Clinical trials: Fracture of Lower Limb
Trauma Injury
SFDI in High Energy Lower Extremity Fracture
This is a non-randomized prospective study of 20 patients with high energy lower extremity fractures evaluating feasibility and acceptability of SFDI, a real-time optical imaging technology.
- Trial name
- NCT05635617
- Testing
- Lower Extremity Surgery
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Lower Extremity Fracture
Diffusion Length of Local Anesthetics in the Subparaneural Space and Duration of Analgesia
Ultrasound-guided popliteal sciatic nerve block is a widely practiced technique to provide anesthesia or analgesia for below-knee surgeries.
- Trial name
- NCT05437835
- Testing
- Ropivacaine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- General Hospital of Ningxia Medical University
Hip Fracture, Disability
Efficacy of a Post-Rehabilitation Exercise Intervention
Background: Many people who have suffered a hip fracture are discharged from rehabilitation services with significant residual functional limitations and disability.
- Trial name
- NCT00592813
- Testing
- Enhanced Strong for Life, cardiovascular nutrition education
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- Boston University
Rheumatoid Arthritis, Osteoarthritis
G7 BiSpherical Acetabular Shell PMCF Study
The primary objective of this study is to obtain implant survivorship and clinical outcomes data for the commercially available G7 BiSpherical Acetabular Shell.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Noninflammatory Degenerative Joint Disease, Avascular Necrosis
- Trial name
- NCT03266874
- Where
- 5 sites in France, Germany and 2 more
- Volunteers
- 160 people
- Sponsor
- Zimmer Biomet
Femur Fracture
Radiographic Influences of Bisphosphonate Treatment on Femur
Although there is strong evidence that bisphosphonates prevent certain types of osteoporotic fractures, there are concerns that these medications may be associated with rare atypical femoral fractures (AFF).
- Trial name
- NCT01969279
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Tomidahama Hospital
Hip Fractures, Clinical Pharmacists
The Influence of Clinical Pharmacist on the Quality of Drug Prescribing and Rehabilitation Outcomes in Post-acute Hip Fractured Patients
The influence of clinical pharmacist on various drug related outcomes was reported in different healthcare setting including the community, long term care and during acute hospitalization.
- Conditions
- Hip Fractures, Clinical Pharmacists, Rehabilitation Outcome
- Trial name
- NCT04360746
- Testing
- Pharmaceutical intervention, Rehabilitation
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Rabin Medical Center
Osteoarthritis, Rheumatoid Arthritis
Retrospective Study of the Linear™ Hip
The purpose of this study is to evaluate the use and efficacy of the Encore Linear™ Hip System in a group of 200 patients for whom data has already been collected.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Femoral Fracture, Correction of a Functional Deformity
- Trial name
- NCT00764959
- Testing
- Encore Linear™ Hip System
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Encore Medical, L.P.
Non-inflammatory Degenerative Joint Disease, Osteoarthritis
Study to Evaluate the Safety and Effectiveness of REAL INTELLIGENCE™ CORI™ in Unicondylar Knee Arthroplasty (UKA) Procedures
This is a prospective study to demonstrate the safety and effectiveness of CORI and to register CORI in China mainland.
- Conditions
- Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Requires Correction of Functional Deformity
- Trial name
- CORI RCT UKA (NCT04797897)
- Testing
- CORI, Conventional
- Where
- 3 sites in Australia, Hong Kong and 1 more
- Volunteers
- 4 people
- Sponsor
- Smith & Nephew, Inc.
Ankle Fractures
Robot-assisted Rehabilitation of Ankle Fractures: Efficacy and Comparison With Traditional Methods
The purpose of this trial is to determine the effectiveness, safety and tolerability of robot-assisted rehabilitation using ARBOT in patients with ankle dysfunction resulting from work related ankle fractures, compared with…
- Trial name
- NCT02923479
- Testing
- Specific ankle rehabilitation by ARBOT device, General Rehabilitation, Specific ankle rehabilitation performed by physiotherapist
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Istituto Nazionale Assicurazione contro gli Infortuni sul Lavoro
Ankle Injuries, Fracture
Lymphomyosot for Ankle Edema Following Fracture
Ankle fractures are invariably complicated by severe soft-tissue swelling which can significantly prevent surgical repair (open reduction and internal fixation - ORIF) of the fractured bone for up to two weeks.
- Trial name
- NCT00884988
- Testing
- Lymphomyosot
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Shaare Zedek Medical Center
Venous Thromboembolism
Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Thromboembolism in Patients Undergoing Hip Fracture Surgery
The primary objective was to compare the efficacy of once daily [q.d] subcutaneous [s.c.] injections of Semuloparin sodium (AVE5026) with q.d. s.c.
- Trial name
- SAVE-HIP2 (NCT00721760)
- Testing
- Enoxaparin sodium, Semuloparin sodium
- Where
- 25 sites in United States, Argentina and 23 more
- Volunteers
- 1,003 people
- Sponsor
- Sanofi
Femoral Fractures, Hip Fractures
A Study to Evaluate the Safety and Effectiveness of TRIGEN™ INTERTAN™ (10S Models)
This is a post-market study to evaluate the revision rate of femoral fractures, treated with INTERTAN 10S Nails at one-year post-operation.
