Clinical trials: Frail Older Adults
Frail Elderly
Effects of Remote Exercise on Physical Function in Pre-Frail Older Adults
This study aims to compare the effects of remote versus in-person exercise interventions on physical function, balance, gait stability, and fall efficacy in pre-frail older adults aged 65 years and above.
- Trial name
- NCT06672640
- Testing
- Remote Exercise Program, In-Person Exercise Program, Physical Activity Education
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Kyungdong University
Frail Elderly, Exercise Therapy
A Multi-component Intervention in Frail Community-dwelling Older People
This study evaluates if a multi-component intervention, respecting the characteristics of frail older person and increasing intensity and challenge of exercises according to frail older person capacity/evolution will induce…
- Conditions
- Frail Elderly, Exercise Therapy, Physical Therapy Techniques
- Trial name
- MIF (NCT02918682)
- Testing
- Exercise - FIRST PHASE, Exercise - SECOND PHASE, Exercise - FOURTH PHASE
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Frail Elderly Syndrome
Management of Frailty in Older Adults With Turmeric and Tulsi Supplements
The aim of this study is to determine the efficacy of turmeric and tulsi polyherbal formulation in the management of frailty in the elderly population.
- Trial name
- NCT03365310
- Testing
- C. longa, curcuminoids , Z. officianale, O. sanctum along with 200 ml of Milk, Standard of Care
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Composite Interceptive Med Science
Cognitive Decline, Urinary Bladder Cancer
Association of POCD With Circulating Biomarkers in Patients Undergoing TUR of Bladder Tumor
Bladder tumor is one of the most widespread tumors in the world, with increasing prevalence at the global level. One of the procedures in patients with bladder tumors is transurethral resection of the bladder (TURM) most often…
- Conditions
- Cognitive Decline, Urinary Bladder Cancer, Frail, Biomarker
- Trial name
- NCT07165236
- Where
- Croatia
- Volunteers
- 42 people
- Sponsor
- Osijek University Hospital
Frailty
Effect of an Exercise Program for Frail Older Adults
Despite the high level of evidence for physical activity as a countermeasure for frailty, the current Flemish standard of care does not include structural PA interventions for community-dwelling frail older adults.
- Trial name
- AA@HOME (NCT05946109)
- Testing
- ACTIVE-AGE@home
- Where
- Belgium
- Volunteers
- 195 people
- Sponsor
- Universitair Ziekenhuis Brussel
Frailty, Sarcopenia
Combining Nutrition Supplementation With an Exercise Program in Elderly Malnourished Frail Patients After Hospital Stay
The objective of this study is to investigate the feasibility of a combined nutritional and home-based exercise intervention in elderly, malnourished, frail patients after hospital discharge.
- Conditions
- Frailty, Sarcopenia, Malnutrition; Protein
- Trial name
- NCT05325697
- Testing
- Intervention consisting of a multicomponent exercise program combined with an oral nutritional supplement
- Volunteers
- 15 people
- Sponsor
- University Department of Geriatric Medicine FELIX PLATTER
Hip Fracture
Postoperative Blood Transfusion for Frail Elderly With Hip Fracture
Elderly with hip fractures are often frail and discharged from hospital after few days of hospitalisation. Hip fracture surgery is often associated with blood loss, where the patient is at risk of developing anaemia.
- Trial name
- NCT01102010
- Testing
- Blood transfusion
- Where
- Denmark
- Volunteers
- 284 people
- Sponsor
- University of Aarhus
Frail Elderly, Hip Fracture
Effects of Long-term Intensive Home-based Physiotherapy on Older People With an Operated Hip Fracture or Frailty (RCT).
Our objective is to study the effects of 12 months' intensive home-based physiotherapy (physical exercise) with 12 months' follow-up in two groups of older people: 1) those with an operated hip fracture (60+ y), and 2) those with…
- Trial name
- HIPFRA (NCT02305433)
- Testing
- Home-based physiotherapy (physical exercise)
- Where
- Finland
- Volunteers
- 421 people
- Sponsor
- South Karelia, Social and Health Care District
Geriatric Assessment, Frail Elderly
Drug Reduction in Older Patients: The DROP Trial
Project Objectives: The proposed randomized, controlled trial will evaluate the effects of procedures to reduce medications among hospitalized older Veterans discharged to nursing homes using an hybrid study design to inform…
- Conditions
- Geriatric Assessment, Frail Elderly, Skilled Nursing Facilities, Patient-centered Care
- Trial name
- DROP (NCT03722017)
- Testing
- Deprescribing intervention
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- VA Office of Research and Development
Nursing Homes, Aged
BABEL Advance Care Planning in Long-term Care
1.0 SUMMARY Most Canadian nursing home (NH) residents are elderly and frail, have multiple chronic health conditions and impairments, and have dementia.
