Clinical trials: Fracture of Lower Limb
Hip Fractures, Gait Disorders in Old Age
Clinical Study of the Effects of a SWalker II and VR for Hip Fracture Rehabilitation in the Elderly
This project is structured in two distinct phases. The first phase deals with the recovery of the hip fracture in the acute phase up to ambulation, and the second is understood as the continuation of functional improvement of…
- Trial name
- SWalker-VR (NCT06025981)
- Testing
- Preliminary Phase, Phase I - Early gait rehabilitation, Phase II - Maintenance gait function ( with VR)
- Where
- 2 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Werium Assistive Solutions
Femur Fracture
Comparative Study Between (MIPO)Submuscular Plate Fixation of Fracture Femur and Conservative Management With Thomas Splint in Children From 5 to 8 Years Old: A Randomized Clinical Study
This randomized clinical study compares the outcomes of two treatment methods for femur fractures in children aged 5 to 8 years: Minimally Invasive Plate Osteosynthesis (MIPO) using submuscular plate fixation and conservative…
- Trial name
- NCT06543901
- Testing
- Submuscular plating, Traction and casting
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kasr El Aini Hospital
Sarcopenia in Elderly, Frailty
Safety and Efficacy of Isomyosamine in Reducing Inflammation and Treating Muscle Loss in Older Adults After Hip or Thigh Bone Fractures
This Phase II clinical study investigates the safety and effectiveness of a new drug, Isomyosamine, in patients with sarcopenia or frailty, conditions associated with aging and muscle weakness.
- Conditions
- Sarcopenia in Elderly, Frailty, Frailty/Sarcopenia, Frailty in Older Adults
- Trial name
- NCT06942182
- Testing
- Isomyosamine 250mg
- Volunteers
- 60 people
- Sponsor
- TNF Pharmaceuticals, Inc.
Fracture of Tibia
Conservative Versus Intramedullary Nailing for Pediatric Tibial Shaft Fractures
Tibial shaft fracture is a common fracture in the pediatric and adolescent population. The outcomes of both conservative and operative treatment are not clear and to date there is no randomized prospective trial comparing…
- Trial name
- CINPED (NCT05501496)
- Testing
- intramedullary nailing, casting
- Where
- 2 sites in Finland
- Volunteers
- 66 people
- Sponsor
- Turku University Hospital
Infection
VeraFlo With Prontosan® and Wound and Fracture Healing.
To answer the question: "Do Prontosan instillations decrease time to wound and fracture healing and decrease bacterial load compared to wound vac treatment without Prontosan?," we will enroll up to 30 subjects (for an anticipated…
- Trial name
- NCT02621073
- Testing
- VeraFlo with Prontosan, V.A.C Ulta System
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Brett Crist
Ankle Fractures
Hardware Removal After ORIF of Ankle Fractures
Ankle fractures account for 10 % of fractures in the adult population. A part of patients (40%) is treated surgically. After healing of the fractures, about one year after the operation, a surgery is often performed to remove the…
- Trial name
- NCT05798741
- Testing
- Hardware removal
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Hôpital Fribourgeois
Hip Fracture
Institutional Registry of Hip Fracture in the Elderly
The purpose of this study is to create an institutional and population-based registry of Hip fracture in the elderly with a prospective survey based on epidemiological data, risk factors, diagnosis, prognosis, treatment…
- Trial name
- NCT02279550
- Where
- Argentina
- Volunteers
- 2,000 people
- Sponsor
- Hospital Italiano de Buenos Aires
Toddler's Fracture
Toddlers Fractures - Cast Versus Removable Boot
A toddler's fracture is a fracture that occurs in the lower leg, oven the shin, of children 9 months to four years of age. It usually happens when a young child twists the leg while running or jumping.
- Trial name
- NCT03971448
- Testing
- LPWB, AKWC
- Where
- Canada
- Volunteers
- 129 people
- Sponsor
- The Hospital for Sick Children
Hip Fracture
Ultrasound Guided Blockade of the Lumbar Plexus - the Supra Sacral Parallel Shift
Anesthesia for hip surgery can be performed with ultrasound guided blockade of the mesh of nerves (the lumbar plexus) supplying the hip region from the lumbar spinal nerves.
- Trial name
- SSPS (NCT01669018)
- Testing
- Lumbar plexus block using LUT technique, Lumbar plexus block using SSPS technique
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Postoperative Cognitive Dysfunction, Hip Fractures
The Comparison of Cognition, Depression and Anxiety, and Quality of Life After Hip Fracture Surgery Under General or Regional Anesthesia
Postoperative cognitive dysfunction is a relatively common in elderly patients after hip surgery, but exact mechanism of its onset is still unclear as well as contributing factors.
