Clinical trials: Former Smoker
HIV Infections, Smoking
Improving the Reach & Effectiveness of Smoking Cessation Services Targeted to Veterans Living With HIV
This project will compare the effectiveness of an HIV-specific comprehensive wellness intervention designed to have broad appeal to smokers living with HIV to the effectiveness of standard care services that include referral to…
- Conditions
- HIV Infections, Smoking, Smoking Cessation
- Trial name
- WISH (NCT04505371)
- Testing
- Wellness Intervention for Smokers with HIV
- Where
- United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Respiratory Disorders
A Study to Test if a Third Dose of the Vaccine is Safe in Current and Former Smokers Aged 40 to 80 Years Old and to Gather Information on the Immune Response Following the Third Dose of the Vaccine
The purpose of this study is to test two different vaccine schedules to be used for administering the investigational NTHi Mcat vaccine that will be targeting patients with chronic obstructive pulmonary disease (COPD) to prevent…
- Trial name
- NCT03443427
- Testing
- NTHi Mcat investigational vaccine (GSK3277511A)
- Where
- 8 sites in Canada, Germany and 1 more
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Smoking Cessation
To Explore the Factors Affecting the Effectiveness of Smoking Cessation
Objectives: Promoting quitting smoking and training smoking cessation educators in hospital, school, community, and workplace was being vigorously pushed by Health Promotion Administration.
- Trial name
- NCT03474783
- Testing
- Health education
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Cathay General Hospital
Cessation, Smoking
Effectiveness of an Intervention in Primary Care to Promote Smoking Cessation in Pregnant Women
The purpose of this study is to evaluate the effectiveness of the behavior treatment accompanied by self-help materials in Primary health care, across the intervention of the midwifes in the pregnancy follow-up visits.
- Trial name
- GESTABAC (NCT01872156)
- Testing
- Intervention GESTABAC, Control Group
- Where
- Spain
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Gerencia de Atención Primaria, Madrid
COPD, Asthma
Biomarker Assay Validation in Healthy Smokers and COPD Smokers and Ex-smokers
This study will collect sputum samples from healthy smokers, COPD smokers and COPD ex-smokers to analyse biomarkers of inflammation
- Trial name
- NCT02490358
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Respivert Ltd
Periodontitis
Effect of Smoking Cessation on Clinical and Microbiological Outcomes of the Non-surgical Periodontal Therapy
The aim of this prospective interventional study is to verify the efficacy of smoking cessation on clinical and microbiological outcomes of non-surgical periodontal therapy of chronic periodontitis patients.
- Trial name
- EsCAPE2 (NCT02744417)
- Testing
- Smoking cessation counseling, Non-surgical periodontal therapy, Nicotine replacement therapy
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Claudio Mendes Pannuti
Smoking Cessation
Study on the Model of Smoking Cessation Intervention and Service Ability Improvement
This is a observation non-randomized control trial, and a follow-up study on the smoking cessation.
- Trial name
- NCT01935505
- Testing
- Consulting, Nicotine patch, Telephone intervention
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Former Smoker, Non-Smoker
Vaped Phenanthrene
Some people who used to smoke cigarettes continue to be at higher risk of developing lung cancer, even years after quitting. This study will look to see if a specific chemical, phenanthrene, is broken down in the lungs of former…
- Trial name
- NCT07134426
- Testing
- D10-phenanthrene
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Bronchial Epithelial Dysplasia, Chronic Obstructive Pulmonary Disease
Oral Iloprost for the Prevention of Lung Cancer In Former Smokers
This phase II trial tests whether oral iloprost works in preventing lung cancer (chemoprevention) in former smokers. Oral iloprost has previously been shown to reduce abnormal lung cells in former smokers, suggesting a clinically…
- Conditions
- Bronchial Epithelial Dysplasia, Chronic Obstructive Pulmonary Disease, Lung Carcinoma, Stage I Lung Cancer AJCC v8
- Trial name
- NCT05411107
- Testing
- Biospecimen Collection, Bronchial Brush Biopsy, Bronchoscopy
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
COPD
Imaging Regional Lung Defect Severity
The purpose of this study is to develop and evaluate the usefulness of magnetic resonance imaging (MRI) using inert perfluorinated gases mixed with oxygen for regional assessment of pulmonary function.
