
- Volunteers
- 250 people
- Sponsor
- Wroclaw Medical University
Twin Reversal Arterial Perfusion Syndrome
TRAP Intervention STudy: Early Versus Late Intervention for Twin Reversed Arterial Perfusion Sequence
Multi-center open-label randomized controlled trial to assess if early intervention (12.0-14.0 weeks) (study group) improves the outcome of TRAP sequence as compared to late intervention (16.0-19.0 weeks) (control group).
- Trial name
- TRAPIST (NCT02621645)
- Testing
- Early selective reduction of TRAP mass, Late selective reduction of TRAP mass, Ultrasound-guided intrafetal ablation using a 18 to 20 Gauge needle
- Where
- 14 sites in United States, Austria and 9 more
- Volunteers
- 126 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Hyperthermic Intraperitoneal Chemotherap, Colorectal Cancer Metastatic
Cost-utility Evaluation of Cytoreductive Surgery With or Without Mitomycin-C Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Resectable Colorectal Peritoneal Metastases
Colorectal cancer is the second leading cause of cancer death in France, with close to 50,000 new cases each year. About half of the patients develop liver, lung and/or peritoneal metastases during the course of the…
- Conditions
- Hyperthermic Intraperitoneal Chemotherap, Colorectal Cancer Metastatic, Peritoneal Metastases, Cytoreductive Surgery
- Trial name
- ECO-CHIP (NCT07901075)
- Volunteers
- 398 people
- Sponsor
- Hospices Civils de Lyon
Attention Deficit Hyperactivity Disorder Symptoms
Implementation Strategy Resource Package for Behavioral Classroom Interventions: Pilot Test
The purpose of this study is to pilot test for feasibility and initial promise an implementation strategy resource package that aims to support teachers in using behavioral classroom management interventions for children with…
- Trial name
- NCT05489081
- Testing
- Positive Behavior Management Toolkit
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Temporomandibular Disorders (TMD)
Journaling Intervention for Temporomandibular Disorder (TMD) and Chronic Overlapping Pain
The goal of this clinical trial is to learn whether a 2-week gratitude journaling activity is feasible and acceptable for individuals with Temporomandibular Disorder (TMD) and chronic overlapping pain.
- Trial name
- NCT06977100
- Testing
- Gratitude, General Wellness
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Florida
Depression
Technology-enhanced Therapy: the SilverCloud Study
This pilot study investigates a new platform for supporting online interventions for common mental health problems called SilverCloud.
- Trial name
- NCT01498107
- Testing
- SilverCloud Platform
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Cambridge
Coronary Artery Diseases
BIOFLOW-III VIP Russia Registry Orsiro Stent System
Clinical evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES). Along with it, an explanatory (hypothesis-finding) problem will be investigated, whether the patient's body…
- Trial name
- NCT02247492
- Where
- 7 sites in Russia
- Volunteers
- 200 people
- Sponsor
- Biotronik Russia
Coronary Artery Disease
Technology-Enhanced Continuous Nursing System (TECNS) for Post-CABG Recovery
This is a prospective, randomized controlled trial to evaluate the effectiveness of a Technology-Enhanced Continuous Nursing System (TECNS) compared to routine care for patients after coronary artery bypass grafting (CABG).
- Trial name
- NCT07117331
- Testing
- Technology-Enhanced Continuous Nursing System, Routine Postoperative Care
- Where
- China
- Volunteers
- 358 people
- Sponsor
- The First Hospital of Hebei Medical University
Postprandial Hyperglycemia, Metabolic Disorder, Glucose
Westlake N-of-1 Trials for Macronutrient Intake
This is a dietary intervention study in students and staff of Westlake University, which is designed to provide evidence in support of N-of-1 methods as an approach to advance personalized nutrition.
- Trial name
- WE-MACNUTR (NCT04125602)
- Testing
- High fat low carbohydrate diet, Low fat high carbohydrate diet
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Westlake University
Passive Smoking, Tobacco Smoke Pollution
Educational Models for Tobacco Exposure Awareness
This is a randomized controlled trial comparing the effects of peer education and traditional education on increasing knowledge and awareness of secondhand and thirdhand tobacco smoke exposure among geriatric care program…
- Conditions
- Passive Smoking, Tobacco Smoke Pollution, Health Education, Peer Group Guidance
- Trial name
- NCT07473245
- Testing
- Peer Education, traditional education
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Alzheimer Disease
Nutrition Interventions for Cognitive Enhancement
By doing this study, researchers hope to learn how the Mediterranean and low-fat eating patterns affect memory, brain volume, brain antioxidant status and cardio-metabolic biomarkers, such as blood pressure and blood glucose, in…
- Trial name
- NICE (NCT03841539)
- Testing
- Mediterranean Diet, Study Supplement, Low-fat Diet
- Where
- United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Depression
A Randomised Controlled Trial of Home-based Exercise Intervention for Caregivers of Persons With Dementia
The study aims to compare the efficacy of a home-based structured exercise programme (12-step sitting Tai Chi) involving both persons with dementia and their caregivers with a standard non-exercise social contact control in…
- Trial name
- NCT02132039
- Testing
- 12-step sitting Tai Chi Chuan, Control
- Where
- 5 sites in China
- Volunteers
- 272 people
- Sponsor
- The University of Hong Kong
Orthopedic Procedure, Anesthesia
Evaluation of the Impact of Virtual Reality on Sedation Use in Patients Undergoing Regional Anesthesia for Scheduled Orthopedic Surgery
The VIRTUALR study evaluates the effect of virtual reality combined with hypnosis on anxiety in patients undergoing orthopedic surgery under regional anesthesia.
- Conditions
- Orthopedic Procedure, Anesthesia, Sedation
- Trial name
- VIRTUALR (NCT07013695)
- Testing
- Virtual reality headset, Standard Care (in control arm)
- Where
- France
- Volunteers
- 164 people
- Sponsor
- Centre Hospitalier Eure-Seine
COPD (Chronic Obstructive Pulmonary Disease)
Development And Evaluation of An Adaptive Web-Based Intervention for COPD
Narrative-based tiered asynchronous psychosocial and behavioral whole health support for people adjusting to living with COPD. The intervention is administered by experienced LCSWs under the PI's supervision.
- Trial name
- NCT06770777
- Testing
- Tiered whole health support for people living with COPD
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Breast Reconstruction, Venous Thromboembolism
Microsurgical Breast Reconstruction & VTE
Venous thromboembolism (VTE) encompasses pulmonary embolism (PE) and deep venous thrombosis (DVT) and continues to be a major patient safety issue after reconstructive plastic surgery.
- Trial name
- NCT03031457
- Testing
- Duplex ultrasound
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Gestational Diabetes Mellitus in Pregnancy
Lifestyle Intervention for Prevention of Gestational Diabetes Mellitus in the UAE Population
Gestational diabetes mellitus (GDM) is a high blood glucose (hyperglycemia) first occurring or first recognized during pregnancy, it is affecting 16.4% of women globally and 36.6 % in this region.
- Trial name
- NCT04273412
- Testing
- moderate-intensity lifestyle intervention
- Where
- United Arab Emirates
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Rashid Centre for Diabetes and Research
Breast Carcinoma
A Digital Health Intervention to Improve Symptoms and Physical Activity During Breast Radiation
This clinical trial evaluates a digital health intervention for improving symptoms and physical activity among patients with breast cancer undergoing radiation.
- Trial name
- PRO-ACTIVE (NCT06772181)
- Testing
- IM@Home Program, Medical Device Usage and Evaluation, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Washington
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