Clinical trials: Fractures in the Elderly
Odontoid Fracture
Randomized, Controlled Trial of Posterior C1-2 Fusion Versus Bracing Alone for Treatment of Type II Odontoid Process Fractures in the Elderly
This prospective study addresses one of the most controversial topics in the treatment of cervical spine trauma: the management of type II odontoid process fractures in the elderly.
- Trial name
- NCT03788200
- Testing
- Bracing, posterior C1-C2 instrumented fusion
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Rothman Institute Orthopaedics
Cognitive Deterioration
Pain Management in Elderly Patients With or Without Cognitive Frailty Hospitalized "ALGOGER"
Today, the standard treatment is to operate on patients suffering from a fracture of the upper end of the femur. The aim of treatment is to enable immediate mobilization and weight-bearing, and as rapid a return as possible to…
- Trial name
- ALGOGER (NCT06056934)
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Sepsis, Osteoporotic Hip Fracture
Prediction of Mortality and Morbidity After Hip Fracture Using Monocyte Distribution Width (MDW)
Hip fracture is a common injury in older adults and is often associated with serious complications, longer hospital stays, and increased risk of death.
- Conditions
- Sepsis, Osteoporotic Hip Fracture, Hip Fracture
- Trial name
- MDW (NCT07350785)
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- National and Kapodistrian University of Athens
Postoperative Delirium
Naples Prognostic Score for Predicting Postoperative Delirium
Naples Prognostic Score (NPS) originally developed to predict outcomes in inflammatory and malignant conditions; we asked if it can effectively predict postoperative delirium (POD) in elderly patients undergoing hip surgery? NPS…
- Trial name
- NCT07297017
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- South Valley University
Hip Fracture, Malnutrition
GNRI and Rectus Femoris Muscle Thickness in Older Patients Undergoing Hip Fracture Surgery
This prospective observational study will evaluate whether nutritional risk and reduced muscle mass are associated with postoperative outcomes in adults aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Hip Fracture, Malnutrition, Sarcopenia, Postoperative Complications
- Trial name
- NCT07751692
- Testing
- Geriatric Nutritional Risk Index Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Delirium, Femoral Fracture
Family Caregiver Role in Decreasing Delirium in Older Patients With Fractured Femur Using HELP Principles.
The Hospital Elder Life Program (HELP) has been shown to reduce delirium in hospitalized patients. In this study a family caregiver will apply the principles of the HELP program in a structured manner following training by a…
- Trial name
- FamHelp (NCT05321771)
- Testing
- Family caregiver application of HELP principles
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Rambam Health Care Campus
Delirium in Old Age, Fragility Fracture
Use of Anesthetic Block for the Prevention of in Hospital Delirium in Patients of the Orthogeriatric Clinical Care Center of the HUFSFB and HUSJI From 2019 - 2020
The purpose of this study is to identify the association between analgesic management with blockade of the iliac fascia versus intravenous analgesia with the presence of delirium during hospital stay in patients admitted to the…
- Conditions
- Delirium in Old Age, Fragility Fracture, Hip Fractures
- Trial name
- NCT04654962
- Testing
- Anesthetic nerve block
- Where
- Colombia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Fundación Santa Fe de Bogota
Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures)
Cohort Study on the Prognosis and Influencing Factors in Elderly Patients With Hip Fractures in Multicenter of China
To address the difficulties and problems currently facing large-scale clinical cohort studies in China, and on the basis of the existing project "Construction of Clinical Registration Database and Risk Assessment System for…
- Trial name
- NCT07847164
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Beijing Hospital
Hip Fractures (ICD-10 72.01-72.2)
Risk Early Warning Management for Postoperative Hip Fracture Rehabilitation and Delirium Prevention in Elderly Patients
This clinical study aims to evaluate the effectiveness of a perioperative risk early warning management strategy in patients undergoing surgical treatment for hip fractures.
- Trial name
- NCT06966947
- Testing
- Risk Early Warning Management, Standard Perioperative Care
- Where
- China
- Volunteers
- 284 people
- Sponsor
- People's Hospital Affiliated to Hubei University of Medicine
Coxarthrosis; Primary, Coxarthrosis; Post-Traumatic
Cemented TrendHip® - Multicenter PMCF Study on Total Indications
This Post Market Clinical Follow-Up (PMCF) study to evaluate the performance and safety of the cemented TrendHip® stem in a prospective follow-up study with patients who underwent a hip arthroplasty with the investigational…
- Conditions
- Coxarthrosis; Primary, Coxarthrosis; Post-Traumatic, Necrosis, Femur Head, Rheumatoid Arthritis
- Trial name
- TRESTI (NCT04943328)
- Testing
- Total Hip Arthroplasty
- Where
- 4 sites in Germany
- Volunteers
- 119 people
- Sponsor
- Aesculap AG
Hip Fractures
Protein and Carbohydrate Loading in Elderly With Hip Fractures
Pre-operative carbohydrate and protein loading among older people with hip fractures could potentially influence patient outcomes.
