Clinical trials: Frail
Heart Failure With Preserved Ejection Fraction, Sarcopenia
Effectiveness of a Cardiac Rehabilitation Program in Elderly Patients With Heart Failure.
The main objective of the study is to assess the effectiveness of a cardiac rehabilitation program on functionality, measured by kinematic analysis, cardiorespiratory capacity, and ventricular ejection fraction in elderly…
- Conditions
- Heart Failure With Preserved Ejection Fraction, Sarcopenia, Frail Elderly Syndrome, Comorbidities and Coexisting Conditions
- Trial name
- FUNNEL+ (NCT05393362)
- Testing
- Cardiac Rehabilitation Program (CR), Control Group (CG)
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- University of Malaga
Elderly Inpatients, Frail
Prevalence and Influencing Factors of Frailty in Elderly Patients With Heart Failure
The goal of this observational study is to investigate the prevalence and associated factors of frailty in hospitalized elderly patients with heart failure.
- Conditions
- Elderly Inpatients, Frail, Heart Failure Hospitalization, CGA
- Trial name
- NCT07510035
- Where
- China
- Volunteers
- 298 people
- Sponsor
- Zhejiang Hospital
Frail Elderly People Hospitalized
Predictors of Physical Improvement in Frail Hospitalized Elders After Nutrition and Exercise
This study aims to evaluate whether a 12-week program combining oral nutritional supplements (ONS) with resistance exercises can improve nutritional status, muscle strength, and physical mobility in hospitalized older adults with…
- Trial name
- NCT07429630
- Testing
- Combined ONS and Resistance Training Program
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhejiang Hospital
Dementia, Hip Fracture
Communication for Early Mobilisation of People Living With Dementia Following Surgery for Hip Fracture
This goal of this study is to identify ways that healthcare professionals communicate that are effective in helping a person living with dementia to stand or walk after surgery for a broken hip (hip fracture).
- Conditions
- Dementia, Hip Fracture, Early Mobilisation, Communication Research
- Trial name
- VOICE-HF (NCT07418268)
- Volunteers
- 200 people
- Sponsor
- University of Nottingham
Frail Elderly
Community-Based Program Integrating Nurse-Led Mind-Body Exercise and Nutrition for Frailty
This study aims to develop and evaluate a community-based rehabilitation program integrating nurse-led mind-body exercises and nutritional supplementation for frail older adults in Indonesia.
- Trial name
- N-CARE Frailty (NCT07418762)
- Testing
- Nurse-Led Mind-Body Exercise (MBE)
- Where
- Indonesia
- Volunteers
- 48 people
- Sponsor
- Universitas Airlangga
Rehabilitation Frail Elderly Subjects
Study of the Impact of Implicit Motor Training in a Rehabilitation Programme in Frail Elderly Subjects
Even though cognitive-motor performances are impaired in frail elderly subjects compared with healthy elderly subjects, exercising cognitive-motor processes in an implicit manner can improve the carrying out of real actions in…
- Trial name
- MAAMI (NCT02855853)
- Testing
- serious game et virtual reality, Nintendo Wii
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Frail, Sensorimotor Deficits
Cognitive-motor Technology Rehabilitation in Frail Individuals
Dual performance, which involves the simultaneous execution of motor and cognitive tasks, is a fundamental aspect of everyday functioning.
- Trial name
- FIT4COG (NCT07292428)
- Testing
- Technological rehabilitation with robotic platfom and home telerehabilitation device, Conventional rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Frailty, Frail Elderly
Synergizing Home Health Rehabilitation Therapy
The objective of this project is to pilot test an ADL (activities of daily living)-enhanced program as an adjuvant therapy to usual home health rehabilitation to improve patient outcomes.
- Conditions
- Frailty, Frail Elderly, Occupational Therapy, Activities of Daily Living
- Trial name
- NCT05411393
- Testing
- ADL-enhanced program, Usual home health rehabilitation therapy
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Florida
Frail Elderly Syndrome, Mild Cognitive Impairment
Spanish Linguistic Validation, Validity and Reliability Test of Frail´BESTest in Elderly Institutionalized Frail People
The aging of the global population presents significant social and health challenges. In Aragón, 15% of the population is between 65 and 79 years old, and the over-aging index is 16.6%, higher than the national average.
- Trial name
- NCT06438718
- Where
- Spain
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Exergaming, Exercise Therapy
Comparative Effects Of Exergaming And Otago Exercise On Anticipatory Postural Control And Sensory Integration In Older Adults
This study explores whether non-immersive, interactive Exergaming using Xbox Kinect can go beyond conventional exercise by actively training the brain and body to react faster, balance smarter, and move more confidently.
- Conditions
- Exergaming, Exercise Therapy, Frail Elderly, Healthy Aging
- Trial name
- NCT07308353
- Testing
- Otago Exercise Program, Exergaming
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Frailty, Frail Elderly Syndrome
Education for Prevention and Treatment of Frailty
Frailty is a condition with a high prevalence in older adults, leading to higher vulnerability and increasing the risk of adverse health outcomes and disabilities.
