Clinical trials: For Intervention, active
Small-cell Lung Cancer, Extensive-stage Small-cell Lung Cancer
Durvalumab in Combination With Standard Chemotherapy of Patients With Extensive Stage Small Cell Lung Cancer
This is a non-interventional, multicenter, prospective observational study and registry of standard clinical practice in patients with Extensive Stage-Small Cell Lung Cancer (ES-SCLC) receiving 1st line treatment with Durvalumab…
- Trial name
- DRIVE (NCT05761977)
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Hellenic Cooperative Oncology Group
Postoperative Care
Rocking Chairs as Post-operative Treatment for Older Adults After Hip Surgery
Feasibility and acceptability randomized controlled trial exploring the use of a rocking chair after a total hip arthroplasty in adults who are aged 65 or older.
- Trial name
- FAIRChair (NCT07544550)
- Testing
- Active rocking in a rocking chair, Sitting upright in a stationary chair
- Volunteers
- 60 people
- Sponsor
- University of Missouri, Kansas City
Schizophrenia and Related Disorders
Tele-group Cognitive Behavioural Family Intervention for Individuals With Schizophrenia and Their Families (Definitive tgCBFI)
This mixed-method study comprises a RCT with a twelve-week post-intervention follow-up and focus group interviews. The RCT study aims to examine the effectiveness of delivering the tgCBFI programme to dyads of people with…
- Trial name
- NCT07121166
- Testing
- tgCBFI programme, Treatment as Usual (TAU)
- Where
- 6 sites in Hong Kong
- Volunteers
- 200 people
- Sponsor
- The Hong Kong Polytechnic University
Acute Heart Failure (AHF), Congestive Heart Failure Acute
POcus INTERvention for Tailoring Diuretic Strategy in Acute Decompensated Heart Failure
Acute decompensated heart failure (ADHF) is a frequent cause of hospitalization and is associated with high morbidity and mortality.
- Conditions
- Acute Heart Failure (AHF), Congestive Heart Failure Acute, Diuretic Effect, Lung Ultrasonography Score
- Trial name
- POINTER-HF (NCT07469722)
- Testing
- Furosemide 40 Milligrams., Hydrochlorothiazide (HCTZ) 25 milligrams., Acetazolamide 250 milligrams.
- Where
- Brazil
- Volunteers
- 128 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Family Conflict, Relationship, Parent Child
Nonviolent Communication Plus Personalised E-message for Parents
This pilot randomised controlled trial (RCT) aims to evaluate the feasibility, acceptability, and preliminary effects of combining a brief Nonviolent Communication (NVC) intervention with follow-up personalised AI-generated…
- Trial name
- NCT07826702
- Testing
- Healthy Lifestyle Tips, Nonviolent Communication Intervention & Personalised E-messages
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Hong Kong Metropolitan University
Schizophrenia Disorders, Personality Disorders
Recovery in Telling Life Stories
This project tests the Recovery In Telling Life Stories (RETELL) intervention, aimed at supporting personal recovery in people with severe mental illness (SMI).
- Conditions
- Schizophrenia Disorders, Personality Disorders, Obsessive - Compulsive Disorder, Anxiety Disorders
- Trial name
- RETELL (NCT07082777)
- Testing
- Narrative therapy
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Telementoring Intervention (ECHO) for the Transformation of Professional Engagement, Practice Efficiency, and Community Building Through Team Meetings in Diagnostic Imaging Clinicians
This trial studies how well the Extension for Community Healthcare Outcomes (ECHO) telementoring intervention works in transforming professional engagement, practice efficiency, and community building through team meetings in…
- Trial name
- NCT04196972
- Testing
- Communication Intervention, Questionnaire Administration, Waiting List
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Test Anxiety
Internet-Based EMDR Flash Intervention for Test Anxiety in University Students
The aim of this study is to investigate whether an Internet-based EMDR Flash intervention can help reduce exam anxiety among university students.
- Trial name
- NCT07154329
- Testing
- Internet-Based EMDR-Flash Program
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Tokat Gaziosmanpasa University
Acute Kidney Injury in the ICU
Automated System for Monitoring Urine Output in Intensive Care Patients
Acute kidney injury is common among ICU-admitted patients, and is associated with increased morbidity and mortality. Early recognition is essential to prevent complications.
- Trial name
- NCT05232045
- Testing
- Automated urinary output collection system group (tight monitoring of urine output)
- Where
- Israel
- Volunteers
- 1,800 people
- Sponsor
- Meir Medical Center
Crohn's Disease
An Observational Study to Assess Change in Disease Activity and Adverse Events in Adolescent and Adult Participants With Moderate to Severe Active Crohn's Disease (CD) in Japan
Crohn's disease (CD) is an incurable chronic inflammatory disorder of the gastrointestinal tract. This study will assess how safe and effective upadacitinib is in treating moderately to severely active CD in real world.
