Clinical trials: Fractures, Bone, open to volunteers
Hand Injuries, Finger Fracture
Percutaneous Pinning vs Orthosis and Early Mobilization
This study aims at investigating if splinting and early mobilization is a better method, regarding range of motion, for treating fractures of the base phalanx of the fingers compared to surgery with pinning.
- Trial name
- POEM (NCT04561661)
- Testing
- Percutaneous pinning, Conservative treatment
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Karolinska Institutet
Tibial Shaft Fracture, Intramedullary Nail
RCT - Suprapatellar Approach Versus Lateral Parapatellar Approach in Tibial Shaft Fracture
This study aims to compare 2 surgical techniques for tibial shaft nailing (suprapatellar approach vs extra-articular lateral parapatellar approach). following peri-operative and postoperative outcomes
- Trial name
- ELPP (NCT07657559)
- Testing
- suprapatellar approach, extra-articular lateral parapatellar approach
- Volunteers
- 40 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Femoral Fracture, Fragility Fracture
Essential Amino Acid Supplementation for Femoral Fragility Fractures
This trial will evaluate the impact of 4 weeks of postoperative essential amino acid (EAA)-based supplementation on muscle morphology after femoral fragility fracture.
- Conditions
- Femoral Fracture, Fragility Fracture, Muscle Atrophy
- Trial name
- NCT06050668
- Testing
- Essential Amino Acid Supplementation
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Michael C Willey
Hip Fractures, Venous Thromboembolism (VTE)
Delivery and Implementation of a Randomised Crossover Trial on Thrombosis
What is the Study About? The DIRECT study (Delivery and Implementation of a Randomised Crossover Trial on Thrombosis) is a large research project investigating the best way to prevent blood clots (thrombosis) in people who break…
- Trial name
- DIRECT (NCT06937372)
- Testing
- Patients in hospitals allocated to this arm will receive aspirin as their routine thromboprophylaxis after surgery., Low molecular weight heparin (LMWH)
- Where
- United Kingdom
- Volunteers
- 21,194 people
- Sponsor
- Queen Mary University of London
Wrist Fractures, Distal Radius Fractures
Unilateral Training of the Uninjured Limb on Clinical Outcomes in Patients with Surgically Treated Radius Fracture
The objective will be to determine the effectiveness of adding unilateral upper limb postoperative training to standard rehabilitation compared to standard rehabilitation on maximum grip strength and manual dexterity in patients…
- Trial name
- NCT06698367
- Testing
- Standard rehabilitation, Unilateral high-intensity strength exercise, Unilateral mobility exercises
- Where
- Chile
- Volunteers
- 52 people
- Sponsor
- Universidad Catolica de Temuco
Body Balnace and Calcaneal Fractures
Calcaneal Angles And Postoperative Body Balance Following Internal Fixation
The goal of this observational cross sectionl study is to explore the correlation between Böhler angle and dynamic postural stability indices after calcaneal internal fixation.
- Trial name
- POIF (NCT07589192)
- Testing
- Biodex balance system
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Zygomaticomaxillary Complex Fracture, Zygomatic Fractures
BoneTape Feasibility Trial
This study aims to evaluate the safety, effectiveness, and usability of BoneTape, an innovative medical device designed to fix facial bone fractures, specifically in the zygomaticomaxillary (midface) region.
- Conditions
- Zygomaticomaxillary Complex Fracture, Zygomatic Fractures, Zygoma Fracture
- Trial name
- NCT06600854
- Testing
- BoneTape
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Cohesys Inc.
Proximal Humeral Fractures
Hip-allograft In Proximal Humerus Fractures Versus Plate Implantation Alone: a Randomized Controlled Trial
Proximal humerus fractures (PHFs) are common osteoporotic fractures in adults and the elderly, leading to significant disability and reduced quality of life.
- Trial name
- HIPPI (NCT07538700)
- Testing
- Locking plate fixation with femoral allograft augmentation
- Where
- Netherlands
- Volunteers
- 56 people
- Sponsor
- Tergooi Medical Center
Zygoma Fracture
Outcomes of Zygomatic Fractures: Cross- Sectional Study
Rationale: Facial trauma is a significant event for patients, often resulting in physical and psychological consequences. Fractures in the zygomatic bone area are common due to its unique shape and positioning in the face…
- Trial name
- ZY-PROM (NCT06476340)
- Testing
- No intervention
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Acetabular Fracture
Weight-bearing of Surgically Treated Acetabular Fractures.
The purpose of this study is to determine whether patients with operatively treated acetabular fractures benefit from early weight-bearing as tolerated.