- Conditions
- Nursing Homes, Aged, Frail Elderly Syndrome, Dementia
- Trial name
- BABEL (NCT03649191)
- Testing
- The BABEL Approach to Advance Care Planning in Nursing Homes, Control group Advance Care Planning
- Where
- 3 sites in Canada
- Volunteers
- 713 people
- Sponsor
- University of Manitoba
Postural Imbalance, Gait, Unsteady
A Device for Screening of Fall Risk in the Elderly
This study evaluates the screening accuracy of a device (OAK) in assessing fall risk in the elderly, compared to the assessment provided by the Algorithm for Fall Risk Assessment of the Centers for Disease Control and Prevention…
- Trial name
- NCT02655796
- Testing
- OAK
- Where
- Italy
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Frail Elderly Syndrome
Integrated Care for Frail Older People
This is a qualitative interview study investigating patients', carers' and providers' perspectives on integrated care and integrated care pathways for frail older people in Lambeth and Southwark, south London.
- Trial name
- NCT03260933
- Testing
- No intervention given. This is a qualitative interview study
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- King's College London
Frailty, Caregiver Burnout
Mindfulness-Based Intervention for Caregivers of Frail Older Chinese Adults
This is study to investigate the effects of a brief mindfulness-based program for frail older adults caregivers.
- Trial name
- NCT04861610
- Testing
- Brief mindfulness based program, Psychoeducation
- Where
- Hong Kong
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Frail Elderly, Malnutrition
Healthy Life for Frail Malnourished Seniors Performed Together With Trained Lay Buddies
Background: In elderly subjects frailty and malnutrition are very common and can lead to serious health hazards, increase mortality, morbidity, dependency, institutionalization and a reduced quality of life.
- Trial name
- NCT01991639
- Testing
- Nutritional and physical activity intervention
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Quality of Life
Anesthesia Geriatric Evaluation and Quality of Life After Peripheral Vascular Surgery
A prospective observational cohort study to assess the predictive value of preoperative frailty on postoperative quality of life in peripheral vascular surgery patients.
- Trial name
- AGE-VASC (NCT02820831)
- Where
- Netherlands
- Volunteers
- 88 people
- Sponsor
- St. Antonius Hospital
Type2diabetes, Frail Elderly Syndrome
The Impact of Geriatric Assessment on the Treatment Plan of Elderly Patients With T2DM
Introduction: With the aging of the world population and the increasing incidence of type 2 diabetes mellitus (T2DM) with age, the number of elderly individuals living with diabetes has been considerably rising.
- Conditions
- Type2diabetes, Frail Elderly Syndrome, Frailty, Geriatric Assessment
- Trial name
- NCT06469437
- Testing
- Providing the physicians with a proposed glycated hemoglobin target
- Where
- Brazil
- Volunteers
- 220 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Frail Elderly
A Pilot Study Comparing Effects of Nutrients Supplements and Dietary Approach in Frailty Management
The proportion of the elderly population has increased rapidly worldwide. Frailty is a common geriatric syndrome. Comprehensive dietary management strategy may have beneficial effects on frailty prevention and reversal.
- Trial name
- NCT02975089
- Testing
- "multi-nutrient" supplement, "multi-nutrient & soy protein" supplement, Nutrition education on balanced diet & food supplement
- Volunteers
- 40 people
- Sponsor
- Academia Sinica, Taiwan
Sarcopenia, Muscle Atrophy
Vitamin D and Resistance Exercise Training; Effects on Musculoskeletal Health in Frail Older Men and Women
This study aims to determine whether vitamin D3 supplementation is any more effective in improving musculoskeletal function when combined with exercise training compared with exercise training alone.
- Conditions
- Sarcopenia, Muscle Atrophy, Osteoporosis
- Trial name
- EXVITD (NCT02467153)
- Testing
- RET, Vitamin D3
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Disablement in the Elderly
Home-Based Technologies Coupled to Teleassistance Service in the Elderly
The growth of the elderly population is associated with the autonomy failure and the increase of dependence problems. Fall incidents are the third cause of chronic disablement in older persons and are one of the major risk…
- Trial name
- DOMOLIM (NCT01697553)
- Testing
- home automation pack coupled to teleassistance service, Home without automation pack coupled to teleassistance service
- Where
- 4 sites in France
- Volunteers
- 27 people
- Sponsor
- University Hospital, Limoges
Geriatric Assessment, Health Services for the Aged
Geriatric-CO-mAnagement for Cardiology Patients in the Hospital
The primary objective of the evaluation study is to determine if geriatric co-management is superior to standard of care in preventing functional decline in older patients admitted for acute heart disease or Transcatheter Aortic…
- Conditions
- Geriatric Assessment, Health Services for the Aged, Cardiovascular Diseases, Activities of Daily Living
- Trial name
- G-COACH (NCT02890927)
- Testing
- Cardio-geriatric co-management
- Where
- Belgium
- Volunteers
- 454 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven