Clinical trials: For Oncologic Patients
Pancreatic Ductal Adenocarcinoma
NGS and TME for Evidence-based Treatment of Pancreatic Cancer
The tumor tissue of patients with pancreatic cancer will be submitted to next-generation sequencing (NGS) and these data will be evaluated with an oncology treatment decision support (TDS) software tool that is a medicinal…
- Trial name
- PePaCaKa-01 (NCT02767700)
- Testing
- NGS
- Volunteers
- 39 people
- Sponsor
- Karolinska University Hospital
Oral Mucositis Due to Chemotherapy, Hematolymphoid Malignancies
Phase II Single Arm Open Label Study Evaluating the Feasibility and Safety of Photobiomodulation as an Adjunct to Standard Supportive Care for Chemotherapy Induced Oral Mucositis in Pediatric Patients With Hematolymphoid Malignancies
Chemotherapy induced oral mucositis is a common and debilitating complication in pediatric patients receiving chemotherapy for hematolymphoid malignancies.
- Trial name
- BEAM (NCT07605234)
- Testing
- Photobiomodulation Therapy
- Volunteers
- 46 people
- Sponsor
- Tata Memorial Hospital
Renal Cancer, Renal Neoplasm
Laparoscopic Partial Nephrectomy for cT1 Tumors
The aim of the study is to evaluate trifecta and pentafecta outcomes for laparoscopic partial nephrectomy (LNP) in patients with clinical T1N0M0 renal tumor.
- Conditions
- Renal Cancer, Renal Neoplasm, Renal Cell Carcinoma, Surgery
- Trial name
- NCT04213157
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 292 people
- Sponsor
- Samsun Liv Hospital
Acute Myeloid Leukemia
A Collaborative Palliative and Oncology Care Model for Patients With Acute Myeloid Leukemia
This research study is evaluating the impact a collaborative palliative care and oncology team will have on the quality of life, symptoms, mood, and end of life outcomes of patients with acute myeloid leukemia (AML).
- Trial name
- NCT02975869
- Testing
- Standard Leukemia Care, Palliative Care
- Where
- 4 sites in United States
- Volunteers
- 160 people
- Sponsor
- Massachusetts General Hospital
Advanced Head and Neck Squamous Cell Carcinoma, Advanced Breast Cancer
A Study to Evaluate the Safety and Efficacy of CyPep-1 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic Cancers
This Phase 1b/2a study will assess the efficacy, safety, and pharmacodynamics of CyPep-1 when administered directly into measurable tumor lesions in combination with the anti-PD-1 antibody pembrolizumab.
- Conditions
- Advanced Head and Neck Squamous Cell Carcinoma, Advanced Breast Cancer, Advanced Melanoma
- Trial name
- Catalyst (NCT05383170)
- Testing
- CyPep-1, Pembrolizumab 25 MG/ML [KEYTRUDA®]
- Where
- 25 sites in United States, France and 3 more
- Volunteers
- 6 people
- Sponsor
- Cytovation AS
Liver Cancer, Liver Metastases
DRAGON Registry - International Multicenter Registry and Medical Image Bank for Patients With Primarily Unresectable Liver Cancer or Liver Metastases That Underwent Combined Portal and Hepatic Vein Embolization (PVE/HVE) to Increase Future Liver Remnant Before Resection.
The DRAGON registry aims to collect data on combined portal and hepatic vein embolization (PVE/HVE) for liver tumors, a technique expected to enhance liver regeneration compared to standard PVE.
- Trial name
- NCT07717437
- Where
- 31 sites in United States, Australia and 11 more
- Volunteers
- 350 people
- Sponsor
- Maastricht University Medical Center
Radiodermatitis; Acute, Radiation Dermatitis
Novel Skin Care Product for the Management of Acute Radiodermatitis
Notwithstanding the continuous progress in cancer treatment, patients with cancer still have to cope with quality of life (QoL) - impairing complications.
- Trial name
- RTSkin (NCT04929808)
- Testing
- Hydrating emollient for acute radiodermatitis, Standard institutional skin care
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Jessa Hospital
Cancer, Emergencies
Pro-active Monitoring of Vital Signs in Oncology Patients Using a Smartwatch
The goal of this single center prospective observational study is to determine the effect of chemotherapy on (the change in) vital parameters.
- Trial name
- PROGRESS (NCT06680778)
- Testing
- Proactive Monitoring
- Where
- Netherlands
- Volunteers
- 175 people
- Sponsor
- Erasmus Medical Center
Neoplasms, Frailty
Ready for Safe Cancer Treatment (RESET): A Comprehensive Perioperative Program for Surgical Oncology
The goal of this randomized controlled clinical trial is to evaluate whether the Ready for Safe Cancer Treatment (RESET) program improves perioperative care and supports safe hospital discharge in two surgical populations: adult…
- Conditions
- Neoplasms, Frailty, Surgical Procedures, Operative
- Trial name
- RESET (NCT07727876)
- Testing
- RESET multimodal perioperative care pathway, Standard perioperative care
- Where
- 2 sites in Poland
- Volunteers
- 12,800 people
- Sponsor
- Regional Specialist Hospital in Wroclaw
Pain, Psychosocial Effects of Cancer and Its Treatment
Reflexology or Aromatherapy Massage in Relieving Symptoms in Patients With Cancer
RATIONALE: Reflexology and aromatherapy massage may lessen symptoms in patients with cancer. It is not yet known whether reflexology is more effective than aromatherapy massage in relieving symptoms in patients with cancer.
