Clinical trials: Fractures, Spinal
Osteoporosis, Postmenopausal, Back Pain
Effect of Teriparatide Compared to Risedronate on Back Pain in Women With a Spine Fracture Caused by Osteoporosis
The purpose of the study is to determine if daily teriparatide reduces back pain more effectively than weekly risedronate in women with osteoporosis who have chronic back pain due to a spinal bone fracture.
- Conditions
- Osteoporosis, Postmenopausal, Back Pain, Spinal Fracture
- Trial name
- NCT00343252
- Testing
- teriparatide, risedronate
- Where
- 72 sites in United States, Argentina and 11 more
- Volunteers
- 712 people
- Sponsor
- Eli Lilly and Company
Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery
The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury
In this prospective, randomized, single-blind study, we aim to compare the effects of general anesthesia and spinal anesthesia on postoperative myocardial injury in elderly patients undergoing hip surgery.
- Conditions
- Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery, Anesthesia, General, Anesthesia, Spinal
- Trial name
- NCT06343259
- Testing
- General Anesthesia, Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Femoral Fracture, Cognition Disorders
Influence of Intrathecal Dexamethasone Administration for Proximal Femoral Fractures
Spinal anesthesia blocks acute pain in older patients with femur fracture. Delirium is a common complication seen after femur fracture, affecting approximately 10-16% of patients.
- Conditions
- Femoral Fracture, Cognition Disorders, Cortisol; Hypersecretion
- Trial name
- NCT03856502
- Testing
- 8 mg of dexamethasone, 12,5 mg of 0,5 % of levobupivacaine
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- General Hospital Sveti Duh
Preoperative Anxiety, Cesarean Delivery
Video Versus Verbal Preoperative Education in Elective Cesarean Delivery
This prospective randomized controlled trial aims to evaluate the effects of verbal and video-based preoperative education on anxiety levels and serum cortisol response in women scheduled for elective cesarean delivery under…
- Conditions
- Preoperative Anxiety, Cesarean Delivery, Stress Response
- Trial name
- VIDEO-CS (NCT07647601)
- Testing
- Video-Based Preoperative Education, Verbal Preoperative Education
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Osteoporotic Fracture of Vertebra
Safety and Efficacy of the ISS Sleeve Augmentation Technique in the Treatment of Thoracolumbar Osteopenic Fractures
Implant anchorage is difficult in patient with osteoporotic bone. To improve the implant bone interface, the ISS stabilization system has been developed.
- Trial name
- NCT04495439
- Testing
- Augmentation with the ISS Study System, Augmentation with PMMA
- Where
- Austria
- Volunteers
- 2 people
- Sponsor
- Nexilis AG
Osteoporosis
Trial to Evaluate Tibolone in the Treatment of Osteoporosis (P06468)
Tibolone 1.25 mg is an effective treatment for the prevention of osteoporosis and is expected to be effective in preventing fractures in osteoporotic women.
- Trial name
- LIFT (NCT00519857)
- Testing
- Tibolone
- Volunteers
- 4,534 people
- Sponsor
- Organon and Co
Hip Fracture Surgeries
Comparative Study Between Pericapsular Nerve Group Block (PENG) And Pericapsular Nerve Group (PENG) Block Combined With Lateral Femoral Cutaneous Nerve (LFCN) Block for Positioning Analgesia Prior to Spinal Anesthesia in Hip Fracture Patients
To evaluate and compare the effectiveness of the Pericapsular Nerve Group (PENG) block alone versus the PENG block combined with the Lateral Femoral Cutaneous Nerve (LFCN) block in providing adequate analgesia for patient…
- Trial name
- NCT07687290
- Testing
- PENG Block, LCFN block, bupivacaine 0.25%.
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Ain Shams University
Spinal Fractures
Randomized Trial With an Observational Component of Non-operative Versus Operative Treatment for AO Type A3 Fractures
The purpose of this study is to compare surgery plus bracing versus bracing alone. Both groups are considered standard of care treatments. The goal of this study is to determine which group is a better treatment.
- Trial name
- NCT02179697
- Testing
- Patient's Choice, Surgery + Bracing vs. Bracing Alone
- Where
- United States
- Sponsor
- H Francis Farhadi
Osteoporotic Vertebral Fracture, Between T5 and L5
Comparison of Balloon Kyphoplasty, Vertebroplasty and Conservative Management in Acute Osteoporotic Vertebral Fractures
This study aims to compare three treatments in recent (less than 6 week duration) non-traumatic ( usually osteoporotic) vertebral fractures.
- Conditions
- Osteoporotic Vertebral Fracture, Between T5 and L5, of Less Than 6 Weeks Duration
- Trial name
- OSTEO-6 (NCT00749060)
- Testing
- conventional treatment, kyphoplasty with balloons, vertebroplasty
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hip Fractures
Haemodynamic Effects of Low-dose Spinal Anaesthesia for Hip Fracture Surgery.
