Clinical trials: For Oncologic Patients
Lymphoma, Diabetes Mellitus, Type 2
Validation of Insulin Protocol for Glucocorticoid-induced Hyperglycemia in Diabetic Oncology Patients
There are no guidelines for the management of glucocorticoid- (henceforth steroid) induced elevated blood sugars (henceforth hyperglycemia).
- Conditions
- Lymphoma, Diabetes Mellitus, Type 2, Hyperglycemia
- Trial name
- NCT02012465
- Testing
- Insulin protocol
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Washington University School of Medicine
Head and Neck Cancer
Couple-Based Intervention for Patients With Head and Neck Cancer and Their Partners
The purpose of this study is to determine whether a brief couple-based supportive intervention effectively assists patients and their partners coping with the challenges of head and neck cancer.
- Trial name
- CoupleCare (NCT01785576)
- Testing
- Couple-Based CBT Intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Endeavor Health
Cancer
The ICT Based Prescription of Physical Activity for Oncology Patients at Their Home
Study evaluating the efficacy of ICT-based prescription of physical activity in oncology patients
- Trial name
- EASYDOM (NCT07021196)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Federico II University
Multiple Myeloma, Solitary Plasmacytoma
MargheRITA (Remote Intelligence for Therapeutic Adherence)
It is essential to improve clinical efficiency and management of hematological and oncological patients treated on an outpatient basis.
- Conditions
- Multiple Myeloma, Solitary Plasmacytoma, Amyloidosis, Chronic Myeloid Leukemia
- Trial name
- MargheRITA (NCT05260203)
- Testing
- RITA (App)
- Where
- Italy
- Volunteers
- 124 people
- Sponsor
- Advice Pharma Group srl
Carcinoma, Transitional Cell (RENI)
Prognostic Value of Performance Scores in Patients Undergoing Surgery for Upper Tract Urothelial Carcinoma
Aim: to comprehensively evaluate the prognostic value of preoperative ECOG-PS scores and ASA scores in patients undergoing radical nephroureterectomy (RNU) for upper tract urothelial carcinoma. Methods: multicentered cohort study
- Trial name
- NCT06305130
- Testing
- No intervention
- Volunteers
- 2,515 people
- Sponsor
- Kaohsiung Medical University
Advanced Malignant Female Reproductive System Neoplasm
An Artificial Intelligence Algorithm for Identifying Gynecologic Cancer Patients in Need of Outpatient Palliative Care
This clinical trial tests an artificial intelligence (AI) algorithm for its ability to identify patients who may benefit from a palliative care consult for gynecologic cancer that has spread from where it first started to nearby…
- Trial name
- NCT06182332
- Testing
- Electronic Health Record Review, Internet-Based Intervention
- Where
- United States
- Volunteers
- 221 people
- Sponsor
- Mayo Clinic
Cancer, Oncology
Intelligent Electric Bicycle for Health (VELIS) to Optimize the Return to Physical Activity for Oncology Patients
The purpose of this pilot study is to encourage oncology patients to continue effort retraining after their release from rehabilitation and recuperative care facilities with physical activity sessions and therapeutic education…
- Trial name
- NCT03340857
- Testing
- Intelligent electric bicycle (VELIS) sessions
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Fondation Audavie
Hematologic Neoplasms, Oncologic Disorders
LLM-Generated Plain-Language Patient Synopses to Improve Comprehension in Hematology and Oncology (oncOPAL)
This study tests whether patients with blood cancer or other cancers better understand their medical information when it is rewritten in plain language by an artificial intelligence (AI) system.
- Trial name
- oncOPAL (NCT07519811)
- Testing
- LLM-Generated Plain-Language Patient Synopsis
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Technical University of Munich
NSCLC (Advanced Non-small Cell Lung Cancer), NSCLC Stage IIIB~IV
Immune-Marker Platform for Patients With Advanced Lung Cancer
The goal of this observational study is to better understand how the immune system and certain tumor markers are linked to treatment response in patients with advanced non-small cell lung cancer (NSCLC) who receive…
- Conditions
- NSCLC (Advanced Non-small Cell Lung Cancer), NSCLC Stage IIIB~IV, NSCLC Non-small Cell Lung Cancer
- Trial name
- IMPALUX (NCT07150598)
- Where
- 2 sites in Germany
- Volunteers
- 500 people
- Sponsor
- Technische Universität Dresden
Adenocarcinoma of the Pancreas, Advanced Solid Tumors
QUILT-2.014: Gemcitabine and AMG 479 in Metastatic Adenocarcinoma of the Pancreas
AMG 479 is an investigational fully human monoclonal antibody that targets type 1 insulin-like growth factor receptor (IGF-1R). Signaling through IGF-1R plays an important role in the regulation of cell growth and survival.
- Conditions
- Adenocarcinoma of the Pancreas, Advanced Solid Tumors, Cancer, Cancer of Pancreas
- Trial name
- GAMMA (NCT01231347)
- Testing
- AMG 479, gemcitabine
- Where
- 152 sites in United States, Australia and 30 more
- Volunteers
- 800 people
- Sponsor
- NantCell, Inc.