- Conditions
- Postoperative Cognitive Dysfunction, Hip Fractures, Depression, Anxiety, Quality of Life
- Trial name
- NCT04518839
- Volunteers
- 140 people
- Sponsor
- University of Zagreb
Hip Fractures, Complication of Traction Procedure
Skin Traction Versus Position Splint in Patients With Hip Fracture
The aim of this prospective, randomized controlled trial is to compare the effects of preoperative skin traction and position splint on pain, comfort, complications, difficulty level of nursing interventions, satisfaction from…
- Conditions
- Hip Fractures, Complication of Traction Procedure, Pain, Splints
- Trial name
- NCT02287571
- Testing
- Derotation splint, elastic bandage
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Tibial Fracture
Assessment of the Verus Frame in Tibial Intramedullary Nailing
This prospective, single-arm Post-Market Clinical Follow-Up (PMCF) study, utilizing a registry-based control group, will assess the Verus frame's effectiveness in achieving precise tibial rotation and alignment during…
- Trial name
- NCT07362121
- Testing
- Verus frame to stabilize tibia
- Where
- Finland
- Volunteers
- 25 people
- Sponsor
- Hemitec Finland Oy
Lower Extremity Fracture
Suture Versus Staples for Wound Closure in Orthopaedic Trauma Surgery
This pilot study is designed to assess the feasibility of comparing skin closure methods - sutures versus staples - and subsequent rates of surgical site infection following open reduction and internal fixation surgery for…
- Trial name
- SvS (NCT06586814)
- Testing
- Suture, Staple
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Southern California
Osteoporosis, Arthroplasty Complications
Surgeon-Initiated Bone Health Referral Pathway in Patients Undergoing Lower Extremity Arthroplasty
The goal of this clinical trial is to observe the impact of a surgeon-driven bone health referral pathway following lower extremity arthroplasty.
- Conditions
- Osteoporosis, Arthroplasty Complications, Fragility Fracture
- Trial name
- NCT05845021
- Testing
- Surgeon-Initiated Bone Health Referral Pathway
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Osteoarthritis, Rheumatoid Arthritis
Project JAY THA Registration Study
This is a prospective, randomized, multicenter clinical study in Chinese subjects to compare the safety and efficacy of the Delta PLUS Femoral Head and SL-TWIN Stem with BIOLOX forte ball head and SL-PLUS Stem in total hip…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Avascular Necrosis
- Trial name
- NCT02347384
- Testing
- Delta PLUS Femoral Head + SL-TWIN Stem, BIOLOX forte ball head + SL-PLUS Stem
- Where
- 4 sites in China
- Volunteers
- 100 people
- Sponsor
- Smith & Nephew Orthopaedics (Beijing) Limited
Hip Fracture
Preoperative Biochemical Predictors of Outcome in Patients With Hip Fracture
The objective of the study is to identify biochemical predictors of morbidity and mortality in patients suffering from hip fracture.
- Trial name
- NCT01280253
- Where
- Sweden
- Volunteers
- 999 people
- Sponsor
- Region Skane
Hip Fractures
Hip Abductor Muscle Dysfunction After Nailing of Proximal Femoral Fractures, Incidence and Contributing Factors.
Proximal femoral fractures(PFFs) are common with advancing age. Proximal femoral nail (PFN) is now increasingly used to fix unstable fractures.
- Trial name
- NCT04311892
- Testing
- EMG of the hip abductor muscles
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- South Valley University
Intertrochanteric Fracture, Hip Fracture
Intertrochanteric Femoral Fracture Fixation Trial
The main goal of the study is to determine which cephalomedullary nail results in a better functional outcome for the patient with an unstable intertrochanteric hip fracture.
- Trial name
- NCT02627040
- Testing
- InterTan Intertrochanteric Nail, Gamma 3 Intertrochanteric Nail
- Where
- 2 sites in United States
- Volunteers
- 95 people
- Sponsor
- Florida Orthopaedic Institute
Ankle Fractures, Intermittent Pneumatic Compression
Preoperative Treatment of Malleolar Fractures
This study investigates, in a randomized setting, the use of intermittent in-cast pneumatic foot-compression (IPC) in the preoperative treatment of malleolar fractures.
- Conditions
- Ankle Fractures, Intermittent Pneumatic Compression, Comparative Study, Preoperative Care
- Trial name
- NCT02444468
- Testing
- Flowtron ACS800, Bandage
- Where
- Denmark
- Volunteers
- 96 people
- Sponsor
- Hospital of Southern Jutland
Tibia Fracture
Unreamed Intramedullary Tibial Nailing in Treatment of Open IIIa Diaphyseal Tibial Fractures in Adults
To study the incidence of non union of Unreamed intramedullary nailing in type IIIa Open diaphyseal fractures of the tibia as a primary outcome and the incidence of complications and clinical and functional outcome as a secondary…
- Trial name
- NCT06280417
- Testing
- Unreamed intramedullary tibial nail
- Volunteers
- 25 people
- Sponsor
- Assiut University
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