- Trial name
- FRAGSALUD (NCT05610605)
- Testing
- Health intervention programme: FRAGSALUD
- Where
- Spain
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Frail Elderly People Hospitalized
Evaluation of the Hospital Pathway for Frail Elderly Patients Hospitalised for Pathologies Leading to Medical Decompensation
People aged over 75 account for 25% of emergency department visits in the Provence Alpes Côte d'Azur region. Depending on the facility, around 50% of these patients are discharged home without being hospitalised.
- Trial name
- FRAGIL (NCT06873256)
- Where
- France
- Volunteers
- 310 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Frail Elderly, Dual Task Exercises in Elderly People
FreeFrail Project: A Multicomponent Intervention for the Management of Frailty in Primary Care: A Randomized Controlled Trial
The primary aim is to assess the effectiveness of a multicomponent intervention including dual-task exercise in improving functionality and cognitive performance and in reducing frailty among community-dwelling adults aged ≥65…
- Conditions
- Frail Elderly, Dual Task Exercises in Elderly People, Exercise Training, Frailty
- Trial name
- NCT07205016
- Testing
- Dual task exercise, Otago exercise
- Volunteers
- 220 people
- Sponsor
- Universitat de Lleida
Mildly Frail, Fragile and More Vulnerable
Using a Technology Assisted Physical Activity Program to Improve Muscle Strength, Joint Mobility, Standing Time,Self-efficacy and Life Satisfaction of Residents in Institutions
This study aims to examine the effectiveness of a technology-assisted physical activity program on improving muscle strength, joint mobility, standing time, self-efficacy, and life satisfaction among residents in institutions.
- Trial name
- NCT07199400
- Testing
- physical activity program
- Where
- Taiwan
- Volunteers
- 51 people
- Sponsor
- National Taiwan Normal University
Frail Elderly Syndrome
The Importance of Anesthesia Method in Fragile Patients
The aim of this study is to comparatively evaluate the effects of different anaesthesia methods (spinal anaesthesia and general anaesthesia) administered to frail elderly patients scheduled for transurethral surgery (e.g.
- Trial name
- NCT07191769
- Testing
- general anaesthesia, regional anaesthesia
- Volunteers
- 180 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Frail Elderly Syndrome, Malnutrition Elderly
Effect of a Combined Exercise and Anti-Inflammatory Nutritional Intervention in Frail Older Adults
The goal of this clinical trial is to evaluate whether a combined intervention of therapeutic exercise and anti-inflammatory nutritional supplementation improves physical performance and reduces systemic inflammation in frail…
- Trial name
- AliFrail (NCT07182292)
- Testing
- Anti-Inflammatory Supplement, Conventional Nutritional Supplement
- Volunteers
- 158 people
- Sponsor
- Fundacion Miguel Servet
Cognitive Impairment, Frail Older Adults
Cognitive Fraility and Biomarkers in Older Patients
this study aimed to investigate the association between cognitive fraility and selected plasma and cerebrospinal fluid biomarkers related to neurodegenetaion and neuroinflammation in older adult patients undergoing elective…
- Conditions
- Cognitive Impairment, Frail Older Adults, Orthopaedic Surgery
- Trial name
- NCT07184073
- Testing
- assessment Mini mental state examination, assessment FRAIL scale, collecting cerebrospinal fluid during regional anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 129 people
- Sponsor
- Baskent University
Frail
AI-Assisted Rehabilitation In Frailty
This study investigates the effectiveness and implementation of an AI-assisted rehabilitation tool for adults with frailty in the real-world.
- Trial name
- NCT07176520
- Testing
- AI-assisted rehabilitation, usual care only
- Volunteers
- 220 people
- Sponsor
- SingHealth Community Hospitals
Frail Elderly Syndrome, Aging
Autologous Stem/Stromal Cellular Stromal Vascular Fraction (cSVF) In Frailty-Aging Processes
With increasing age and health issues associated with aging, many systemic cellular and structural changes are known to occur. The intent of this trial is to determine the safety and efficacy of delivery of autologous cellular…
- Conditions
- Frail Elderly Syndrome, Aging, Degenerative Disease
- Trial name
- GARM-W (NCT03514537)
- Testing
- Microcannula harvest adipose stromal tissues, Centricyte 1000, Sterile Normal Saline IV Deployment of cSVF
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Healeon Medical Inc
Cognitive Decline, Urinary Bladder Cancer
Association of POCD With Circulating Biomarkers in Patients Undergoing TUR of Bladder Tumor
Bladder tumor is one of the most widespread tumors in the world, with increasing prevalence at the global level. One of the procedures in patients with bladder tumors is transurethral resection of the bladder (TURM) most often…
- Conditions
- Cognitive Decline, Urinary Bladder Cancer, Frail, Biomarker
- Trial name
- NCT07165236
- Where
- Croatia
- Volunteers
- 42 people
- Sponsor
- Osijek University Hospital