Clinical trials: Fortification
Neural Tube Defects, Folic Acid Deficiency
Feasibility, Acceptability and Directional Signal Effect on Blood Folate Levels of Iodized Salt Fortified With Folic Acid: Clinical Study
Aim 1: Assess directional signal of effect of fortified salt with folic acid and iodine on blood serum folate levels. It will be accomplished by feasibility pre-test/post-test clinical study by estimating mean and variability of…
- Conditions
- Neural Tube Defects, Folic Acid Deficiency, Fortification
- Trial name
- FASALT (NCT05935631)
- Testing
- Salt with folic acid and iodine
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Breast Milk Expression, Premature Birth of Newborn
How Effect Olive Oil and Eoprotin on Immunological Parameters and Growth
This study aims to compare immunologic parameters of 60 patients who are 1-28 days-aged, below 1500-gram body weight, born before 32 weeks of gestational age and fed with eoprotin or olive-oil fortified breast milk.
- Trial name
- RDS (NCT02832011)
- Testing
- olive oil, Eoprotin
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- nihat demir
Premature Birth, Breastmilk Collection
Targeted Nutrition for Moderate to Late Preterm Infants
This study will be comparing the postnatal growth of moderate to late preterm infants in the Neonatal Intensive Care Unit (NICU) born between gestational ages of 30 weeks 0 days to 35 weeks and 6 days who are receiving enteral…
- Conditions
- Premature Birth, Breastmilk Collection, Postnatal Growth Restriction
- Trial name
- NCT05515614
- Testing
- Targeted Fortification, Enfamil Liquid Human Milk Fortifier
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Pre-Term, Breast Milk Expression
Preemie Milk Analyser Validation Study
This study aims to test and validate the Preemie Ecosystem- a new device and associated software package for measuring the nutrient (fat, protein and carbohydrate) content of the breast milk of the mothers of premature babies.
- Conditions
- Pre-Term, Breast Milk Expression, Nutrition Disorder, Infant
- Trial name
- NCT06486194
- Testing
- Targeted breast milk fortification using preemie device, Standard Breast milk fortification
- Where
- United Kingdom
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Iron-deficiency, Absorption; Iron
Iron Absorption From Iron-enriched Aspergillus Oryzae
Ferrous sulfate is rapidly absorbed and the bolus of iron enters blood rather quickly possibly leading to higher concentrations of non-transferrin bound iron which induces oxidative stress.
- Conditions
- Iron-deficiency, Absorption; Iron, Anemia, Iron Deficiency, Bioavailability
- Trial name
- BIEFS (NCT03156712)
- Testing
- Ferrous sulfate
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Iron Deficiency
Iron Bioavailability From Cubes
Iron deficiency is a highly prevalent nutrient deficiency which is a public health problem, especially in developing countries. There are several strategies to correct iron deficiency in populations: besides supplementation with…
- Trial name
- Fe Bouillon (NCT02327299)
- Testing
- Bouillon fortified with FePP, Bouillon fortified with FePP + Stabilizer, Bouillon fortified with FeSO4
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Malnutrition
Optimal Amount of Zinc to Include in a Lipid-based Nutrient Supplement (LNS)
To assess zinc-related biochemical and functional responses among young Burkinabe children with a presumed high risk of zinc deficiency who receive micronutrient products containing different amounts of zinc, provided with or…
- Trial name
- NCT00944281
- Testing
- LNS-Zn5, LNS-Zn10, LNS-Zn0
- Where
- Burkina Faso
- Volunteers
- 3,220 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Vitamin D Deficiency, Low Bone Density
Nursing-Home Residents Given Bread Fortified With Vitamin D3
Background. For older adults, serum 25-hydroxyvitamin D (25(OH)D) higher than 75 nmol/L lowers fracture risk and attainment of this 25(OH)D target may require 125 mcg (5000 IU)/d of vitamin D3.
- Trial name
- NCT00789503
- Testing
- Bread fortified with vitamin D3 and calcium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Folate Deficiency, Vitamin B 12 Deficiency
Effectiveness of Fortification With Folic Acid and Vitamin B12 Among Teenage Girls
Folic acid and vitamin B12 play an interdependent role in key cellular processes, namely deoxyribonucleic acid synthesis, cell division, red blood cell formation, and nervous system myelination.