- Trial name
- NCT06023030
- Where
- 104 sites in Japan
- Volunteers
- 240 people
- Sponsor
- AbbVie
B-Cell Non-Hodgkin Lymphoma (NHL)
Non-Interventional Study of Ranicabtagene Autoleucel Injection for Relapsed/Refractory B-cell Non-Hodgkin Lymphoma
Establishing real-world data of patients with relapsed/refractory B-cell non-Hodgkin lymphoma (r/r B-NHL) treated with Ranicabtagene Autoleucel Injection to evaluate its efficacy and safety.
- Trial name
- NCT07888530
- Testing
- Ranicabtagene Autoleucel Injection
- Volunteers
- 200 people
- Sponsor
- Hrain Biotechnology Co., Ltd.
Chronic Heart Failure
Nurse-Led Education for Heart Failure Self-Care and Stability
Heart failure is a chronic condition that can lead to frequent hospitalizations and reduced quality of life. This study aims to evaluate whether a nurse-led, face-to-face educational intervention can improve clinical stability…
- Trial name
- EDUCATE (NCT07280728)
- Testing
- Nurse-Led Face-to-Face Educational Intervention (Teach-Back Method)
- Where
- Italy
- Volunteers
- 118 people
- Sponsor
- Azienda Socio Sanitaria Territoriale di Lodi
Trauma and Stressor Related Disorders, Pediatric Cancer
Emotion and Symptom-Focused Engagement (EASE) for Caregivers
The goal of this Phase III randomized controlled trial is to evaluate the effectiveness of a novel psychotherapeutic intervention called Emotion and Symptom-focused Engagement (EASE) in parents caring for a child or adolescent…
- Conditions
- Trauma and Stressor Related Disorders, Pediatric Cancer, Caregiver Burden
- Trial name
- EASE (NCT06367556)
- Testing
- Emotion and Symptom-Focused Engagement (EASE)
- Where
- 2 sites in Canada
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Edentulism Complete, Denture, Complete
Nutritional Intervention for Older Adults With Complete Dentures
The purpose of this clinical trial is to test a nutritional intervention. This study helps older adults who wear complete removable dentures improve their health.
- Conditions
- Edentulism Complete, Denture, Complete, Mastication Disorder
- Trial name
- NCT07692828
- Testing
- Nutritional Intervention
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- Universidad de La Frontera
Unipolar Depression
Bright Light Therapy for Depressed Geriatric Inpatients
Bright light therapy has been shown to be effective for the treatment of both seasonal and non-seasonal unipolar depression as well as bipolar depression, primarily in outpatients under the age of 60.
- Trial name
- NCT07002554
- Testing
- Bright light therapy, dim red light
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Major Depressive Disorder, Substance Use Disorders
Peer-Delivered Behavioral Activation in a CCBHC
Low-income individuals have limited access to evidence-based interventions for mental health. Peer recovery specialists, individuals in recovery from mental health and/or substance use problems, have the potential to increase…
- Trial name
- NCT07219394
- Testing
- Peer Activate, Peer-delivered non-specific services
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Wayne State University
Major Depression
Modular Intervention for Depression Study
The goal of this psychotherapy clinical trial is to evaluate whether a algorithm-based personalized modular psychotherapy is more effective than usual individual psychotherapy in treating major depressive disorder complicated by…
- Trial name
- MIND (NCT07380451)
- Testing
- Modular Intervention for Depression Therapy (MIND Therapy), Psychotherapy as Usual (TAU)
- Where
- 5 sites in Chile
- Volunteers
- 150 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Growth Hormone Deficiency in Children, Born Small for Gestational Age
Influence of Adherence to Growth Hormone Therapy (GHT) With Norditropin® on Near Final Height in Patients With Growth Hormone Deficiency (GHD) and Born Small for Gestational Age (SGA)
Participants are free to decide if they want to take part in this study or not. The study will be conducted to collect information about the influence of adherence to growth hormone therapy with Norditropin® in children and…
- Trial name
- NCT03972345
- Testing
- Norditropin® FlexPro®
- Where
- Germany
- Volunteers
- 750 people
- Sponsor
- Novo Nordisk A/S
Malnutrition, Cancer-related Malnutrition
Nutritional Prehabilitation to Improve Cancer Outcomes (N-PICO)
Brief Summary The goal of this clinical trial is to evaluate the acceptability and adherence of low- and high-intensity remote nutritional interventions for cancer patients in rural and urban areas, specifically focusing on those…
- Conditions
- Malnutrition, Cancer-related Malnutrition, Quality of Life (QOL), Nutritional Support
- Trial name
- N-PICO (NCT07072377)
- Testing
- Intensity of Nutritional Intervention, Remote or In-Person
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of Vermont Medical Center
Diabetes
EFFECTIVENESS OF A TRIPLE NUTRITIONAL INTERVENTION AND PHYSICAL IN PREDIABETIC PATIENRS
Diabetes represents a substantial burden on health care systems. People with prediabetes IGT (impaired glucose tolerance) or IFG (impaired fasting glucose) are at high risk of developing diabetes, and up to 50% progress to…
- Trial name
- NCT06820775
- Testing
- A TRIPLE INTERVENTION NUTRITION AND PHYSICAL ACTIVITY
- Where
- Spain
- Volunteers
- 82 people
- Sponsor
- Bioaraba Health Research Institute
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