Clinical trials: Fracture of Lower Limb
Ankle Fractures, Trauma Injury
Effect of Toradol on Post-operative Foot and Ankle Healing
The use of Toradol for pain control in surgical orthopedic cases is currently a topic of interest within the field. The proposed study is a prospective randomized study evaluating postoperative pain, opioid requirement…
- Trial name
- NCT03727048
- Testing
- Ketorolac, No ketorolac
- Volunteers
- 128 people
- Sponsor
- Rothman Institute Orthopaedics
Postoperative Pain
Evaluation of PENG Block in Terms of Block Time and Postoperative Pain
Hip fracture is a common orthopedic emergency in the elderly and causes significant morbidity and is associated with mortality. In most patients, surgical reduction and fixation is the definitive treatment.
- Trial name
- NCT06132308
- Testing
- PENG Block with 0.25% bupivacaine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Chronic Obstructive Pulmonary Disease, Proximal Femur Fracture
European Quality of Care Pathways Study on the Effect of Care Pathways on Interprofessional Teamwork (EQCP-TEAM)
Care pathways are complex interventions to support the interprofessional team in the redesign of their care process. This international cluster randomised trial will analyse the impact of the development and implementation of…
- Trial name
- EQCP-TEAM (NCT01435538)
- Testing
- Care pathway.
- Where
- Belgium
- Volunteers
- 984 people
- Sponsor
- Dr. Kris Vanhaecht
Intertrochanteric Fractures
Lateralization After IntraMedullary Nailing of InterTrochanteric Hip Fractures, Clinical and Radiographic Outcomes
Intertrochanteric fractures are commonly stabilized using an intramedullary nail with a lag screw that enters the lateral cortex of the femur.
- Trial name
- LIMIT (NCT05094791)
- Testing
- Telescoping Lag Screw, Standard lag Screw, Standard lag screw with addition of worm screw
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Prisma Health-Upstate
Trochanteric Fractures
Treatment of Unstable Trochanteric Fractures With the Proximal Femoral Nail - Antirotation (PFNA)-Asia
The primary objective of this prospective multicenter study is to assess any fracture fixation complication and revision rates during the clinical use of the Proximal Femoral Nail Antirotation Asia (PFNA Asia) for the treatment…
- Trial name
- NCT00873548
- Testing
- PFNA-Asia
- Where
- Japan
- Volunteers
- 245 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Fracture of Femur
Tranexamic Acid in Chinese Elderly Patients With Intertrochanteric Fracture RCT
Hip fracture posed a major challenge to the health care system, with the one-year mortality of hip fracture reported as being approximately 20%.
- Trial name
- NCT04290884
- Testing
- Tranexamic Acid
- Where
- Hong Kong
- Volunteers
- 120 people
- Sponsor
- The University of Hong Kong
Lower Extremity Periarticular Fractures
Early Standardized Weight Bearing Utilizing Immersion Therapy Following Periarticular Lower Extremity Fractures
The purpose of this prospective study is evaluate the effect of a standardized early weight bearing physical therapy protocol that utilizes immersion therapy on the clinical outcomes of lower extremity periarticular fractures.
- Trial name
- NCT01457326
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- University of Utah
Hip Fractures, Knee Fracture
Evaluation of Multidisciplinary Recovery After Surgery Program in Orthopedics and Traumatology
The aim of the recovery protocol is to reduce surgical trauma, postoperative pain, and complications, shorten hospital treatment and improve postoperative recovery.
- Conditions
- Hip Fractures, Knee Fracture, Hip Arthritis, Knee Arthritis
- Trial name
- NCT03822247
- Testing
- Multidisciplinary Recovery Program
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- Klinički Bolnički Centar Zagreb
Ankle Injuries, Fracture
Rest Easy: Is Bed Rest Really Necessary After Surgical Repair of an Ankle Fracture?
After a patient has fractured an ankle that then requires surgery, the recommendation is to remain in bed, with the operated leg elevated on pillows for 48 hours.
- Trial name
- NCT00690651
- Testing
- Early mobilization, Standard mobilization
- Where
- Australia
- Volunteers
- 104 people
- Sponsor
- The Alfred
Hip Fractures
Pre-op Femoral Nerve Block for Hip Fracture
Hip fractures (broken hips) are common in older people, particularly older women with fragile bones, and usually occur with a simple fall from a standing height.
- Trial name
- NCT02450045
- Testing
- Continuous femoral nerve block, 0.5% Ropivacaine/0.125% Bupivacaine local anesthetic mixture
- Where
- Canada
- Volunteers
- 73 people
- Sponsor
- University of Alberta
Hip Fracture, MACE
AI-Based Risk Factor Analysis and Prediction Model of MACE in Elderly Hip Fracture Patients Postoperatively
This is a multicenter ambispective observational cohort study led by Beijing Anzhen Hospital, Capital Medical University, with China-Japan Friendship Hospital serving as the external validation center.