- Trial name
- DIAL1001004 (NCT01640288)
- Testing
- Perfluorinated Gas/Oxygen Mixture, High Resolution CT of the Chest
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Hal C Charles
Respiratory Disorders
Study to Assess the Immunogenicity and Safety of GSK's Investigational Vaccine (GSK3277511A) When Given to Healthy Smokers and Ex-smokers After Administration of Shingrix Vaccine
This study will provide information regarding the sequential administration of two vaccines adjuvanted with AS01. The aim of this study is to understand immunogenicity and safety of NTHi-Mcat vaccine when administered…
- Trial name
- NCT03894969
- Testing
- GSK's investigational non-typeable Haemophilus influenzae (NTHi) and Moraxella catarrhalis (Mcat) multi-antigen vaccine (GSK3277511A) adjuvanted with AS01E, Shingrix GSK's lyophilized formulation of the herpes zoster (HZ) vaccine (GSK1437173A)
- Where
- 14 sites in Estonia, Finland and 3 more
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease, Cardiovascular Disease
Biomarkers of Early Chronic Obstructive Pulmonary Disease (COPD) in Smokers - Longitudinal Study
This is a longitudinal observational study to identify and validate protein biomarkers for COPD (chronic obstructive pulmonary diseases) and cardiovascular disease in smokers and ex-smokers attending primary care.
- Conditions
- Chronic Obstructive Pulmonary Disease, Cardiovascular Disease, Lung Cancer
- Trial name
- NCT02076061
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Lund University
Smoking
Glucobrassicin-Brussel Sprout Effect on D10 Phe Metabolism
To determine whether glucobrassicin-rich Brussels sprouts can favorably modify the metabolism of the polycyclic aromatic hydrocarbon deuterated phenanthrene ([D10]phe) in current and former smokers
- Trial name
- NCT02999399
- Testing
- Brussel Sprouts, Deuterated Phenanthrene
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Smoking Cessation
Escape Smoke Project: Non-Intervention Non-Drug Multicenter Study on the Real-life Effectiveness of Smoking Cessation in General Practice in Denmark
Real life smoking cessation rates after 24 weeks non-intervention design. Approximately 40 General Practice (GP) centers with 800 smokers will participate.
- Trial name
- ESCAPE SMOKE (NCT01544621)
- Testing
- Smoking cessation
- Volunteers
- 544 people, healthy volunteers welcome
- Sponsor
- Pfizer
Smoking Cessation
Interventions of Smoking Cessation During Pregnancy
The aim of this clinical trial is to test whether offering pregnant smokers a high intensity intervention for smoking cessation increases the rate of smoking cessation at the third trimester of pregnancy, compared to low…
- Trial name
- NCT01210118
- Testing
- Low intensity intervention, Higher intensity intervention
- Where
- 2 sites in Greece
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Hellenic Anticancer Society
Cardiovascular Disease, Oxidative Stress
Study of Chokeberry to Reduce Cardiovascular Disease Risk in Former Smokers
The purpose of this project is to determine whether chokeberry polyphenols mitigate cardiovascular disease risk in former smokers.
- Trial name
- NCT01541826
- Testing
- Chokeberry Extract, Chokeberry extract capsule, acute
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Smoking, Lung Cancer
Centralized Lung Cancer EARly Detection Among Smokers (CLEAR Study)
This trial studies how well a centralized care strategy works in improving the quality of smoking cessation and shared decision making among patients who smoke and are considering lung cancer screening.
- Trial name
- NCT04200534
- Testing
- Best Practice, Nicotine Patch, Quality-of-Life Assessment
- Where
- 3 sites in United States
- Volunteers
- 358 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Chronic Obstructive Pulmonary Disease (COPD), Smoking
The Natural History of Gene Expression in the Lung Cells of Non-Smokers, Smokers and Ex-Smokers in Health and Disease
Cigarette smoking is the major risk factor for chronic obstructive pulmonary disease (COPD, commonly known as chronic bronchitis and emphysema).
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Smoking, Smoking Cessation, Chronic Bronchitis
- Trial name
- NCT00974064
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Cigarette Smoking
Predictors of Teen Smoking-cessation
The primary objective of this research is to explore relations between impulsive behavior and smoking-cessation success among treatment-seeking teens enrolled in a quit-smoking program.
- Trial name
- NOT (NCT01141517)
- Testing
- Not-On-Tobacco smoking cessation program
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Cigarette Smoking
A Smoking Cessation Study to Understand the Biological and Functional Changes After One Year of Smoking Cessation
The purpose of this study was to understand the biological and functional changes after one year of smoking cessation and to collect data on a broad range of biomarkers of exposure (BoExp) and biomarkers of effect (BoE).
- Trial name
- RIBESC (NCT02432729)
- Where
- 5 sites in United States, Germany and 3 more
- Volunteers
- 1,184 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.