- Trial name
- NCT04614181
- Testing
- Nestle Resource drink, Usual care
- Where
- Malaysia
- Volunteers
- 34 people
- Sponsor
- University of Malaya
Fracture, Influenza Vaccination
Influenza Vaccination Against Infectious Complications and Mortality in Older Adults With Fractures: a Large-scale Retrospective Cohort Study
Background: Both influenza and bone fractures are significant contributors to morbidity and mortality among older adults. This study evaluated the associations between influenza vaccination (IV) and adverse outcomes following…
- Trial name
- NCT07231016
- Where
- Taiwan
- Volunteers
- 561,566 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Hospital
Femur Intertrochanteric Fractures
Partial Weight Bearing Proximal Femoral Nail Due to Intertrochanteric Fracture.
Femur intertrochanteric fractures (FITC) are one of the most common fractures of the lower extremity, caused by osteoporosis, caused by minor trauma in elderly patients.
- Trial name
- randomized (NCT05602155)
- Testing
- Group 1, Group 2
- Where
- Turkey (Türkiye)
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Anesthesia; Reaction
Study of Nerve Block Anesthesia for Surgery of Hip Fracture in the Elderly
The investigators aim to examine target-controlled propofol infusion as a technique of anesthesia for surgery of hip fracture under ultrasound guidance lumbar and sacral plexus block or lumbar, sacral and paravertebral nerve…
- Trial name
- NCT02104908
- Testing
- paravertebral nerve, lumbar and sacral plexus block
- Volunteers
- 80 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Odontoid Fracture, Elderly
SCORE Study: Comparing Surgery and Rigid Collar Treatment for Odontoid Fractures in Adults Over 70
The goal of this clinical trial is to compare two treatment options-surgery or rigid collar bracing-for unstable neck fractures (odontoid fractures) in adults aged 70 years and older.
- Trial name
- NCT06961578
- Testing
- C1-2 instrumentation, External immobilization with rigid cervical collar
- Where
- 16 sites in Germany
- Volunteers
- 322 people
- Sponsor
- Technical University of Munich
Proximal Humeral Fractures, AO/OTA (2007) Group B2 and C2
Displaced Proximal Humeral Fractures: Delta Prothesis or Philos Plate?
To investigate the assumption that reversed shoulder prosthetic replacement will give a better functional outcome compared to open reduction and internal fixation with an angular stable plate in displaced proximal humeral…
- Trial name
- DELPHI (NCT01737060)
- Testing
- Reverse total shoulder arthroplasty
- Where
- Norway
- Volunteers
- 124 people
- Sponsor
- Oslo University Hospital
Fracture;Elbow
Strength After Elbow Fractures in the Elderly
Elderly patients strength and function, specifically the ability to rise from a seat after either operative or non operative treatment of an mayo type 2 olecranon fracture.
- Trial name
- STAND-UP (NCT05135949)
- Testing
- Patient Reported Outcomes, Strength Test
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Fraser Orthopaedic Research Society
Hip Fractures
Hypobaric Lateral Spinal Anesthesia Versus General Anesthesia for the Hip Fracture Surgery
Hip fracture is a frequent pathology, involving elderly patients with many co-morbidities ; therefore, post-operative morbidity and mortality is high.
- Trial name
- RACHYP (NCT03373864)
- Testing
- Unilateral spinal anesthesia, General anesthesia
- Where
- France
- Volunteers
- 154 people
- Sponsor
- Hospices Civils de Lyon
Neck Injuries, Spinal Injuries
Treatment of Type II Odontoid Fractures Among the Elderly
The purpose of this study is to compare the safety and effectiveness of surgical versus conservative management of type II odontoid fractures among patients > 64 years of age.
- Trial name
- NCT00266929
- Testing
- surgical, conservative treatment
- Where
- 15 sites in United States, Canada
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- AOSpine North America Research Network
Shoulder Fractures
Conservative vs Surgical Treatment for Proximal Humerus Fractures in the Elderly
This is a randomized trial comparing conservative with surgical treatment (with open reduction and locking plate fixation) for proximal humeral fractures in patients aged more than 60 years.
- Trial name
- NCT02913378
- Testing
- Osteosynthesis with locking plate, Sling
- Where
- Brazil
- Volunteers
- 58 people
- Sponsor
- University of Sao Paulo