Clinical trials: Frail Elderly Persons
Frailty, Muscle Weakness
Effectiveness of Protein Supplementation on Frailty Improvement, Muscle Strength and Physical Performance Among Pre-Frail Elderly People
The goal of this randomized clinical trial is to study the effectiveness of protein supplements in frailty improvement, muscle strength, physical performance, energy intake and body composition of pre-frail elderly people.
- Conditions
- Frailty, Muscle Weakness, Physical Dependence, Weight Loss
- Trial name
- NCT05648617
- Testing
- SUSTINEX Hydrolyzed Whey Protein
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Frail Elderly Syndrome
HOPE (Healthy Older People Everyday) To Age in Place
Certain clinical syndromes eg frailty, sarcopenia, dementia, depression, cognitive impairment, vision impairment, falls in older adults carry an increased risk for poor health outcomes and if identified early, can be prevented…
- Trial name
- NCT03797352
- Testing
- Multicomponent exercise
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Polypharmacy
Structured Polypharmacy Management Before Elective Non-cardiac Surgery in Frail and Elderly People
The older segment of the population is growing faster than any other segment. Older people have surgery more often than any other age group, and these older patients often take multiple medications, including medications that may…
- Trial name
- NCT03445767
- Testing
- MedSafer
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Frail Elderly, Exercise Therapy
A Multi-component Intervention in Frail Community-dwelling Older People
This study evaluates if a multi-component intervention, respecting the characteristics of frail older person and increasing intensity and challenge of exercises according to frail older person capacity/evolution will induce…
- Conditions
- Frail Elderly, Exercise Therapy, Physical Therapy Techniques
- Trial name
- MIF (NCT02918682)
- Testing
- Exercise - FIRST PHASE, Exercise - SECOND PHASE, Exercise - FOURTH PHASE
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Sarcopenia, Frailty
Resistance Exercise Training at Different Intensities
The aim of the current study, therefore, is to determine the feasibility of recruitment and adherence to resistance exercise training interventions performed at low and high loads, to volitional muscular failure, in a trial…
- Conditions
- Sarcopenia, Frailty, Aging
- Trial name
- NCT04053920
- Testing
- Low Load Resistance exercise, High Load Resistance exercise
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Frailty, Frail Elderly Syndrome
Education for Prevention and Treatment of Frailty
Frailty is a condition with a high prevalence in older adults, leading to higher vulnerability and increasing the risk of adverse health outcomes and disabilities.
- Trial name
- FRAGSALUD (NCT05610605)
- Testing
- Health intervention programme: FRAGSALUD
- Where
- Spain
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Frailty, Mobility Limitation
Feasibility of WB-EMS in Frail Older People
Exercise in general and resistance training (RT) in particular have demonstrated positive effects on physical functioning and frailty.
- Trial name
- NCT04495647
- Testing
- Whole-Body Electromyostimulation
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Frail Elderly Syndrome
Multifactorial Fall Prevention Program
The main objective is evaluate the effectiveness of a Multifactorial Pilot Program on the Prevention of Falls in people aged 65 or over during 4 years at Gerencia de Atención Integrada de Talavera de la Reina.
- Trial name
- Dodgers (NCT05682872)
- Testing
- Physical exercise program (VIVIFRAIL) supervised by a physiotherapist, Adequacy of the environment, Polypharmacy review
- Where
- Spain
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Castilla-La Mancha Health Service
Old Age; Debility
Thermal Imaging in Old and Frail in the Community
This study aims to test whether infrared thermal imaging using a non-touch, non-ionising, thermal camera system is feasible and reliable as an independent technique for thermal comfort assessment in older people and frail older…
- Trial name
- NCT03884218
- Testing
- Infra red thermal imaging
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Frailty, Frailty Syndrome
Characterising Frailty Using Magnetic Resonance Imaging
Ageing is associated with the development of various negative conditions, such as frailty. Defined as a decreased ability to combat negative stressors (e.g.
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome
- Trial name
- PHENOFRIM (NCT04612686)
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Frail Elderly Syndrome
Resistance Exercise Training at Different Intensities in Healthy and Frail Older People: A Feasibility Study
After the age of 40-45 years muscle mass and function progressively decline, reducing older peoples' abilities to perform tasks of daily living and also increase the risk of falls.
