Clinical trials: Fracture of Lower Limb
Morphological Analysis and Classification, Posterior Malleolar Fractures
Morphological Analysis and Classification of Posterior Malleolar Fractures Based on CT Scans
The study was to propose a classification system of posterior malleolar fractures by fracture lines with the use of CT scans, including 3D CT reconstruction, which can better understand morphological characteristics, analyze the…
- Conditions
- Morphological Analysis and Classification, Posterior Malleolar Fractures, CT Scans
- Trial name
- NCT05159258
- Volunteers
- 128 people
- Sponsor
- Peking University People's Hospital
Fall Injury, Hip Fractures
Does the New Fall- and Fracture Prevention Initiative in Oslo Have Effect?
The goal of this controlled before and after study is to evaluate a new patient pathway for patients 65 years and older who have suffered a fall injury.
- Trial name
- NCT05680714
- Testing
- Implement coordination of care with multifactorial falls- and fracture risk assessment and tailored intervention
- Volunteers
- 121,000 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Cognitive Decline, Delirium
CITADEL: Effectiveness of CITicoline in Preventing Cognitive Decline After DELirium
The aim of this study is to assess whether citicoline (TRAUSAN), a neuroprotective agent involved in membrane phospholipid synthesis and neurotransmission, can prevent or attenuate cognitive decline in older adults who develop…
- Trial name
- CITADEL (NCT07804498)
- Testing
- Citicoline
- Where
- Italy
- Volunteers
- 122 people
- Sponsor
- University of Milano Bicocca
Osteomyelitis, Bone Infection
Clinical Effectiveness of S53P4 Bioactive Glass in Treatment of Long-bone Chronic Osteomyelitis
This clinical trial studies the clinical effectiveness of S53P4 bioactive glass (BAG) as a bacterial growth inhibiting bone graft substitute in a one-stage or two-stage surgical procedure for treatment of chronic long bone…
- Conditions
- Osteomyelitis, Bone Infection, Non-Union Fracture, Bone Infection of Lower Leg
- Trial name
- NCT04945434
- Testing
- S53P4 bioactive glass (BonAlive)
- Volunteers
- 78 people
- Sponsor
- Academisch Ziekenhuis Maastricht
Hip Fractures, Elderly Patients
Comparison of Phenylephrine and Ephedrine in the Treatment of Hemodynamic Disorders After Spinal Anesthesia in the Elderly
Spinal anesthesia is often used for lower limb surgery in elderly. Hypotension is a side effect of spinal block. In this study, intravenous ephedrine and phenylephrine will be compared with each other to prevent spinal…
- Conditions
- Hip Fractures, Elderly Patients, Spinal Anesthesia, Lower Limb Surgery
- Trial name
- HypoGer (NCT03858465)
- Testing
- Ephedrine, Phenylephrine
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Warsaw
Hip Fractures
Blood Loss After Early TXA in Hip Fractures.
Our present study aims to initiate TXA administration immediately upon diagnosis of hip fracture in the Emergency Department. This will be a single blind randomized controlled trial comparing early administration of TXA in the ED…
- Trial name
- NCT04488367
- Testing
- Tranexamic acid, Normal Saline
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Community Memorial Health System
Femur Fracture
Analgesic Effect of Paracetamol in Patients With Femur Fracture: is Intravenous Better Than Oral?
The purpose of this study is to monitor severe pain for femur fracture after treatment with paracetamol IV or OR.
- Trial name
- NCT05025228
- Testing
- Paracetamol
- Where
- Italy
- Volunteers
- 170 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hip Fractures
Cemented Hemiarthroplasty Versus Uncemented Furlong Hemiarthroplasty
In England each year over 9,000 people fracture their hip. Most of these are elderly females with the fracture occurring after a fall.
- Trial name
- NCT02998034
- Testing
- Uncemented Furlong Hemiarthroplasty, Cemented tapered stem hemiarthroplasty
- Where
- United Kingdom
- Volunteers
- 400 people
- Sponsor
- Peterborough and Stamford Hospitals NHS Foundation Trust
Periprosthetic Fracture of the Upper or Lower Limb, Peri-implant Fracture of the Upper or Lower Limb
Peri-Implant and Peri-Prosthetic Fractures: Epidemiology, Morbidity, Mortality, Treatment and Outcome Analysis
This study supports Spanish data collection and analysis on Periprosthetic and Peri-implant fractures of the upper and lower limb. Treatment and clinical management of this fractures are complex and goes along with complications.
- Conditions
- Periprosthetic Fracture of the Upper or Lower Limb, Peri-implant Fracture of the Upper or Lower Limb, Periprosthetic Fractures, Peri-implant Fracture
- Trial name
- PIPPAS (NCT04663893)
- Where
- 7 sites in Spain
- Volunteers
- 2,500 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Hip Fractures
Effect of a Robotic Platform for Hip Fracture Rehab
Hip fracture is one of the most common traumas associated with falls in the elderly, severely affecting the patient's mobility and independence.
