Clinical trials: Fractures
Transverse Fracture of Shaft of Tibia
Comparison of Interlock Nailing Versus Dynamic Compression Plating in Transverse Fractures of Tibia
Study aims to compare two treatment modalities for treatment of transverse fractures of tibia. One is Intramedullary interlocking nail and the other is dynamic compression plate.
- Trial name
- NCT04958564
- Testing
- DCP
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- District Headquarters Teaching Hospital Sahiwal
Osteoporosis, Fractures, Compression
Dynamic Magnetic Resonance (MR) Study in Evaluating the Vertebral Bone Marrow Perfusion and Its Related Research
The etiology and pathogenesis of osteoporosis has been extensively discussed. The relationship between bone blood circulation and the formation of bony trabeculae has been less understood.
- Trial name
- NCT00172224
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Laryngoscopy, Stress Response
Comparison of Stress Response Evoked by Conventional Versus Videolaryngoscope
Impact of using video laryngoscopy versus direct laryngoscopy technique in terms of improved hemodynamics post intubation and time taken for intubation.
- Conditions
- Laryngoscopy, Stress Response, Duration
- Trial name
- NCT07510542
- Testing
- Endotracheal Intubation through a Video Laryngoscope (VL), Endotracheal Intubation through a Direct Laryngoscope (DL)
- Where
- Pakistan
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Sindh Institute of Urology and Transplantation
Osteoarthritis, Knee, Fractures, Ununited
Modern Methods of Treatment and Diagnosis of Patients With Injuries and Diseases of the Musculoskeletal System
Brief Summary This clinical study investigates the safety and effectiveness of combining advanced regenerative therapies with personalized surgical technology for patients with delayed fracture healing (non-unions), knee…
- Conditions
- Osteoarthritis, Knee, Fractures, Ununited, Arthroplasty, Replacement, Knee
- Trial name
- MTDMS (NCT07628010)
- Testing
- Autologous Mesenchymal Stromal Cells Combined with Platelet-Rich Plasma, Patient-Specific 3D-Printed Surgical Instruments
- Where
- Ukraine
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zaporizhzhiya State Medical University
Unstable Lisfranc Fracture-dislocations of the Midfoot
A Comparison of Stainless Steel and Bioabsorbable Screw Fixation of Lisfranc Foot Injuries
The Lisfranc ligaments are a group of ligaments that connect the bones of the middle portion of the foot to each other. The Lisfranc ligaments allow for a normal and stable range of motion and shape to the foot.
- Trial name
- Lisfranc (NCT00985023)
- Testing
- Steel screw fixation of Lisfranc fracture-dislocation., Absorbable screw fixation of Lisfranc fracture-dislocations.
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Postoperative Pain
Femoral Nerve Block, Periarticular Nerve Group (PENG) Block, and Preoperative IV Fentanyl
The pericapsular nerve group block is a regional anesthetic technique described in 2018, developed primarily in total hip arthroplasties for postoperative analgesia with motor sparing benefits.
- Trial name
- NCT06537323
- Testing
- Femoral nerve block with0.25% bupivacaine guided by ultrasound., PENG block with0.25% bupivacaine guided by ultrasound., Preoperative IV fentanyl 100microgram
- Where
- Egypt
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Aswan University Hospital
Fractures
Intramedullary Devices for the Treatment of Unstable Pertrochanteric Fractures
The purpose of this study is to assess the differences between two different types of devices for the treatment of unstable pertrochanteric hip fractures.
- Trial name
- NCT02074969
- Testing
- Gamma Nail 3, PFNA
- Where
- Austria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Fracture, Forearm
Treatment of Stable Both-Bone Midshaft Forearm Fractures in Children
We create a randomized clinical trial between the treatment with above elbow armcast alone and the treatment of above elbow in combination with a short arm cast for stable midshaft both-bone forearm fractures.
- Conditions
- Fracture, Forearm, Midshaft, Child
- Trial name
- NCT00398242
- Testing
- above or below elbow cast for the last 3 weeks of treatment
- Where
- 2 sites in Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Colaris, Joost, M.D.
Stress Reaction, Behavior, Social
The Effects of Therapy Dogs on Child Biology and Behavior
The objective of this study is to apply a rigorous experimental design to test whether children's interactions with therapy dogs increase immediate prosocial behavior and reduce immediate biological response to stress.