- Trial name
- NCT04724811
- Testing
- Open reduction and internal fixation (ORIF)
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital District of Helsinki and Uusimaa
Trauma (Including Fractures)
Stress in Trauma Patients in Triage Categories 3-5
The aim of this study is to better understand what causes patients the most concern immediately after an injury. We would like to find out how stressed patients are and whether the main causes of stress are pain, fear regarding…
- Trial name
- NCT07811830
- Testing
- Questionnaire and Physical Exam
- Where
- Croatia
- Volunteers
- 300 people
- Sponsor
- Gabriela Katharina Pomper
Ankle Fractures
Hardware Removal After ORIF of Ankle Fractures
Ankle fractures account for 10 % of fractures in the adult population. A part of patients (40%) is treated surgically. After healing of the fractures, about one year after the operation, a surgery is often performed to remove the…
- Trial name
- NCT05798741
- Testing
- Hardware removal
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Hôpital Fribourgeois
Fracture of Neck of Femur
Medial Enhancement Technique for the Treatment of Old Femoral Neck Fractures
A prospective, multi-center, randomized controlled study was conducted to validate the safety and effectiveness of employing the medial augmentation technique (incorporating the dynamic condylar screw and medial support plate)…
- Trial name
- NCT06713031
- Testing
- cannulated compression screws + iliac bone graft, DCS + medial support plate + iliac bone graft
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Chinese PLA General Hospital
Pelvic Bone Injury, Pelvis Injury
RELIEVED (REgionaL anesthesIa PElVic fracturEs stuDy) Study. Regional Anesthesia (RA) Techniques for Pain Management in Pelvic Fractures: A Prospective, Monocentric, Pilot Cohort Study.
The goal of this observational clinical trial is to assess the impact of Regional Anesthesia (RA) techniques with the strongest anatomical and scientific support in controlling acute post-operative pain in pelvic/acetabular…
- Conditions
- Pelvic Bone Injury, Pelvis Injury, Acetabular Fractures, Acetabular Surgery
- Trial name
- RELIEVED (NCT07072286)
- Testing
- Regional Anesthesia, Multimodal analgesia
- Where
- Italy
- Volunteers
- 177 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Colles' Fracture
Comparison of Functional Outcomes of Closed Reduction With Cast Versus Closed Reduction With K-Wire Fixation in Colles' Fracture
Colles' fracture is a common distal radius injury, often managed with closed reduction and Plaster of Paris (POP) casting. However, loss of alignment may occur with casting alone.
- Trial name
- NCT07281469
- Testing
- Closed reduction and fracture manipulation and plaster of Paris application in group A, closed reduction and Percutaneous K-wire fixation and plaster of application is applied in group B
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Khawaja Muhammad Safdar Medical College
Mandibular Fractures
Custom-Made Titanium Plates Versus Custom-Made Polyether Ether Ketone (PEEK) Plates
Mandibular fractures represent a significant portion of maxillofacial trauma, primarily resulting from motor vehicle accidents, interpersonal violence, and sports-related injuries.
- Trial name
- NCT07850570
- Testing
- Custom-Made Titanium Plate, Custom-Made PEEK Plate
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Mansoura University
Distal Radius Fracture Fixation
Same Day Discharge Vs. Hospitalization for Operative Fixation of Distal Radius Fractures
The goal of this clinical trial is to examine the results for same-day discharge after distal radius operative fixation in adult pupolation.
- Trial name
- NCT07276334
- Testing
- early release from hospital, Day after surgery release
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Assaf-Harofeh Medical Center
Orbital Fractures, Unilateral
Comparing Pre-adaptation of In-stock Mesh Over In-house 3D Patient Specific Model to Reconstruct Unilateral Primary Orbital Fracture With and Without Intraoperative Navigation vs Conventional Intraoperative Free-hand Mesh Bending
The investigators study the accuracy of repairing unilateral primary orbital fractures using a new technique, using 3D printed patient specific model to preoperative adapting of the readily available in sock titanium mesh, the…
- Conditions
- Orbital Fractures, Unilateral, Recent
- Trial name
- NCT07882121
- Testing
- 3D printed patient specific model, Conventional, Brainlab navigation system
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Tibial Fracture
Assessment of the Verus Frame in Tibial Intramedullary Nailing
This prospective, single-arm Post-Market Clinical Follow-Up (PMCF) study, utilizing a registry-based control group, will assess the Verus frame's effectiveness in achieving precise tibial rotation and alignment during…
- Trial name
- NCT07362121
- Testing
- Verus frame to stabilize tibia
- Where
- Finland
- Volunteers
- 25 people
- Sponsor
- Hemitec Finland Oy
Glenohumeral Osteoarthritis, Proximal Humerus Fracture
Post-Market Clinical Follow-Up (PMCF) Study Evaluating the Safety and Efficacy of Tıpmed™ Shoulder Prosthesis System
This study is designed as a prospective, multicenter, observational post-market clinical follow-up (PMCF) study to evaluate the safety and effectiveness of the Tipmed™ Shoulder Prosthesis System at 12 months postoperatively.
- Conditions
- Glenohumeral Osteoarthritis, Proximal Humerus Fracture, Rotator Cuff Arthropathy, Rheumatoid Arthritis
- Trial name
- NCT07678034
- Testing
- Tipmed™ Reverse Shoulder Prosthesis System, Tipmed™ Shoulder Prosthesis System (Hemiarthroplasty Configuration)
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- TIPMED Medical Device Manufacturing Ltd. Co.