- Conditions
- Hip Fracture, MACE, Elderly, Perioperative Complications
- Trial name
- NCT07709377
- Where
- 2 sites in China
- Volunteers
- 600 people
- Sponsor
- Beijing Anzhen Hospital
Tibial Plateau Fractures
Role of Multimodal Analgesia in Decreasing Perioperative Pain in Tibial Plateau Fractures
The investigators goal of the proposed research study is to determine the effectiveness of periarticular multimodal analgesia in the setting of tibial plateau fractures.
- Trial name
- NCT05037812
- Testing
- Saline injection, Multimodal injections
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Utah
Learning Curves and Outcomes of Simulation-based Training
Is Two-on-one Instruction in Virtual Reality Simulation-based Training of Operating Fractures of the Hip for Medical Students as Effective as One-on-one Instruction
The training of orthopedic surgeons has historically relied heavily on an apprenticeship model as the primary way of teaching the various procedures an aspiring surgeon needs to master.
- Trial name
- NCT06612619
- Testing
- Dyad instruction
- Where
- Denmark
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Lower Limb Fracture
Combined Lumbar and Sacral Branches Block Through the Ilio-Psoas Muscle Spaces for Analgesia of Lower Limb Surgeries
lumbosacral plexus block (LSPB) has been widely applied in orthopedics departments due to its advantages, including reduction in the application of opiates, decreasing the occurrence of acute pain, promoting early activation, and…
- Trial name
- NCT06019754
- Testing
- one point combined Lumbar and sacral plexus block
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Zagazig University
Hip Fractures, Lumbar Erector Spinae Plane Block
Comparative Assessment of Effectiveness and Safety of L-ESPB Versus Absence of Locoregional Block in Hip Surgery
Hip surgery accounts for a high percentage of both emergency and elective surgical procedures in hospitals. Regardless of surgery being prescribed to treat a fracture or coxarthrosis, patients are usually elderly with multiple…
- Trial name
- NCT06567522
- Testing
- Lumbar Erector Spinae Plane Block. L bupivacaína 0.25%
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Hospital Álvaro Cunqueiro
Intertrochanteric Fracture
PFN-A Augmentation for Intertrochanteric Femoral Fractures
This study evaluates the potential negative effect of cement augmentation in the femoral head on viability of the head. Half of the participants will have the standard intramedullary nail (PFN-A; Proximal Femoral Nail…
- Trial name
- NCT03000972
- Testing
- Cement augmentation, PFN-A Nail
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Uppsala University
Sarcopenia in Elderly, Sarcopenic Obesity
Comparative Analysis of Sarcopenia in Rehabilitation Outcomes Following Femoral Neck Fracture: a Study in Normal Weight and Obese Study Cohort
Impact of Obesity on Sarcopenia Prevalence and Severity in Elderly Adults Recovering from Femoral Neck Fractures: A Prospective Study Introduction Age-related muscle loss, or sarcopenia, which includes reductions in both muscle…
- Conditions
- Sarcopenia in Elderly, Sarcopenic Obesity, Frailty, Femoral Fractures
- Trial name
- NCT06705166
- Volunteers
- 300 people
- Sponsor
- Shmuel Harofeh Hospital, Geriatric Medical Center
Hip Fractures, Osteoporosis
A Study to Improve the Collaboration Between Primary and Secondary Health Care on the Treatment of Osteoporosis After a Hip Fracture.
This is a study to improve the collaboration between primary and secondary health care on the treatment of osteoporosis after a hip fracture.
- Conditions
- Hip Fractures, Osteoporosis, Zoledronic Acid, Ambulant Nurse
- Trial name
- NCT05904353
- Testing
- Ambulant nurse-assisted administration of zoledronic acid, Usual care
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- University Hospital, Akershus
Knee Fractures, Stiffness of Knee, Not Elsewhere Classified
Clinical Results After Judet Quadricepsplasty for Post-traumatic Knee Stiffness
The Post-traumatic Extension Contracture of the Knee (PECK) is a common complication following knee traumas. It is characterized by a restricted Range of Motion (ROM), pain, and discomfort in the affected knee.
- Trial name
- NCT06251765
- Testing
- Clinical scores, Range of Motion
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Ortopedico Rizzoli
Distal Femur Fractures
Dynamic Locking Screws 5.0 vs. Standard Locking Screws in Fracture of Distal Femur Treated With Locked Plate Fixation
The purpose of this study is to evaluate the performance of Dynamic Locking Screws (DLS) used to stabilize the shaft component of distal femur fractures in comparison to standard locking screws (SLS).
- Trial name
- NCT01693367
- Testing
- DLS 5.0 (Dynamic locking screws), SLS (Standard locking screw)
- Where
- 12 sites in United States, Austria and 2 more
- Volunteers
- 5 people
- Sponsor
- AO Innovation Translation Center
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