- Trial name
- NCT03949569
- Testing
- Therapy Dog, Stuffed Toy Dog, 5 Minute Puppy Video
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Fibula Fracture
Weight Bearing for Fibular Fractures
It is common practice to restrict weight bearing after ankle fracture open reduction and internal fixation (ORIF) until week 6 postoperatively. However, controversy exists surrounding the optimal postoperative protocol.
- Trial name
- NCT04872296
- Testing
- Controlled Ankle Motion (CAM) boot, Physical Therapy
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Femur Neck Fracture, Arthroplasty Complications
Metal Ion Levels in Total Hip Arthroplasty (THA) With Modular Dual Mobility Cup Compared to Conventional THA
After total hip arthroplasty using an 'Modular Dual Mobility' acetabular cup, which is effective in reducing the risk of dislocation, one of the serious complications occurring after total hip arthroplasty, the blood metal ion…
- Trial name
- NCT05181566
- Testing
- Total hip replacement arthroplasty using modular dual mobility cup, Total hip replacement arthroplasty using conventional acetabular cup
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Infarction, Stroke
Polymorphisms in the Vitamin D System and Health
Polymorphisms in the vitamin D system appear to affect the serum 25(OH)D levels. If so one would expect these polymorphisms to be associated with vitamin D related conditions and diseases, which will be tested in the present…
- Conditions
- Infarction, Stroke, Diabetes, Fracture
- Trial name
- NCT01395303
- Where
- Norway
- Volunteers
- 9,700 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Osteoporosis
Opportunistic Fragility Fracture Risk Estimates From Radiographs
The proposed study will predict a patients' risk of having osteoporosis by using a combination of the IBEX BH (Bone Health) software outputs and other clinical risk factors such as age, gender, medical history and lifestyle.
- Trial name
- OFFER2 (NCT06110442)
- Testing
- IbexBH Software
- Where
- United Kingdom
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Lisfranc Fracture, Arthrodesis
The BFF Study- The Better to Fix or Fuse Study
The aim of the proposed study is to define the optimal treatment for Lisfranc fracture-dislocation, either primary arthrodesis (PA) or open reduction and internal fixation (ORIF), regarding the quality of life, complications…
- Conditions
- Lisfranc Fracture, Arthrodesis, Internal Fixation, Quality of Life
- Trial name
- NCT04519242
- Testing
- Surgery
- Where
- Netherlands
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Accidental Falls, Osteoporosis
Prevention of Falls and Its Consequences in Elderly People
Falls are an important risk factor for fragility fractures. Both are associated with the ageing process and as they rise also increase the risk of mortality, disability and dependency.
- Trial name
- PRECIOSA (NCT02617303)
- Testing
- OTAGO's exercises, COMMON PRACTICE
- Where
- 11 sites in Spain
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Injuries, Genetic Change
Candidate Gene Association Study With Injury in Elite Male Youth Football Players
Understanding how candidate genes, previously associated with injury susceptibility, influence the incidence of muscle, bone, ligament, and tendon injuries across the development pathway of elite footballers may provide valuable…
- Trial name
- NCT04952662
- Testing
- Genetic variants
- Where
- 2 sites in United Kingdom
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Cognition, Stress Reaction
rTMS to Enhance Cognitive Performance and Promote Resilience
The purpose of this study is to determine the most effective dose of brief, non-invasive brain stimulation (repetitive transcranial magnetic stimulation, rTMS) for improving cognitive functions such as attention and memory as…
- Trial name
- NCT04123496
- Testing
- rTMS
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Distal Radius Fracture
Bier's Block Versus Systemic Analgesia
Background: There are three methods for procedural sedation in upper extremity traumas; systemic, regional and local anesthesia. There is controversy in the literature regarding the method of choice for this purpose.
- Trial name
- NCT03349216
- Testing
- Intravenous Regional Anesthesia, Systemic Analgesia
- Where
- Iran
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Osteoporosis of Disuse With Current Pathological Fracture
Associations Analysis Between Lifestyle and Osteoporosis
A large-scale, community-based, cross-sectional study was conducted to evaluate the extent to which lifestyle was associated with osteoporosis among the Chinese population by using self-reported questionnaire methods.
- Trial name
- NCT02451397
- Where
- 2 sites in China
- Volunteers
- 3,100 people, healthy volunteers welcome
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Distal Radius Fracture, Complication of Treatment
A Novel Splint Technique for Distal Radius Treatment
There are many conservative treatment methods, including below arm cast, above arm cast, and sugar tong splint that aim to obtain maximum functional, clinical, and radiological results There are no clear indications with regard…
- Trial name
- NCT04432740
- Testing
- Conservative Treatment of Distal Radius Fracture
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital