Clinical trials: Fracture of Lower Limb
Tibial Plateau Fracture
Comparison of Functional Outcome Between Locking Plate Technique Versus Hybrid Ilizarov Technique in Patients With Schatzker Type V and VI Tibial Plateau Fractures
This comparative clinical study will evaluate and compare the functional outcomes of patients with Schatzker type V and VI tibial plateau fractures treated using either the locking plate technique or the hybrid Ilizarov…
- Trial name
- TPF (NCT07773402)
- Testing
- Hybrid Ilizarov Fixation, Locking Plate Fixation
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Prof. Sajjad Hussain Goraya
Hip Fractures, Osteoporosis
Effect of a Multicomponent Intervention on Functional Capacity After Hip Fracture
Due to the clinical, functional, cognitive and social complexity of older adults after fragility hip fractures (defined as those produced by low-impact trauma), the investigators propose an intervention.
- Conditions
- Hip Fractures, Osteoporosis, Fall, Frailty Syndrome
- Trial name
- ActiveFLS (NCT05435534)
- Testing
- ActiveFLS intervention, Usual care group
- Where
- Spain
- Volunteers
- 174 people
- Sponsor
- Fundacion Miguel Servet
Femoral Neck Fractures, Intertrochanteric Fracture
Intramedullary Nail Versus Sliding Hip Screw Inter-Trochanteric Evaluation
The purpose of this study is to assess the impact of Gamma3 intramedullary nails versus sliding hip screws on health-related quality of life as measured by the EuroQuol-5D at 52 weeks in individuals with trochanteric fractures.
- Trial name
- INSITE (NCT01380444)
- Testing
- Gamma3 Intramedullary Nails (Stryker), Sliding Hip Screws
- Where
- 26 sites in United States, Australia and 10 more
- Volunteers
- 880 people
- Sponsor
- Stryker Trauma and Extremities
Fractures, Bone, CKD Stage 4
The Effect of Prophylactic Anticoagulation on Major Bleeding Events in Hospitalized Chronic Kidney Disease and Lower Limb Fracture Patients.
the risk of bleeding may be greater than the benefit of antithrombotic protection when prophylactically anticoagulating a patient with a lower limb fracture and advanced CKD.
- Conditions
- Fractures, Bone, CKD Stage 4, CKD Stage 3, CKD Stage 5
- Trial name
- FAA (NCT06795698)
- Testing
- Enoxaparin
- Where
- Mexico
- Volunteers
- 61 people
- Sponsor
- Hospital Civil de Guadalajara
Hip Fractures, Clopidogrel, Poor Metabolism of
Aggregometry in Elderlies With Hip Fracture and Receiving Clopidogrel
In elderly patients, hip fracture should be surgically treated within 48 hours from admission, since its deferral worsens the mortality.
- Conditions
- Hip Fractures, Clopidogrel, Poor Metabolism of, Anesthesia
- Trial name
- NCT04642209
- Testing
- Aggregometry
- Where
- Italy
- Volunteers
- 9 people
- Sponsor
- University Magna Graecia
Trochanteric Fracture of Femur, Osteoporotic Fracture of Femur
FARE Augmentation of Proximal Femoral Fractures With CaS/HA and Systemic ZA
The goal of this clinical trial is to investigate the new bone formation around a metal device in the femoral head in patients with osteoporotic hip fractures undergoing surgical treatment with nails.
- Conditions
- Trochanteric Fracture of Femur, Osteoporotic Fracture of Femur, Hip Fractures, Bone Density, Low
- Trial name
- NCT06135298
- Testing
- OSTEOSYNTHESIS, Zoledronic acid, CERAMENT BONE VOID FILLER (BVF)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Aksaray University
Hip Fracture, Postoperative Pain
Effect of PENG Block on Postoperative Tramadol Consumption in Partial Hip Prosthesis Surgery
This study aims to evaluate the effect of ultrasound-guided pericapsular nerve group (PENG) block on postoperative tramadol consumption, pain scores, and clinical outcomes in patients undergoing partial hip prosthesis surgery.
- Trial name
- PENG-PKP (NCT07534137)
- Testing
- PENG Block, General Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- University of Gaziantep
Hip Fractures
Anesthesia And Post-operative Mortality After Proximal Femur Fractures
This study evaluates the effect of anesthesia on mortality after surgical repair of proximal femur fracture. Patients will receive either a subarachnoid block or a combination of peripheral nerve blocks and light general…
- Trial name
- NCT02406300
- Testing
- Subarachnoid Anesthesia, PNB/GA, ropivacaine
- Where
- Portugal
- Volunteers
- 57 people
- Sponsor
- Centro Hospitalar do Porto
Fracture Neck of Femur, Hip Fracture
Early Functional Outcome of Operative Treatment of Displaced Femoral Neck Fractures in Two Kenyan Orthopaedic Centres
This was a prospective cohort study. The study was conducted in the two hospitals after approval by the KNH/UON ethical committee and the board of management of Kikuyu Mission Hospital.