- Trial name
- NCT03627793
- Testing
- resistance training
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Frail Elderly Syndrome, Sarcopenia
Physical Fitness, Body Composition and Frailty in Elderly People.Exercise Program Effecsts. EXERNET Elder 3.0
One of the major changes occurring in developed societies is a significant ageing of the population. Nowadays, because of an enhanced life expectancy, 17% of the Spanish population is composed of people over 65 and the number is…
- Conditions
- Frail Elderly Syndrome, Sarcopenia, Physical Activity
- Trial name
- EXERNETElder (NCT03831841)
- Testing
- Multicomponent exercise programe
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Undernutrition, Rehabilitation
An Innovative Rehabilitating Meals-on-wheels Service for Frail Old People
The aim of the project is to assess the beneficial effect of offering frail old people a targeted meals-on-wheels service in 8 weeks in a randomized controlled trial
- Trial name
- NCT03889184
- Testing
- rehabilitating meals-on-wheels service
- Where
- Denmark
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Accidental Falls
Effect on Falls Reduction of a Multimodal Intervention in Frail and Pre-frail Elderly Community-dwelling People
Practice guidelines in caring for the geriatric population recommend performing an annual screening of falls . However, one of the problems that interfere with fall prevention programs is the lack of importance accorded to health…
- Trial name
- FAREMAVA (NCT02631330)
- Testing
- Multicomponent physical activity
- Where
- Spain
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- Hospital de la Ribera
Frail Elderly Syndrome, Nutrition Disorders in Old Age
The Effects of the Oral Nutritional Supplement With β-hydroxy-β-methylbutyrate in Lean Body Mass Among Taiwan Elderly
Primary objective: To evaluate the effects of additional oral nutritional supplement containing β-hydroxy-β-methylbutyrate (HMB) on thigh muscle mass in elderly subjects with pre-frail status Secondary objectives: 1.
- Conditions
- Frail Elderly Syndrome, Nutrition Disorders in Old Age, Muscle Loss
- Trial name
- NCT03792711
- Testing
- Ensure® Plus Advance
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Frail Elderly Syndrome
Protocols and Guidelines for the Use of Digital Twins in Frail Older People
The Proto-Aging study aims to define experimental protocols and guidelines to enable the development of musculoskeletal models (digital twins) of elderly people, with the ultimate goal to comprehensively characterize frail elders…
- Trial name
- Proto-Aging (NCT05854316)
- Testing
- Comprehensive Biomechanical assessment
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Frail Elderly Syndrome
Subjective Factors of Polymedication in the Elderly: a Qualitative Study of the Perceptions of Patients, Relatives and Referent Physicians.(DOSAGE)
The DOSAGE Study is a qualitative transversal study aiming to describe and understand the subjective factors of polymedication in the elderly population (75 years old and more), defined as 10 simultaneous drugs.
- Trial name
- DOSAGE (NCT03309228)
- Testing
- individual interviews
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Frailty
Prevention of Disability in the Frail Elderly Person Through an Innovative Customised and Multidimensional Training Programme
The goal of this clinical trial is to implement a personalized training program to prevent functional decline in frail subjects but not yet disable.
- Trial name
- PRAISE (NCT06377436)
- Testing
- Experimental training
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Milan
Frailty, Frailty Syndrome
Prevalence, Determinants and Natural History of Frailty and Pre-frailty in Elderly People
Frailty syndrome (i.e. frailty) is a geriatric syndrome which relies on the reduction of multisystem reserve capacity. Frail people have a lower potential to respond to external stressors and various life incidents as well as…
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome, Fragility
- Trial name
- FRAILPOL (NCT04518423)
- Where
- Poland
- Volunteers
- 1,093 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology
Frail Elderly Syndrome, Mild Cognitive Impairment
Spanish Linguistic Validation, Validity and Reliability Test of Frail´BESTest in Elderly Institutionalized Frail People
The aging of the global population presents significant social and health challenges. In Aragón, 15% of the population is between 65 and 79 years old, and the over-aging index is 16.6%, higher than the national average.
- Trial name
- NCT06438718
- Where
- Spain
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria Aragón