Clinical trials: Fracture of Lower Limb
Hip Fractures, Tibial Fractures
Go Fit Fast, Recovery Trajectory Using PROMIS®, Linking PROMIS®
Prospective data will be collected in approximately 3500 patients (700 per 5 injury groups). Patients will be followed up according to the standard (routine) for up to 1 year after the treatment.
- Conditions
- Hip Fractures, Tibial Fractures, Ankle Fractures, Humeral Fracture, Proximal
- Trial name
- NCT04113044
- Testing
- All treatments will remain the standard (routine) care procedures based on individual clinician's judgment and the patient characteristics.
- Where
- 15 sites in United States, Austria and 4 more
- Volunteers
- 1,500 people
- Sponsor
- AO Innovation Translation Center
Delirium - Postoperative, Hip Fractures (ICD-10 72.01-72.2)
Effect of Transcranial Direct Current Stimulation on Postoperative Delirium in Elderly Patients
To evaluate the efficacy of transcranial direct current stimulation (tDCS) in reducing the incidence of postoperative delirium (POD) in elderly patients undergoing hip fracture surgery.
- Trial name
- NCT06678529
- Testing
- active tDCS
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Huazhong University of Science and Technology
Femoral Neck Fractures
Retrieval Study and Histological Examination Of A Hip Femoral Components With Hydroxyapatite Coatings
Retrieval study and histological examination of BiMetric Femoral Components with hydroxyapatite coatings.
- Trial name
- NCT00757653
- Testing
- Hip stem with plasma sprayed porous Ti 6Al4V alloy + plasma sprayed HA, Hip stem with plasma spayed porous Titanium 6Al4V alloy + Bonemaster HA, Hip stem with Interloc Titanium surface + Bonemaster H.A
- Where
- United Kingdom
- Volunteers
- 57 people
- Sponsor
- Zimmer Biomet
Femur Fracture
Skeletal Versus Cutaneous Traction For Treatment of Femur Fractures
The purpose of this study is to determine whether there are any differences in skeletal or cutaneous traction for the treatment of femur fractures.
- Trial name
- NCT00916136
- Testing
- Femoral Traction
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Vanderbilt University Medical Center
Proximal (Subtrochanteric)Femoral Fractures, Distal Femoral Fractures
Evaluation of the Safety and Efficacy of a Guided Bone Regeneration Membrane for the Treatment of Femoral Fractures
Certain types of fractures require surgical intervention that may involve the use of bone grafts or bone graft substitutes. Many of the materials used as bone graft substitutes suffer from disadvantages such as soft tissue…
- Trial name
- NCT01687530
- Testing
- AMCA Bone Membrane.
- Where
- 2 sites in Israel
- Volunteers
- 48 people
- Sponsor
- RegeneCure, Ltd.
Femur Fracture
Natural History of Anterior Compartment Pressures of the Thigh Following Femur Fracture
This study is to determine the natural history of compartment pressures in the anterior thigh secondary to a fracture of the femoral shaft.
- Trial name
- NCT00919464
- Testing
- Pressure monitoring device, Compartmental fracture pressure monitoring, This small project is designed to be a non-randomized, investigational prospective trial of compartment pressures in the thigh following femoral fracture
- Volunteers
- 7 people
- Sponsor
- CAMC Health System
Embolism, Femoral Fractures
Effect of a Novel Reamer-Irrigator-Aspirator on the Incidence of Fat Embolism
The purpose of this study is to determine the effect on the incidence of fat emboli when using a Reamer-Irrigator Aspirator during reamed IM nail fixation of femoral shaft fractures
- Trial name
- RIA (NCT00509171)
- Testing
- Reamer Irrigator Aspirator
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Fracture of Neck of Femur, Resumption of Walking
Prognostic Impact of Neopterin on Resumption of Walking After a Fracture of the Upper Neck of the Femur in the Elderly
Society faces a major challenge with the management of the health and socio-economic burden caused by acute physical stress in the older population (>75 years).
- Trial name
- MAMI (NCT05233072)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fracture of Hip, Osteoarthritis, Hip
Mechanical Ventilation Based on Driving Pressure in Lateral Position
Previous studies showed that, best lung protective strategies of ventilation parameters are based on driving pressure in damaged lungs.
- Conditions
- Fracture of Hip, Osteoarthritis, Hip, Congenital Hip Deformity
- Trial name
- NCT04455789
- Testing
- routine lung protective, conventional mechanical ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Akdeniz University
Hip Fractures, Anesthesia Local
Shamrock Versus Lumbar Ultrasound Trident - Ultrasound Guided Block of the Lumbar Plexus
The main objective of the trial is to complete a double-blinded randomized controlled trial of a lumbar plexus block with the Shamrock technique versus the Lumbar Ultrasound Trident technique by estimating the time of performance…
- Conditions
- Hip Fractures, Anesthesia Local, Pain, Postoperative
- Trial name
- NCT02255591
- Testing
- Lidocaine-adrenaline added gadolinium.
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Knee Injuries
Trial Comparing BST-CarGel and Microfracture in Repair of Articular Cartilage Lesions in the Knee
This study will investigate whether the treatment of damaged cartilage in the knee with BST-CarGel will increase the amount and quality of cartilage repair tissue when compared with microfracture alone.