- Conditions
- Folate Deficiency, Vitamin B 12 Deficiency, Anemia, Megaloblastic, Cognitive Development
- Trial name
- NCT06100146
- Testing
- Folic acid and vitamin B12 fortified flour, Unfortified cereal flour
- Where
- 2 sites in Ethiopia
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- University Ghent
Type 2 Diabetes Mellitus
Vitamin D Receptor Polymorphisms and Efficacy of Vitamin D-Fortified Yogurt Drink in Patients With Type 2 Diabetes
Study is a 12-week Double blind,controlled experiments designed to examine the possible effects of vitamin D receptor gene polymorphisms on the metabolic, inflammatory and oxidative stress markers in type 2 diabetic patients to…
- Trial name
- NCT01236846
- Testing
- Fortified Yogurt Drink, Plain Yogurt Drink
- Where
- 4 sites in Iran
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Tirang R. Neyestani
Iron Deficiency (ID), Iron Absorption
Iron Absorption From Plant Heme Iron
Heme, an iron protoporphyin IX complex, consists of a ferrous ion captured in a porphyrin ring acting as a tetradentate ligand. The unique features of heme iron -its unusually high absorption in foods and its resistance to…
- Trial name
- PHIA (NCT07143890)
- Testing
- Iron chlorophyllin + no-matrix, SoyHb + no-matrix, FeSO4 + no-matrix
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- ETH Zurich
Malnutrition
Effect of Home-fortification With Sprinkles in Hematologic and Nutritional Status in Preschool Children in Medellín
Objective: To acquire the local scientific evidence, to evaluate the effects of micronutrient Sprinkles™ powder, both the nutritional status and haematological values in the vulnerable preschool population, to corroborate the…
- Trial name
- NCT01917032
- Testing
- Sachets containing a blend of micronutrients in powder form (Iron, Zinc, Folic Acid, Vitamin A and C), sprinkled onto home made food
- Where
- Colombia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- CES University
Urinary Iodine Status in School Aged Children
Iodine Status in Portuguese Children and the Role of Salt Fortification in School Canteens
It is well known that insufficient iodine intakes impairs the production of thyroid hormones, essential for cognitive development and healthy growth.
- Trial name
- IoGeneration (NCT02608138)
- Testing
- Iodine status among portuguese school children
- Where
- Portugal
- Volunteers
- 2,018 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Anemia, Iron Deficiency
Iron and Prebiotics Fortification in Kenyan Infants
Iron deficiency and anemia are health issues affecting mainly infants and women in developing countries. Iron deficiency in infancy can have long-lasting impact on cognitive and motor development of the child.
- Conditions
- Anemia, Iron Deficiency, Diarrhea, Malaria
- Trial name
- Iro'n'Pre (NCT02118402)
- Testing
- Fortified maize porridge
- Where
- Kenya
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Bioavailability
Iron Bioavailability From Cereal-based Foods
Iron-deficient anemia is a chronic problem in sub-Saharan Africa and other developing areas of the world. From our previous research, the investigators have shown that certain local plant foods in Kenya and Senegal have an…
- Trial name
- NCT05061290
- Testing
- Control Porridge, Reference Porridge A, Test Porridge B
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Purdue University
Premature Infants
Targeted Protein Fortification in Extremely Low Birth Weight Preterm Infants
While new innovations in the care of extremely premature infants have led to decreased morbidity and mortality, poor postnatal growth remains as a major challenge.
- Trial name
- NCT02943746
- Testing
- Standard Protein Diet, High Protein Diet
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Cardiovascular Risk Factor, Inflammation
Assessment of a New Food Product in Metabolically at Risk Children
The current study conducted will lend toward the optimization of the development of a food product that will promote a shift towards improved metabolic health.
- Conditions
- Cardiovascular Risk Factor, Inflammation, Micronutrient Deficiency
- Trial name
- NCT03175003
- Testing
- Food Product
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Healthy Volunteers, Nitric Oxide
Evaluation of Adding Nitrate Into Foods for Regulating Nitric Oxide Bioavailability in Healthy Individuals
Inorganic nitrate, found in leafy green vegetables and beetroot, can help lower blood pressure and support heart health. Early experimental work has suggested that dietary nitrate supplementation, in the form of beetroot juice or…
- Conditions
- Healthy Volunteers, Nitric Oxide, Vascular Function
- Trial name
- NCT07172425
- Testing
- Inorganic potassium nitrate-fortified biscuits supplementation, Inorganic potassium nitrate-fortified cereal bar supplementation, Inorganic potassium nitrate-fortified porridge supplementation
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Iron Deficiency and Anemia
Feeding Trial of Bio-fortified Pearl Millet
The objective of this study was to evaluate the efficacy of iron bio-fortified pearl millet in improving iron status in adolescents in India.
- Trial name
- NCT02152150
- Testing
- Iron bio-fortified pearl millet, Control pearl millet
- Where
- India
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Cornell University
Iron Deficiency, Iron Deficiency Anemia
Effect of Iron Fortified Wheat Flour on Cognition and Iron Status in Indian School Children
This study is designed to evaluate the efficacy of NaFeEDTA-fortified whole wheat flour in improving cognition, hemoglobin, iron status and total body iron among school children in urban Bangalore.
- Conditions
- Iron Deficiency, Iron Deficiency Anemia, Cognition
- Trial name
- NCT00741143
- Testing
- Fortification of wheat flour with NaFeEdta
- Where
- India
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- St. John's Research Institute