Clinical trials: Fractures in the Elderly
Fractures
Low-magnitude High-frequency Vibration Study on Fracture Rate in Community Elderly
Fragility fracture is common due to global aging problem, incurring huge healthcare expenditure. The occurrence of fragility fracture is usually caused by a fall incidence of an elderly with low bone quality and poor balancing…
- Trial name
- NCT00973167
- Testing
- Low-magnitude high-frequency vibration treatment
- Where
- China
- Volunteers
- 704 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery
The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury
In this prospective, randomized, single-blind study, we aim to compare the effects of general anesthesia and spinal anesthesia on postoperative myocardial injury in elderly patients undergoing hip surgery.
- Conditions
- Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery, Anesthesia, General, Anesthesia, Spinal
- Trial name
- NCT06343259
- Testing
- General Anesthesia, Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Hip Fractures, Stroke
Accuracy Activity Monitors for Inhospital Activity Monitoring of Geriatric Patients
The focus of this study will be to determine the accuracy of the MOX, the Axivity and Fitbit, Empatica and Chill+ activity monitors (with both custom-made and available algorithms) for the classification of lying, sitting…
- Conditions
- Hip Fractures, Stroke, Abdominal Injury
- Trial name
- NCT04865627
- Testing
- activity monitor
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- KU Leuven
Fracture of Neck of Femur, Resumption of Walking
Prognostic Impact of Neopterin on Resumption of Walking After a Fracture of the Upper Neck of the Femur in the Elderly
Society faces a major challenge with the management of the health and socio-economic burden caused by acute physical stress in the older population (>75 years).
- Trial name
- MAMI (NCT05233072)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Radius Fractures, Aged
Cost-effectiveness, Volar Locking Plate or Non-operative Treatment Distal Radius Fracture
A cost-utility analysis based on an earlier published RCT comparing surgery with volar locking plate to non-operative treatment for the elderly with a displaced distal radius fracture.
- Conditions
- Radius Fractures, Aged, Cost-Benefit Analysis, Wrist Fracture
- Trial name
- HE-VOCAL (NCT06067074)
- Testing
- Volar Locking Plate, Plaster Cast
- Where
- Sweden
- Volunteers
- 140 people
- Sponsor
- Karolinska Institutet
Accidental Falls, Osteoporosis
Prevention of Falls and Its Consequences in Elderly People
Falls are an important risk factor for fragility fractures. Both are associated with the ageing process and as they rise also increase the risk of mortality, disability and dependency.
- Trial name
- PRECIOSA (NCT02617303)
- Testing
- OTAGO's exercises, COMMON PRACTICE
- Where
- 11 sites in Spain
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Ankle Fractures
Factors Influencing the Risk of Surgical Site Infections and Wound Complications in Operatively Treated Ankle Fractures in the Elderly
This study is to analyse risk factors for wound complications or surgical site infections and to analyse whether risk factors for wound complications or surgical site infections are also factors for other complications.
- Trial name
- NCT04379791
- Testing
- Data collection from routine medical records
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University Hospital, Basel, Switzerland
Femoral Neck Fractures
Undisplaced Femoral Neck Fractures in the Elderly: A Trial Comparing Internal Fixation to Hemiarthroplasty
Clinical research during the last ten years has revealed that elderly patients with a displaced femoral neck fracture should be treated with arthroplasty instead of closed reduction of the fracture followed by internal fixation…
- Trial name
- NCT01770769
- Testing
- Hemi - arthroplasty, internal fixation
- Where
- Norway
- Volunteers
- 220 people
- Sponsor
- University Hospital, Akershus
Insulin Resistance, Elderly Patient
The Effect of Taurine on Morbidity and Mortality in the Elderly Hip Fracture Patient
The purpose of this study is to reduce the postoperative morbidity and mortality in the elderly hip fracture patient, by giving them taurine peri-operatively.
- Conditions
- Insulin Resistance, Elderly Patient, Oxidative Stress
- Trial name
- TAUP (NCT00497978)
- Testing
- taurine
- Where
- Netherlands
- Volunteers
- 236 people
- Sponsor
- Medical Center Alkmaar
Depression in Old Age, Fragility Fracture
Serotonin-norepinephrine Reuptake Inhibitor in Prophylaxis of Depression Following Fragility Fractures
The goal of this pilot study is to learn about the feasibility about prescribing anti-depressants at discharge in patients aged 50 years and older with a lower extremity fragility fracture.
- Trial name
- SNRI (NCT05851898)
- Testing
- Duloxetine 30 mg
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wake Forest University Health Sciences
Delirium
Hip Fracture Surgery in Elderly Patients
The objective of this study is to evaluate the incidence of Post-Operative Delirium (POD), diagnosed with the Confusion Assessment Method (CAM), in elderly patients undergoing hip fracture surgery under general anaesthesia with…
- Trial name
- HIPELD (NCT01199276)
- Testing
- Xenon, Sevoflurane
- Where
- 13 sites in Belgium, France and 4 more
- Volunteers
- 256 people
- Sponsor
- Air Liquide Santé International
Delirium, Elderly Patient
Evaluation of the Efficiency of Neutrophil-Lymphocyte Ratio in Predicting Delirium in Geriatric Patients Undergoing Hip Fracture Surgery
Aim: Postoperative delirium (POD) is one of the most common complications in elderly patients and is associated with increased morbidity, mortality, length of hospital stay and medical care costs.
- Conditions
- Delirium, Elderly Patient, Hip Fracture Surgery, Neutrophil Lymphocyte Ratio
- Trial name
- NCT07741175
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Radius Fracture Distal
Lets Agree to Disagree on Operative vs Nonoperative Treatment for Distal Radius Fractures in the Elderly (LADON Radius)
The primary objective of this study is to determine if non-operative treatment of distal radius fractures in patients aged 65 and over leads to equal funtional results as operative treatment.
- Trial name
- LADON radius (NCT05631314)
- Testing
- operative treatment, non-operative treatment
- Volunteers
- 110 people
- Sponsor
- Luzerner Kantonsspital
Shoulder Fractures, Intramedullary
Operative Treatment of 2-fragment-fractures (AO 11-A3) of the Proximal Humerus in the Elderly: Cement Augmented Locking Plate Philos vs. Proximal Humerus Nail MultiLoc
Proximal humeral fractures are with an incidence of 4-5% the third most common fractures in the elderly. Compared to fractures of the upper limb it is the second most common fracture after distal radial fractures.
- Conditions
- Shoulder Fractures, Intramedullary, Bone Plates
- Trial name
- NCT02609906
- Testing
- PhilosTM with augmentation (Depuy-Synthes), MultiLoc®-Nail (Depuy-Synthes)
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- LMU Klinikum
Cognitive Decline, Delirium
CITADEL: Effectiveness of CITicoline in Preventing Cognitive Decline After DELirium
The aim of this study is to assess whether citicoline (TRAUSAN), a neuroprotective agent involved in membrane phospholipid synthesis and neurotransmission, can prevent or attenuate cognitive decline in older adults who develop…
- Trial name
- CITADEL (NCT07804498)
- Testing
- Citicoline
- Where
- Italy
- Volunteers
- 122 people
- Sponsor
- University of Milano Bicocca
Hip Fractures, Elderly Patients
Comparison of Phenylephrine and Ephedrine in the Treatment of Hemodynamic Disorders After Spinal Anesthesia in the Elderly
Spinal anesthesia is often used for lower limb surgery in elderly. Hypotension is a side effect of spinal block. In this study, intravenous ephedrine and phenylephrine will be compared with each other to prevent spinal…
- Conditions
- Hip Fractures, Elderly Patients, Spinal Anesthesia, Lower Limb Surgery
- Trial name
- HypoGer (NCT03858465)
- Testing
- Ephedrine, Phenylephrine
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Warsaw
Fragility Fractures of the Pelvis (FFP)
Robot Assisted Minimally Invasive Treatment Versus Conservative Treatment for Fragility Fractures of the Pelvis Type 1-2 in Elderly Patients
This prospective randomized controlled trial aims to compare the efficacy and safety of robot assisted minimally invasive treatment versus conservative treatment in elderly patients with FFP1-2 fragility fractures of the pelvis.
- Trial name
- FFP (NCT07636616)
- Testing
- Robot Assisted Minimally Invasive Fixation
- Volunteers
- 152 people
- Sponsor
- Junbo Liang
Sarcopenia, Frailty
Using Exergame-based Program in Elders of Rural LTCF
Background: Sarcopenia is the progressive loss of skeletal muscle mass and decline of muscle function associated with aging. Frailty is defined as a clinically recognizable state of increased vulnerability resulting from…
- Conditions
- Sarcopenia, Frailty, Long Term Care Facility
- Trial name
- NCT05360667
- Testing
- Standard care plus plus Exergame-based multicomponent training program, Standard care
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Cishan Hospital, Ministry of Health and Welfare
Hip Fractures
Effect of a Robotic Platform for Hip Fracture Rehab
Hip fracture is one of the most common traumas associated with falls in the elderly, severely affecting the patient's mobility and independence.
- Trial name
- NCT05079555
- Testing
- Robotic rehab
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Werium Assistive Solutions
Patella Fracture, Aging
Patella Fracture : A Randomized Controlled Trial
This is a multi-centre, randomized controlled trial comparing operative and non operative treatment for displaced patella fractures in elderly, low-demand patients.
- Trial name
- NCT03445819
- Testing
- Group A: Surgical Treatment, Group B: Conservative Treatment
- Where
- 3 sites in Canada
- Volunteers
- 84 people
- Sponsor
- Unity Health Toronto