- Conditions
- Fracture Neck of Femur, Hip Fracture, Femoral Neck Fracture
- Trial name
- NCT04879472
- Testing
- Osteosynthesis
- Volunteers
- 60 people
- Sponsor
- University of Nairobi
Hip Fractures, Acute Post Operative Pain
PENG vs SIFI Block for Positioning Pain During Spinal Anesthesia
This study aims to compare the effectiveness of preoperative ultrasound-guided suprainguinal fascia iliaca compartment block (SFICB) and pericapsular nerve group block (PENG) in preventing positioning pain during spinal…
- Conditions
- Hip Fractures, Acute Post Operative Pain, Nerve Block, Spinal Anesthesia
- Trial name
- NCT05549011
- Testing
- PENG Block, SIFI compartment block, Numeric Rating Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Hip Fractures, Acute Kidney Injury
Evaluation of Novel Biomarkers in Early Recognition of Acute Kidney Injury After Orthopedic Operations.
Surgical treatment of hip fracture may be complicated by acute kidney injury. The aim of this study is to investigate whether the investigators can find a better biomarker than creatinine to recognize this problem at an earlier…
- Trial name
- NCT05285709
- Testing
- Biomarker, RRI measurement
- Where
- 2 sites in Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Warsaw
Muscle Atrophy, Muscle Weakness
Evaluating Muscle Function After Ankle Surgery
Patients who are forced to rest or reduce activity as a result of illness, injury, or surgery often experience resulting muscle weakness.
- Conditions
- Muscle Atrophy, Muscle Weakness, Fractures
- Trial name
- NCT00060970
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hip Fracture, Postoperative Pain
Comparison of Meta-PENG and Suprainguinal Fascia Iliaca Plane Block in Hip Fractures
This prospective observational single-center study will compare the effects of ultrasound-guided meta-PENG block and suprainguinal fascia iliaca plane block in patients undergoing hip fracture surgery under spinal anesthesia.
- Conditions
- Hip Fracture, Postoperative Pain, Regional Anesthesia
- Trial name
- META-SIFI (NCT07612761)
- Testing
- Ultrasound-Guided Meta-PENG Block, Ultrasound-Guided Suprainguinal Fascia Iliaca Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Osteonecrosis, Femoral Neck Fracture
A Comparison of Two Different Surgical Techniques in Hip Resurfacing Arthroplasty
The purpose of the study is to compare two different surgical techniques in hip resurfacing arthroplasty (RHA), comparing bloodflow and metabolism in the femoral head, as well as implant migration, periprosthetic bone mineral…
- Conditions
- Osteonecrosis, Femoral Neck Fracture, Implant Failure
- Trial name
- NCT00913679
- Testing
- Surgical approach (ReCap Hip Resurfacing System)
- Where
- Denmark
- Volunteers
- 49 people
- Sponsor
- University of Aarhus
Tibial Plateau Fracture, Pain, Postoperative
Duloxetine Tibial Plateau
The purpose of this study is to determine if Duloxetine provides effective pain management for adult patients (18 or older) undergoing tibial plateau surgery.
- Trial name
- NCT04639011
- Testing
- Duloxetine, Standard of care (SOC) for tibial plateau surgery
- Where
- 2 sites in United States
- Sponsor
- Boston Medical Center
Ankle Fractures, Tibia Fracture
CBD for Pain Reduction and Opioid Use After Ankle and Tibia Fracture ORIF
The purpose of this study is to evaluate the effects of administering CBD to control post-operative pain in patients undergoing ankle fracture open reduction and internal fixation, tibial plafond (pilon) open reduction and…
- Trial name
- NCT04768478
- Testing
- CBD
- Where
- United States
- Sponsor
- NYU Langone Health
Osteoarthritis, Hip, Fracture of Hip
Post Market Clinical Follow-Up of the Zimmer Stafit Acetabular System
This study is a Post Market Clinical Follow up study to fulfil the post market surveillance obligations according to Medical Device Directive and European Medical Device Vigilance System (MEDDEV) 2.12-2.
- Conditions
- Osteoarthritis, Hip, Fracture of Hip, Avascular Necrosis of Hip, Dislocated Hip
- Trial name
- NCT04079114
- Testing
- Patients who received the Stafit Acetabular System
- Volunteers
- 166 people
- Sponsor
- Zimmer Biomet
Anticoagulants; Circulating, Hemorrhagic Disorder, Femoral Neck Fractures
Evaluation of Perioperative Management of Curative Anticoagulants in the Geriatric Perioperative Unit in Patient Hospitalized for Femoral Neck Fracture.
Pilot study to evaluate the management of curative anticoagulant prescriptions pre- and postoperatively in elderly patients hospitalized for femoral neck fracture.
- Trial name
- ANTICOGER (NCT05286671)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Hip Fractures, Sensitivity
CT Scan in Per-trochanteric Fractures
To assess the importance Of Ct scan in the prediction of fixation failure of per-trochanteric fractures
- Conditions
- Hip Fractures, Sensitivity, Computed Tomography Scan
- Trial name
- NCT04091776
- Testing
- CT scan
- Volunteers
- 60 people
- Sponsor
- Ahmed Saeed Younis
Hip Fractures
Cluster-randomized Study of 394 Patients Operated With Direct Anterolateral Approach.
394 participants were cluster-randomized during 2010-2014. Depending on which ward the participants admitted to, they were allotted to free rehabilitation (non-precaution group, NPG, n=226) or our conventional regime with…
- Trial name
- NCT03468192
- Testing
- Non-precaution group
- Volunteers
- 394 people
- Sponsor
- Lund University
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