- Conditions
- Pain, Psychosocial Effects of Cancer and Its Treatment, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT01217424
- Testing
- questionnaire administration, aromatherapy and essential oils, management of therapy complications
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Cutaneous Squamous Cell Carcinoma, Basal Cell Carcinoma
IFx-Hu2.0 for the Treatment of Patients With Skin Cancer
One hundred patients will receive IFx-Hu2.0 on an outpatient basis at a single time point in a single lesion. These patients will be assessed for any immediate adverse reactions and at Week 4 (Day 28+/-5 days) for any delayed…
- Trial name
- NCT04925713
- Testing
- IFx-Hu2.0
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- TuHURA Biosciences, Inc.
Cancer
The ICT Based Prescription of Physical Activity for Oncology Patients at Their Home
Study evaluating the efficacy of ICT-based prescription of physical activity in oncology patients
- Trial name
- EASYDOM (NCT07021196)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Federico II University
Cancer Debulking, Enlarged Uterus
Comparing Intrathecal Morphine and Intraoperative Lidocaine Infusion to Epidural Anesthesia With Postoperative PCA for Patients Undergoing Exploratory Laparotomy
To determine if opioid consumption postoperatively among patients undergoing non-emergent laparotomy by the gynecologic oncology service who receive intrathecal morphine with intraoperative lidocaine (IML) infusion are lower than…
- Conditions
- Cancer Debulking, Enlarged Uterus, Fibroid Uterus, Adnexal Mass
- Trial name
- NCT05017246
- Testing
- Bupivacaine, Morphine, Lidocaine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Washington University School of Medicine
Gynecologic Cancer, Post-operative Pain
Transversus Abdominis Plane Blocks for Patients Undergoing Robotic Gynecologic Oncology Surgery
This study is a single-center, randomized, placebo-controlled, double-blind clinical trial. The purpose of this study is to evaluate the impact of pre-operative transverses abdominis plane (TAP) blocks on post-operative analgesia…
- Trial name
- NCT01444924
- Testing
- Bupivicaine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Wisconsin, Madison
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Reflects the Intervention (AI Chatbot)
The goal of this clinical trial is to investigate the impact of an AI-powered chatbot intervention on improving knowledge, attitudes, and empowerment in breast cancer patients.
- Trial name
- BC-CHAT (NCT06943911)
- Testing
- AI Chatbot for Breast Cancer Patient Education and Empowerment
- Where
- Egypt
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Mostafa Shaban
Psychosocial Effects of Cancer and Its Treatment, Unspecified Adult Solid Tumor, Protocol Specific
Radiation Therapy Outreach Program for Minority or Low-Income Patients With Newly Diagnosed Cancer
RATIONALE: An outreach program may help minority or low-income cancer patients overcome problems that keep them from receiving quality care.
- Trial name
- NCT00400699
- Testing
- counseling intervention, study of socioeconomic and demographic variables, psychosocial assessment and care
- Where
- 4 sites in United States
- Volunteers
- 3,150 people
- Sponsor
- University of Pittsburgh
Gastro-intestinal Cancer, Lung Cancer
The Impact of a Patient Education Intervention for Ambulatory Oncology Patients
This study will test the impact of newly created and available symptom management patient education brochures on symptom burden [measured via the Edmonton Symptom Assessment System (ESAS)], health-related quality of life…
- Conditions
- Gastro-intestinal Cancer, Lung Cancer, Head and Neck Cancer, Breast Cancer
- Trial name
- NCT02038114
- Testing
- Instructed to read patient education pamphlets
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- Sunnybrook Health Sciences Centre
Oncology
Remote COVID-19 Symptom Tracking for Cancer Patients at Home During the Pandemic
This project will evaluate the benefit of an automated home symptom monitoring system, Symptom Care at Home, to track COVID-19 symptoms, provide instructions to reduce COVID-19 exposure, and reduce cancer symptom severity during…
- Trial name
- NCT04464486
- Testing
- SCH Intervention
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- University of Utah
Cancer
Implementation of Shared Decision-Making in Cancer Care
This study aims to evaluate a theoretically and empirically grounded implementation program designed to foster shared decision-making in routine cancer care. The intervention program consists of several components (e.g.
- Trial name
- PREPARED (NCT03393351)
- Testing
- Shared decision-making program, Usual Care
- Where
- 3 sites in Germany
- Volunteers
- 2,131 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Cancer, Nutrition Disorders
Co-designed Nutritional Training Program for Oncology Nurses in Vietnam
This study evaluates a co-designed nutritional training program for oncology nurses in Vietnam. The aim is to improve nurses' knowledge, confidence, and clinical practice in providing nutritional support for patients with cancer…
- Conditions
- Cancer, Nutrition Disorders, Chemotherapy-Related Symptoms
- Trial name
- NUTRI-NURSE-VN (NCT07566169)
- Testing
- Co-Designed Nutritional Training Program
- Where
- Vietnam
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- VinUniversity