Approximately 65, 000 hip fractures occur in the United Kingdom (UK) each year, and more than 99% are repaired by surgery. Roughly half of patients receive spinal anaesthesia, where a small amount (usually less than half a…
- Trial name
- NCT05799300
- Testing
- Intrathecal anaesthesia
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Royal Sussex County Hospital
Acetabular Fractures, Hip Replacement
Multicenter Retrospective Evaluation of the Surgical Management of Spinal Growth Dystrophy
Spinal growth dystrophy (CRD), also called Scheuermann's disease, corresponding to impaired vertebral structure occurring in children and adolescents with involvement of the growth cartilage causing impaired growth and kyphosis.
- Trial name
- DRC (NCT02904681)
- Testing
- No intervention. Observational and descriptive study
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Osteoporotic Fracture of Vertebra
Percutaneous Vertebral-disc Plasty for Thoracolumbar Very Severe Osteoporotic Vertebral Compression Fractures
Purpose: To compare the clinical outcomes and radiological parameters of patients undergoing percutaneous vertebroplasty (PVP) versus those undergoing percutaneous vertebral-disc plasty (PVDP) for back pain, segmental…
- Trial name
- NCT05519332
- Testing
- percutaneous vertebral-disc plasty
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jiawei Jiang
Spinal Muscular Atrophy Type 3, Ambulatory Spinal Muscular Atrophy
Gait and Bone Health in SMA
The objective of this study is to understand how spatiotemporal and kinetic gait parameters are associated with bone health in pwSMA who are receiving DMT.
- Trial name
- NCT07400198
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Jacqueline Montes
Kyphosis, Vertebral Fracture
A Study of Effects of Age and Hyperkyphosis on Spine Motion and Loading
We are studying how spine movement changes with age, and when people have vertebral fractures (cracks in the bones of the spine) or hyperkyphosis (a forward stooped posture).
- Trial name
- NCT03008902
- Testing
- Near-infrared passive motion capture recording
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Postoperative Pain, Spine Deformity
Intraoperative Placement of Superficial Erector Spinae Plane Block; A New Approach in Spine Surgery
Major spine surgery causes severe postoperative pain. The primary objective of this randomized controlled study is to compare the effect of ultrasound (US)-guided superficial erector spinae plane (ESP) block on 48-hour…
- Conditions
- Postoperative Pain, Spine Deformity, Spine Injury, Spine Fracture
- Trial name
- NCT05244031
- Testing
- superficial erector spina plane block, Standard (opioid-based) analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Osteo Arthritis Shoulders, Osteonecrosis
Exactech Shoulder Post Market Clinical Follow-up Study
The objective of this study is to collect and evaluate long-term clinical and radiographic outcomes data in order to better understand the safety and performance of the shoulder arthroplasty over time.
- Conditions
- Osteo Arthritis Shoulders, Osteonecrosis, Rotator Cuff Tears, Rotator Cuff Tear Arthropathy
- Trial name
- NCT05603728
- Where
- 40 sites in United States, Canada and 4 more
- Volunteers
- 20,000 people
- Sponsor
- Exactech
Ankylosing Spondylitis (AS), Spine Fracture
A Retrospective Cohort Study About Surgical Efficacy for Lower Cervical Fractures in Ankylosing Spondylitis
The purpose of this retrospective cohort study was to observe and compare the efficacy of anterior cervical long segment fixation, posterior long segment fixation, and combined anterior and posterior fixation for the treatment of…
- Trial name
- NCT06873074
- Testing
- anterior long segment cervical fixation, posterior long segment cervical fixation, combined anterior and posterior fixation
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Zhou Fang
Osteoporosis, Postmenopausal
Impact of Oral Ibandronate 150 mg Monthly on Structural Properties of Bone in Postmenopausal Osteoporosis (SPIMOS-3D)
Efficacy: To investigate changes of structural bone properties in vivo using 3DpQCT ("Xtreme" CT, Scanco) in monthly oral ibandronate therapy for women with postmenopausal osteoporosis.
- Trial name
- NCT00271713
- Testing
- ibandronate, calcium and vitamin D
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Charite University, Berlin, Germany
Regional Anaesthesia
Comparison Between Ultrasound Guided Femoral 3 in 1 Block Versus Blind Fascia Iliaca Block Before Spinal Anaesthesia
This study aimed to evaluate the efficacy of ultrasound guided femoral 3 in 1 block versus the blind technique single shot fascia iliaca compartment block as an analgesia method in patients prior positioning for spinal…
- Trial name
- IKH (NCT03139617)
- Testing
- Fascia Iliaca Compartment Block (FICB), 3 in 1 femoral block (FNB)
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- Universiti Sains Malaysia
Osteoporotic Fractures
Optimization of Follow-up of Patients With Symptomatic Recent Osteoporotic Vertebral Fracture
The management of osteoporotic fractures has recently changed with the emergence of new programs dedicated to the diagnosis and treatment of osteoporosis.
- Trial name
- OPTIVERT (NCT03967704)
- Testing
- Life quality evaluation
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Fondation Hôpital Saint-Joseph