- Trial name
- NCT05079555
- Testing
- Robotic rehab
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Werium Assistive Solutions
Femoral Neck Fracture, Hip Fracture
External Validity of a Randomized Trial in Patients With a Femoral Neck Fracture
The aim of this study is to evaluate the external validity of a randomized controlled trial comparing choice of hip arthroplasty for elderly patients (>80 years) with a displaced femoral neck fracture.
- Trial name
- EXVAL (NCT02362971)
- Where
- Sweden
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Danderyd Hospital
Hip Fracture
Tranexamic Acid in HIp Fracture Surgery (THIF Study)
The purpose of this study is to assess the efficacy of tranexamic acid in hip fracture surgery on the reduction of allogeneic red blood cell transfusion.
- Trial name
- THIF (NCT00327106)
- Testing
- Tranexamic acid (Exacyl)
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Tibial Fractures, Fracture Infection
Zimmer® Natural Nail® (ZNN) Bactiguard Tibia Post-Market Clinical Follow-up Study
Primary objective of this study is to compare fracture related infection (FRI) rates of ZNN Bactiguard Tibia to conventional uncoated titanium-alloy nails 12 months after tibia fracture fixation.
- Trial name
- NCT05022485
- Testing
- ZNN Bactiguard tibia
- Where
- 16 sites in Austria, France and 6 more
- Volunteers
- 500 people
- Sponsor
- Zimmer Biomet
Femur Fracture
Randomized, Prospective Comparison of Two Femoral Reaming Systems
The purpose of this study is to compare the quantity of fat that is released into the venous system (blood) by reaming the femoral canal during intramedullary nailing of the femur using two different reaming systems.
- Trial name
- RIA (NCT00594438)
- Testing
- Synthes Reamer-Irrigator-Aspirator (RIA), Zimmer Sentinel Reamer
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Ankle Fracture
Triage Nurse Initiated Radiographs According to OAR
The purpose of the study is to help doctors in emergency departments know whether triage nurse initiated radiographs, in accordance to the Ottawa ankle rule, before emergency physician assessment will shorten emergency patients'…
- Trial name
- NCT01654393
- Testing
- Triage nurses applying the OAR
- Where
- Canada
- Volunteers
- 142 people
- Sponsor
- Vancouver Coastal Health
Humerus Fracture, Femur Fracture
Evaluation of Handling and Possible Complications Related to the Newly Developed Angular Stable Locking System (ASLS)
In many cases, the existing locking bolts and screws in intramedullary nails do not provide sufficient stability. Due to the play between screw and nail, the reduction can be lost and the instability can result in malunions…
- Conditions
- Humerus Fracture, Femur Fracture, Tibia Fracture
- Trial name
- ASLS-Pre (NCT00793637)
- Where
- 4 sites in Austria, Germany
- Volunteers
- 30 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Bone Marrow, Femoral Neck Fractures
Bone Marrow Injection in Fracture of Femoral Neck
Objectives: Primary objective : To investigate the predisposing factors for femoral neck fractures, including age, sex, and associated comorbidities.
- Trial name
- NCT07808294
- Testing
- Anatomical reduction and fixation with bone marrow injection, Anatomical reduction with Fixation
- Where
- Syria
- Volunteers
- 32 people
- Sponsor
- Yaser Alkanash
Femoral Fracture
A Study to Verify if the Surgery for the Proximal Femur Fracture Can be Improved With the Help of a Navigation System
The ADAPT system is a software that calculate a virtual 3D reconstruction of the femoral head without additional radiation. It automatically detects the used implant and its position relative to the femoral head, helping the…
- Trial name
- NCT04494672
- Testing
- Intramedullary nailing with ADAPT system, Intramedullary nailing without ADAPT system
- Where
- Switzerland
- Volunteers
- 96 people
- Sponsor
- Christian Candrian
Ankle and Hindfoot Arthrodesis
Long-term Safety and Effectiveness of AUGMENT® Injectable Bone Graft Compared to Autologous Bone Graft
The objective of this long-term study is to evaluate the long-term effectiveness and safety of AUGMENT® Injectable Bone Graft vs. autologous bone graft.
- Trial name
- NCT03998137
- Testing
- AUGMENT® Injectable Bone Graft, Standard of Care
- Volunteers
- 94 people
- Sponsor
- BioMimetic Therapeutics
Pelvic Trauma, Pelvic Fracture
A Snapshot Audit of Traumatic Pelvic Ring Injuries
Multicenter, snapshot cohort studies or audits have the ability to gather large patient numbers in short time periods from many healthcare systems with different resources or practices of care concerning one specific surgical…
- Conditions
- Pelvic Trauma, Pelvic Fracture, Fragility Fractures of the Pelvis (FFP)
- Trial name
- NCT06540339
- Testing
- Snapshot-audit studies do not necessitate any intervention in the defined cohorts.
- Volunteers
- 500 people
- Sponsor
- University Hospital, Aachen
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