Breast Cancer Metastatic
E-Health Portal for Individualized Treatment Monitoring and Patient Engagement in Oncology Research
Evaluation of patient acceptance and characterization of response behaviour for web-based compared with respective paperbacked patient reported outcomes.
- Trial name
- NCT03132506
- Testing
- patient-reported-outcomes
- Where
- Germany
- Volunteers
- 106 people
- Sponsor
- University Hospital Tuebingen
Multiple Myeloma, Multiple Myeloma Without Mention of Remission
Evaluating the Uptake and Utility of Clinical Pathways for Newly Diagnosed Patients With Multiple Myeloma
All4Cure is partnering with community oncology practices participating in the Quality Cancer Care Alliance (QCCA) and Exigent Research to develop a clinical pathway that standardizes the evaluation, treatment and ongoing…
- Trial name
- NCT06149910
- Testing
- Multiple Myeloma Pathway, All4Cure Platform, Documentation Pathway
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- All4Cure
Adenocarcinoma, Gastric, Neoplasm, Breast
DS-8201a in Patients With Cancer That Tests Positive for Human Epidermal Growth Factor Receptor 2 (HER2) Protein
HER2-positive cancer is a cancer that tests positive for a protein called human epidermal growth factor receptor 2 (HER2). HER2 promotes the growth of certain cancer cells.
- Trial name
- NCT03368196
- Testing
- DS-8201a
- Where
- 2 sites in Taiwan
- Volunteers
- 12 people
- Sponsor
- Daiichi Sankyo Taiwan Ltd., a Daiichi Sankyo Company
Pediatric Cancer
Cross-cultural Adaptation and Validation of the P-CIN for Chinese Pediatric Oncology Patients
The goal of this study was to conduct a cross-cultural adaptation of the P-CIN into the Chinese context, assess its psychometric properties, and determine the cut-off value of CIPN among Chinese pediatric oncology patients.
- Trial name
- NCT07053579
- Where
- 2 sites in Hong Kong
- Volunteers
- 313 people
- Sponsor
- The Hong Kong Polytechnic University
Radiotherapy Side Effect
SMC Radiation Oncology Breast Cancer Cohort Study
The goal of this observational study is to learn about toxicities and cosmetic outcomes in breast cancer patients treated with hypofractionated radiotherapy.
- Trial name
- RASCO (NCT05775757)
- Testing
- Hypofractionated radiation therapy
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Samsung Medical Center
Oncology
Prophylactic Oral Vitamin D and Zinc for Radiation-Induced Oral Mucositis in Head and Neck Cancer
The main aim of this study was to evaluate clinically the effect of a combination between oral vitamin D and oral zinc in comparison to conventional therapy in prevention of radiotherapy-induced oral mucositis in Assiut…
- Trial name
- NCT06100692
- Testing
- Vitamin D
- Volunteers
- 100 people
- Sponsor
- Assiut University
Cancer
Deployment of Teleconsulting in Geriatric Oncology for Older Patients
Cancer affects mostly older adults. The development of Geriatric Oncology has greatly improved the management of older patients with the Comprehensive Geriatric Assessments (CGA) being conducted before cancer treatment.
- Trial name
- TeleOncoGe (NCT05619731)
- Testing
- Geriatric oncology tele-consultation and pharmaceutical tele-expertise
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Myelodysplastic Syndrome
An Effectiveness and Safety Study of Decitabine in Patients With Myelodysplastic Syndrome
The purpose of this study is to evaluate the effectiveness and safety of decitabine in the treatment of myelodysplastic syndrome (name of a group of conditions that occur when the blood-forming cells in the bone marrow are…
- Trial name
- NCT01751867
- Testing
- Decitabine at 15 mg/m2, Decitabine at 20 mg/m2
- Where
- 8 sites in China
- Volunteers
- 135 people
- Sponsor
- Xian-Janssen Pharmaceutical Ltd.
Radiation Dermatitis Acute, Radiation Dermatitis
Oral or Topical Catechins for Radiation Dermatitis
Introduction Radiation-induced dermatitis (RID), which includes both acute and chronic forms, affects up to 95% of patients undergoing radiation therapy.
- Conditions
- Radiation Dermatitis Acute, Radiation Dermatitis, Fibrosis; Skin
- Trial name
- OCTOPUS-RD (NCT07149506)
- Testing
- Epicatechin, Epigallocatechin Gallate (EGCG), Saline (0.9% NaCl)
- Where
- Mexico
- Volunteers
- 162 people
- Sponsor
- CARLOS FRANCISCO SAAVEDRA GARCIA
Peritoneal (Metastatic) Cancer, Peritoneal Carcinoma
Paricalcitol Versus Pirfenidone for Improving Surgical Resectability in Patients With Peritoneal Cancer
The goal of this clinical trial is to learn if paricalcitol or pirfenidone can help make tumors removable by surgery in adults with peritoneal cancer who are currently unable to have their tumor removed.
- Conditions
- Peritoneal (Metastatic) Cancer, Peritoneal Carcinoma, Peritoneal Carcinosis, Peritoneal Cancer
- Trial name
- RANDY 1A (NCT07856914)
- Testing
- Paricalcitol, pirfenidone
- Volunteers
- 74 people
- Sponsor
- Patrick Wagner, MD, FACS