Clinical trials: Fortification
Iron-deficiency, Vitamin A Deficiency
Sub Regional Micronutrient Survey in Ethiopia
To conduct a sub-regional micronutrient survey (SRMNS) assessing the prevalence of vitamin A, Zn, and Fe status in the country
- Conditions
- Iron-deficiency, Vitamin A Deficiency, Zinc Deficiency
- Trial name
- NCT03353662
- Testing
- Women of Gamo Gofa, Children of Gamo Gofa, Women of West Gojjam
- Where
- 2 sites in Ethiopia, Switzerland
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Anemia, Malnutrition
Acceptability of Lipid-Based Nutrient Supplements (LNS) for Women and Infants
Inadequate micronutrient intakes during pregnancy, lactation and infancy remain a major problem in Ghana. Lipid-based nutrient supplements (LNS) made using vegetable oil, groundnut paste, milk, sugar, and micronutrients may offer…
- Trial name
- NCT00970840
- Testing
- LNS-20gM or LNS-P&L
- Where
- Ghana
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Anemia, Iron Deficiency
Effect of Timing of Micronutrient Powder Consumption on Iron Absorption in Infants
Infants and young children in sub-Saharan Africa have high rates of iron deficiency anemia (IDA), which adversely affects their growth and cognitive development.
- Trial name
- NCT02989311
- Testing
- Fortified maize porridge (MNP and Iron), Fortified Maize porridge (MNP + Iron + GOS)
- Where
- Kenya
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Child Malnutrition, Feeding Behavior
Nutrition Intervention Integrated With Food Voucher to Improve Child Growth and Feeding Practices
Brief Summary: Background: The period from birth to two years of age is the "critical window" for the promotion of optimal growth, health, and development.
- Conditions
- Child Malnutrition, Feeding Behavior, Growth; Stunting, Nutritional
- Trial name
- NCT03641001
- Testing
- Child feeding counselling, food voucher, micronutrient powder, WASH
- Where
- Bangladesh
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Iron Deficiency, Anaemia
Iron & Alginate Study
Iron deficiency anaemia affects around two billion people worldwide. Food fortification with iron is a realistic way to combat this problem.
- Trial name
- NCT01528644
- Testing
- alginate beads containing ferrous gluconate, ferrous gluconate in a capsule, ferrous gluconate in a capsule in presence of calcium
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Neural Tube Defects, Folic Acid Deficiency
Using Iodized Salt to Improve Serum Folate, B12 and Iron Levels
Question: How effective is fortified iodized salt in increasing serum concentrations of folate, B12 and iron among non-pregnant and non-lactating women of reproductive age? Hypothesis: Micronutrient fortified iodized salt can…
- Conditions
- Neural Tube Defects, Folic Acid Deficiency, Spina Bifida, Anencephaly-Spina Bifida
- Trial name
- NCT06904612
- Testing
- Micronutrient fortified iodized salt
- Where
- 2 sites in United States, India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hydrocephalus and Neuroscience Institute
Healthy
Efficacy of Multiple Micronutrient Fortified Biscuits and Deworming in Vietnamese School Children
The aim of this study is to identify the effect of a school-based food fortification intervention with multi-micronutrients with or without deworming to improve anemia, micronutrient status, cognitive function, health (morbidity…
- Trial name
- NCT00728273
- Testing
- worm treatment and multiple micronutrient fortified biscuits
- Where
- Thailand
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Neys-van Hoogstraten Foundation, The Netherlands
Iodine Deficiency Disorders
RCT of Iodine-containing MNPs vs Oral Iodized Oil to Prevent Iodine Deficiency in Weaning Infants
In this study, two intervention strategies to address iodine deficiency and prevent iodine deficiency disorders in breast-fed weaning infants will be evaluated in a mild to moderate iodine-deficient population in Zamboanga del…
- Trial name
- NCT02421653
- Testing
- MNP90, MNP45, IODISED OIL
- Volunteers
- healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Food Insecurity, Stunting
Scaling up Small-Scale Food Processing to Promote Food Security Among Women Farmers in Rural Vietnam
This repeated measures, cluster randomized, cohort trial design was carried out in three provinces in the northern mountainous area of Vietnam.
- Conditions
- Food Insecurity, Stunting, Wasting, Underweight
- Trial name
- NCT03847662
- Volunteers
- 799 people, healthy volunteers welcome
- Sponsor
- National Institute of Nutrition, Vietnam
Anemia
Treatment of Iron Deficiency Anemia in Malaria Endemic Ghana
Iron deficiency and iron deficiency anemia (IDA) are the most prevalent micronutrient deficiencies on a worldwide basis, especially in developing countries.