- Trial name
- NCT00314236
- Testing
- BST-CarGel with Microfracture, Microfracture without BST-CarGel
- Where
- 18 sites in Canada, South Korea and 1 more
- Volunteers
- 80 people
- Sponsor
- Piramal Healthcare Canada Ltd
Hip Fracture Surgery, Postoperative Pain Management
Comparison of Sacral Erector Spinae Plane Block and Supra-Inguinal Fascia Iliaca Block for Analgesia After Hip Fracture Surgery
This study compares the postoperative analgesic effectiveness of Sacral Erector Spinae Plane Block (SESPB) and Supra-Inguinal Fascia Iliaca Block (SIFIB) in patients undergoing hip fracture surgery.
- Conditions
- Hip Fracture Surgery, Postoperative Pain Management, Regional Anesthesia, Elderly Patients
- Trial name
- NCT07081867
- Testing
- Supra-inguinal Fascia Iliaca Block (SIFIB), Sacral Erector Spinae Plane Block (SESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Hip Fracture (First Incidence of)
Diet and Hip Fracture Risk in the United Kingdom Women's Cohort
Hip fracture is a common serious injury in older women that reduces quality of life and can lead to premature death. In the United Kingdom, hip fractures are estimated to account for 1.5 million hospital bed days used per year…
- Trial name
- NCT05081466
- Testing
- Dietary pattern, Fruit and vegetable intake, Meat intake
- Where
- United Kingdom
- Volunteers
- 35,372 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Hip Injuries, Hip Fractures
Is the Rate of Early Mobilisation in Hip Fracture Patients Using Alfentanil Better Than Standard Opioid Analgesia?
Hip fracture injuries are linked with increased morbidity, frailty, and mortality risk. Studies have shown that in hip fracture surgery, early mobilisation confers better pain control, 30-day complication and mortality rates and…
- Conditions
- Hip Injuries, Hip Fractures, Pain, Post Operative Pain
- Trial name
- REHAB (NCT06212622)
- Testing
- Alfentanil, Oxycodone
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- NHS Lothian
Femur Fracture, Erector Spinae
Comparison of Erector Spina Plane Block and Lumbar Plexus Block in Femoral Fracture Surgery
The aim is to clinical trials compare the lumbar plexus block method with the erector spinae plan block method in terms of analgesic efficacy and possible complications. İn patients for femur fracture surgery.
- Conditions
- Femur Fracture, Erector Spinae, Lumbar Plexus, Ultrasound Guide
- Trial name
- NCT05817916
- Testing
- ESP block, LP block
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Sakarya University
Femoral Neck Fractures, Geriatric Hip Fracture
Efficacy of Oral Nutritional Supplement in Femoral Neck Fracture Patients Undergoing Hip Arthroplasty
This study aim to compare the efficacy of oral nutritional supplementation (ONS) in femoral neck fracture patients undergoing hip arthroplasty compared with placebo.
- Conditions
- Femoral Neck Fractures, Geriatric Hip Fracture, Hip Fracture, Post Surgery Recovery, Muscle Resilience
- Trial name
- NCT07780006
- Testing
- Oral nutritional supplementation
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Thammasat University
Delirium - Postoperative, Delirium Prevention
Dexmedetomidine for Prevention of Delirium After Hip Fracture Surgery
Postoperative delirium is common after hip fracture surgery and is associated with delayed recovery and serious postoperative complications.
- Conditions
- Delirium - Postoperative, Delirium Prevention, Dexmedetomidine, Dexmedetomidine Infusion
- Trial name
- DEXLIR (NCT07867899)
- Where
- Denmark
- Volunteers
- 242 people
- Sponsor
- Peter Gaarsdal Uhrbrand
Osteoarthritis, Hip, Fracture of Hip
Post Market Clinical Follow-Up of the Zimmer Stafit Acetabular System
This study is a Post Market Clinical Follow up study to fulfil the post market surveillance obligations according to Medical Device Directive and European Medical Device Vigilance System (MEDDEV) 2.12-2.
- Conditions
- Osteoarthritis, Hip, Fracture of Hip, Avascular Necrosis of Hip, Dislocated Hip
- Trial name
- NCT04079114
- Testing
- Patients who received the Stafit Acetabular System
- Volunteers
- 166 people
- Sponsor
- Zimmer Biomet
Pain, Postoperative, Ankle Fracture Surgery
Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery
Addictive full-agonist opioids, like oxycodone and hydrocodone, are often used to treat pain after surgery. However, these full-agonist opioids can be very addictive.
- Conditions
- Pain, Postoperative, Ankle Fracture Surgery, Opioid Use Disorder, Opioid Dependence
- Trial name
- BAFA (NCT06949826)
- Testing
- Buprenorphine Transdermal System
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Jenna-Leigh Wilson
Femoral Neck Fracture
Efficacy and Safety of Topical Tranexamic Acid (TXA) Administration Cementless Bipolar Hemiarthroplasty for Femoral Neck Fracture - a Randomized Controlled Trial
The goal of this Randomized controlled trial is to evaluate in household ambulatory, elderly patients sustaining femoral neck fracture who are subjected to be treat with cementless bipolar hemiarthroplasty.
- Trial name
- TXA (NCT06289478)
- Testing
- Retrograde Intraarticular Injection via Drain Tube, Topical Soaking of Tranexamic Acid
- Where
- 2 sites in Thailand
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- King Chulalongkorn Memorial Hospital
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