- Trial name
- NCT04865146
- Testing
- TRIGEN™ INTERTAN™
- Where
- 7 sites in China
- Sponsor
- Smith & Nephew Medical (Shanghai) Ltd
Spine Degeneration, Hip Arthritis
Evaluating the Efficacy of a Mobile Application in Postoperative Rehabilitation
This study aims to evaluate the effectiveness of a mobile application in improving postoperative rehabilitation outcomes among patients undergoing orthopedic surgery.
- Conditions
- Spine Degeneration, Hip Arthritis, Knee Osteoarthritis, Hip Fractures
- Trial name
- NCT06407427
- Testing
- App for in-bed conditioning exercises, Usual care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Osteoarthritis, Hip, Femur Head Necrosis
Clinical Outcomes of Primary Cementless Total Hip Arthroplasty Using the Collarless Actis Stem
This study looks at how well a hip replacement using the collarless Actis stem works over five years. Total hip replacement is a common operation for people whose hip joint has been damaged by arthritis, by loss of blood supply…
- Conditions
- Osteoarthritis, Hip, Femur Head Necrosis, Femoral Neck Fractures, Arthritis Rheumatoid
- Trial name
- NCT07828080
- Testing
- Collarless Actis femoral stem
- Where
- South Korea
- Volunteers
- 210 people
- Sponsor
- Seoul National University Bundang Hospital
Fracture Lower Leg, Diabetes
Extended Oral Antibiotic Prophylaxis in Diabetic Fracture Patients
The goal of this clinical trial is to learn if taking an antibiotic pill for 7 days after surgery reduces the risk of wound infection in adults with poorly controlled diabetes who have surgery to fix a broken bone in the leg…
- Conditions
- Fracture Lower Leg, Diabetes, Fracture Fixation, Internal
- Trial name
- NCT07561541
- Testing
- Cefadroxil 500 mg Capsules, Clindamycin, Bactrim DS
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Hip Fractures (ICD-10 72.01-72.2), Alzheimer s Disease
10-Year Survival After Acute Hip Fracture in Patients With Preclinical/Clinical Alzheimer Pathology
This study is a 10-year follow-up of a previously enrolled cohort of patients who underwent surgery for acute hip fracture with spinal anesthesia and had pre-fracture cognitive status assessed (Clinical Dementia Rating, CDR) and…
- Conditions
- Hip Fractures (ICD-10 72.01-72.2), Alzheimer s Disease, Dementia
- Trial name
- NCT07443566
- Where
- Sweden
- Volunteers
- 404 people
- Sponsor
- Bengt Nellgård
Hip Fractures
Radiologic and Clinical Outcomes of Augmentation in Fragility Intertrochanteric Hip Fracture Treatment
Randomized clinical trial to assess if the use of augmentation in the treatment of fragility intertrochanteric hip fractures improves radiologic and clinical outcomes in patients aged 65 years or older 1 year after surgery
- Trial name
- AFIF (NCT02631824)
- Testing
- open reduction and internal fixation, TFNA, Augmentation (Cement)
- Where
- 2 sites in Colombia
- Volunteers
- 90 people
- Sponsor
- Hospital Infantil Universitario de San Jose
Hip Fracture Surgeries, Geriatric Assessment
ASA or CFS for ICU Prediction in Geriatric Hip Fracture
The aim of this retrospective study is to compare the efficacy of the American Society of Anesthesiologists (ASA) physical status classification and the Clinical Frailty Scale (CFS) in predicting postoperative intensive care unit…
- Conditions
- Hip Fracture Surgeries, Geriatric Assessment, Frailty at Older Adults, Intensive Care
- Trial name
- NCT07522541
- Testing
- Routine Surgical and Anesthetic Mnagement.
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Ankle Fractures, Osteoarthritis, Ankle
Stability of Distal Tibiofibular Syndesmosis With or Without Fixation of Posterior Fragments in Bimalleolar Fractures
Background and Rationale: Injury to the tibiofibular syndesmosis in ankle fractures is a major prognostic factor for the development of post-traumatic osteoarthritis.
- Trial name
- SYNDESMOSE (NCT07755462)
- Testing
- Surgical management of bimalleolar ankle fractures with osteosynthesis of the posterior fragments., Surgical management of bimalleolar ankle fractures without osteosynthesis of the posterior fragments
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures), Postoperative Pain
FICB for Hip Fracture Pain in Elderly
Hip fracture is a common injury in elderly patients, often requiring surgical treatment. However, these patients frequently experience severe postoperative pain, which can delay mobility and recovery, and increase the risk of…
- Conditions
- Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures), Postoperative Pain, QoR-15, Fascia Iliaca Block
- Trial name
- FICB-PREP (NCT07762846)
- Testing
- Ultrasound-Guided Fascia Iliaca Compartment Block
- Where
- China
- Volunteers
- 144 people
- Sponsor
- RenJi Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.