- Trial name
- NCT01001871
- Testing
- Sprinkles®, vitamin/mineral fortificant without iron
- Where
- Ghana
- Volunteers
- 3,880 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Malnutrition, Diarrhea
WASH Benefits Bangladesh
Brief Summary: The purpose of this study is to measure the independent and combined effects of interventions that improve water quality, sanitation, hand washing, and nutrition on child growth and development in the first years…
- Conditions
- Malnutrition, Diarrhea, Child Development
- Trial name
- NCT01590095
- Testing
- Water quality, Sanitation, Hand washing
- Where
- Bangladesh
- Volunteers
- 5,040 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Zinc Deficiency
Impact of Mass Zinc Fortification Programs on Plasma Zinc Concentration
The purpose of the study is to evaluate the use of plasma zinc concentration for assessing the impact of mass zinc fortification programs.
- Trial name
- NCT00944723
- Testing
- Zinc-fortified bread, Zinc supplement, Non-fortified bread
- Where
- Senegal
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Very Preterm Infant, Very Low Birthweight
LIFT-UP: Randomized Controlled Trial of Fortification of Human Milk
The goal of the LIFT-UP randomized controlled trial is to evaluate the efficacy of feeding routinely and fortified human milk using a standardized clinical protocol to very low birthweight (VLBW) or very preterm (VPT) infants in…
- Trial name
- LIFT-UP RCT (NCT06765863)
- Testing
- Human Milk Fortifier, Volume targets
- Where
- 4 sites in India
- Volunteers
- 776 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Healthy
The Bread Trial: Effects of Bread Fortified With Folic Acid and Vitamin B12
In the Netherlands fortification of food products is not yet mandatory. One of the major arguments of the Dutch Health Council to advise against mandatory fortification is the possibility of masking of a vitamin B12 deficiency.
- Trial name
- NCT00353353
- Testing
- consumption of fortified bread
- Where
- Netherlands
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Wageningen Centre for Food Sciences
Preterm Birth
Human Milk in Preterm Infants
Current NICU protocol introduces human milk fortifier at 8 days of feeding. This study will introduce human milk fortifier at day 1. The primary outcome is the effect on growth velocity at 28 days and 36 weeks post menstrual age.
- Trial name
- NCT05228535
- Testing
- Human milk fortifier
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Augusta University
Child Malnutrition
Efficacy of a Multiple Micronutrient-Fortified Lipid-Based Nutrient Supplement for Children Under Two in Cambodia
The purpose of this trial is to evaluate the efficacy of the LNS on children aged 6-17 months in preventing growth faltering and improving micronutrient status.
- Trial name
- NCT02257762
- Testing
- LNS, Corn-soy blend ++ (CSB++), Sprinkles
- Where
- Cambodia
- Volunteers
- 487 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche pour le Developpement, Cambodia
Vitamin B 12 Deficiency
Effect of Daily Consumption of Vitamin B12 Fortified Yoghurt on Vitamin B12 Status in Older Adults
Older adults are recommended to meet their daily vitamin B12 (B12) requirements by consuming foods with added B12 and/or taking B12 supplements (i.e.
- Trial name
- NCT05993962
- Testing
- Fortified yoghurt, Control yoghurt
- Where
- 2 sites in Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Malnutrition, Diarrhea
WASH Benefits Kenya
The purpose of this study is to measure the independent and combined effects of interventions that improve sanitation, water quality, handwashing, and nutrition on child health and development in the first years of life.
- Conditions
- Malnutrition, Diarrhea, Child Development
- Trial name
- WASHB-Kenya (NCT01704105)
- Testing
- Water Quality, Sanitation, Handwashing
- Where
- Kenya
- Volunteers
- 8,246 people, healthy volunteers welcome
- Sponsor
- Innovations for Poverty Action
Very Preterm Infant, Very Low Birth Weight Infants
The Use of Early Fortification in Preterm Infants
Very premature or very low birth weight (VLBW) infants are at risk of suboptimal growth after birth, making adequate nutrition essential.
- Trial name
- NCT07861984
- Testing
- Early Fortification, Standard Fortification
- Where
- Indonesia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Micronutrient Deficiencies
Effect of Sprinkles With and w/o Fe on Zn Absorption in Kenyan Toddlers
The investigators propose to study the effects of increased iron intake by home fortification of complementary foods on the gastrointestinal microbial development, inflammatory responses, and zinc (Zn) absorption.
- Trial name
- NCT02101723
- Testing
- MNP + Zn/Fe, MNP + Zn
- Where
- 2 sites in United States, Kenya
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver